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Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate

    • Product Name Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate
    • Alias BPS
    • Einecs 243-003-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    523552

    Name Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate
    Cas Number 85264-75-3
    Molecular Formula C24H14N2Na2O6S2·3H2O
    Molecular Weight 656.56 g/mol
    Appearance Yellow to brown powder
    Solubility Soluble in water
    Melting Point Decomposes before melting
    Purity Typically >98%
    Storage Temperature 2-8°C
    Synonyms 4,7-Diphenyl-1,10-phenanthroline-2,9-disulfonic acid disodium salt trihydrate
    Applications Colorimetric determination of iron
    Ph 1 Solution Around 6.0-7.0
    Ec Number 286-024-8

    As an accredited Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g supplied in a sealed, amber glass bottle with tamper-evident cap. Clearly labeled with chemical name, formula, and hazard warnings.
    Shipping Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate is shipped in tightly sealed containers to prevent moisture and contamination. It is typically packed according to chemical safety regulations, labeled appropriately, and shipped under ambient conditions. Hazard labeling and documentation ensure compliance with transport regulations for laboratory chemicals. Handle with care during transit.
    Storage Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate should be stored in a tightly sealed container, protected from light and moisture. Keep it at room temperature (15–25°C) in a cool, dry, well-ventilated area. Avoid contact with incompatible substances such as strong oxidizers. Store away from heat sources, acids, and bases, ensuring the storage area is clearly labeled and chemical safety procedures are observed.
    Application of Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate

    Applications of Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate in Industrial Manufacturing

    As a primary manufacturer of Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate, we supply this high-purity reagent for integration into specialized industrial processing lines. Its specificity for iron(II) detection and compatibility with automated analysis systems makes it necessary for several downstream sectors with rigorous compliance requirements.

    1. Water Analysis Reagent Formulation

    This chemical functions as a core chromogenic agent for iron(II) analysis in water quality laboratories. Automated online analyzers use it to monitor municipal and industrial effluents for ferrous ions. The sulfonated ligand’s selectivity under acidic conditions produces a stable colored complex, facilitating photometric detection. Customers in water treatment operate within strictly controlled environments due to regulatory discharge limits. Formulators blend it with buffer solutions and stabilizers, paying close attention to pH adjustment to maximize responsiveness and precision in high-throughput testing.

    Industry compliance standards

    • US EPA Method 315B (Iron in Water by Phenanthroline)
    • ISO 6332:1988 (Water Quality — Determination of Iron — Spectrometric Method)
    • EN ISO/IEC 17025 laboratory accreditation
    • Standard Methods for the Examination of Water and Wastewater, 23rd Edition, Method 3500-Fe B

    Typical usage ratio

    • 0.2–1.0 g/L in analytical reagent concentrates, adjusted for the specific colorimetric range and detection limits required by the analyzer model

    Downstream process integration

    • Direct addition during liquid reagent concentrate preparation
    • Stirring and homogenization with other color reagents
    • Final adjustment of pH before dispensing into individual analyzer cartridges or test kits
    • Quality control for batch consistency and photometric response

    Final product types

    • Photometric iron(II) test kits for water analysis
    • Laboratory-grade liquid reagents for automatic wet-chemistry analyzers
    • Pre-filled cuvettes for wastewater screening
    • Modular reagent bags for online water quality monitoring units

    2. Clinical Chemistry Diagnostics

    Hospitals and clinical laboratories use Bathophenanthrolinedisulfonic Acid salts in colorimetric methods to identify trace iron levels in blood serum. Analytical kit manufacturers formulate ready-to-use reagent vials for automated diagnostic instruments. Strict in-process control ensures reagents exhibit batch-to-batch lot stability and consistent reaction times, enabling accurate patient diagnostics. Material purity, stability in storage, and minimized contamination risk align with health authority standards and laboratory validation protocols.

    Industry compliance standards

    • CLSI C40-A2 (Iron, Total and Unsaturated Iron-Binding Capacity in Serum)
    • IVD CE-marking under EU Regulation (EU) 2017/746
    • US FDA 21 CFR 820 QSR for medical devices
    • ISO 13485:2016 for medical laboratory reagents manufacturing

    Typical usage ratio

    • 0.18–0.45 g/L in final color reagent solutions, altered based on analyzer calibration and target sensitivity

    Downstream process integration

    • Dissolution and buffer mixing in controlled cleanroom environments
    • Filtration and sterile filling into IVD-grade vials
    • Inclusion in multi-component diagnostic panels with strict traceability
    • QC sampling for color development under assay conditions

    Final product types

    • Serum iron determination kits
    • Automated clinical chemistry analyzer cartridges
    • Blood iron diagnostic test strips
    • Hospitals’ in-house standard reference reagents

    3. Pharmaceutical API Quality Control

    Pharmaceutical analytical labs use this material in validated test protocols for detecting trace iron contamination in drug substances and excipients. Its high water solubility and well-defined complexation properties meet GMP lab needs for robust impurity profiling. Analysts prepare bespoke reagent solutions to detect Fe(II) in cleanroom environments, with strict adherence to pharmacopoeial procedures and batch documentation for regulatory submissions. Material traceability and absence of interfering impurities support routine raw material release and in-process control testing as part of the global pharmaceutical supply chain.

    Industry compliance standards

    • USP General Chapter <232> and Chapter <233> (Elemental Impurities Procedures)
    • European Pharmacopoeia (Ph. Eur.) 2.4.23 (Iron Detection)
    • Japanese Pharmacopoeia, General Tests for Iron
    • ICH Q7 GMP for Active Pharmaceutical Ingredients

    Typical usage ratio

    • 0.1–0.4 g/L in custom-developed colorimetric detection reagents, adjusted for matrix composition and LOD requirements

    Downstream process integration

    • Preparation alongside matrix modifiers and masking agents
    • Addition after sample digestion or extraction steps
    • Final reagent addition before spectrophotometric reading
    • Batch-level archiving of all test results for regulatory records

    Final product types

    • Pharmaceutical API release testing kits
    • Bulk material QC assay reagents
    • Protocol-validated trace metal impurity panels
    • Stability testing support reagents

    4. Analytical Research and Instrument Calibration

    Producers of laboratory calibration standards and certified reference materials rely on this compound for preparing spectrophotometric iron calibration solutions. Accuracy in IR absorption and reproducibility under a range of matrix and storage conditions are essential. Reference material providers conduct multi-lot traceability checks and homogeneity studies according to ISO requirements. Cross-laboratory reproducibility and stability for long-term archival use are important for laboratories validating spectrometric equipment or conducting proficiency testing.

    Industry compliance standards

    • ISO 17034:2016 for reference material producers
    • ISO Guide 31: Reference materials — Contents of certificates and labels
    • ISO/IEC 17025:2017 for analytical laboratory operation
    • NIST SRM use protocols for cross-laboratory validation

    Typical usage ratio

    • 0.05–0.25 g/L in high-purity calibration solutions, concentration set per instrument’s linear calibration range and storage life requirements

    Downstream process integration

    • Weighing under controlled environmental conditions to minimize moisture uptake
    • Dissolving in ultrapure water and dilution to certified values
    • Aliquot filling into ampoules or volumetric flasks
    • Batch certification and certificate-of-analysis release for each lot

    Final product types

    • Iron(II) standard solutions for spectrophotometric calibration
    • Multi-ion research standards for laboratory quality assessment
    • Proficiency testing kits for water and biological iron analysis
    • High-precision calibration sets for instrument validation
    Free Quote

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    Certification & Compliance
    More Introduction

    Introducing Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate: Perspective from a Specialist Manufacturer

    Direct Experience with a Trustworthy Laboratory Reagent

    From a laboratory bench all the way to industrial analytical setups, Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate—CAS number 98614-47-4—commands attention due to its precise performance in colorimetric iron detection. We have dedicated years refining its synthesis, always monitoring the needs of chemists who count on consistency and purity. This product belongs to the class of water-soluble iron chelators; it stands apart by offering very high selectivity to ferrous ions even with the presence of complex sample matrices.

    Many research labs have told us stories about subtle but critical differences that a reliable ferrous indicator makes. Our chemists began with a clear challenge: deliver a salt that dissolves swiftly, produces no interfering impurities, and resists degradation under typical laboratory storage. Trace-level iron analysis—often performed in pharmaceutical quality control or drinking water monitoring—does not tolerate minor lapses. Our production lines stick to carefully titrated steps, stringently monitored atmospheres, and regular batch-to-batch testing. The end result: lots with consistent purity, reproducibility, and clear response during colorimetric assays.

    Chemical Model and Specifications—Why They Matter

    The molecular model, C24H14N2Na2O6S2·3H2O, provides little comfort unless it matches what comes out of the bottle in daily lab routines. Labs routinely ask about factors like moisture content, counter ions, and possible carryover from synthesis. We’ve found the trihydrate form hits a sweet spot for both stability and solubility. Batch analyses routinely measure sodium and sulfate levels and monitor for photodegradation byproducts—practices some suppliers skip, but which allow chemists at the user end to trust every run.

    Standard packing typically comes in sealed, light-resistant bottles—from 1-gram vials for research scale up to multi-kilogram kegs for testing or industrial monitoring services. We see users preparing fresh, concise aqueous solutions with no visible particulate or yellowing. They want both a rapid end-point and the absence of uncertain background colors—two qualities our production has focused on since early batches.

    Primary Application—Why Iron Quantification Relies on Quality

    Pharmacopeias and water regulators specify stringent upper limits for iron, given its catalytic role and potential for misleading test results. Our customers use Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate during iron trace quantification because it forms an intensely colored complex with Fe2+, easy to measure by spectrophotometry. The process is elegant yet unforgiving: even low-level contamination or improper stoichiometry can throw off the whole calibration.

    In drug manufacturing, for instance, a slight iron excess accelerates active pharmaceutical ingredient degradation. In municipal water testing, stray iron ions can confound readings for other metals. We support users who check not just for “presence of iron,” but chase sub-microgram uncertainties in every sample. They rely on our compound’s sharp end-point to avoid hours lost in troubleshooting faulty results.

    Comparing to Alternative Indicators—Small Details, Huge Differences

    Ortho-phenanthroline often appears in the same application space, but it struggles in aqueous environments and reacts less predictably across broad pH shifts. Ferrozine, another iron(II) indicator, reacts swiftly but sometimes carries interfering color, especially at higher sample concentrations. Out in the field, we have seen operators fight with re-precipitation, color drift, or decomposition—all of which risk a failed test and having to rework results.

    Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate avoids most of these pitfalls. Its charged sulfonic acid groups render it highly soluble in water, making aqueous analysis cleaner, more linear, and robust against pH interference within standard testing ranges. Working chemists often tell us they notice less scatter and steadier calibration slopes; the color development occurs without visible lag, which matters when high-throughput settings require dozens of readings per hour.

    Learning from the Challenges

    Several years ago, we ran into a tough period sourcing precursor phenanthroline. Pricing spiked, some lots arrived with excess metallic impurities, and a few even showed signs of oxidation. Rather than wait for raw material markets to stabilize, we set up new reagent purification lines, building out our analytical testing to catch even rare adulterants. This kind of behind-the-scenes work often means a higher up-front investment, but it creates a chain of trust all the way to the end-user.

    There’s another lesson in scale. Moving from gram-scale teaching sets to kilogram batches for industrial testing is not just about bigger vessels. We needed custom glassware, stricter humidity control, and a workflow that tracks every bottle with lot-level certificates. Early on, we learned to keep an extra eye on water activity, given how readily the trihydrate form exchanges moisture with the air, which can affect both longevity and actual iron detection accuracy.

    Everyday Use—Feedback from Real-World Chemists

    In university teaching labs, students always ask why a deep purple color indicates the “right” result. Rather than only look for pretty colors, we explain that this unique chromophore reflects a very specific Fe2+ complex, backed by quantum mechanics as much as visual detection. Pharmaceutical QC groups have run our salts through accelerated stability testing—heating, cooling, running test after test—and report little to no degradation under ordinary lab conditions.

    One of our oldest customers, working in environmental monitoring, regularly tells us that ease of use saves the day. Speed matters, but what really counts is confidence that calibration lines hold steady from one lot to the next. If even a single batch drifts, regulatory fines or customer trust could evaporate overnight. Our approach is both conservative in process and rigorous in monitoring—not because it’s fashionable, but because we’ve experienced the chaos that follows if these standards ever slip.

    Quality in the Details—Traceability, Certification, and Transparency

    No serious lab will compromise on trackable documentation. We maintain full analytical records for every lot—no exceptions. These records include typical tests for spectroscopic purity, sulfate and sodium analysis, and checks for color stability over storage. Auditors visiting our plants have full access to blending logs, chemical handling records, and environmental controls. Some might call this overkill, but regulatory agencies and high-accountability organizations require proof well beyond a basic certificate of analysis.

    Technical staff often request detailed spectra for each lot, and we're happy to provide them. Our investments in modern analytics—including atomic absorption and mass spectrometry—are not just for spotlighting our lab’s sophistication, but act as real guardrails against the unknown. Errors uncovered here save immeasurable time and credibility later on.

    Addressing Storage and Stability Concerns

    Proper storage means less waste, fewer re-tests, and fewer headaches. Early on, we saw the toll that poor packaging or out-of-spec suppliers wreaked on university labs and industrial testers. The trihydrate form, compared to anhydrous or monohydrate alternatives, holds up longer under typical storage but needs real attention to humidity. We introduced foil-lined and amber glass bottling across all scales. In rare, high-humidity zones, we also offer vacuum-sealed options on request, reducing caking and ensuring each sample gives a fresh, reproducible result.

    The best results always track back to thoughtful storage, controlled shipping environments, and a direct line to technical specialists for those times when users bump into unusual results. For forensic cleanup or high-stakes testing, contact with atmosphere—especially during hot, muggy months—makes a difference. We always advise labs to open only what they need and close bottles quickly, because the trihydrate’s slight water loss or gain can nudge analytical results.

    Supporting Sustainability and Safety

    We’ve taken concrete steps to make our operations more sustainable while keeping lab safety at the center. Our production system recycles solvents and neutralizes waste effluents before discharge. Engineers constantly review exposure risks, including air quality in reagent blending and packing rooms.

    Handling Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate does not present acute safety hazards in regular use, though our staff sticks to best practices to prevent dust inhalation and to avoid unnecessary environmental contamination. We keep MSDS documentation up to date and invest in staff training, both for our safety and any lab’s peace of mind. Caution makes for better results at every stage, from plant worker all the way to the analyst in the field.

    Ongoing Research and User-Focused Adaptation

    Recently, some research groups have been pushing further into trace-metal analysis, looking for ways to multiplex assays or measure ultra-low iron levels in complex biological fluids. Some instruments, especially high-throughput flow cells or bespoke microplate readers, demand even tighter control over reagent purity and solution behavior. Our R&D staff keeps in active touch with such frontline users. If their data shows side reactions, instability, or color shifting, we welcome the feedback; we adjust our synthesis or post-processing to fix problems before they become widespread.

    We’ve supported customers who need slight variations on standard specifications, such as different hydration levels or custom packaging configurations to fit robotic pipettors. As new regulations appear or detection thresholds drop, we invest in both modern analytics and more robust process controls.

    Trust Earned Through Fieldwork

    Questions about iron chelation never end at the laboratory door. Wastewater engineers, mine operators, and environmental consultants share stories about samples spiked with iron from rusted pipework or groundwater contamination. Dirty field conditions demand a reagent that won’t let the team down, even if the sample arrives late on a Friday. Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate—prepared as we guarantee it—forms complexes rapidly, even in less-than-pristine field samples.

    Field data rarely matches textbook examples. Real-world samples show variation in pH, total solids, and ion background. We’ve spent time working with analysts who validate our salt not only with clean lab water, but with real soil and water samples from mining sites, flood plains, and universities tracking groundwater remediation. User results regularly confirm the value of consistency—peak absorbance, minimal background, and predictable color intensity under quick, one-shot conditions.

    Continuous Improvement—Listening, Learning, Adjusting

    We are never content standing still. Every lot we ship brings us new feedback—questions about shelf life, worries about exotic interferences, even requests for more robust instructions. As science moves, we track trends and keep pace, ready to support new analytical challenges. If regulatory needs shift or detection thresholds set by the EPA or European agencies drop, we commit resources to recalibrate procedures and update support documentation.

    Many improvements in our process and packaging have come straight from user suggestions. Whether it’s adding more detailed batch-level data sheets, improving label durability, or offering more container sizes, the goal remains the same: give laboratories what they need to trust and perform at the highest level.

    Chemical Knowledge Base—Demystifying the Science

    Staff at our plant often host training sessions for local colleges and quality assurance teams. Beyond teaching analysis chemistry, we clarify real-world limits in sensitivity, color stability, and how interfering metals like copper or manganese may shift readings. Open dialogue helps users troubleshoot their methods, and it keeps us attuned to the next wave of demands coming down the pipeline.

    The chemistry driving Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate’s behavior—a planar aromatic with sulfonic substitutions—creates more than just a pretty color: it delivers high-affinity, low-background iron detection. These attributes are anchored in real molecular structure, not just on a spec sheet, and precise production secures those benefits for every bottle.

    The Value of Direct Manufacturing

    We control every step from raw chemical selection to final packing—no subcontracted mystery suppliers enter the chain. This is both a point of pride and a daily responsibility. We hear plenty from customers burned by surprise quality lapses out of their control, and we take their trust seriously.

    Direct relationships with analytical chemists, water authorities, and manufacturing labs shape not only our quality systems, but also our responsive logistics, batch documentation, and willingness to troubleshoot. New problems mean new solutions; direct feedback closes the loop much faster than distant trading layers or resellers disconnected from hands-on chemistry.

    Concluding Thoughts from the Production Floor

    For all the technical detail, the significance lies in keeping results trustworthy—from an undergraduate chemistry course up to the busiest environmental monitoring service. Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate rewards diligence at every level: thoughtful production, firm attention to chemical detail, and nimble response to user needs. Batches stay consistent; colors appear clean and expected; results stand up to scrutiny.

    Science does not rest on happy accidents—it depends on reliable tools and materials, produced by people who understand both chemistry and the real-world stakes. We stand behind Bathophenanthrolinedisulfonic Acid Disodium Salt Trihydrate not as a commodity, but as a product shaped by decades of experience and the trust of chemists worldwide. Every bottle reflects that standard, every time it leaves our plant.