Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Bisabolene

    • Product Name Bisabolene
    • Alias Linderene
    • Einecs 217-206-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    501025

    Name Bisabolene
    Molecularformula C15H24
    Molarmass 204.35 g/mol
    Appearance Colorless to pale yellow liquid
    Boilingpoint 153-156°C at 16 mmHg
    Density 0.876 g/mL at 25°C
    Solubility Insoluble in water, soluble in organic solvents
    Odor Mild, woody, sweet aroma
    Structuretype Sesquiterpene hydrocarbon
    Casnumber 495-61-4
    Isomerism Exists as α-, β-, and γ-bisabolene isomers
    Flashpoint 56°C (closed cup)
    Refractiveindex 1.493-1.496 at 20°C

    As an accredited Bisabolene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Bisabolene is supplied in a 100 mL amber glass bottle, tightly sealed with a screw cap, labeled with safety and handling information.
    Shipping Bisabolene is typically shipped in tightly sealed, chemical-resistant containers to prevent leaks and contamination. It should be stored and transported in a cool, well-ventilated area away from heat, ignition sources, and incompatible substances. Proper hazard labeling and compliance with local, national, and international regulations are essential during shipping.
    Storage Bisabolene should be stored in a cool, dry, and well-ventilated area, away from sources of ignition or heat, as it is flammable. Keep it in tightly sealed, clearly labeled containers made of compatible materials. Store away from oxidizing agents and direct sunlight. Ensure proper grounding and bonding for bulk storage to prevent static discharge. Follow local regulations for chemical storage.
    Application of Bisabolene

    Applications of Bisabolene in Industrial Manufacturing

    Bisabolene, a sesquiterpene hydrocarbon derived from various botanical sources, finds structured and compliant use across several focused industrial sectors. Our manufacturing-grade Bisabolene supports precision formulation and adheres to global industry standards in each application environment. Detailed below are current, active downstream sectors where this raw material serves as a functional input with specific compliance, dosage, and integration requirements.

    1. Fragrance Ingredient for Fine and Functional Perfumes

    Leading fragrance manufacturers incorporate Bisabolene as a specialty base note in both fine fragrances and household odor control formulations. Its molecular structure enables stable aromatic profiles with nuanced spice and herbal characteristics that meet contemporary scent trends. Blenders use Bisabolene during the compound mix phase, as it exhibits excellent solubility with esters and alcohols, supporting reproducible end profile consistency across bulk batches and mass consumer markets.

    Industry compliance standards

    • International Fragrance Association (IFRA) Standards, latest amendments
    • EU Cosmetics Regulation (EC No 1223/2009)
    • Cosmetic Ingredient Review (CIR) listings for safety assessment
    • REACH registration and Safety Data Sheet transparency

    Typical usage ratio

    • 0.1%–2% by total formulation weight; perfumers adjust within this window based on olfactory intensity tests and compatibility with other terpenes

    Downstream process integration

    • Direct addition during perfume compounding, before ethanol dilution and filtration
    • Incorporation into premix for household air freshener concentrates or scented consumer products
    • Perfume fixation and stabilization after high-temperature blend steps

    Final product types

    • Eau de toilette, Eau de parfum, perfume oils
    • Aerosol and solid air fresheners
    • Fragranced cleaning concentrates

    2. Flavoring Intermediate for Food Additive Manufacturing

    Food industry compounders use Bisabolene for specialty flavor notes in botanical extracts and certain processed food additive formulas, mainly where citrus, peppery, or pine nuances are sought. Our Bisabolene is suitable for use after compliance screening for food contact, with batch traceability and residue analysis. Processors introduce Bisabolene during concentrated flavor blend phases, under tightly controlled dosing validated by sensory panels and analytical QA testing.

    Industry compliance standards

    • U.S. Food and Drug Administration (FDA) 21 CFR Part 172.515 (Flavoring Agents and Related Substances)
    • European Commission Regulation (EC) No 1334/2008 on flavorings
    • ISO 22000 Food Safety Management System
    • GRAS (Generally Recognized as Safe) review status

    Typical usage ratio

    • 0.01%–0.05% in finished food additive concentrate; adjusted according to flavor intensity, matrix compatibility, and regulatory maximums

    Downstream process integration

    • Added during compounding of essential oil blends for use in the beverage and spice sectors
    • Dosage validation in pilot runs before full-scale batch production
    • Blended downstream with carrier oils or solvents for microencapsulation or spray-dried powder applications

    Final product types

    • Flavor extracts for confectionery and bakery applications
    • Beverage flavorings for botanically flavored waters and mixers
    • Encapsulated spice additives

    3. Precursor for Bio-Based Polymers and Resins

    Chemical producers utilize Bisabolene as a renewable hydrocarbon feedstock for the synthesis of advanced biopolymers and specialty resins. Its molecular configuration makes it a suitable monomer or modifier in applications targeting sustainable, partially bio-based plastics. Bisabolene enters the reaction network during polymerization, where its integration supports alternative resin formulations under green chemistry protocols and product lifecycle transparency for eco-labeling initiatives.

    Industry compliance standards

    • ISO 14021 Environmental Labels and Declarations – Self-declared environmental claims
    • ASTM D6866 (Bio-based Content Analysis)
    • RoHS Directive (2011/65/EU) for electronic encapsulants
    • REACH chemical safety registration in the EU

    Typical usage ratio

    • 5%–25% by monomer mass in bio-polymerization runs; blend ratios optimized according to target mechanical and physical properties of the finished resin

    Downstream process integration

    • Introduced into the polycondensation or copolymerization stage as a co-monomer or chain modifier
    • Blending with other renewable monomers before extrusion or thermal curing
    • Performance benchmarks and analytical testing for physical durability and end-of-life recyclability

    Final product types

    • Bio-based plastic films and packaging materials
    • Specialty resin binders for paints and coatings
    • Thermoset and thermoplastic composite matrices

    4. Pharmaceutical Intermediate for Anti-inflammatory Actives

    Pharmaceutical producers employ Bisabolene as a synthetic route intermediate in the manufacture of semi-synthetic anti-inflammatory ingredients, notably those modeled after botanical or terpenoid pharmacophores. Process engineers introduce Bisabolene into the intermediate buildout stages under strict GMP conditions, using validated purification and analytical tracking. The material’s consistent isomer ratio and low impurity profile meet key requirements for active pharmaceutical ingredient (API) precursor streams or excipient manufacturing.

    Industry compliance standards

    • International Council for Harmonisation (ICH) Q7 Good Manufacturing Practice for APIs
    • Pharmacopoeia monographs (e.g., USP, Ph. Eur.) referencing related sesquiterpenes
    • FDA DMF (Drug Master File) registration for critical intermediates
    • GMP certification for production and analytical batch records

    Typical usage ratio

    • Variable, typically 1–10 molar equivalents per synthetic step; process teams adjust based on downstream yield and purity requirements of the final API or intermediate

    Downstream process integration

    • Input to semi-synthetic reaction cascades targeting sesquiterpene-based actives
    • Undergoes isomerization, functional group modification, or cyclization
    • Purification and quality control by chromatographic, spectroscopic, and stability studies prior to final formulation

    Final product types

    • Anti-inflammatory pharmaceutical API intermediates
    • Cream/lotion actives for topical OTC medications
    • Input compounds for advanced terpenoid drug discovery pipelines
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    Certification & Compliance
    More Introduction

    Understanding Bisabolene: Proven Performance and Real-World Value

    Why Bisabolene Draws Enthusiastic Attention

    Production at our chemical plant runs every week with an eye for both process stability and innovation. Bisabolene stands out among terpene products. In our experience, customers who have already worked with sesquiterpenes—whether for fragrance, flavor, or specialty blends—keep coming back for Bisabolene. This isn’t just about its pleasant attributes or natural sourcing. The molecule’s three isomeric forms, combined with storied ease of derivatization, hold real weight in practical formulation work. For years, we pursued higher purity distillation processes specifically to meet growing requests from both fine chemicals and large-volume buyers.

    Crafting pure Bisabolene relies on a gentle but careful control of temperature, pressure, and feedstock balance. In our shop, technicians track every batch for optical rotation, color index, and GC purity. Colorless to pale yellow liquid signals a well-processed batch. Some other terpenes, like α-bisabolol or bisabolol oxides, have their own loyal audiences, but Bisabolene brings a different profile. It holds low viscosity and a light woody-balsamic note, with a resilience against oxidation that users in the fragrance industry can trust in both finished products and aging concentrates.

    Model Options and Market Demands

    We produce two core specifications: a natural Bisabolene derived from steam distillation of essential oil feedstock, and a synthetic Bisabolene built through selective catalytic dehydrogenation of pinene sources. Each route leads to a slightly different isomer distribution and subtle performance in final blends, a point every seasoned compounder quickly notices. For those blending for stable scent bases or those targeting high purity intermediates for pharmaceutical synthesis, our highest grade—GC purity consistently above 98%—offers a reliable foundation.

    Routine testing here is not an afterthought. We know how batch distinctions sharpen or dull the aroma in finished scents. Consistency matters far more in industrial runs than in small artisanal batches. In our own lab, repeated trials reinforce that even small changes in byproduct residue, optical clarity, or moisture cause differences in how perfumers rate stability and shelf life. Users of Bisabolene in perfumery call for crystal-clear material. Those supplying cosmetic actives want certified absence of metal contamination. Our engineers spent months optimizing processes to remove those pain points, cutting out residual phenols and trace aldehydes. Vendors outside direct manufacturing lines often chase volume and miss those fine tolerances. We deliver not in hopes of meeting specs, but as a result of knowing the problems faced by our own formulators.

    Application Breadth—From Fragrance to Biofuel

    In forty years running reactors, I have yet to see a terpene with as much flexibility as Bisabolene. Today’s market sees its strongest demand as a base note for woody or amber accords in fragrance. In dilute form, it brings smoothness and depth, softening harsh citrus tops or supporting delicate floral blends. Our customers working in personal care tell us they prefer Bisabolene over simple limonene or pinene derivatives. The reasons are simple—lower skin sensitization risk, a smoother drydown, and almost no interference with other actives. Few other terpenes combine longevity on blotter tests with mildness on skin patches.

    Research in the last decade explored Bisabolene’s capacity for next-generation biofuels. The molecular backbone offers similarities to precursors in diesel-range hydrocarbons. Engineering teams investigating renewable pathways keep coming to us for pilot lots. They need kilogram to ton-scale batches free of sulfur and phosphorus. We devised multi-step vacuum stripping and polishing to remove trace elements, long before this became standard. By supplying lab and pilot plant scale material, we see firsthand which physical traits cause plugging, instability, or off-odors in real-world testing.

    Direct User Experience—Problems and Solutions

    Every seasoned compounder or R&D lab head learns where lesser-quality material causes headaches. Reports often describe clouding in finished oil, or sensitivity in long-term stability. When Bisabolene purity drops or batches are blended from mixed origin feedstocks, fragrances lose brightness within weeks. In the biofuel sector, the presence of high-boiling residue or polymerizable impurities chokes catalyst beds and increases post-treatment costs. In some earlier years, outside suppliers tried to enter markets quickly by cutting Bisabolene with lower cost terpenes. Analytical labs caught the issue, prompting stricter authentication standards. From the start, we committed to straight, uncut product sourced directly from single-feedstock lines.

    For customers scaling up through contract manufacturing, we see frequent confusion about bisabolene’s compatibility. They ask about solvent blending, storage temperature, and shelf life. We do not leave these questions to an FAQ. Our plant ships every order with a full analytical run—GC, moisture, acid value, index of refraction, color and heavy metal screens. We field calls every week for advice on how to avoid oxidation, what packaging grades stop headspace oxygen, and how to blend to avoid haze in cold-filled finished products. Over time, the most robust packaging used in our own plant shifted product quality perception among regular buyers. Poly-lined drums with inert gas blanketing became our standard, driven only by what works best to keep Bisabolene fresh. Some competitors cut corners on this, but results show over several years in the logbook—this attention to detail keeps material as close as possible to its freshly distilled state.

    Comparisons with Other Terpene Products

    Plenty of fragrance houses or ingredient formulators compare Bisabolene to more familiar terpenes, seeking a replacement or alternative. Classic α-bisabolol, also used for its sweet floral notes and anti-inflammatory value, differs in both scent and reactivity. Bisabolene offers a steadier aromatic base, stretching the woody tones longer throughout the drydown, a quality noticeable even to a novice nose. Even after years of use in our own plant, we see a sharper, woodier balsamic note from Bisabolene compared to β-caryophyllene or myrcene, which can flatten quickly in heavy-use formulations.

    Solvent power stands out as another important difference. Some cheaper terpenes bring greasy residues or require more stabilizer. Bisabolene leaves little trace, blending seamlessly into both oil and alcohol-based systems. We field requests from paints, coatings, and lubricants makers wanting a green solvent that avoids regulatory red tape and brings safe handling as an added bonus. Compared with limonene, Bisabolene resists breakdown during repeated thermal cycling. Those working in adhesives prefer its lower volatility, which expands storage and workable open time. Each of these differences is not just theoretical—we see it reflected in fewer batch failures, cleaner equipment turnover, and better acceptance across regulatory checks.

    Our Manufacturing Principles—What Experience Teaches

    We run a plant, not a trading desk, so the focus day to day is on process reliability and failproof controls rather than chasing what might be hot on the spot market. Safety, transparency and traceability matter more than press releases. Our operators, some with ten to twenty years on the job, are empowered to stop production if the feedstock chemistries drift or in-process values suggest risk to quality. This keeps out-of-specification material from ever reaching finished drums or storage. Customers have learned to trust batches that not only meet, but repeat, quality runs time after time. This is not done by accident. Maintenance logs, tank traceability, and digital records tie every batch back to its source and day of production.

    Raw material selection makes the difference. We go direct to growers for essential oil feedstocks where possible, and when synthesizing, we control our own precursor supply chains. The closeness of the relationship lets us schedule deliveries, test incoming lots on the spot, and adapt rapidly should regulatory rules or crop cycles force a shift. Stability checks don’t stop at product release, either. Retain samples under controlled storage conditions and regular post-production testing ensure our technical team can answer any question, even a year after shipment. If regulations shift, or a buyer needs evidence for a new market, these records carry real value.

    Pushing Forward—Ongoing Challenges and Solutions

    Manufacturing at scale brings constant pressure to balance throughput and sustainability. Terpene markets face a particular challenge as both end-user and environmental standards keep ratcheting upward. There’s often tension between growing bio-based demand and the need to control costs. Year after year, we see regulations on VOC content, trace contaminants, and even packaging tighten. We solve problems as they come by investing in solvent recovery, closed-loop systems, and high-precision reactors to cut emissions as well as cost. The move toward more precise, lower energy processes started not as a market play, but because our own utility bills and emissions logs made it a clear business need.

    Some buyers ask about the full lifecycle of Bisabolene. Today, we push the product further with pilot projects in biosynthetic routes, using engineered microbes to ferment precursor materials in tanks right here on site. These approaches promise renewable profiles, but require patient process development. Building out analytical methods for genetically sourced Bisabolene brought unexpected lessons about new impurity profiles. Traditional synthetic lines remain our highest volume, simply because they scale better and keep costs in line, but biotech continues gaining ground. We have open conversations about batch-to-batch traceability so end users know which route matches their requirements.

    Working directly with end-users sharpens our product every year. Feedback from customers—complaints about residue, improvement requests for color or scent, suggestions for better documentation—drive updates in real time. In the early years, we learned the hard way how a minor change in catalyst could half material shelf life. Today, every trial batch faces real scrutiny not just in our lab, but in pilot applications at customer plants. This iron sharpens iron. For anyone comparing material from us with that from third parties, the difference usually shows on the production line within a month. Less downtime, fewer customer complaints, and steadier output keep our operations team focused and motivated.

    Shared Knowledge and Open Dialogue

    We don’t treat Bisabolene as just another commodity to ship around the globe with little context. Instead, every technical data sheet reflects conversations with buyers who tackled new regulatory regimes, switched packaging midstream, or chased a new application nobody thought of five years earlier. Some of our customers work in established perfume labs; others run startup companies pushing for green solvents in niche coatings. Each brings a set of fresh questions. We open our process to scrutiny, offering plant visits, sample retains, and full transparency on storage, logistics, and even waste handling. The best outcomes come from questions asked early and problems addressed while still small. Our business is built on these dialogues, not one-off transactions.

    We keep close professional ties with university researchers, industry groups, and evolving regulatory bodies. A few years ago, that meant being quick to change phthalate content limits or comply with new allergen screening rules. Staff attend industry conferences, contribute analytical findings, and keep an eye on what scientific literature and user forums are saying. All of this shapes our ongoing improvements, keeps training current, and helps ensure nobody gets blindsided by a surprise product recall or market shift. It’s a point of pride that many local and regional competitors see us as the reference standard—because our approach puts reliability above speed or easy volume gain.

    Real-World Benefits—Why Users Stick with Bisabolene

    In the end, the reasons buyers stay with us for Bisabolene are straightforward. Pharmaceutical intermediate suppliers like how clean the chromatograms are, reducing downstream rework or rejection. Perfumers praise its softer, richer drydown and the way it holds up in long shelf-life blends. Cosmetics formulators know their end-products face fewer hurdles for skin compatibility and regulatory listing. Industrial clients tracking solvent use or advanced materials want a product that brings predictable volatility, keeps catalysts from fouling, and doesn’t tack on hidden storage headaches.

    Early adopters who switched from traditional aromatics or low-cost import blends tell us the difference shows in customer satisfaction. Returning buyers cite not only purity or fragrance stability, but responsive service when a shipment needs rerouting or a new market opens. Supporting every major certification—ISO, REACH, and additional market-specific audits—means buyers find fewer regulatory obstacles and costly repackaging steps. None of this happens without clear lines of communication between our production, lab, and client support teams.

    Looking Ahead—What Remains Unmet

    Every factory faces fresh hurdles each year, whether it’s feedstock supply shocks, new international labeling, or a push for greater trace transparency. We see rising demand for green chemistry, but pricing and consistency still decide the winners in most applications. For Bisabolene, our next focus areas include reducing residual solvents even further, expanding bio-based synthesis, and shortening delivery times for export markets without compromising batch integrity on arrival. External pressures—climate events, trade policy swings, or industry consolidations—affect supply chains daily. Trust between supplier and client rests most on an honest account of what’s possible, what’s proven, and what’s still in progress.

    In a market that rewards reliability, substance, and firsthand know-how over marketing, Bisabolene continues earning its place not just for headline features, but by standing up to repeated real-world use. Every delivered drum packs the experience of a team that worked through failed batches, customer complaints, regulatory twists, and growing technical standards. It’s far from a perfect or finished story. Each year, new technologies, tighter rules, and fresh customer insights drive us to dig deeper into both R&D and day-to-day manufacturing. The reward shows each time a buyer runs a test, runs production, and finds Bisabolene performs to expectations—not as a lucky batch, but as a consistent result of how we make it, every time.