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HS Code |
320023 |
| Product Name | Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid |
| Cas Number | 208940-32-5 |
| Molecular Formula | C16H23NO4 |
| Molecular Weight | 293.36 |
| Appearance | White to off-white solid |
| Purity | ≥98% |
| Storage Temperature | 2-8°C |
| Optical Purity | Enantiomeric excess (ee) ≥98% |
| Functional Groups | Boc-protected amine, carboxylic acid, phenyl ring |
| Solubility | Soluble in DMSO, methanol |
| Specific Rotation | [α]20/D +30° to +36° (c=1, MeOH) |
| Iupac Name | (S)-3-(tert-Butoxycarbonylamino)-5-phenylpentanoic acid |
| Synonyms | Boc-L-homophenylalanine |
As an accredited Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 1-gram sample of Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid is supplied in a sealed amber glass vial with detailed labeling. |
| Shipping | Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid is shipped in tightly sealed containers under ambient conditions. It is packaged to prevent moisture, heat, and light exposure. Standard chemical shipping protocols are followed, with handling and transport in accordance with regulatory guidelines for non-hazardous laboratory reagents. Safety documentation is included with the shipment. |
| Storage | Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid should be stored in a tightly sealed container, protected from light and moisture. Keep at a temperature of 2-8°C (refrigerator) to maintain stability. Store in a well-ventilated, dry area away from sources of ignition, incompatible materials, and strong acids or bases. Ensure proper labeling and handle under dry conditions to prevent hydrolysis. |
Applications of Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid in Industrial ManufacturingBoc-(S)-3-Amino-5-Phenyl-Pentanoic Acid serves as a highly specialized intermediate in advanced industrial routes, notably within chiral drug synthesis and custom peptide assembly. Our team manufactures this protected α-amino acid exclusively for downstream sectors where its stereochemical integrity and Boc group compatibility are critical for process efficiency and regulatory acceptance. Below, we outline major application scenarios and technical integration details relevant to our direct industrial clients. 1. Chiral Intermediate for Peptidomimetic Pharmaceutical APIsMajor pharmaceutical manufacturers incorporate this compound during multi-step syntheses to introduce specific chiral centers for peptidomimetic APIs targeting CNS, cardiovascular, and oncology indications. The Boc-protected amino acid is coupled at a defined synthetic stage, after which the protecting group is cleaved under controlled conditions to liberate the active amine for subsequent functionalization or final salt formation. Purity and enantiomeric excess are stringently controlled throughout, and only validated sources meeting regional Pharmacopeia requirements can supply this precursor for regulated market submissions. Industry compliance standards
Typical usage ratio
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2. Protected Building Block in Custom Peptide SynthesisBiopharma contract manufacturing organizations (CMOs) and research laboratories utilize Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid in custom peptide syntheses where insertion of a sterically demanding, chiral side chain is required to enhance resistance to enzymatic cleavage. Its protected format ensures integrity during SPPS elongation and can be selectively deprotected for subsequent modifications. Stringent tracking supports peptide batch release for regulated preclinical or diagnostic reagents. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Precursor for Enzyme Inhibitor Research CompoundsSpecialty chemical research companies and university spin-offs use this intermediate as a structural core to develop new enzyme inhibitors, including protease and peptidase antagonists. Its extended phenylated backbone and stereochemistry allow derivatization to structure-activity relationship (SAR) libraries. Reproducible protecting group removal and absence of racemization ensure meaningful activity profiling results and scalable lead compound optimization. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Intermediate in Beta-Amino Acid-Based Polymer SynthesisAdvanced material developers employ this substrate in the synthesis of high-value polymers containing β-amino acids for biomedical or nanomaterial applications. The Boc group safeguards the amine during protected monomer assembly, preventing side reactions as the polymer backbone forms through step-growth or ring-opening polymerization. Process control focuses on achieving defined tacticity and functional end-groups for downstream processing. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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In an industry overflowing with intermediaries and repackagers, true chemical manufacturing means more than just fulfilling orders. Every flask, reactor, and kilo of Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid tells a story about attention to detail and respect for scientific rigor. This compound takes shape in our own facilities, not passed from hand to hand, but shepherded by experienced chemists who know the demands of modern medicinal chemistry and peptide synthesis inside out.
Over years of scale-up and hundreds of production runs, we have seen what undermines a reliable supply: inconsistent conditions, poor documentation, and lack of technical understanding. These are problems that don't show up until a batch doesn't perform during solid-phase synthesis or a customer runs into chiral purity issues mid-project. Our crew learned early that you can’t cut corners and hope for repeatable success, especially with more complex amino acid derivatives like Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid. The distinctive structure—including the protected amino group and the extended, chiral side-chain ending in a phenyl ring—places real demands on every part of the process, from raw material sourcing down to the control and workup strategy for each batch.
This compound doesn’t start in a catalog; it starts in our synthesis plan. Each step, from constructing the pentanoic acid backbone to introducing the (S) stereochemistry and installing the Boc protection, comes out of protocols developed safely within our own labs. We choose every reagent based on purity and compatibility. Chemists with hands-on experience ensure strict attention to stoichiometry, temperature windows, and isolation conditions. We don’t just trust that the product “should” match the literature; our analytical team checks every lot by chiral HPLC, NMR, and mass spectrometry, revealing any racemization or impurity that could compromise downstream applications.
Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid, as we manufacture it, typically reaches customers as a white to off-white crystalline powder. Rigorous drying and solvent removal ensure low residual solvent, and we document impurities to levels most resellers overlook completely. Our standard model covers a wide purity range, but we maintain a high threshold for internal QC: most lots reach 98% or higher by HPLC, and chiral purity sits consistently above 99%. This consistency means reliable coupling performance in automated peptide synthesizers or manual protocols. Controlled particle size and low moisture enable smooth handling—nothing clumps, cakes, or surprises our partners mid-synthesis.
Direct control matters. We respond immediately to process deviations—whether it’s an unexpected IR outlier or a drift in melting point. We solve those in real-time with our QC and process teams working side by side, not through a third-party with no insight into the actual synthesis. These small interventions add up over multiple batches—less batch-to-batch variance, more predictable reactivity, and a supply chain that doesn’t rely on oversold traders or reprocessors.
For medicinal chemists and peptide scientists, the difference is clear when working with this compound. Without visible or detectable racemization, there’s less worry about downstream enantiomeric contamination. Multi-step peptide assembly, particularly solid-phase methods using Fmoc or Boc protection schemes, relies heavily on the reliability of each building block. Even minor contaminants wreak havoc on coupling efficiency and purification work later. Years ago, one of our teams tracked a persistent low-yield problem back to micro-impurities in a single raw material batch—a lesson burned into everyone’s workflow since. That’s why we screen not just for “purity” but for the exact profile of isomers, side-products, or residual protecting groups that bring trouble.
Research never stops, and neither should the quality of foundational intermediates. The demand for chiral amino acid derivatives like Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid keeps growing, not just for peptide drug development, but for new materials, catalyst design, and advanced biological probes. Structure-activity studies need authentic, reproducible starting points—we offer the traceability and transparency that lets teams publish and patent with confidence. In one notable collaboration, we supplied multi-kilogram quantities for a high-throughput screening program, hitting the specification every time because we tracked each critical control point from raw material entry to the final packaged product.
Sourcing direct from the manufacturer brings long-term advantages: reliable lead times, technical dialogue with chemists instead of salespeople, and the chance to request modified specifications or alternate packaging. We answer directly to our customers’ feedback, not to anonymous purchasing nodes. Beyond batch records and certificates of analysis, our team provides full synthetic route disclosure and will discuss possible optimizations if your process requires unusual solvent systems, particle morphologies, or high-throughput automation readiness.
Most intermediaries publish generic specs or copy information from other listings. Years of hands-on production have taught us the tricks that mask real manufacturing detail. We don’t rely on vague claims or inflated values; our typical batch analytical data gets included with every shipment. Product codes mean little compared to validated purity checks, full chiral analysis, and impurity mapping reports—not just a one-page summary, but documents that back up every claim we make.
On occasion, major research organizations have called on us to investigate issues in their own projects traced back to “off-the-shelf” chemicals. It’s not rare to find significant differences among lots sold as “Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid” but repackaged with minimal inspection. Our technical staff keeps detailed batch dossiers and sample retains, so if questions ever arise, we can trace the synthesis history back to raw material origin, review every step of the work-up and analysis, and offer informed, solutions-oriented support.
Trust in a chemical supply doesn’t grow from labels, but from process transparency. We have always tracked and documented each stage of Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid manufacture, beginning with sourcing aromatic precursors from established partners audited for quality and compliance. Our analytical records are kept for years. Key control points—like temperature during Boc protection or solvent ratio during workup—receive extra scrutiny, documented in batch records available for technical review. Our audits consistently meet or exceed the standards set by major multinational pharma groups and regulatory inspections.
Complications in the downstream use of this compound often link back to invisible problems: a trace of racemization from base exposure during synthesis, or a concealed side-chain impurity from incomplete work-up. By handling each run ourselves, and not trusting production to anonymous tolling partners, we can track and eliminate these weak links. Customers who rely on this level of diligence report markedly lower failure rates in their own synthesis and scale-up. Beyond the immediate chemical properties, it’s the disciplined approach that sets direct manufacturers apart.
The real world of research and development rarely fits a rigid model. Pharmaceutical teams and academic groups use Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid under varied protocols, solvent systems, and purification schemes. We make supply decisions based on these user realities. Packing is done in certified clean rooms, with choices from small flask-size to drum quantities, and always with relevant container specifications—because even the best compound can degrade without proper moisture control. We have adjusted particle size on request for teams working at both bench and pilot plant scales, and we keep reserve sample retains for post-shipment tech support.
Because every batch follows meticulous internal SOPs, each shipment represents our ongoing attention to reproducibility. We receive specialized requests from partners working on sterile GMP manufacturing, high-throughput screening, or advanced solid-phase synthesis campaigns. Adjustments for custom solvent compatibility, extended documentation, and tailored certification get handled on the front lines—not shuffled to a back office. This approach keeps feedback cycles tight and problems minimal.
A handful of hard lessons defined the way we operate. Early in our production history, we learned that varying the source of even the simplest raw materials could drastically impact the performance of Boc-protected amino acids downstream. One year, a subtle change in base supplier caused undetectable shifts in enantiomeric excess, only visible when one research partner tracked anomalous coupling yields over several projects. That episode taught us to audit every supplier, validate each incoming lot, and run in-house confirmation for all critical physical constants. Mistakes made once become preventative measures for the future—a culture of continuous improvement that a hands-off distributor simply can’t emulate.
Too many intermediates reach market with incomplete purification, residual solvents beyond the norm, or misleading chiral claims. As manufacturers, we decided early to reject any approach that puts volume before transparency. For customers, the biggest difference is the absence of surprises—no last-minute lot swaps, inconsistent color, or paperwork that fails basic technical checks. Our deliverables match what’s written, because the same technicians who perform the synthesis also write the batch documentation.
Other companies offer this molecule under various trade names and catalog numbers, but direct manufacturing means we own the risk and the responsibility for every shipment. We report not only the standards we meet, but the tests we actually run—optical rotation, detailed impurity checks, and in-process controls that cover more than headline values. Our in-lab support and customer documentation come from hands-on experience, not generic boilerplate.
When project managers and chemistry teams describe their needs, from five grams to five kilos, they expect fast, direct answers to technical questions and rapid turnaround on documentation. We deliver technical support and supply chain assurance in a way that no trading house can match: real-time access to the chemists in charge, not delayed answers from intermediaries. Our feedback loops don’t break down in times of rush or high demand because we set batch priorities and production schedules based on critical project timelines, regulatory deadlines, and seasonal research cycles.
Chemical manufacturing constantly faces new demands. Peptide developers come to us needing extra-pure Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid for automated synthesizer runs, high throughput combinatorial work, or protected intermediates for custom drug targets. Many choose us when they’ve experienced a failure with previous “same name” products sourced from bulk market sellers. In these cases, we go straight to the root: reviewing actual synthesis protocols, checking for compatibility in activation chemistries, and offering batch-specific recommendations—sometimes tweaking protection or drying profiles to fit the newest synthesizer platform or coupling agent.
Longstanding relationships with research institutions and commercial partners allow us to see trends, forecast demand, and maintain stocks—not to speculate on price, but to minimize wait times and keep innovation moving. Our process flexibility—developed from on-the-ground problem-solving over years—means that changes in regulation, performance standards, or user specification trigger immediate internal review and practical adoption, not delays or bureaucracy.
Results on the bench reflect upstream choices. For research chemistry, missing a milestone costs more than the price difference between direct purchase and distributor mark-up. Sourcing Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid from original manufacturers delivers more than a consistent product; it provides insight, adaptability, and shared knowledge developed over hundreds of successful projects. Our experience tells us that every gram delivered echoes investment in countless hours of method optimization, analytical troubleshooting, and customer support unlike anything available through a catalog entry or third-party listing.
As the chemical landscape evolves, and as researchers push into novel areas of peptide engineering and drug discovery, precision and reliability become the true differentiators. Partnerships with credible, accountable manufacturers let teams innovate without constantly checking for hidden risks or unreliable supply. For us, every order is a renewed commitment to that trust.
Supply chains grow more complex each year. Regulatory checks, fraud, market volatility, and technical challenges test manufacturers and users alike. Our approach stays grounded in one idea: responsibility for every gram of Boc-(S)-3-Amino-5-Phenyl-Pentanoic Acid we ship. Investing in our own people, facilities, and analytical technology doesn’t just guarantee better numbers on a certificate; it protects the downstream work that researchers, developers, and production scientists depend on. We see ourselves as co-investors in each project’s success, not just vendors moving inventory.
Being at the manufacturing source means we see—every day—the value of open communication, technical rigor, and a willingness to solve new problems. It’s a philosophy forged in real challenges and refined through the expectation that research will only grow more ambitious with time. Working together, chemist to chemist, we keep pace with those ambitions.