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Butyl Thiocyanate

    • Product Name Butyl Thiocyanate
    • Alias Butyl sulfocyanate
    • Einecs 221-625-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    544555

    Chemicalname Butyl Thiocyanate
    Casnumber 1119-64-8
    Molecularformula C5H9NS
    Molarmass 115.20 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Strong, unpleasant odor
    Boilingpoint 173-174 °C
    Density 0.956 g/mL at 25 °C
    Solubility Insoluble in water, soluble in organic solvents
    Refractiveindex 1.466-1.468 at 20 °C
    Flashpoint 61 °C (closed cup)
    Meltingpoint -78 °C

    As an accredited Butyl Thiocyanate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Butyl Thiocyanate, 100 mL, supplied in an amber glass bottle with a secure screw cap, labeled with hazard and handling information.
    Shipping Butyl Thiocyanate should be shipped in tightly sealed containers, clearly labeled, and kept away from sources of ignition, heat, and incompatible substances. It must be transported according to hazardous materials regulations as it is flammable and toxic. Use UN-approved packaging and include necessary safety documentation and hazard communication labels.
    Storage Butyl Thiocyanate should be stored in a cool, dry, well-ventilated area away from heat, sparks, flames, and incompatible substances such as strong oxidizers and acids. Keep the container tightly closed and properly labeled. Store in a corrosive-resistant container and avoid exposure to moisture. Use appropriate secondary containment to prevent leaks or spills, and follow all chemical safety protocols.
    Application of Butyl Thiocyanate

    Applications of Butyl Thiocyanate in Industrial Manufacturing

    Butyl Thiocyanate serves as a specialized intermediate in selective industrial applications. As a dedicated manufacturer, we support its controlled use across key downstream sectors, delivering tailored material that aligns with technical and regulatory standards for high-value processes.

    1. Agrochemical Synthesis (Herbicide Intermediate)

    Major agrochemical companies use this raw material as a core intermediate in the synthesis of selective thiocyanate-based herbicides. Its integration begins at the early condensation stage where it offers unique reactivity patterns, especially for the alkylation of aromatic or heterocyclic cores. The compliance with specific guidelines ensures that impurities remain below critical thresholds affecting crop safety and environmental persistence.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 compliance for precursor registration and use
    • FAO/WHO guidelines for pesticide manufacturing inputs
    • ISO 9001:2015 certified processing systems
    • Integrated pest management (IPM) traceability documentation

    Typical usage ratio

    • 5%–18% by weight in the active ingredient synthesis step; precise dosage adjusted according to targeted molecular structure and impurity control

    Downstream process integration

    • Added during the initial alkylation or condensation phase in continuous or batch reactors before subsequent chlorination or sulfonation

    Final product types

    • Pre-emergence herbicide actives (e.g. phenylthiocyanate derivatives)
    • Broadleaf weed control products registered for cereal and oilseed crops
    • Selective vegetation management blends
    • Bulk herbicide technical concentrate for formulators

    2. Pharmaceutical Intermediate (API Synthesis)

    Chemical synthesis units specializing in active pharmaceutical ingredient (API) manufacturing source this intermediate for N-thiocyanation steps. It enables regioselective introduction of sulfur-containing functional groups, particularly in the production of certain cardiovascular and antimicrobial drug intermediates. Every lot undergoes trace analysis for pharmaceutical impurities and documentation for full regulatory traceability, per cGMP protocol.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US Pharmacopeia (USP) and European Pharmacopoeia (EP) monographs for critical impurities
    • FDA 21 CFR Part 211 process validation requirements
    • Full hazard communication under GHS/OSHA regulations

    Typical usage ratio

    • 0.8%–3.5% on a molar basis in heterocyclic scaffold functionalization; ratio depends on substrate reactivity and isolation yield targets

    Downstream process integration

    • Charged into the reactor during ring-closing or thiocyanation stages, followed by solvent removal and purification prior to API crystallization

    Final product types

    • Anti-anginal drug intermediates
    • Antibacterial synthetic precursors
    • Specialty generics with sulfanyl-modified active sites
    • Contract-manufactured pharmaceutical building blocks

    3. Rubber Accelerators Manufacturing

    Specialty elastomer factories apply this compound in the preparation of thiuram and sulfenamide-based rubber accelerators. Its sulfur donating ability allows precise regulation of vulcanization speed, enhancing process control for tire and industrial rubber goods. Batch processing follows strict raw material verification and effluent management protocols, as regulated in advanced rubber compounding facilities.

    Industry compliance standards

    • ASTM D4678 ‘Standard Practice for Rubber—Selection of Accelerators’
    • ISO 14001:2015 on environmental management for waste handling
    • China GB/T 21879—Rubber Chemicals Quality Standard
    • EU Directive 2011/65/EU (RoHS) for restricted substances exclusion

    Typical usage ratio

    • 1.0%–4.4% of rubber compound mass; determined by desired accelerator strength, sulfur concentration, and finished product cure profile

    Downstream process integration

    • Introduced during the compound mixing stage in banbury or open mill processes with direct addition to the masterbatch prior to vulcanization reactor feed

    Final product types

    • Radial tire rubber formulations
    • Conveyor belt elastomers
    • Industrial molded rubber gaskets
    • High-performance tube and hose products

    4. Flotation Agent Precursor in Mining Chemicals

    Mineral processing chemical suppliers incorporate this material as a precursor for synthesizing selective xanthate and thiocarbamate flotation agents. Its controlled reactivity profile enables selective sulfide ore recovery, especially in copper, lead, and zinc concentration plants. All batches meet sector-specific transport codes and are traceable for environmental safety evaluations per site.

    Industry compliance standards

    • UN Recommendations on Transport of Dangerous Goods (Orange Book)
    • OECD Guidelines for the Testing of Chemicals (mineral processing)
    • ISO 9001:2015 for chemical management system
    • Regulation (EC) No 1272/2008 (CLP) for hazard classification

    Typical usage ratio

    • 2.5%–9.0% in initial xanthate synthesis reaction mixture; adjusted as per target agent selectivity and ore complexity

    Downstream process integration

    • Reacted in dedicated flotation agent manufacturing lines during sulfurization and alkylation step, before agent dilution and packaging

    Final product types

    • Sodium isobutyl xanthate (SIBX)
    • Potassium amyl xanthate (PAX)
    • Thiocarbamate-based collector blends
    • Bulk flotation collector concentrates for mine sites

    5. Organic Synthesis for Perfume and Aroma Chemicals

    Fragrance ingredient manufacturers exploit the selective reactivity of this intermediate to introduce sulfur functionalities in custom aroma molecule synthesis. It acts at defined alkylation points, allowing perfumery chemists to build latent sulfur notes in top and base aroma profiles. Regulatory and QC procedures ensure the removal of off-odors and compliance with global fragrance safety guidelines.

    Industry compliance standards

    • International Fragrance Association (IFRA) Standards and Amendments
    • Cosmetic Ingredient Review (CIR) for residuals and volatile organic compounds (VOCs)
    • EU Regulation (EC) No 1223/2009 for Cosmetic Products
    • ISO 9235:2013 for aromatic raw material origin

    Typical usage ratio

    • 0.3%–1.9% by weight in specialty aroma molecule synthesis; precise dosage set by target odor strength and downstream fractionation

    Downstream process integration

    • Added in early-stage aroma compound assembly, followed by distillation and fractional separation before blending into bulk perfume oil

    Final product types

    • Sulfur-inflected aroma molecule intermediates
    • Perfumery bases for fine fragrance
    • Functional fragrances for consumer products
    • Specialty aroma chemicals for food-compatible flavoring bases

    6. Specialty Fine Chemical Production (Laboratory/Scale-Up Applications)

    Custom synthesis and contract manufacturing labs make targeted use of this raw material in thiocyanation and sulfur introduction for pilot-scale production of screening compounds. This application relies on detailed documentation for batch traceability and supports research projects in specialty chemical discovery, with process controls adapted for safe handling of volatile sulfur derivatives.

    Industry compliance standards

    • OECD Good Laboratory Practice (GLP) for chemical process validation
    • ISO/IEC 17025:2017 for analytical method accreditation
    • REACH Annex XVII for laboratory chemical registration
    • National/local chemical handling permits as required (e.g. EPA TSCA in the USA)

    Typical usage ratio

    • 0.5%–6.0% by mol, varying by scale (gram to multi-kilogram synthesis) and chemical transformation pathway

    Downstream process integration

    • Charged to glass reactor systems at controlled rates during sulfur, cyano, or isothiocyanate functionalization steps

    Final product types

    • Reference standards for analytical testing
    • Sulfur- or cyano-substituted screening compounds
    • Preclinical research intermediates
    • Small-batch specialty reagents for further derivatization
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    Certification & Compliance
    More Introduction

    Butyl Thiocyanate: A Closer Look from a Chemical Manufacturer’s Bench

    Not every day brings a new story in specialty chemicals, but butyl thiocyanate always sparks attention among those who know its true value. In our production line, we treat each batch as more than a formula on paper, watching how ingredients and conditions make subtle differences in the real world. Over years making butyl thiocyanate, patterns jump out—customers ask about purity, consistency, and why sometimes one container ends up better for their purpose than another. People want practical insights, not a sales pitch, and that’s what this commentary aims to do—reflecting the knowledge gained from long hours in the plant, not behind a desk.

    Understanding Butyl Thiocyanate: The Basics Matter

    Butyl thiocyanate stands out in our catalog, not by chance but by practical demand. It’s always been favored for its reactivity in organic synthesis. Chemically, this compound features a butyl group attached to the thiocyanate functional group. Straightforward, yet producing it at scale teaches respect for detail—one wrong step, and the batch picks up traces that no final customer wants. Each time we handle it, there’s a reminder of the responsibility to guarantee not just high purity, but reliability from drum to drum. The standard model we focus on sees extensive use in manufacturing agricultural chemicals, intermediates for pharmaceuticals, and certain flavors and fragrance blends.

    Specifications Grounded in Daily Practice

    Our regular output of butyl thiocyanate hits a purity specification above 98%, which sounds impressive but really comes down to discipline in both raw materials and process control. A fraction of a percent off, and the finishing lab flags the run—nobody likes product recalls or reputational risk. The liquid is clear, with a sharp smell that seasoned technicians spot right away. Density, boiling point, and viscosity might feel like textbook facts until you watch a reaction stall due to small variations. For the people using this chemical, regularity counts; recipes and outcomes depend on getting the same quality every time. That focus on day-to-day performance is why our operators monitor key parameters at every stage, not just at the end.

    Real-World Uses: Beyond a Page in the Catalog

    Manufacturers and R&D labs rely on butyl thiocyanate for more than just its chemical structure. In the field of crop protection, we see its value as a building block for specialty agents, each tailored to specific environmental demands in real planting conditions. In pharmaceuticals, synthesizing certain APIs demands reagents that offer tight control of side reactions. The experience working with customers in both sectors leads to adjustments—sometimes changing input ratios, sometimes altering purification steps, always backing up every claim with actual test results from representative runs, not cherry-picked samples.

    In specialty flavors and fragrances, butyl thiocyanate plays a minor but critical note. The teams formulating exotic fruit essences know the smallest impurity throws off the aroma, turning a premium blend into a reject pile. Making this chemical in-house lets us track which lots went where, so troubleshooting down the chain becomes possible if an issue ever emerges.

    Setting Butyl Thiocyanate Apart from Related Products

    People sometimes ask what makes butyl thiocyanate different from other alkyl thiocyanates or related sulfur chemicals. Drawing comparisons only makes sense if the details are clear. Working in the plant, the first thing that sets it apart is the volatility profile. Butyl thiocyanate boils at a temperature that lets customers handle it using standard equipment. If you go down to methyl or ethyl thiocyanate, volatility adds hazards and extra steps for containment. Go up to octyl or higher, and you run into issues dissolving or reacting at a reasonable pace.

    Solubility patterns also differ. Our butyl thiocyanate dissolves nicely in typical solvents—ether, alcohols—without surprises creeping up during scale-up. Customers switching from other reagents sometimes comment the reactions run cleaner and more predictably, especially in multi-step organic syntheses. The mid-length alkyl chain keeps side product formation in check, avoiding some of the oily residue seen with longer chain variants.

    Olfactory properties matter, too, even if most users never intend to smell the stuff directly. The butyl chain sits in a sweet spot: less penetrating than methyl but more distinct than hexyl or octyl. In flavor and fragrance pipelines, that subtlety helps create dimensional profiles, not overpower the blend. Translating feedback from experienced formulators into tighter in-house quality controls demonstrates how practical input changes operations—not just adherence to a data sheet.

    Manufacturing Perspective: Building Trust Batch by Batch

    On the plant floor, it’s easy to take shortcuts—but in our experience, that always catches up with you. Every batch of butyl thiocyanate reflects the long learning curve: the right agitation, temperature profile, and quenching rates. Early on, we noticed higher-level automation didn’t replace seasoned operators’ judgment. People who have trained their senses to spot subtle changes—color, odor, flow characteristics—catch issues before they snowball. Listening to team feedback led to process tweaks that now form standard practice.

    Getting the product out the door means more than meeting internal targets. End users judge attention to detail in whether shipments arrive with certificates of analysis that actually match what’s in the drum. Transparency matters—customers need confidence, not just marketing promises. Suppliers who hide behind generic claims don’t last in this business. Every inquiry about a specific lot or property draws on our lab books and plant records, not vague generalities. If a variable creeps in, production teams know about it before customers do, thanks to routine sampling at multiple points.

    Practical Differences in Handling and Storage

    Customers often ask how to store and handle butyl thiocyanate compared to other similar molecules. Long-term experience tells us this compound survives well in tightly sealed stainless steel containers under ambient conditions, away from sunlight and strong oxidizers. Unlike lighter thiocyanates, users rarely battle evaporative losses, and the risk of spontaneous decomposition remains low if the environment stays dry and cool.

    Direct exposure to air and moisture can still cause slow hydrolysis, so opening a drum and resealing promptly isn’t just a best practice—it keeps complaints off the service line. Unlike some sulfur chemicals that attack seals and gaskets, butyl thiocyanate leaves most standard equipment intact, saving time and maintenance costs. Teams working in both large- and small-scale operations benefit from that extra headache avoided.

    Quality Challenges and Solutions Learned Over Time

    Manufacturing butyl thiocyanate brings daily reminders of how even small variations affect the downstream. Early on, we encountered problems that forced us to dig deeper. Occasional off-odor complaints led to a full review of raw material storage—turns out small traces of unintended side products sneak in through overlooked contamination. Tightening supplier audits for the base materials cured that issue. We also learned to adjust cooling times gradually, after seeing yield drop in warmer months due to latent heat not fully dissipating before the next reactor cycle.

    Repeated incidents with trace metal contamination taught us to replace old piping and fittings in part of the line. The investment frustrated management, but customer complaints fell to zero and overall throughput increased. Practical fixes—like adding extra filtration before final packaging—proved worth more than any software-driven quality model.

    Our lab teams spend hours every week correlating GC and spectroscopic results with real-world customer feedback. A “clean” chromatogram on paper sometimes fails to capture how a trace alcohol or sulfur impurity ruins a production run for a pharmaceutical client operating under GMP. The solution meant pushing limits of detection and giving R&D an open line of communication with field techs. Changes in the plant now start with practical data, not management fiat. The tight integration between operations and customers sparks faster troubleshooting and better long-term relationships.

    Meeting Regulatory and Safety Demands Without Shortcuts

    Over the past decade, compliance expectations only grow stricter. Producing butyl thiocyanate brings regulatory requirements at every stage. Instead of skating by with minimal documentation, we learned the hard way that gaps in traceability mean lost business or, worse, legal headaches. Every step from raw material receipt to final shipment logs full details in an auditable format.

    In safety, no shortcuts ever work. Direct skin or eye exposure always causes concern, so training takes real time and commitment. Routine drills in the handling bays push response times down and decrease small incidents. Fire risk remains low compared to more flammable solvents, but teams treat every spill as a reportable event—complacency has no place on a chemical line. Knowledge passed from experienced handlers shapes onboarding for new hires, so key lessons stick.

    Adapting to Changing Demands: Lessons from the Front Lines

    Customers adapt strategies based on shifting market and regulatory pressures. Some years see a run on butyl thiocyanate for new crop protection projects, other times, pharmaceutical demand rises with changes in approved processes. Quick shifts challenge both inventory and scheduling but having flexible distillation and purification systems keeps us agile. Over-planning creates waste; under-preparation leaves customers scrambling. Managing those swings takes realism, not marketing optimism.

    New uses appear yearly. Every approach to a cutting-edge application opens fresh questions; one life sciences firm recently reported better intermediate yields switching from an ethyl-based to our butyl thiocyanate—results even they didn’t predict. Being willing to pilot new purification tweaks on request turns experimental success into a regular part of operations, not a one-off.

    Sustainability and Waste Management—No Empty Promises

    Making butyl thiocyanate produces waste, mostly spent solvent and trace byproducts—anyone telling you differently hasn’t run a plant. Years back, we relied on traditional incineration, but pressure from both customers and new regulations forced a reevaluation. Today, waste streams go through solvent reclamation and dedicated separation units. What once left the plant as hazardous residue now re-enters the process at controlled points, cutting disposal bills and environmental risk.

    Solvent emissions also dropped thanks to incremental investment in vapor recovery units. These changes come with up-front costs but become hard to argue against when repeat tests show compliant levels without end-of-pipe fixes. Sharing real waste and sustainability metrics with end users builds long-term trust and lets procurement teams vouch for supplier ethics with facts, not buzzwords.

    Why Butyl Thiocyanate Continues to Matter

    The long perspective from manufacturing butyl thiocyanate teaches patience—small changes ripple all the way down the value chain. Reliable supply keeps entire projects moving, while hiccups cost real money and credibility. Staying focused on measurable outcomes—batch certification, shipment reliability, purity monitoring—matters more than any marketing spin. Each container we fill represents the accumulated hours of practice, second-guessing procedures, responding to feedback, and fixing the details only an on-the-ground team can spot.

    Customers appreciate more than a finished product; knowing where it comes from and what went right or wrong in its making closes the gap from plant to field or lab. That relationship forms the real difference between a manufacturer who owns every step and resellers who never see inside a reactor vessel. Our aim stays clear: ship something better each time, learn from every problem, and make improvements stick. Only time and steady work can build that kind of confidence, one run at a time.

    Looking Ahead: Opportunities and Challenges in Butyl Thiocyanate Production

    Technology never sits still. Advances in process automation, online quality sensors, and feedstock integration promise even higher consistency for butyl thiocyanate. Still, no tool replaces a well-trained team. The interplay between skilled people and reliable technology defines how well each batch turns out. We constantly monitor pilot plant results and leverage feedback from smaller trial runs to refine the main reactors. Tools like advanced chromatographic fingerprinting now let us resolve even trace impurities, giving customers an order of confidence never possible a decade ago.

    Raw material availability sometimes surprises us, especially during global supply swings. Securing diversified sources for precursors shields daily production from upstream hiccups. Learning where to build redundancy sets apart seasoned operations from fly-by-night ventures. Years of record-keeping and adaptive sourcing give us the data to smooth out rough patches and prevent sudden shortages for end users who count on regular shipments.

    Direct Engagement with Partners: Closing the Loop

    Few things beat open dialogue when troubleshooting or improving a process. Regular customer audits, on-site visits, and development partnerships pay off. One major agricultural chemicals group recently collaborated with our site engineers to optimize their synthesis, shaving days off their schedule. Listening to those closest to the application leads to modifications that ripple upstream to our own procedures and sometimes open new market segments entirely.

    Feedback on packaging has helped, too. Transitioning to tamper-evident, leakproof containers began with direct customer complaints about damaged shipments, not a top-down marketing directive. Small changes—extra inner seals, reinforced drums, improved palletizing—now protect the integrity of the product in real-world transport conditions. Operations staff engage with logistics teams regularly, ensuring improvements are grounded in day-to-day realities, not assumptions.

    Final Thoughts: The Value Created in Practice

    Making butyl thiocyanate isn’t glamorous work, but real value comes from day-to-day reliability. Every run reflects countless choices—raw materials, staff training, equipment upkeep, real-time analysis—coming together to deliver a product that fits its purpose. Reliability gives labs confidence to scale experiments, lets agricultural projects move from concept to field, and helps creative perfumers bring new notes to market.

    Manufacturing up close reveals hard lessons about what matters: attention to real feedback, practical solutions over idealized schemes, and an openness to invest time and effort into gradual improvement. That approach means working side by side with partners, not just shipping a commodity. For us, butyl thiocyanate remains both a daily challenge and a quiet point of pride—the accumulation of every batch we’ve run and each step improved along the way.