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Anthraquinone-2-Carboxylic Acid

    • Product Name Anthraquinone-2-Carboxylic Acid
    • Einecs 207-482-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    122459

    Cas Number 117-78-0
    Molecular Formula C15H8O4
    Molecular Weight 252.22 g/mol
    Iupac Name 9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
    Appearance Yellow to orange powder
    Melting Point 285-288°C
    Solubility In Water Slightly soluble
    Synonyms 2-Carboxyanthraquinone; 2-AQCA
    Purity Typically ≥98%
    Storage Temperature Room temperature
    Boiling Point Decomposes before boiling
    Density 1.652 g/cm³
    Pka 3.8 (carboxylic acid group)
    Smiles C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3C2=OC(=O)O
    Ec Number 204-214-7

    As an accredited Anthraquinone-2-Carboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 100g Anthraquinone-2-Carboxylic Acid comes in a sealed amber glass bottle with a tamper-evident cap and hazard labeling.
    Shipping Anthraquinone-2-Carboxylic Acid is shipped in tightly sealed containers, protected from moisture and direct sunlight. Standard packaging includes HDPE bottles or fiber drums with inner liners. The product should be labeled according to hazardous goods regulations and transported in compliance with local, national, and international chemical transportation guidelines. Handle with care.
    Storage Anthraquinone-2-carboxylic acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of heat, moisture, and incompatible substances such as strong oxidizing agents. Protect it from direct sunlight and avoid freezing. Ensure that storage areas are labeled appropriately and that access is limited to trained personnel.
    Application of Anthraquinone-2-Carboxylic Acid

    Applications of Anthraquinone-2-Carboxylic Acid in Industrial Manufacturing

    Anthraquinone-2-carboxylic acid serves as a specialized intermediate in multiple chemical industries. As the original manufacturer, we provide high-purity grade material, meeting the needs of advanced downstream synthesis, colorant formulation, and specialty chemical production settings.

    1. Dye and Pigment Intermediate for Vat Dye Manufacturing

    Manufacturers use anthraquinone-2-carboxylic acid as a core building block in producing high-performance vat dyes. It enables effective synthesis of blue and green shades, especially for textile applications. The acid enters sulfonation or halogenation steps, undergoing further condensation to create dye molecules with excellent wash and light fastness. QC teams monitor for metal impurities and by-product residues to meet textile industry standards. The product supports high loading in dye-forming reactions with adjustments according to batch scale and color strength requirements. Technical teams integrate the material at the primary coupling or ring transformation phases, optimizing for purity and reactivity. Typical end products include indanthrene blues and related anthraquinone-based dyes.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006
    • ZDHC MRSL compliance for restricted substances
    • OEKO-TEX Standard 100 for harmful substances in dyes
    • ISO 105-B02 for dye color fastness to light

    Typical usage ratio

    • 5–18% of total reactant mass, adjusted by target dye chroma and batch size

    Downstream process integration

    • Enters initial condensation or sulfonation stages in dye synthesis lines
    • QC sampling after ring modification reactions

    Final product types

    • Vat Blue 1, Vat Green 1 dyes
    • Anthraquinone-based textile pigments
    • Semi-finished dye formulation intermediates

    2. Agrochemical Synthesis: Herbicide and Fungicide Precursors

    Formulators in agrochemical manufacturing utilize anthraquinone-2-carboxylic acid to develop advanced herbicide and fungicide molecules. It supplies the required anthraquinone backbone for further functionalization, supporting selective crop protection agents. Synthesis operates under tightly controlled conditions to avoid cross-contamination and ensure batch purity. Supervisors monitor for compliance with pesticide registration and environmental safety norms. The acid is dosed at specific points during precursor synthesis and coupling reactions, depending on the desired biological activity profile. Final agrochemical active substances derived through these processes deliver targeted mode-of-action properties.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • EC 1107/2009 Regulation for Pesticide Approval (EU)
    • US EPA Pesticide Chemical Residue Tolerances
    • ISO 1750 pesticide common names and definitions

    Typical usage ratio

    • 8–15% by mass in key coupling steps, depending on target molecule structure

    Downstream process integration

    • Feeds into intermediate coupling or cyclization reactions to form active ingredient precursors
    • Analytical sampling after condensation stages to verify conversion rate

    Final product types

    • Anilide-based herbicide active ingredients
    • Antramycin-type fungicide lead molecules
    • Registered technical agrochemical intermediates

    3. Organic Electronics Materials: Dye Sensitizer Synthesis

    Specialty chemical processors select anthraquinone-2-carboxylic acid for synthesizing organic dye sensitizers used in dye-sensitized solar cells (DSSC) and electronic inks. The compound’s ring structure allows precise tuning of electronic and optical properties. Production lines integrate the acid into ring-closing and functionalization reactions that demand high-purity standards for electronic applications. Technical guidelines require process documentation for traceability and control of metallic contaminants. The input mass ratio varies by device design and target electron-donor characteristics. The main output includes sensitizer molecules tailored for specific light absorption profiles in energy harvesting devices.

    Industry compliance standards

    • RoHS Directive 2011/65/EU
    • IEC 62047 standards for electronic organic materials
    • Internal QC protocols for lab traceability and purity assurance
    • Material-specific ICP-OES heavy metal limits

    Typical usage ratio

    • 3–10% in dye-forming reactions, adjusted by molecular design

    Downstream process integration

    • Integrated in early-stage functionalization and closing reactions on dye manufacturing lines
    • Post-reaction purification steps using chromatography or membrane filtration

    Final product types

    • DSSCs (dye-sensitized solar cell sensitizers)
    • Organic electronic inks for flexible displays
    • Binary organic photoconductor blends

    4. Pharmaceutical Intermediate for Antitumor and Antibacterial APIs

    Anthraquinone-2-carboxylic acid serves as a key intermediate for active pharmaceutical ingredient (API) producers manufacturing molecules with anticancer and antibacterial profiles. Controlled GMP manufacturing lines introduce the acid in coupling, acylation, or amidation reactions that yield pharmacologically relevant anthraquinone derivatives. Quality teams conduct full batch traceability, impurity profiling, and pharmacopoeia compliance checks at each stage. Formulation chemists adjust the input loading depending on target yield and downstream process validation data. End products include semi-synthetic or synthetic agents for advanced oncology and anti-infection drug pipelines.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP, EP pharmacopoeial monographs for related APIs
    • 21 CFR Part 210/211 FDA cGMP regulations
    • EMA Guidelines on the Quality of Active Substances

    Typical usage ratio

    • 10–18% input mass, optimized by yield calculation and validated process flow

    Downstream process integration

    • Coupling, ring-closing, or acylation steps in multi-stage API syntheses
    • In-process controls after every transformation and final crystallization

    Final product types

    • Synthetic anthraquinone antitumor drugs
    • Semi-synthetic antibacterial agents
    • Pharmaceutical intermediates for further derivatization
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    Certification & Compliance
    More Introduction

    Anthraquinone-2-Carboxylic Acid: A Manufacturer’s Perspective

    Direct from the Source: Experience Behind the Product

    Every chemical that leaves our workshops carries years of booms and setbacks, trial batches and breakthroughs. Among what we produce, anthraquinone-2-carboxylic acid stands out for its practical value and consistency, built on a solid backbone of reliable synthesis. Working in this field, we’ve watched raw materials change, customer specs tighten, and downstream products climb in complexity. Many buyers want to know how this compound acts, how it differs from others off the same scaffold, and what can be expected from the people who actually run the reactors.

    Knowing Anthraquinone-2-Carboxylic Acid: Structure, Purity, and Routine Production

    Day to day, anthraquinone-2-carboxylic acid (often shortened as AQCA or AQ-2-COOH) moves from our plant to pigment makers, specialty dye shops, research institutes, and manufacturers in need of specialized intermediates. Most of the material rolls out as a fine pale orange to yellow powder, though slight color variations happen batch to batch—a natural result of scale and starting stock. We follow thorough purification steps to ensure high assay: regular lots reach or exceed 97%, confirmed by HPLC and melting point checks, with water and ash content tightly controlled.

    Our production uses well-monitored air oxidation and carboxylation, with careful isolation to strip away isomeric impurities and residual solvents. The carboxylic group at the 2-position is critical, shaping how this molecule interacts with coupling partners and downstream substituents. Anyone opting for the closely related anthraquinone-1-carboxylic acid or 1,8-dicarboxylic acid will notice differences in solubility, reactivity, and end-use applications, sometimes only visible after scale-up or in synthetic sequences demanding utmost selectivity.

    Model Numbers and Grades: Precision with Purpose

    Market demand often pushes us to keep more than one model or grade. Our base grade (labeled AQCA-970) works well for most dye intermediate tasks. Higher-cleanness (AQCA-990, assay above 99%) is reserved for research and electronic industries, where customer analytical requirements can be rigorous. Lab and kilo-scale buyers need batch data for every lot—they get full COA and spectral runs. For bulk, paint, and dye customers, the focus shifts from ultra-trace metal content to bulk handling, color stability, and freedom from residual process solvents.

    The temptation for buyers is to treat all anthraquinones—no matter their positionals—interchangeably. Weekly, a few requests drift in for “anthraquinone carboxylic acid, any position.” Experience shows that yields, solvent choices, and filtration times shift dramatically based on the carboxyl location, even if the core structure stays similar. Reactivity with amines, coupling partners, or diazonium salts gives different outcomes. The 2-carboxylic acid, in particular, performs better in certain vat dye and pigment syntheses, while its 1- and 1,8- counterparts find favor in more limited fields.

    Practical Uses: Why End Users Keep Coming Back

    Downstream, anthraquinone-2-carboxylic acid moves into everything from dye manufacture to organic electronics and some new pharma intermediates. For vat dyes, it brings stable core coloring, lightfastness, and steady bath-to-bath yields. Its structure lets it serve as a scaffold for further substitution, so dye makers reach out for troubleshooting tips when color drift appears or unreacted starting acid lingers in product. In the pigment sector, its high thermal stability means our powder walks through high-heat processes with little decomposition; it holds up in extrusion and blending, even when pigment mills run at speed.

    Researchers searching for specialty aromatic acids often run up against minor isomers contaminating standard market samples. Our plant, by running larger scale yet keeping purification steps robust, sometimes gets orders from universities and R&D groups abroad who had bad luck with traders or inconsistent stocks. It’s in these moments—when a reliable sample unlocks a new synthetic pathway or makes a new chromophore possible—that you understand why a tight production line and honest COA matter.

    Comparisons with Similar Compounds: The Value of Positional Selectivity

    Some buyers, especially those outside direct dye manufacturing, ask why not use anthraquinone itself, or simply another carboxylic acid isomer. The short answer: the position of the carboxyl group on the anthraquinone ring governs everything from solubility and melting point to downstream reactivity. Our 2-carboxylic acid resists easy substitution by competing nucleophiles, offering higher selectivity—no small feature if your process skews easily with even small changes in input. The 1-isomer, by contrast, finds fewer takers outside of very specific pharmaceutical pathways, while the 1,8-compound, with two carboxylic acids, brings complexity and occasionally unwelcome byproducts if not handled precisely.

    Through years of synthesis, we’ve seen dye producers attempt to substitute a cheaper or more readily available anthraquinone acid in a pinch—yields sag, side reactions spike, and product colormetrics shift outside spec. Product uniformity at the molecular level supports consistency in the vat, on the mixing line, and downstream for the end-user, whether coloring textiles or building molecular electronics.

    Troubleshooting Real-World Challenges in Production and Application

    Every batch that rolls out brings small challenges. Anthraquinone derivatives show batch-to-batch variation in color and residue, especially when atmospheric humidity surges or starting stock varies. Over time we have altered our drying and storage procedures: in monsoon months, all powder cools under dry nitrogen, while in drier seasons we test for airborne contamination regularly to prevent dust pickup or caking. Long-term partners appreciate our habit of describing any batch differences in plain language, so surprises downstream are rare.

    Another recurring issue comes from reaction byproducts and trace contaminants. Some older pathways leave behind trace phthalic acids or over-oxidized species, which might not show in cursory tests but ruin a delicate organic synthesis. By investing in upgraded reactors and downstream purification (better liquid-liquid extraction, finer crystallization procedures), our quality tracks closely with the most demanding customer specs. Acid-wash glassware and regular equipment overhaul further cut risk of cross-contamination—minor investments that pay off in repeat business and customer trust.

    Handling in bulk brings its own learning. Anthraquinone-2-carboxylic acid does not flow like ordinary powders. Large bags clump unless anti-caking steps are followed. We now condition and package at low RH, then offer custom packaging for customers who need to meter out kilos at a time for automated feed systems. Where crumb formation posed a problem, we shifted to finer mesh sieving and vibratory screening before packing—a small step that pays off in fewer process hiccups once the customer starts their shift.

    Environmental and Safety Considerations: Building for Today and Tomorrow

    Regulation grows stricter each year—rightly so. Many dyes and dye intermediates risk environmental and worker exposure when proper handling lapses. We worked with local inspectors and third-party auditors to bring our discharge systems, ventilation, and packing areas up to mark. Unlike many resellers or traders, we see firsthand both the waste stream from anthraquinone acid production and the way powders behave in the air. We batch in closed systems, capture fines for recycling, and operate on zero-waste principles where possible. Regular staff training cut our minor incident rate, while customer feedback helped us catch a packaging flaw (one sealant compound wasn’t inert enough under some storage conditions—now replaced across all lines) before it built into a recall issue.

    Some of our chemical byproducts, if handled poorly, could create a regulatory headache or worse. By keeping detailed reaction logs and batch records, we locate and isolate any hiccup fast. Traceability, long a watchword in pharma, pays off for dye intermediates too—so we keep careful sample archiving, and welcome even tough customer audit requests.

    Most buyers want basic MSDS and GHS-compliance, but the more discerning clients seek evidence: Are we capturing all process vapors? How about handling of heat and oxidant residues? Our approach is open-door—walk-throughs of every safety patch, clear records of stack emissions, and a dedicated QA team. These details shape not just our anthraquinone-2-carboxylic acid, but the overall health of business and worksite alike.

    Partnering with Customers for Real Results

    Years back, a dye house in Turkey sent us recurring queries about unexpected graying in certain turquoise blends. Over several joint investigations, logging every variable—grinding temperature, acid concentration, diluent selection—we traced the issue to a trace meta-isomer remaining from a poorly-controlled oxidation step. Our R&D adjusted reaction time and swapped an aging vessel for a freshly-lined one. Not only did yield and color reproduction bounce back, but their feedback loop gave us better process control, lowering rejects in other plants too.

    Elsewhere, a startup building organic semiconductors needed unusually high-purity anthraquinone-2-carboxylic acid, free from halide residues. Rather than ship regular plant output, we recalibrated our purification for this trial, ran full traceability, and provided not just a sample but support on long-term storage and handling. Their follow-up—the compound withstood their thin-film electron testing, without haze or unexpected dropouts—brought more than repeat business. It brought insight into new grades and setups that now feed back into our own improvement cycles.

    Why Direct-from-Manufacturer Supply Changes the Game

    Many buyers try the open market first, only to struggle with off-grade stocks, erratic COAs, or missing lot data. As a direct manufacturer, we answer questions trade shops and warehouses can’t—where a batch started, what feedstocks it drew from, and how each QC dipstick result compared to plant average. This level of detail matters when regulatory filings, intellectual property filings, or sensitive R&D projects hang in the balance.

    Manufacturing at scale also means the plant learns fast: a run with off-color cues gets flagged on the line, long before it makes it to a warehouse. Lab-to-bulk consistency forms the core of our work—not a paperwork exercise, but a daily test as each order leaves our door. By supplying direct, we close the loop, catching any process drift and updating customers with first-hand fixes. Feedback—good or bad—moves fastest this way, strengthening ties and building real trust.

    Looking Forward: Adjusting to New Demands and Uses

    The landscape for anthraquinone-2-carboxylic acid keeps shifting. Growth in renewable dyes, functional pigments, and advanced organic materials asks for ever-tighter specs, cleaner profiles, and flexible scale. We adapt—new filtration trains, bulk handling for automated processing, assay by LC-MS for ultra-low byproducts. Industry pressures have made us more nimble: we turn round new test batches, shoulder up to changing customer trial plans, and consult directly on process improvements or new synthetic routes.

    Buyers probing greener processes press for reformulated process solvents and alternative oxidants. Our plant pilot-tested less harsh oxidizing agents and shifted to improved solvent recovery. Cleaner waste streams, higher overall recovery, and sustainable sourcing add up to long-term gains, even if short-term costs run higher. Our experience shows these changes win loyalty from customers who watch the full life cycle—from raw input to final, dyed fiber or device. Their trust remains the best endorsement for the extra effort behind the scenes.

    Listening, Improving, and Staying Accountable

    We have kept open dialogue lines, inviting customer audits and site visits that go beyond paperwork. Feedback from frustrated pigment mills or labs chasing elusive reproducibility does not land in a suggestion box—engineers log issues, we track corrections, and adjust process trains. The learning loop is never closed: today’s batch variation, if properly understood, builds tomorrow’s better product. Suppliers, in truth, learn as much from tough downstream applications as from their own QC logs. Because of direct supply, open troubleshooting, and a focus on root-cause fixes, our anthraquinone-2-carboxylic acid carries the stamp of continuous improvement, not just good enough for spec sheets, but good enough for practical, real-world use.

    In Conclusion: Real Work Builds Real Chemistry

    The story of anthraquinone-2-carboxylic acid at our plant is not just a rundown of specs or a table listing assay values. It’s the ongoing dialogue between the shop floor, plant engineers, QC teams, and end users scattered across the textile, pigment, and materials science fields. Decades of watching this compound, its behavior under pressure, its quirks in the vessel, and its journey across the world have shaped the way we make and provide it. For those who want reliable, explainable chemistry—grounded in lived experience and open communication—our doors are always open, and so are our records. The chemistry doesn’t just happen in the vessel. It happens in every conversation, every tweak, and every shared solution, with anthraquinone-2-carboxylic acid as the meeting point between precision manufacturing and real user need.