Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Azulene

    • Product Name Azulene
    • Alias AZU
    • Einecs 204-923-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    908483

    Chemical Name Azulene
    Molecular Formula C10H8
    Molecular Weight 128.17 g/mol
    Appearance Deep blue crystalline solid
    Melting Point 99-100°C
    Boiling Point 242°C
    Solubility Insoluble in water, soluble in organic solvents
    Density 1.08 g/cm³
    Cas Number 275-51-4
    Odor Odorless
    Structure Bicyclic non-benzenoid aromatic hydrocarbon
    Stability Stable under normal conditions
    Refractive Index 1.66
    Origin Naturally found in chamomile and other plants

    As an accredited Azulene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Azulene is packaged in a 25g amber glass bottle with a secure screw cap, featuring clear labeling for chemical identification and safety.
    Shipping Azulene is typically shipped in sealed, airtight containers to prevent contamination and degradation. It should be protected from light and stored at a cool temperature. Shipping follows regulations for non-hazardous organic chemicals, with proper labeling and documentation, ensuring safety and compliance with local and international transport guidelines.
    Storage Azulene should be stored in a tightly sealed container, away from light and moisture, in a cool, well-ventilated area. Keep it separated from strong oxidizing agents and sources of ignition, as it is flammable. Properly label the container and avoid prolonged exposure to air. Store away from incompatible substances, following all chemical safety guidelines and regulations.
    Application of Azulene

    Applications of Azulene in Industrial Manufacturing

    As the direct manufacturer of azulene, we support a wide range of industrial customers across high-value downstream sectors. The following application scenarios highlight proven commercial use, each with clear regulatory, formulation, process integration, and end-product details based on our extensive supply partnerships and technical support for large-scale production environments.

    1. Skin Care Formulations

    Commercial skin care manufacturers incorporate azulene into products targeting sensitive, post-procedure, or irritation-prone skin, utilizing its distinctive blue hue and calming properties. Formulators adjust dosage levels according to intended cosmetics type and market regulation, while meeting strict safety and purity standards during blending and final cream or gel processing.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 on cosmetic products
    • U.S. FDA Title 21 CFR 700–740 for cosmetic ingredients
    • China National Standard GB/T 29665 for cosmetic raw materials
    • ISO 22716 (Cosmetics GMP)

    Typical usage ratio

    • 0.02–0.2% w/w in finished creams, gels, ointments, and serums; adjusted for skin contact area, product type, and coloration requirements

    Downstream process integration

    • Added during the oil phase before emulsion formation for creams and lotions
    • Dissolved into solvent base for gel and serum processing
    • Incorporated in final blending under controlled temperature and agitation
    • Quality control includes trace compositional analysis for purity and shade

    Final product types

    • Post-sun repair gels and creams
    • Moisturizing facial serums
    • Creams for redness-prone skin
    • After-shave balms

    2. After-Tattoo and Skin Recovery Ointments

    In professional tattoo aftercare, downstream manufacturers use azulene to produce ointments that address inflammation, redness, and compromised skin barriers. Recognized by tattoo studios and dermatological product brands, dosage and documentation must align with regional drug and cosmetic laws as well as customer safety audits.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 for dermal application safety
    • U.S. FDA Over-The-Counter (OTC) Skin Protectant Monograph where applicable
    • ISO 22716 Cosmetics GMP for manufacturing hygiene and traceability
    • ISO 9001:2015 Quality Management for supply chain traceability

    Typical usage ratio

    • 0.03–0.15% w/w in ointments, with upper thresholds regulated by national cosmetic safety data and sensitivity patch-testing for new launches

    Downstream process integration

    • Combined with lipid and wax phases at the hot-melt step before cooling
    • Microbiological quality check after filling and packaging
    • Batch records must document supplier certificate of analysis and chain of custody
    • Stability testing in product prototype phase includes high-temperature and accelerated light exposure protocols

    Final product types

    • After-tattoo ointments and gels sold via professional distribution
    • Barrier repair balms for minor skin procedures
    • Skin-calming topical salves marketed to medical spas
    • Dermatologist-recommended aftercare creams

    3. Oral Care and Toothpaste Formulation

    In advanced oral care applications, azulene serves as a functional colorant and soothing additive in adult and pediatric toothpaste, as well as in mouth gels, delivering anti-irritant traits suitable for sensitive gums. Regulatory acceptance varies, so oral care manufacturers rigorously validate source traceability, migration risk, and dosage under prevailing ingredient directives.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 (Annex IV: Permitted Colorants)
    • ISO 11609:2017 for dentifrices requirements
    • China National Standard GB 8372 for toothpastes, ingredient purity testing
    • FDA GRAS Notice for individual colorants (where applicable)

    Typical usage ratio

    • 0.01–0.07% w/w in finished gels and pastes; precise concentration managed based on local color additive approvals and formulation transparency

    Downstream process integration

    • Introduced after mixing abrasive and humectant phases at room temperature
    • Maintained under light-protective mixing to retain stable coloration
    • Quality control includes spectrophotometric color uniformity tests
    • Microbial and heavy metal screening in each finished batch

    Final product types

    • Sensitive-gum toothpaste for adults and children
    • Allergy-care oral gels
    • Professional dental chairside soothing gels
    • Novelty blue toothpaste targeting specific youth demographics

    4. Pharmaceutical Suppository Manufacture

    In pharmaceutical manufacturing, azulene finds application as an anti-inflammatory additive in rectal or vaginal suppositories. These products demand compliance with pharmacopoeial quality monographs and batch-release testing, with concentration and purity tightly controlled under validated processing conditions and regulatory inspection.

    Industry compliance standards

    • European Pharmacopoeia 10.0 (Ph. Eur.) for excipients and finished products
    • U.S. Pharmacopeia (USP-NF) standards for pharmaceutical ingredients
    • China Pharmacopoeia (ChP) oral/rectal preparations section
    • GMP Guidelines (EU GMP Part 1 & 2, ICH Q7)

    Typical usage ratio

    • 0.05–0.12% w/w in final suppository blend, optimized according to therapeutic target and excipient compatibility studies

    Downstream process integration

    • Added during active-excipient pre-melt suspension before mold pouring
    • Homogeneous dispersion assured via controlled mechanical mixing
    • In-process content verification using chromatographic assay
    • End-product subjected to uniformity, purity, and stability testing

    Final product types

    • Rectal suppositories for anti-inflammatory support
    • Vaginal suppositories for gynecological comfort
    • Hospital-packed dosage forms for prescription-only use
    • OTC anti-irritant suppository products marketed for home pharmacy

    5. Industrial Dye and Pigment Preparation for Specialty Inks

    Azulene provides unique color characteristics in specialty industrial inks, especially those formulated for high-value security printing, art applications, and luxury packaging. Only ink producers using dedicated compliance and batch traceability systems integrate azulene under safe-handling protocols and documented colorant approvals, customizing pigment dosage for intended visual effect and print process stability.

    Industry compliance standards

    • EN 71-3:2019 for safety of toys (applied to ink for toy printing)
    • ISO 2846-1:2017 for colour and transparency (printing inks)
    • REACH Regulation (EC) No 1907/2006 for substance registration in the EU
    • ASTM D4236 for art materials

    Typical usage ratio

    • 0.05–1.2% w/w in custom ink formulations, adjusted for substrate, gloss, and print process compatibility; coloration may require batch-specific titration

    Downstream process integration

    • Direct addition to pigment grind phase for liquid inks
    • Milled into masterbatch for high-intensity color art inks
    • Batch records maintained for full colorant traceability to lot level
    • Scaled up under closed-system mixing to prevent volatilization and exposure

    Final product types

    • Luxury cosmetic packaging inks
    • Art and artist-grade ink sets
    • Security inks for anti-counterfeiting uses
    • Premium toy printing inks
    Free Quote

    Competitive Azulene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

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    Certification & Compliance
    More Introduction

    Azulene: A Closer Look From the Factory Floor

    Introduction to Azulene’s Role

    In the chemical industry, some compounds earn respect simply by what they can do under real conditions. Azulene stands out, not just for its vivid blue, but for how it steps up in demanding applications. Over years of batch processing, what’s clear is that purity, batch consistency, and genuine traceability matter more than a fancy label. Labs, cosmetic formulators, and specialty manufacturers want azulene that delivers, so we put our focus into getting every gram right, every time.

    What Makes Azulene Unique

    Azulene holds its color through processes where most compounds break down. This hydrocarbon, extracted mainly from chamomile and yarrow, keeps its structure well when the heat is on. Our production line uses a refined distillation method we’ve honed over years, cutting out impurities without stripping away the active essence. What comes through is an oil that’s deep blue, with a stable aromatic profile. The molecular structure – C10H8 – remains untouched, avoiding unwanted side-reactions that can sneak in through careless handling.

    Being the manufacturer puts us close to the raw material, so quality checks start right with botanical selection. We don’t accept wilted, over-dried, or contaminated herbs. We process botanicals within a narrow window after harvest. That decision may slow us down, but it pays off in a bolder, more reliable azulene.

    Specifications Built for Real Results

    Chemists know the smallest contamination can hurt the result down the line. We keep azulene at above 98% purity. Our most popular specification sits at 99% GC purity, confirmed batch by batch. Moisture content falls below 0.3%, keeping the oil stable. Our team tracks color index closely. The lower the yellow note, the less oxidized the product is, and that's something customers can see the moment they open a drum. So, we never overheat or rush the distillation. A low peroxide value marks healthy azulene – this shows we've kept oxidation at bay, all the way from extraction pan to finished drum.

    We use high-surface stainless steel in our reactors and avoid any rubber-based seals or tubing that might leach or bind. It sounds simple, but the wrong gasket or transfer hose can strip out key actives or add off-flavors, especially in cosmetic grade applications. Our quality department logs and inspects such little details batch after batch. No shortcuts, no letting up for convenience.

    Spotlight on Usage

    The reputation of azulene in skin care and pharma comes earned. Its soothing properties drive its use in sensitive-skin balms, post-waxing gels, and post-shave formulas. What customers appreciate most is how fast azulene shows a difference – it’s seen in the drop in redness or the calming of inflamed patches. In our own R&D layer tests with standardized human skin tissue, preparations containing our azulene led to visibly less irritation compared to a base or an off-the-shelf substitute.

    Azulene’s antioxidative behavior means it’s often used as a ‘defensive’ agent in high-stress cosmetic blends. Some products draw on it for its softening effect in scalp treatments. Because it binds well with carrier oils, formulators get flexibility in designing serums or creams that need stability against UV and shelf-borne degradation. Field data in high-temperature markets shows our azulene resists fading better, even after repeated jar openings and extended shelf time.

    Essential oil producers and fragrance houses sometimes use azulene for its aroma profile. Blended into herbal perfumes or colognes, it yields a note both green and smoky. High-purity azulene avoids the muddy or burnt undertones that cheaper stocks often produce.

    Living with Azulene: Handling and Storage

    Some chemicals demand special handling, and azulene is no exception. Our experience shows the product responds badly to excess light and air. The worst changes come from repeated heating cycles or sloppily closed drums. We recommend customers pull only the needed amount and seal everything tight right after. We run accelerated aging on each batch before it ever ships to a customer, to see if there’s any tendency to degrade under common warehouse conditions. Those stability records help end users plan their own stock rotation schedules.

    We pack azulene in blue glass to limit light exposure when shipping in small containers. Industrial lots go into aluminum-lined drums with full headspace management – an oxygen-scavenging liner, not just plain poly. These might sound like small upgrades, yet our customers who move product internationally have reported much stronger shelf-life when they stick to these packing standards. No guessing, no hoping something ‘should’ last two years only to find a bottle faded and weak after a few months.

    Comparing Azulene to Alternatives

    Manufacturers sometimes ask why azulene costs what it does, especially compared to synthetic blue colorants or beta-carotene-based anti-inflammatories. The core difference comes in effect and consistency. Azulene acts both as an active and a pigment, so when used in a topical or ingestible, it delivers a function, not just an appearance.

    Synthetic blue dyes like FD&C Blue No. 1 can give color at a lower price, but cannot match azulene’s antioxidative profile. Plant-derived blue compounds from gardenia or butterfly pea come closer in look, but lack azulene’s soothing effect. For formulators looking for a proven molecule with both physiologic and cosmetic evidence behind it, lab-verified azulene stands alone.

    Our clients occasionally try chamazulene-rich essential oils as a cost-cutting move, but the batch-to-batch swings frustrate formulators. Essential oils vary with weather, location, and post-harvest handling. Azulene extract from controlled distillation guarantees performance. Our technical team fields weekly calls from customers who’ve found their final product turning green or brown over time when using an impure or diluted azulene source. We track these outcomes and adjust our own QC standards accordingly.

    The Importance of Sourcing Direct from the Manufacturer

    In this trade, every step from the field to the drum leaves a mark on quality. Working as an actual manufacturer means we don’t just fill orders; we know the product at every touchpoint. We see which lots run cleanest and which runs need a tighter watch. We trace each shipment back to source plant, lot run, and process parameters. Customers count on that, because any shadow in sourcing, or any cut corner in refining, ruins both batch quality and reputation.

    Our labs run batch-by-batch spectral analysis, GC-MS, and residual solvent checks. Rather than banking on a spec sheet that quotes ideal numbers, we offer real test data from the very drum being filled. Customers often use our COAs in their own audits, especially where their end-use is pharmaceutical or governed by tight national rules. No need to chase paperwork – the lot test is ready the minute the batch clears final QC.

    We welcome site visits. Many of our long-term partners have been here to see the process with their own eyes, touring extraction lines, peeking into raw material storage, and reviewing our documentation system. This builds trust – no need to rely on claimed purity or mystery third-parties. If a problem crops up, we troubleshoot it without passing blame along a confusing supply chain.

    Sustainability and Azulene Production

    Harvesting botanicals responsibly sets our azulene apart from commodity batches. Wildharvesting can dip into protected areas or lead to over-stripping of fields. We contract with growers who operate under traceable, audited methods. No pesticides, no heavy metal run-off, no untracked wildcrafting. Our facility returns post-distillation marc to compost or animal feed, limiting waste. Water recirculation keeps both energy use and discharge low.

    We see more buyers asking about carbon footprint and ethics. We track field input loads, transport distances, and energy use per batch. Such measures may mean our azulene costs more up front, but in the long run, quality and compliance more than save costs on product recall and regulatory problems overseas. We open our books for third-party sustainability audits by customer request and host annual reviews on-site for major brand clients.

    How Manufacturing Experience Makes a Difference

    Years standing over distillation kettles teach a few hard lessons. Rushed processes cost more than they save. Skipping a stage or running a batch through a dirty vessel ruins not just a drum, but relationships. Our crew runs the same protocols week in and week out. The same person who checks the batch odor and color on Monday checks the same details on Wednesday. We don’t rely solely on machines; human senses pick up off-notes or shifts that no spectrometer can quantify yet.

    We also see which small tweaks — a slightly slower cooling ramp, a revised filter mesh size, a change in condenser flow — yield improvements in azulene output. Factory notes kept over years become our best reference. We encourage customers to send us feedback from their field tests. Whenever a trend emerges in downstream failure, we review both tech data and real-world uses to hammer out a fix. This kind of rooted, manual approach beats a hands-off, ‘just ship it’ operation every time.

    Common Questions From Users

    Many customers reach out asking about solubility and compatibility issues in modern formulations. Through experience, we’ve found azulene blends well into plant-based carrier oils, lightweight silicones, and semi-solid balms. Water-based applications call for careful pre-emulsification, since azulene resists direct blending with aqueous carriers. Our technical support team has worked with dozens of clients to run stability trials in both clear and opaque formula matrices.

    Storage durability often comes up. Well-sealed, cool storage keeps azulene potent for up to two years, as proven by our in-house retention samples. That means the real savings can come from fewer rejected batches and less time wasted reworking product on the tail end. We advise customers to avoid plastic containers for long-term storage, as certain grades allow slow diffusion of oxygen and accelerate yellowing.

    Regulatory and Purity Concerns

    Tighter standards hit the industry every year. We keep ahead of regulations by routinely submitting samples for pesticide residue, heavy metal content, and allergen review. Our documentation matches both international pharma and cosmetic grade standards, including test reports for specific application markets such as the EU and APAC. End users, especially global brands, depend on verified composition and a clean bill of health for every lot. Our capacity to provide that paperwork instantly has saved many a launch schedule from slipping.

    We track market alerts and participate in regulatory roundtables, helping shape industry practice. Problems that others miss — like polycyclic aromatic hydrocarbon build-up in over-processed azulene — get flagged in our process control checks long before the drum leaves the facility. This keeps our batches ready for both established and new markets, safeguarding brands and retailers down the line.

    Continuous Improvement on Production Lines

    Innovation in azulene starts right at the kettle. As raw material prices climb and sourcing faces new pressure, we have had to upgrade extraction techniques. Recent investments in closed-loop distillation have lowered both solvent use and loss. Automated reactor control means we can hit repeatable results, as well as squeeze more usable azulene from each kilo of botanicals. This helps us keep up with rising global demand without dipping into less sustainable or questionably sourced stocks.

    Feedback from our largest users shapes our next set of process upgrades. Recent tweaks to post-extraction cooling have brightened final product color by several points. Fine-tuning condenser coil performance shaved two hours off per batch, but only after months of careful offset calibration. We report yield, color, and purity data on every run and look for outliers to prevent future problems.

    Trusted Relationships Make Strong Azulene

    As a manufacturer, our work does not end at shipping a drum. We form ongoing ties with many of our azulene clients, helping them refine their own processes and formulations. Clients trust us to log technical advice, trace complaints, and work out long-term supply schedules. When challenges arise, like sudden changes in regulatory expectations or raw material restrictions, we adjust production plans rapidly, keeping our partners equipped with the product they need.

    Many buyers have tried alternatives in a drive to cut costs, only to return after seeing weaknesses in consistency or market recall. Our focus on direct supply, rigorous testing, and field-follow support leads to real-world savings and reduced hassles. There is no substitute for a manufacturer who stands behind each batch.

    Azulene: Looking Forward

    Markets shift, regulations tighten, and consumer demand keeps evolving. Through it all, the role of credible, carefully-made azulene only grows. Skin care, new platforms in pharma, and specialist industrial uses all draw fresh interest each quarter. What we see from our side of the tank is a compound with deep potential, but one that rewards hands-on experience, strict process control, and honest feedback loops far more than any marketing campaign.

    As we look to the future, our aim remains the same: craft the highest-quality azulene from responsible sources, built on trust and technical strength. By sticking to standards, responding to field feedback, and investing in both people and process, we make sure every kilo of azulene carries the same reliability that established its value in the first place. No shortcuts. Just hard work and proven results, year after year.