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Benzyl-Furan-2-Ylmethyl-Amine

    • Product Name Benzyl-Furan-2-Ylmethyl-Amine
    • Alias BF2MA
    • Einecs 700-922-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    447342

    Iupac Name N-benzyl-1-(furan-2-yl)methanamine
    Molecular Formula C12H13NO
    Molar Mass 187.24 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point Estimated 287-288°C
    Density Approx. 1.08 g/cm3
    Solubility In Water Slightly soluble
    Functional Groups Amine, Benzyl, Furan
    Smiles c1ccc(cc1)CNCC2=CC=CO2
    Inchi InChI=1S/C12H13NO/c1-2-4-9(5-3-1)8-13-10-11-6-7-14-12-11/h1-7,12-13H,8H2

    As an accredited Benzyl-Furan-2-Ylmethyl-Amine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams Benzyl-Furan-2-Ylmethyl-Amine, tightly sealed with screw cap, labeled with hazard warnings and handling instructions.
    Shipping Benzyl-Furan-2-Ylmethyl-Amine is shipped in sealed, chemically-resistant containers to prevent contamination and degradation. The package is clearly labeled as a chemical substance and handled according to regulations for safe transport. It is shipped via ground or air, with documentation and hazard precautions as required by local and international guidelines.
    Storage Benzyl-Furan-2-Ylmethyl-Amine should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as oxidizers and acids. Protect from direct sunlight and moisture. Ensure proper labeling, and keep the container in a chemical storage cabinet, preferably under an inert atmosphere or nitrogen if sensitive to air.
    Application of Benzyl-Furan-2-Ylmethyl-Amine

    Applications of Benzyl-Furan-2-Ylmethyl-Amine in Industrial Manufacturing

    Benzyl-Furan-2-Ylmethyl-Amine serves as a specialty intermediate with pivotal roles in fine chemical synthesis, specifically in regulated sectors that demand well-defined purity, consistent chemical reactivity, and traceable production records. Below we outline established industrial applications based on actual downstream manufacturing practices.

    1. Pharmaceutical Active Ingredient Synthesis

    Pharmaceutical manufacturers incorporate this amine derivative as a critical building block in the multi-step synthesis of select heterocyclic drug molecules, taking advantage of its stable furan and amine functionalities to facilitate regioselective substitutions and carbon–nitrogen bond formations. Process chemists typically introduce it during the mid-stage assembly of active pharmaceutical ingredients (APIs) where controlled reactivity and minimized impurity profiles are crucial for regulatory compliance and batch reproducibility. Its inclusion supports route optimization, enhancing yields while complying with API impurity limits and documentation mandates.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia API Monographs
    • 21 CFR 210/211 U.S. FDA cGMP Regulations

    Typical usage ratio

    • 0.2–2.5 molar equivalents, adjusted by stoichiometry relevant to each target API's synthetic pathway and stage-yield optimization during process scale-up

    Downstream process integration

    • Introduced during second- or third-step reaction sequences in semi-batch reactor systems; frequently isolated as an intermediate or carried through in situ to subsequent condensation or ring-closure reactions

    Final product types

    • Antiviral and antibacterial API intermediates
    • Psychoactive pharmaceutical actives under development pipelines
    • Custom heterocyclic drug scaffolds for contract research organizations (CROs)
    • Chemical reference material standards for pharmaceutical QC laboratories

    2. Agrochemical Active Compound Synthesis

    Producers of advanced crop protection chemicals employ Benzyl-Furan-2-Ylmethyl-Amine in the assembly of novel fungicidal and insecticidal agents. Its molecular structure supports efficient introduction of both oxygen- and nitrogen-containing moieties in agrochemical actives, facilitating downstream chlorination or sulfonation steps. Process engineers rely on its well-characterized reactivity and minimal side-reactions, reducing waste profiles and streamlining purification operations in early-phase product scale-up.

    Industry compliance standards

    • FAO/WHO Technical Guidelines for Pesticide Specifications
    • ISO 17025 Laboratory Certification for Agrochemical Analysis
    • REACH Registration, Evaluation, Authorisation and Restriction of Chemicals (EU)
    • EPA FIFRA Registration for Pesticide Active Ingredient Sourcing

    Typical usage ratio

    • 0.8–1.8 molar equivalents, tuned for conversion efficiency and reaction selectivity during the formation of target agro active intermediates

    Downstream process integration

    • Added to wearable jacketed batch reactors during stepwise aromatic substitution processes; typically used prior to final heterocycle ring closure or before methylation/halogenation functionalization

    Final product types

    • Furan-based fungicide and insecticide technical concentrates
    • Herbicide intermediate key starting materials
    • Prototype pesticide actives for pilot field trials
    • Stability standards for agricultural QC evaluation

    3. High-Performance Polymer Modifier Synthesis

    High-performance polymer producers select this specialty amine to introduce furan-functional pendant groups that enhance crosslink density, solvent resistance, and tailored thermal profiles in engineered resin formulations. R&D teams value its predictable amination kinetics during post-polymerization modification, reliably delivering end-use polymers with distinct compositional features for demanding industrial and automotive components. It enters as a functionalizing agent in dedicated modification lines, supporting tailored molecular design without introducing unregulated residual monomers.

    Industry compliance standards

    • ISO 9001:2015 for Quality Assurance of Industrial Polymers
    • REACH Annex XVII compliance for polymer additives in Europe
    • UL 94 Flammability Standards for Plastics (where applicable)
    • Automotive OEM Quality System Requirements (e.g., IATF 16949:2016)

    Typical usage ratio

    • 0.5–3.0 parts per hundred resin (phr), with precise loading determined through thermal and solvent resistance optimization trials for each polymer system

    Downstream process integration

    • Fed into dedicated functionalization reactors for grafting or end-group modification; batch- or semi-continuous systems used under controlled temperature/pH to secure uniform incorporation

    Final product types

    • Heat-resistant polyamide and polyimide resins
    • Furan-functional thermoset adhesives and coatings
    • Automotive under-the-hood molded plastics
    • High-performance composite prepregs for aerospace subcomponents

    4. Specialty Fragrance and Flavor Intermediate Production

    Within the specialty chemical sector addressing the flavors and fragrances market, our material functions as a route-defining intermediate for finely-tuned furan-based scent and taste molecules. This role demands careful dose control to meet food- and cosmetic-grade purity requirements, with the amine group facilitating controlled derivatization and cyclization to create unique aroma-active compounds. Manufacturing facilities implement robust purification and in-process analytical controls to comply with consumer safety expectations.

    Industry compliance standards

    • IFRA Code of Practice (International Fragrance Association)
    • FEMA GRAS (Flavor and Extract Manufacturers Association)
    • 21 CFR Part 172 – Food Additives Permitted for Direct Addition to Food for Human Consumption (USA)
    • ISO 22716:2007 Cosmetic GMP Guidelines

    Typical usage ratio

    • 0.1–0.6% by weight in precursor batches, rationalized by downstream yield requirements and purity constraints in the final aroma ingredient

    Downstream process integration

    • Employed in staged or one-pot syntheses for aldehyde, ketone, or ether derivatives; often incorporated prior to final refining and chromatographic separation

    Final product types

    • Bespoke furan-derived fragrance bases for fine perfumery
    • Flavor contributor intermediates for processed foods
    • Cosmetic-grade scent compounds for personal care applications
    • Analytical flavor standards for regulatory submissions

    5. Advanced Chemical Research and Custom Synthesis Services

    Contract development and custom synthesis facilities utilize this amine compound to construct custom heterocyclic frameworks, supporting discovery chemistry and method validation in both academic and industrial contexts. Its amine–furan framework opens access to a broad array of cyclization and coupling chemistries, enabling creation of molecular scaffolds not otherwise accessible through legacy intermediates. Research chemists benefit from its well-documented batch consistency, facilitating scale-bridging from milligram to multi-kilogram quantities under stringent documentation and audit conditions.

    Industry compliance standards

    • GLP (Good Laboratory Practice) for regulated research projects
    • ISO/IEC 17025:2017 for laboratory competence and calibration
    • Client-specific validated synthetic protocols
    • Full Chain-of-Custody Documentation & Certificate of Analysis for every batch

    Typical usage ratio

    • Varies from 0.5–5.0 mmol per reaction, adjusted based on project scope, target molecule complexity, and intended scale for route scouting or method optimization

    Downstream process integration

    • Introduced as a core amine in custom stepwise synthesis projects, typically as the limiting reactant in early- or mid-stage coupling reactions; preparation often followed by direct transition to hydrogenation, oxidation, or cross-coupling without intermediate isolation

    Final product types

    • Specialty heterocycle reference materials
    • Lead compound libraries for drug discovery screens
    • Novel catalyst ligands for process development
    • Patented intermediates for academic and industrial R&D
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    Certification & Compliance
    More Introduction

    Product Insight: Benzyl-Furan-2-Ylmethyl-Amine from a Manufacturer’s Perspective

    Understanding Benzyl-Furan-2-Ylmethyl-Amine and Its Value to Chemical Development

    Benzyl-Furan-2-Ylmethyl-Amine, recognized here in our facility by its model code BF2YMA, stands as a product of thoughtful design and reliable chemical synthesis. Our team has handled the transformation and purification of this compound through years of scaled experience and repeated adjustments aimed at real-world processes. We prioritize both purity and reproducibility, not just for the satisfaction of analytical specifications, but because end-users notice the difference in consistent batch behavior. In organic synthesis and pharmaceutical research, such consistency underpins safe development and smooth project timelines.

    Production Process—Craftsmanship Beyond the Surface

    Lab-to-plant knowledge flows freely here. Every batch of Benzyl-Furan-2-Ylmethyl-Amine produced in our reactors comes from a synthesis route built for scale, but checked for granularity. Starting from benzyl halides and furan derivatives, our skilled operators control reaction conditions to keep side-reactions in check, adjusting not just temperatures and solvents but also stirring patterns and addition rates. Finished material runs through isolation and purification steps developed onsite—tight control over crystallization means solid yield with minimal contaminants. Our lab continuously pulls samples, ensuring the target compound matches reported identity and meets trace impurity thresholds. Analytical teams work with HPLC, GC-MS, and NMR for every release—not as a checkbox but as a checkpoint in our own sense of pride.

    Why Technical Purity and Traceability Matter

    Operators here remember the days before automated logs and barcoding. As our output grew and more clients demanded traceable records, it became clear that tracking each step pays off. We document everything: reagents’ origins, batch conditions, operator signatures, and even nonconformities. This practice not only aligns with regulatory guidance; it means researchers and buyers trust what’s on the label. Unmatched purity, whether above 98% or pushing the boundaries at 99.5%, impacts downstream experiments in R&D and production. A fraction of impurity, if left unchecked, can stall weeks of research. We learned this from pharma partners, and once you see a project delayed by uncontrolled byproducts, you respect the need for ongoing vigilance at every step.

    Industry Experience Shaping Our Approach

    We didn’t settle for textbook methods here. Scale-up brings its set of lessons—lab-scale successes can fail under reactor conditions, pressure limits, or solvent costs. After years of scaling aromatic amines and furan chemistry, we invested in filtration setups effective against both fine particulates and oily residues. Buffer tanks and cold traps maintain environmental control so operators stay safe and surrounding systems remain uncontaminated. The specific physical profile—colorless to light yellow crystalline solid—signals to us that the synthesis has run smoothly; any drop in appearance quality triggers a hold and investigation. Consistency in the physical lot is as important as GC trace lines. Details such as melting point and moisture content are checked batch by batch, not as a favor, but a requirement learned from hard-won experience.

    Applications—Meeting Real User Demands

    Benzyl-Furan-2-Ylmethyl-Amine serves a strong role in medicinal chemistry, agrochemical R&D, and certain specialty materials. Chemists look to this molecule for its reactivity at the amine and furan sites, opening routes to further functionalization. Its structure encourages catalytic cross-coupling reactions, and users in pharmaceutical labs employ it as a building block for heterocyclic scaffolds. Our clients frequently modify this core in lead-optimization campaigns, leveraging the selective reactivity imparted by its benzyl and furan groups. In some projects, it helps researchers rapidly expand chemical libraries—speeding up screening and hit validation.

    Academic groups order modest amounts for mechanistic explorations, while process chemists require kilogram lots as campaigns progress from milligrams to pilot scale. Agrochemical companies incorporate it into candidate compounds seeking pest resistance or growth regulation effects. We recognize that material supplied for early-stage research often returns as repeat or volume demands—long-term relationships rely on dependability, more than one-off offers. Direct communication with our manufacturing team gives buyers an avenue to discuss performance in their specific environments, an advantage rarely found when trading through resellers or brokers.

    Comparison with Structurally Similar Chemicals

    Many clients approach us considering analogs—N-benzyl amines and furan-based amines vary in both cost and activity. Through years of direct feedback, we noticed that the introduction of both the benzyl and furan substituents in BF2YMA uniquely tunes its electronic and steric behavior. Simple benzylamines lack the same versatility for subsequent reactions on the aromatic furan ring. Furanmethylamines, without the benzyl, lose some of their compatibility in certain reductive aminations or coupling steps. This combined framework enables more reliable downstream transformations.

    Our manufacturing team handles related analogs and has compared reactivity head-to-head: in hydrogenation, substituted furans can sometimes give unpredictable side-products—our process mitigates this with attention to catalyst loading and bydesign of work-up conditions. With BF2YMA, chemists find an easier time introducing electrophiles at the furan ring without increased risk of overalkylation at nitrogen. The thorough process validation we carry out brings subtle, but important, performance assurances. Process chemists mention cleaner reaction profiles and easier purifications—claims we verify with analytics before shipping any lot out the door.

    Physical Properties—Not Just Specifications, but Practical Benefits

    From production, we’ve seen that Benzyl-Furan-2-Ylmethyl-Amine’s relatively low melting point and solubility features influence both ease of handling and downstream formulation. Some customers ask for specific particle size distributions; we maintain flexibility in our milling and sieving lines to generate customized morphologies. Attention to these details means fewer issues with dusting, bridging, or filtration. The team avoids generic statements about “free-flowing” powders and instead consults with industrial users about what really works in their reactors or blenders. Moisture uptake or caking can sneak up on a batch, especially during humid months. From storage to filling, operator protocol focuses on dry transfer and nitrogen blankets when needed. Material leaving our plant stays in sealed, labeled, and humidity-monitored containers—something developed after learning from less-than-ideal trial runs in earlier years.

    Practical handling matters more than any catalog can summarize. Benzyl-Furan-2-Ylmethyl-Amine arrives as a clear, manageable solid with a subtle odor—reminding users that quality checks begin with the senses. Our crew has received stories from chemists delighted by how quickly BF2YMA dissolves in most common polar organic solvents. We have established guidelines for the best solvents, posting regular updates whenever longer-term storage or shipping brings new trends in stability data.

    Consistency—Achieving the Same Outcome, Batch After Batch

    Industrial buyers want repeatable results more than anything—especially in scale-up or pilot plant trials. Over the course of producing Benzyl-Furan-2-Ylmethyl-Amine for hundreds of campaigns, we have maintained detailed records correlating impurities to reaction conditions, environment, and raw materials. Successful long-term partnerships stem not just from executing synthetic steps, but from owning and documenting every variable. Auditors and regulatory reviewers often walk through our plant to verify reporting systems, but we invite this as part of our own process improvement and pride.

    Daily checklists minimize risk—raw materials run through identity checks, and operators monitor not just yield but also process efficiency. Unusual odors or color changes prompt immediate operator investigation, and our team shares insights across shifts. Traceability goes beyond batch numbers: each kilogram has a clear lineage back to the original synthesis run, reagents received, and even climate conditions during processing. Lessons from early missteps—unscheduled shutdowns, batch failures—taught us to value procedural discipline as much as innovation. Consistency builds reliability which, in turn, reinforces customer confidence.

    Addressing Challenges from End-Use Feedback

    Sometimes, downstream users report unexpected reactivity or minor side products—real-world chemistry doesn’t always match reference procedures. Our technical support staff and shift leaders keep lines open, treating feedback as constructive data. Adjustments have included tuning how much base or acid to use in quenching, controlling temperature ramps, or fine-tuning the order of raw material addition. This two-way learning loop benefits all involved: improved batches, less waste, and more satisfied researchers.

    Occasionally, fresh data from beta users challenges our working assumptions on optimal storage or transport. Tropical climates, for example, tested our classic drum liners—prompting an upgrade to moisture-proof, shipping-tested packaging. We now work closely with users expecting repack operations or sensitive transfers, sharing best practices so the batch quality extends beyond our gates.

    Storage and Logistics—Lessons Learned by Doing

    As a manufacturer, we understand shipping doesn’t always go as planned. Delays on the road, warehouse temperature spikes, or customs bottlenecks impact chemical stability. Years ago, a summer shipment experienced heat that tested our assumptions about thermal stability; the resulting investigation brought real improvements. We now monitor not just analytical certificates but also the physical “life story” of every bulk drum. Real-time temperature loggers, double seals, desiccant packs, and clear labeling show that manufactured quality is only as good as the storage and logistics that follow.

    We coach receiving sites to store Benzyl-Furan-2-Ylmethyl-Amine away from humidity, heat, and sunlight. The chemical shows robust shelf life in secure, moderate climates, but a few weeks in the wrong environment can invite discoloration or unwanted reactions. Maintaining integrity from loading dock to installation is not an afterthought—it comes from commitment throughout the supply chain.

    Direct Access and Clear Communication Make the Difference

    Many users mention how frustrating it can be to get answers on material status, delays, or unexpected handling quirks. Our structure means actual manufacturing teams respond to technical queries, and engineers discuss order flexibility when timelines change. This is more than a sales promise. It reflects our belief that open dialogue builds trust across years, not just months. Clients have said it is rare to reach a technical decision-maker directly, especially at short notice. We provide this because the people making and testing the batches see firsthand both opportunities and risks—nothing compares to the perspective gained through manufacturing experience.

    Tracking orders, understanding changes, and sharing technical findings all come from close interaction between our shop floor and downstream users. This reduces miscommunication, sets expectations, and demonstrates that each batch is more than anonymous material on a shelf.

    Continuous Improvement—The Manufacturer’s Pledge

    Regulatory landscapes, environmental controls, and customer expectations never hold still. Adaptability comes from repeated investment—new filtration gear, improved analytical methods, faster response time. Every new specification or comment on a certificate finds its way into process updates. Years on the factory floor have taught us to reevaluate not just what’s measured but how questions are asked. We have swapped in greener solvents, tested waste-minimization setups, and invested in energy-recovery in the plant. Improving Benzyl-Furan-2-Ylmethyl-Amine production doesn’t stop at yields: it extends to the footprint our chemistry leaves behind and the clarity of data provided to buyers.

    Future Directions—What’s Changing, What Stays the Same

    Chemical manufacturing will keep evolving, driven by regulatory shifts, advances in green chemistry, and smarter analytics. For Benzyl-Furan-2-Ylmethyl-Amine, development pipelines continue adding new application requests—options in advanced material science, targeted drug design, or sustainable agrochemicals emerge from both client successes and our internal R&D. The persistent principle guiding us stays the same: provide solid, verifiable product supported by direct access to the experience and expertise of a manufacturing staff that knows the full process arc—sourcing all the way through customer application. Over time, trust earned from performance speaks louder than any technical literature or sales page. That’s how we judge success: by the real results and strong relationships forged with every batch produced.