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Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane

    • Product Name Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane
    • Alias Chlorhexidine Base
    • Einecs 401-020-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    588650

    Chemical Name Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane
    Molecular Formula C19H26Cl2N2
    Molecular Weight 353.33 g/mol
    Appearance Pale yellow to beige solid
    Melting Point 139-143°C
    Solubility Insoluble in water, soluble in organic solvents
    Purity Typically ≥98%
    Cas Number 83846-86-0
    Density Approx. 1.18 g/cm3
    Synonyms 4,4'-Methylenebis(2-chloro-3,5-diethyl-aniline)
    Storage Conditions Store in a cool, dry place, tightly closed
    Hazard Class Suspected carcinogen, handle with care

    As an accredited Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 kg of Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane is packed in a sealed, labeled, high-density polyethylene (HDPE) bottle.
    Shipping Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane should be shipped in tightly sealed containers, protected from light and moisture. It must be clearly labeled as a chemical substance, and handled according to standard chemical transport regulations. Appropriate hazard and safety documentation must accompany the shipment, ensuring compliance with local and international shipping guidelines.
    Storage Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from direct sunlight and sources of ignition. Keep it separate from strong oxidizers and acids. Ensure the storage area is clearly labeled, with access restricted to trained personnel. Follow all relevant safety regulations and use appropriate personal protective equipment.
    Application of Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane

    Applications of Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane in Industrial Manufacturing

    As a direct manufacturer of Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane, we supply this specialty diamine to various sectors where its chemical structure enables precise molecular design and targeted performance enhancement. Our decades of technical experience support customer-specific processes across each application arena below.

    1. Polyimide Resin Synthesis for Advanced Electronic Films

    Electronic OEMs and resin formulators use this diamine as a key co-monomer in polyimide synthesis, providing high thermal stability and mechanical flexibility for specialized films and circuit substrates. Its ortho-chloro and ethyl substitutions help fine-tune glass transition points and dielectric properties, critical for miniaturized components. Our technical team collaborates with customer R&D for specific imide formulations bound by strict purity and moisture standards.

    Industry compliance standards

    • IPC-4101: Specification for Base Materials for Rigid and Multilayer Printed Boards
    • RoHS (Restriction of Hazardous Substances) Directive
    • UL 94 Flammability Standards
    • ISO 9001:2015 Quality Management for Electronic Materials

    Typical usage ratio

    • Diamine to dianhydride molar ratios: 0.98:1.0 to 1.02:1.0
    • Modified per molecular weight to achieve final imidization degree and Tg target per product spec.

    Downstream process integration

    • Charged directly to reaction kettles during initial polyamic acid synthesis phase
    • Dispersed in high-purity aprotic solvents under N2 atmosphere
    • Solution cast and thermally imidized in staged ovens between 100°C and 350°C

    Final product types

    • Flexible copper-clad laminates (FCCL)
    • Base films for flexible printed circuits
    • Insulating tapes for electronics
    • Polyimide-coated magnet wires

    2. Epoxy Curing Agent for High-Performance Industrial Coatings

    Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane functions as a unique aromatic amine curing agent, yielding coatings with enhanced chemical resistance and long pot life. It produces glossy, abrasion-resistant surfaces on steel and aluminum when mixed with liquid epoxy resins. Industrial customers specify it when formulating coatings that must sustain exposure to chemicals, solvents, or outdoor conditions in oil, chemical, or marine plants.

    Industry compliance standards

    • ASTM D3023: Standard Practice for Sampling Paints and Coatings
    • ISO 12944 Corrosion Protection of Steel Structures by Protective Paint Systems
    • REACH Regulation (EC) No 1907/2006 – SVHC Compliance
    • OSHA 29 CFR 1910.1200: Hazard Communication Standard

    Typical usage ratio

    • Epoxy/amine equivalent ratio: 0.85:1.00 to 1.05:1.00 by equivalent weight
    • Adjusted for desired gel time and film cure rate; excess influences cross-link density

    Downstream process integration

    • Dosed into two-pack epoxy systems during manufacturing or onsite mixing
    • Blended at low shear until homogeneous; degassed to minimize air entrapment
    • Applied as primer and topcoat layers, followed by thermal or ambient cure

    Final product types

    • Protective coatings for pipelines
    • Tank linings
    • Heavy-duty machinery exterior coatings
    • Industrial plant floor sealants

    3. Synthesis of Specialty Polyurea Elastomers

    Industrial elastomer producers adopt this diamine for creating polyurea elastomers with precise flexibility and resistance attributes, particularly for applications exposed to aggressive chemicals. Its bulkiness and electron-donating groups allow for manipulation of hard/soft segment balance, resulting in custom tensile and shore hardness for molding, coatings, or linings in mining and infrastructure projects.

    Industry compliance standards

    • ISO 9001:2015 for Elastomer Production
    • DIN EN ISO 868 – Plastics and ebonite — Determination of indentation hardness by means of a durometer (Shore hardness)
    • ASTM D2240: Standard Test Method for Rubber Property—Durometer Hardness
    • REACH Regulation and downstream GHS labeling

    Typical usage ratio

    • Amine/Isocyanate NCO:NH₂ ratio: 1.00:1.00 to 1.10:1.00 for tailored flexibility or hardness
    • Blended with chain extenders or secondary diamines for specific modulus targets

    Downstream process integration

    • Pumped undiluted or pre-solved into high-pressure mix heads with liquid isocyanates
    • Applied in spray or casting lines for direct formation of elastomeric films or molded parts
    • Rapid cure initiated in-mold or in-situ at 40°C to 80°C depending on end use

    Final product types

    • Spray-applied containment liners
    • Heavy-duty conveyor belt covers
    • Molded vibration dampers
    • Protective coatings for mining hoppers and pipes

    4. Intermediate for Custom Aromatic Polyamide (Aramid) Fibers

    Our material finds critical use as an intermediate monomer in the polymerization of specialty polyamide (aramid) fibers, essential for demanding filtration and personal protective equipment. The controlled substitution pattern imparts targeted chemical and thermal resistance, supporting production of aramid yarns with tuned molecular weights and mechanical profiles as required by filter and garment manufacturers.

    Industry compliance standards

    • ISO 9001:2015 for Fiber Production Plants
    • Oeko-Tex® Standard 100 (for fibers in contact with skin)
    • REACH Regulation (EC) No 1907/2006
    • NIOSH/OSHA standards for workplace safety in fiber spinning and handling

    Typical usage ratio

    • Diamine:dicarboxylic acid (or acid chloride) ratio: 0.99:1.00 to 1.01:1.00 by mol factor
    • Adjusted for molecular weight control and end-group functionality

    Downstream process integration

    • ]Charged into pre-polymer solution at controlled temperatures under inert gas
    • Polycondensation performed in polar aprotic solvents; high vacuum removal of byproducts
    • Fibers spun wet or dry-jet, followed by washing, drawing, and heat-setting at 200–300°C

    Final product types

    • Industrial filtration felt and woven filter belts
    • Cut-resistant gloves
    • Protective apparel for chemical handling
    • Composite reinforcements for specialty gaskets
    Free Quote

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    Certification & Compliance
    More Introduction

    Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane: From Manufacturing Floor to End-Use Innovation

    Introduction: A Commitment to Chemical Quality Starts at the Reactor

    The path to precision begins with the raw materials and equipment, not with glossy brochures. Every batch of Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane that leaves our facility reflects years of direct process improvements, toughened by feedback from real-world applications and decades of dialogue with technical end-users. We have found that careful temperature control, steady agitation, and clean separation steps during synthesis mark the difference between a predictable intermediate and one that surprises downstream chemists. Small improvements in crystallization produce a marked rise in consistency—a fact we have proven time and time again during scale-up, pilot runs, and full production campaigns.

    The Model Behind the Name: Matching Molecular Consistency to Market Demand

    Across the industry, we see many products with similar names, but the final compound tells you which manufacturer stands behind its substance. With Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane, the difference does not stem from marketing. It starts during the preparation of the 4-amino-2-chloro-3,5-diethylphenyl raw material. Our process relies on batch analytics at key stages. Purity for each shipment matches internal benchmarks—those set according to rigorous in-house stability tests and feedback from our partners, not just commodity norms.

    The value of this product comes out clearly during formulation work. The team in quality control sees firsthand how minor impurities—a trace of mono-chlorinated isomer, leftover solvent, or oxidized fragments—can slow a reaction or produce color changes in finished goods. The engineers and chemists talk, and over time, we realized that simply chasing high HPLC area percent is not enough. By adjusting the crystallization and drying phases, we ensure low iron and sulfur contamination, usually less than parts per million. The result is a stable performance profile compared to many third-party trade samples we have received for evaluation.

    What We See in Our Plant: Handling and Processing Features

    Day-to-day experience in the production line shows that Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane arrives and moves as a consistent pale powder, settling evenly in bulk packaging. Flow properties can shift subtly with ambient humidity, so we keep relative humidity below 55% during packaging. By monitoring for clumping and static, we reduce loss and speed up bag-off.

    On the shelf, this compound resists yellowing and clumping when stored in sealed containers. That’s not marketing. It’s the result of controlled drying and a packaging process that starts only after full analytical clearance. We do not release any consignment with active peroxide residues, nor do we risk storage in any container that shows contamination during our weekly audits.

    Where Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane Fits: Downstream Utility

    For many application chemists, this compound serves as an intermediate that supports specialized colorants or extends the molecular diversity possible in custom resin projects. We have seen it enter as a key building block in specialty azo and anthraquinone dyes. The diethyl substitution pattern supports improved solubility in non-polar systems, making formulation work smoother for organic chemists. Product managers at customer sites frequently report fewer filtration cycles needed to reach color acceptance.

    Another area showing increased demand involves custom polymer modification. The secondary and primary amine groups, aided by electron withdrawal of the chlorine, show well-behaved reactivity—offering selectivity in step-growth or chain-polymerization approaches. The robust shelf life means that R&D groups do not fuss with reprocessing batches after months in storage. Our technical service group receives fewer handling-related complaints for this compound than for alternative aryl diamines.

    Understanding the Differences: Standard to Specialty Transition

    Over the years, we have worked with customers who switched away from basic aromatic amines, often products where inexpensive labor and fleeting supply arrangements resulted in lots that ranged from off-white to tan, some with visible particles or inconsistent melting points. In contrast, Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane manufactured at our site falls within a sharp melting point range. Side-by-side with lower grade competitors, this property shortens dissolution times.

    Many technical buyers cite cost as a deciding factor, but product value often emerges over several production runs. By comparing our product in an end-use evaluation, developers found greater color consistency in finished pigment dispersions and lower levels of unwanted byproducts after high-temperature synthesis steps. For those scaling up to multi-tonne campaigns, our product prevented stoppages triggered by unforeseen contamination during batch charging.

    Process Reliability: Lessons from the Shop Floor

    Every step of batch manufacture, from the charging of solvents to the monitored addition of reactants, is backed by chemical knowledge and constant vigilance. At our facility, operators receive regular training. Process control data and analyses go back more than a decade. Blind samples pulled from each lot are tracked, analyzed, and used for process correction if deviation occurs. This vigilance means fewer excursions from target purity—critical in an industry where a single failed run can cause days of lost work downstream.

    Seeing operators process Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane every day, we have firsthand insights into the traits that matter most to those converting it into finished goods: high purity, constant particle size, and minimal batch-to-batch deviation. Each of these stems not from marketing intentions but from hands-on process experience. When an off-spec batch leaves another origin, rework and remediation costs often exceed initial savings, and manufacturers who have tried both approaches come to appreciate steady supply.

    Specification with Purpose: Analytical Rigor vs. Standards on Paper

    Numbers in a specification document say much less than the story written in a lab book after months of trial and analysis. Throughout repeated joint projects, we find that specification must grow from the realities of chemistry and manufacturing, not from the pressure to chase buzzwords. We have aligned our tests not only to purity percentage, but also to metrics our customers notice: reactivity in controlled condensation reactions, freedom from catalytic poisons, and low rates of insoluble residue during processing.

    Routine GC-MS screening confirms the absence of residual monomer, while inductively coupled plasma (ICP) samples come up clean for iron, copper, and sodium—a focus since we learned that trace metals accelerate decomposition or pigment drift in final applications. Loss on drying and sieve analyses also get performed before release, since a few hours of customer time saved recovering active intermediate show up as completed projects month after month. Several partner sites reported cleaner reaction profiles and increased throughput after evaluating our material side-by-side with prior suppliers.

    End-User Experience: Chemistry Touching the Real World

    Lab analysts who assay every sample can quickly differentiate between grades prepared for open-market bulk trade and those designed for robust technical work. Developers crafting new materials want reactants that resist color shift, reliably handle in typical plant settings, and keep storage concerns to a minimum. In the early years, we experienced supply chain interruptions firsthand when over-reliance on brokers led to odd off-spec cases or materials that never matched trial runs. Bringing the full process back in-house gave us tighter documentation, order fulfillment, and the confidence to promise consistency.

    Ongoing feedback from users guides continuous process improvement. Several large-scale partners requested finer particle size distribution to improve dissolution kinetics; our team responded by tweaking milling parameters, eventually installing dust extraction improvements that kept airborne loss controlled while enhancing end-user performance. This direct development is always grounded in bench trials and pilot batches, not just laboratory hypotheses.

    Comparison to Competing Chemistries

    Different aryl diamines may look alike on a safety data sheet, but chemists working on custom pigments or polymers quickly spot disparities. Some competing intermediates use alternate substitution patterns—omitting either the ethyl or chloro groups—and these structural changes shift solubility, reactivity, and thermal stability. During bench-scale optimization, compounds lacking diethyl substitution often display cloudier solutions in organic solvents and slower coupling rates.

    Whereas basic diarylmethanes suffer from oxidative instability, introducing the 4-amino-2-chloro-3,5-diethylphenyl units improves oxidative and thermal resistance. Our records from long-term retention samples underline this—no notable degradation products after twelve months in darkness, in contrast to older samples of unsubstituted analogues, which develop off-odors and color change. This results in less yellowing and more predictable storage for customers with rolling R&D timelines.

    Other suppliers have offered material with more variable moisture pick-up and caking. Reprocessing or additional sieving creates extra expense on the production floor. By closely managing drying and right-sizing internal packaging, we have less breakage and clean unloading, providing a marked advantage for operations teams who value efficiency.

    Moving Forward: Earning Trust through Supply Assurance

    Over the years, customer priorities have shifted between price, availability, and technical grade. Consistency in supply and continuity in product properties often bring users back after market experiments with the lowest bidder. Sharp documentation trails, regular audits, and a team who understands the chemistry from phenol derivatization to final packaging all contribute to reliability—a fact appreciated most when deadlines get tight.

    In our experience, offering real support—fielding calls from technical teams during their late-stage trouble-shooting, collaborating to adjust key parameters, and being willing to shift internal timelines for urgent needs—matters more than promises on standard sheets. Repeat business from specialty chemical houses and dye formulators gives us the feedback needed to hold the line on purity, minimize trace contaminants, and monitor both regulatory and customer-driven shifts in required material characteristics.

    Raising the Bar: Direct Manufacturer Responsibility

    We believe responsibility for chemical integrity starts before any drum leaves our warehouse. Each decision, from ingredient sourcing to change controls and transport, arises from the belief that manufacturers bear the largest influence on end-user success. Decades spent troubleshooting field complaints, conducting joint trials at customer sites, and tracing causes of challenging batch failures have given us the practical reminders that fine details matter far more than boilerplate standards.

    As regulatory scrutiny increases, end-users expect tighter analytical profiles and lower impurity loads, not just on the final product but on every intermediate. Ongoing changes in legislation and shifts in downstream sectors have prompted several tweaks to our analytical protocols. We have introduced regular heavy metal screening, tracked emerging solvent impurities, and provided documentation demonstrating compliance with the latest chemical inventory requirements in key markets.

    Solving Production and Application Hurdles—A Manufacturer’s Perspective

    Not every project runs according to plan. We have worked directly with application chemists and plant managers to resolve unexpected reactivity, color drift, or clogging events linked to aryl diamine intermediates. Our approach always focuses on identifying root causes—whether a sub-batch arrived with excess moisture, mill fines that slowed dissolution, or a buildup of an oxidized impurity. In each case, our team reproduces the event, conducts targeted analytics, and iterates either the synthesis, purification, or logistics to solve the root problem. This direct feedback ensures that the same batch issues rarely repeat.

    For downstream formulators facing color inconsistencies or variable shelf-life, we have assisted by providing alternate particle sizing, guidance on best storage practices, and custom packaging options that guard against humidity swings. Several customers reported measurable increases in yield per batch following process adjustments based on our recommendations. These solutions grew from lessons on our line—failures corrected, new standards set—and direct reporting from users, never from generic assumptions or speculative theory.

    Looking Ahead: Partnership Based on Real-World Experience

    Chemical performance does not pivot solely on molecular diagrams; it grows from relationships between chemists, operators, and users whose success rides on steady intermediates. Our ongoing investments in better reactant sourcing, operator training, and end-to-end process control reflect a long-term commitment to those who rely on Bis(4-Amino-2-Chloro-3,5-Diethylphenyl)Methane. Our company’s daily life is spent in the plant, not in promotional copywriting. The lessons we have learned from hands-on production, scale-up challenges, and close work with global partners shape each improvement.

    Firms looking for a supplier with real manufacturing roots often visit our facility, exam our logbooks, and test batch samples with their R&D teams. The real-world understanding we bring to every drum, sack, and analysis takes time to build. Each story, every solution, and the trust that emerges result from steady work both at our plant and at our partners’ sites. That effort, and the spirit of collaboration that goes with it, marks the difference between off-the-shelf commodity and genuine manufacturing leadership in specialty chemicals.