Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Bromodichloromethane

    • Product Name Bromodichloromethane
    • Alias BDCM
    • Einecs 200-271-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    558371

    Cas Number 75-27-4
    Molecular Formula CHBrCl2
    Molar Mass 163.83 g/mol
    Appearance Colorless to light yellow liquid
    Odor Sweet odor
    Boiling Point 90°C (194°F)
    Melting Point -57°C (-70.6°F)
    Density 1.98 g/cm³ at 20°C
    Solubility In Water Low (4.5 g/L at 25°C)
    Vapor Pressure 48 mmHg at 25°C
    Flash Point 66°C (151°F)
    Refractive Index 1.494 at 20°C

    As an accredited Bromodichloromethane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 500 mL, with secure screw cap; labeled with hazard symbols, chemical name, concentration, and safety precautions.
    Shipping Bromodichloromethane should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled as a hazardous material, and compliant with relevant regulations (DOT, IATA, IMDG). It must be kept upright, away from incompatible substances, and in a cool, well-ventilated area. Proper protective packaging and documentation are required to ensure safe transport.
    Storage Bromodichloromethane should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from sources of ignition and incompatible materials such as strong oxidizing agents. Protect from moisture, sunlight, and heat. Storage should be in a chemical fume hood or a designated flammable chemicals cabinet, clearly labeled, and restricted to trained personnel only.
    Application of Bromodichloromethane

    Applications of Bromodichloromethane in Industrial Manufacturing

    Bromodichloromethane serves essential roles in several established downstream sectors, with each application governed by distinct regulatory and technical requirements. As a dedicated industrial manufacturer, we supply this material for critical process streams, ensuring tight quality control where compliant, consistent, and traceable supply supports exacting customer operations. Below we outline primary application scenarios, including regulatory frameworks, documented usage ratios, integration into customer process flows, and the nature of finished products.

    1. Water Disinfection By-product Research and Control in Municipal Water Treatment

    Many municipal facilities and specialized laboratories use this compound to simulate and analyze halogenated disinfection by-products (DBPs) formed during chlorination or bromination processes. Accurate dosing and monitoring of this compound supports regulatory compliance, process optimization, and incident investigations required by water utilities.

    Industry compliance standards

    • USEPA National Primary Drinking Water Regulations (NPDWR) – Disinfection Byproducts Rule (DBPR)
    • Standard Methods for the Examination of Water and Wastewater (SMEWW 6232B, EPA 551.1, 524.2)
    • ISO 17943 for volatile halogenated hydrocarbons in drinking water
    • Local authority health and environment agency reporting procedures

    Typical usage ratio

    • Generally dosed into test simulations at 2–100 μg/L, depending on the reference scenario—concentration selected to reflect expected by-product formation and regulatory thresholds

    Downstream process integration

    • Added to laboratory-controlled test systems or standard solutions in analytical method validation; spiked into post-chlorination water in pilot plants for DBP profiling

    Final product types

    • Reference water samples for analytical compliance
    • Calibration standards for GC-MS and GC-ECD instruments
    • Data sets for regulatory submissions and plant optimization
    • Quality assurance panels for proficiency testing

    2. Industrial Analytical Calibration Standard Manufacturing

    Producers of pre-formulated calibration and check standards frequently utilize this compound as a component in certified multi-analyte mixtures, supporting quantitative trace analysis of volatile organohalogens in water, soil, and environmental matrices by regulated laboratories.

    Industry compliance standards

    • NIST traceability protocols for reference materials
    • ISO 17034 (General requirements for the competence of reference material producers)
    • ISO/IEC 17025 (Testing and calibration laboratories)
    • USP General Chapter <467> Residual Solvents for pharmaceutical impurities analysis

    Typical usage ratio

    • Composition in the final calibration mix: 0.1–10 mg/L, chosen based on required working range for target analyte quantification

    Downstream process integration

    • Dosed gravimetrically or volumetrically into custom or standardized multicomponent reference mixtures during batch preparation of CRMs and QC kits

    Final product types

    • Certified reference solutions for environmental monitoring
    • Pharmaceutical manufacturing impurity standards
    • Round robin and proficiency scheme test panels
    • Routine laboratory check standard sets

    3. Organic Synthesis Intermediate for Agrochemical Development

    The controlled halogenation properties of this molecule underpin its use as a reagent in the synthesis of diversified intermediates for certain agrochemicals. Specialized fine chemical companies employ this compound during compound-library expansion, structure–activity relationship studies, and for scale-up of halogenated intermediates destined for use in crop protection agent development.

    Industry compliance standards

    • REACH Registration (EU) for intermediate use
    • ISO 9001 certified quality management in chemical synthesis
    • Guideline-conforming batch traceability (OECD, FAO)
    • National hazardous chemical management standards for manufacturing

    Typical usage ratio

    • 5–25% by weight of total halogenating agents; proportion set by the stoichiometry of the target compound and desired degree of halogen insertion

    Downstream process integration

    • Charged into batch or continuous stirred-tank reactors during early-stage halogenation, followed by quenching, separation/purification, and further functionalization work-up

    Final product types

    • Halogenated ring intermediates for herbicide, fungicide, or insecticide synthesis
    • Fine chemical building blocks for R&D screening
    • Reference substances for agrochemical formulation studies

    4. Pharmaceutical R&D: Synthesis Reference and Analytical Impurity Profiling

    This compound is used in pharmaceutical laboratories for impurity profiling, method validation, and reference standard supply related to halogenated impurity classes encountered in various drug substances and excipients. Integration into workflow ensures the accuracy of impurity identification and supports regulatory dossier submissions to agencies.

    Industry compliance standards

    • European Pharmacopoeia (Ph. Eur.) and United States Pharmacopeia (USP) monographs
    • ICH Q3A/B (Impurities in New Drug Substances/Products)
    • GMP (Good Manufacturing Practice) requirements for contamination profiling
    • FDA and EMA submission guidelines for analytical method validation

    Typical usage ratio

    • Typically spiked at 0.1–10 ppm into pharmaceutical matrices for LC/MS or GC/MS impurity method testing; levels based on specific threshold and reporting requirements for regulated impurity control

    Downstream process integration

    • Added to sample batches or working solutions during analytical validation, forced degradation studies, or used to calibrate analytical methods for batch-release and stability testing

    Final product types

    • Analytical impurity profiling reports for regulatory submissions
    • Pharmaceutical reference standard sets for QC labs
    • Validated drug substance/finished dosage form analysis
    • Batch-release supporting documentation

    5. Environmental Monitoring Proficiency Testing and Quality Assessment

    National environmental agencies, contract laboratories, and PT scheme providers require tightly controlled aliquots of this compound to produce test samples for certification programs. These challenge samples allow ongoing verification of laboratory detection skills and instrument performance across a wide geographic area, supporting multi-site regulatory harmonization.

    Industry compliance standards

    • ISO/IEC 17043 (Conformity assessment: proficiency testing requirements)
    • US EPA Proficiency Testing Program standards for DBPs
    • ISO Guide 34 for Reference Material Production (superseded by ISO 17034)
    • National/metropolitan environmental laboratory accreditation rules

    Typical usage ratio

    • Inclusion at 0.5–50 μg/L in proficiency test water, or 0.1–2 mg/kg in solid matrix challenge samples; level varies by performance criteria and detection method requirements

    Downstream process integration

    • Blended into standardized water, soil, or extraction matrices before homogeneity assessment, bottling, and coded distribution to participating laboratories

    Final product types

    • Officially certified proficiency test kits for volatile organic compound analysis
    • Blind control samples for internal/external quality programs
    • Interlab comparison sets for method harmonization
    • Accreditation support materials supplied to regulatory laboratories
    Free Quote

    Competitive Bromodichloromethane prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Bromodichloromethane: Practical Perspectives from Chemical Manufacturing

    Understanding Bromodichloromethane from the Factory Floor

    Every batch that rolls off our production lines embodies decades of plant experience and a long legacy of responding to the changing needs of water treatment operations, laboratories, and researchers. Among a wide range of halomethanes, bromodichloromethane stands out for its unique performance in both controlled environments and demanding real-world scenarios. As manufacturers, we know what it means to deal with the product up close: from raw material sourcing, to hands-on process control, through final inspection at the plant.

    Composition, Quality, and Physical Characteristics

    Chemically, bromodichloromethane (CHBrCl2) consists of a bromine atom, two chlorines, and one central carbon, completed with a hydrogen. This structure gives it a boiling point near 90°C, and density well above water—details that matter as much on the line as in the lab. Our standard model delivers a purity exceeding 99.5%, supported by gas chromatography and wet chemical analysis at each stage. Even a small slip in raw material quality can lead to unwanted haloacetones or extra chlorinated byproducts, so our QA team runs precisely scheduled checks. Color and clarity sometimes reflect those purity standards; transparent, colorless bromodichloromethane signals product that meets expectations.

    Many end-users look for residual water content and stability as key criteria. Through repeated vacuum distillation cycles, water and heavy ends are stripped. We consistently achieve moisture contents below 0.01%, verified by Karl Fischer titration. High-purity batches stay stable under normal storage, resisting acid or base-catalyzed breakdown without significant color or odor development. Unlike some related materials, this one neither turns cloudy on exposure nor forms a stubborn residue in glassware.

    Applications Linked to Practical Experience

    Among halomethanes, bromodichloromethane sees focused use in water analysis, environmental monitoring, and laboratory reference standards. In both municipal water treatment and academic settings, this compound holds value as a calibration standard for trihalomethane (THM) measurements. Since THMs stem from chlorination of drinking water, labs depend on bromodichloromethane for accurate gas chromatography calibration. The margin for analytical error tightens every year because health standards for THM levels face sharper scrutiny.

    Bromodichloromethane sometimes steps into the synthesis of other specialty chemicals, matched by a handful of agricultural or pharmaceutical intermediate applications. From our direct experience, most customers seek out consistent, testable batches as a requirement for regulatory compliance, especially in environmental monitoring programs. The feedback we receive shows most issues arise when sourcing from fragmented channels lacking traceable manufacturing practices, especially for analytical reference use. Many commercial users report headaches sourcing material of this quality, sometimes facing contamination from related byproducts or impure solvent streams in competitor grades.

    Hands-On Differences: Compared to Other Halomethanes

    People often ask how bromodichloromethane compares to close relatives such as chloroform, bromoform, or dichloromethane. Each product serves a different set of users and comes with its own storage quirks, handling demands, and regulatory considerations. We notice that while chloroform tends to dominate solvent use and historical research applications, it comes under tighter regulation due to higher toxicity and documented breakdown into phosgene in air. Bromodichloromethane sits in the center: heavier and less volatile than dichloromethane, less dense than bromoform. This middle ground in volatility and solubility offers a measure of control in lab handling.

    Our customers in the environmental testing field highlight one practical detail: when purchasing bromoform or chloroform, cross-contamination during shipment can cause secondary peaks in analytical tests, interfering with low-level detection. With bromodichloromethane in a high-purity model, that risk drops. To keep cross-contamination low, we segregate production lines, using separate equipment streams and scheduled tank maintenance. Our team spends weeks tracking down even trace signals of extraneous halocarbons—no easy task if tanker changeovers aren’t tightly managed.

    Bromoform, heavier and with a much higher boiling point, sits mostly in niche industrial roles. Dichloromethane, one of the more common lab solvents, evaporates quickly and handles best in ventilated systems. Bromodichloromethane’s comparatively moderate vapor pressure makes it practical for prep work without constant evaporative loss. In our experience, technicians appreciate this: less product wasted, less odor in the plant, and fewer headaches tracing accidental losses in storage.

    Safety, Environmental Control, and Operator Perspectives

    No factory or warehouse wants to manage hazardous incidents. We dedicate full-time staff to chemical safety, because halomethanes create unique challenges—densities higher than air, limited odor, and persistence in water all raise the stakes. Experience tells us that prudent management always beats reactionary cleanups. For bromodichloromethane, tightly closed, corrosion-resistant drums in climate-controlled rooms limit day-to-day risk. Standard PPE and good ventilation stay important, but up-to-date training and regular plant checks form the real backbone. Nobody wants to handle unknowns.

    As a manufacturer, we keep tabs on changing regulations, since bromodichloromethane draws attention for both workplace exposure risks and as a byproduct of chlorinated water. Vent stack emissions, trunk line leaks, and drain runoffs all come under external review, and local governments raise the bar each year. Our plant teams methodically log usage and keep engineered containment protocols in place—real stories exist behind every compliance report. During heat waves, volatile losses spike, so tank monitors and real-time leak detection matter most. In forty-degree heat, a minor oversight magnifies.

    While most industrial chemicals require basic respect, bromodichloromethane brings unique disposal demands. We operate on closed-loop principles: every shipment includes full tracking, each returned drum meets full-rinse verification, and our teams collaborate with certified hazardous waste processors. Experience reducing evaporative drift and accidental discharges helps build long-term trust with local communities. Regulatory agencies respect transparency and documented batch histories, and environmental improvement spends time in plant meetings—never just a check mark.

    Production Realities and Long-Term Product Integrity

    Manufacturing bromodichloromethane at industrial scales cannot cut corners. Sourcing bromine raw material with consistent assay and clean chloride streams matters to every downstream process. We maintain tight relationship with upstream suppliers, vetting new partners based on documented QC and reliability, not just price. Every time we’ve relaxed those standards, remediation cost always outpaced savings. For teams on the shop floor, nothing frustrates like valve fouling from unexpected residues or unburnt carbon.

    Our process train features reactors, fractional columns, and custom filtration units. Each run begins with inline sensors set to flag deviations: temperature, reflux ratio, hydrogen halide remnant levels. Routine maintenance—shutting down units for descaling, re-spiraling gaskets, draining jacket water—takes a full shift, but prevents months-long shutdowns. Long-time operators understand how a few hours’ effort saves a week’s emergency response. Filters and scrubbers see frequent change-outs, because even minor chloride spikes can skew final product color and marketability.

    Storage integrity fits into the big picture. Bromodichloromethane, denser than water and only modestly soluble, stores best in steel drums lined for halocarbon compatibility. We archive batch samples in heat-stable ampules—critical during customer disputes, environmental sampling, or regulatory trending analysis. Even years later, reviewing archived vials has solved claims over lab discrepancies and shipment quality.

    Our teams recognize that chemical business isn’t just about process parameters; it’s about how day-to-day action lines up with outside expectations. Every inspected container, logbook note, and peer review in the plant reflects those realities. While charts and statistics count, the people behind the tanks and gauges know how a well-run shift supports both customers and corporate reputation.

    Challenges and Solutions Seen Over Years of Manufacture

    Out in the field, customers report analytical drift when switching bromodichloromethane suppliers, often blaming instrument calibration, but lab crosschecks usually trace back to inconsistent reference grade. Our solution stays simple: every batch leaves with a certificate from documented, double-checked analysis, and we keep archival control samples for years. We don’t shortcut testing, even if urgent orders pile up. For storage mishaps—condensation in hot climates, accidental mixing during filling—our plant teams run hands-on staff training, so front-line workers recognize warning signs.

    Supply chain strains sometimes disrupt raw material access, especially if geopolitical or weather events hit port facilities. Over decades, we built alternate logistics channels, rotating inventory and tracking lead times closely. In drought years, we reduced process water demand through closed cooling systems, matching corporate sustainability goals without compromising batch consistency. When new labeling guidelines rolled out, our compliance staff overhauled line-side documentation, working hand-in-hand with operations staff so regulatory changes turned into practical work habits.

    Long-term relationships with customers brought valuable feedback—sometimes difficult, always useful. Plant-side dialogue with research chemists exposed new trends in trihalomethane detection, pushing us to raise analytical reporting detail. Field stories about difficult solvents drove us to update drum design, boosting seal tightness and transport durability. Rumblings from warehouse staff about container weights and stackability led to ergonomic improvements. Experience teaches: adaptability pays off during market shifts and regulatory changes, especially in a field where scrutiny keeps building.

    Ongoing Product Stewardship in an Evolving Chemical Market

    Manufacturing bromodichloromethane doesn’t stop at shipping. Field teams and technical support review product performance and pursue continued improvement. We don’t settle for “good enough” when users’ analytical standards evolve. Our R&D group partners with users to optimize packaging and labeling with today’s safety and traceability needs in mind. Batch-to-batch reproducibility stands as a core measure, but so does clean delivery, robust supply, and hassle-free storage.

    Over time, we saw more clients request customized documentation, chain-of-custody records, or split shipment packaging. These details may sound small, but in analytical work, data integrity depends on source consistency. Every reagent and standard affects test results, so trust starts at the source. Out on the loading dock, our logistics department scans drums before loading, fixing issues before they become customer headaches.

    Responsibility for product lifecycle means close attention to both user safety and environmental impact. Bromodichloromethane brings tighter storage, handling, and disposal requirements than mundane chemicals. Regulatory bodies track usage and encourage best practices, so we update plant standards as official expectations shift. Supply performance, accident prevention, and end-user transparency remain ongoing areas of investment. Robust oversight and training will always be critical, both in the plant and among end users.

    Conclusion: Trust Built on Experience

    Bromodichloromethane production, packaging, and delivery represent a long-term commitment to safety, quality, and response. What customers trust, we protect with careful oversight, open channels for feedback, and continuous process review. Teams at every level—from reactor operators to compliance auditors—contribute daily to keeping each batch clean, consistent, and reliable. The plant isn’t just a background detail; it’s where product quality originates and lives. The hands and eyes managing it every day guarantee standards that go far beyond technical data sheets or casual vendor claims.

    As research methods, health standards, and regulatory requirements keep advancing, manufacturers bear real responsibility—not just for chemistry, but for people relying on its safe and reliable application. In the case of bromodichloromethane, experience proves the difference. Chemical delivery isn’t just product moved from place to place, but trust sustained over years. Those lessons earned in process control, supply resilience, and transparency shape everything we do each day.