|
HS Code |
460274 |
| Cas Number | 10497-10-4 |
| Molecular Formula | C8H15NO2 |
| Molecular Weight | 157.21 |
| Appearance | White to off-white solid |
| Melting Point | 149-153°C |
| Purity | Typically ≥98% |
| Solubility In Water | Slightly soluble |
| Storage Conditions | Store at room temperature, dry place |
| Synonyms | 2-Amino-2-cyclohexylacetic acid |
| Smiles | C1CCC(CC1)C(C(=O)O)N |
| Inchi | InChI=1S/C8H15NO2/c9-8(7(10)11)6-4-2-1-3-5-6/h6,8H,1-5,9H2,(H,10,11) |
| Usage | Intermediate for pharmaceutical synthesis |
As an accredited Amino-Cyclohexyl-Acetic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White plastic bottle labeled "Amino-Cyclohexyl-Acetic Acid, 100g." Features hazard symbols, batch number, and tightly sealed screw cap. |
| Shipping | Amino-Cyclohexyl-Acetic Acid is shipped in tightly sealed, chemical-resistant containers to prevent contamination and moisture exposure. Packaging complies with regulatory standards for chemical safety. During transit, the material is protected from extreme temperatures and rough handling to maintain its integrity. Proper labeling ensures safe and compliant transportation. |
| Storage | Amino-Cyclohexyl-Acetic Acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Protect it from moisture and direct sunlight. Store at room temperature, and ensure containers are properly labeled. Always follow all relevant safety and regulatory guidelines when handling and storing this compound. |
Applications of Amino-Cyclohexyl-Acetic Acid in Industrial ManufacturingOur production-grade Amino-Cyclohexyl-Acetic Acid (ACA) supports a select range of industrial manufacturing sectors. The following segments illustrate current, real-world incorporation in downstream industries, summarizing market-driven practices and regulatory frameworks. Explore how ACA integrates into specific applications, with technical insights into standards compliance, formulation roles, typical process steps, and finished goods output. 1. Pharmaceutical API Intermediate in CNS Drug SynthesisPharmaceutical producers incorporate ACA as a building block for synthesizing central nervous system (CNS) drug intermediates, particularly in the development of cyclic amino acid derivatives for specialty active pharmaceutical ingredients. ACA is valued for its cycloalkyl structure, offering unique steric arrangements during salt and ester formation steps in multi-stage batch synthesis. In these processes, close monitoring of raw material purity and trace metal content remains necessary for active substance consistency and regulatory adherence. Industry compliance standards
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2. Fine Chemical Synthesis for Agrochemical IntermediatesManufacturers of specialty agrochemicals harness the aminocyclohexyl moiety of ACA as a precursor for producing compounds with selective herbicidal and fungicidal activity. ACA provides a platform for building more complex molecular scaffolds, with process emphasis on controlling isomer ratios and minimizing side-product formation during functionalization. Careful compliance with chemical manufacturing and environmental standards underpins these syntheses, particularly for export-focused facilities. Industry compliance standards
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3. Chiral Starting Material for Specialty Polymer ModifiersIndustrial polymer manufacturers use ACA to derive monomers and chain extenders with cyclic amino acid groups, directly affecting the steric and thermal properties of specialty resins and elastomers. This application responds to increased demand for tailor-made polymer additives designed for medical devices and precision industrial components, where consistent molecular geometry and impurity profiles are crucial. Product validation adheres to both polymer-specific and end-use compliance protocols. Industry compliance standards
Typical usage ratio
Downstream process integration
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4. Analytical Reagent ManufacturingProducers of laboratory-grade analytical reagents utilize ACA as a precursor in the preparation of calibration mixes and derivatization standards for chromatographic analysis. Its defined stereochemistry enables development of reference standards crucial for accurate quantitation in HPLC and GC assays. Manufacturers focus on batch reproducibility and certification under recognized reagent quality systems to guarantee downstream traceability and laboratory compliance. Industry compliance standards
Typical usage ratio
Downstream process integration
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Each batch of Amino-Cyclohexyl-Acetic Acid that rolls off our line reflects years of cumulative experience in chemical synthesis. The journey turning raw materials into this valuable intermediate involves precise handling at every step. Our operators recognize the importance of minor details—temperature control during reactions, specific solvents, and evaporation points that help yield a product with consistent quality. Such care doesn’t just show respect for chemistry; it shows respect for the people downstream putting trust in what we make. One might overlook the impact of a single intermediate, but by working with Amino-Cyclohexyl-Acetic Acid every day, its place in synthesis becomes obvious.
We see demand for Amino-Cyclohexyl-Acetic Acid from researchers, development teams, and manufacturers with a clear goal in mind. They want a consistent building block that can anchor synthetic routes toward pharmaceuticals, advanced materials, or specialty chemicals. The molecular structure—a cyclohexane ring bearing both amino and acetic acid functions—carries versatility. Our R&D chemists identified early that small changes in route or environment can shift the purity of the end product or generate unwanted isomers. By refining the process over repeated campaigns, we’ve learned control. That reliability opens options for those designing new molecules, not just replicating what’s on paper.
We manufacture Amino-Cyclohexyl-Acetic Acid in both technical and high-purity models. Feedback from our key partners—pharmaceutical innovators in Asia and materials firms in Europe—drove us to tighten specifications beyond industry baseline standards. We routinely measure by HPLC and GC, with clearly defined limits for related substances, moisture, and residual solvents. Production engineers on our line calibrate every analytical run against retained reference samples, and we never shy away from pulling up data from a two-year-old batch if a customer has a question. Most outsiders only see the number on the COA, not the routine cross-checking that stands behind it. That vigilance protects projects downstream from delays and missteps.
Transforming laboratory recipes into commercial manufacturing does not follow a straight path. Cyclohexyl-containing intermediates sometimes throw unexpected challenges; one campaign last summer taught us that minute changes in stirring speed could impact byproduct formation. Solvent recovery plays a bigger role than many realize, both for cost control and for minimizing the trace contaminants that can sneak into product. The tanks, filters, and dryers holding Amino-Cyclohexyl-Acetic Acid require thorough cleaning to avoid trace amines or acids from prior use impacting current batches. We never let our cleaning records slip—a shortcut leads to headaches later.
In the fine chemical world, Amino-Cyclohexyl-Acetic Acid offers more than a link in a synthetic chain. Medicinal chemists value the cyclohexyl ring for its ability to introduce bulk and shape into bioactive molecules. It’s a simple tweak, but it affects how a molecule fits targets or evades metabolism. The amine and acid can anchor further modifications—amidation, esterification, coupling with diverse fragments. Our colleagues in polymer science use it to influence polymer flexibility and thermal stability. Plant biologists even test it in growth regulator work. Lab teams share stories with us about the hurdles of sourcing stable, reproducible starting materials; consistency from the factory makes the difference between a successful run or weeks of troubleshooting.
Others on the market offer Amino-Cyclohexyl-Acetic Acid, often by repackaging or reselling. We see the corners cut: variable melting points, cloudiness, or unpredictable pH in solution. Our product goes out only after passing spectral and chromatographic checks against authenticated standards. Granulation and particle sizing remain stable throughout storage; workers in the warehouse keep logs that track humidity and temperature to prevent hidden degradation. Shipments head out in moisture-barrier bags with internal protection against oxidation or hydrolysis. The bigger difference rests in aftersales support—when a client’s in scale-up trials and needs historical analysis or shelf-life documentation, we answer with real data accumulated over years, not textbook guesses.
Pharmaceutical projects can hinge on subtle chemical characteristics. A trusted partner in India once told us that a missed melting point range on our Amino-Cyclohexyl-Acetic Acid pushed back their project by a quarter. That lesson drove us to invest in more robust in-process controls and tighter release criteria. We value critical feedback—it keeps us honest and highlights how real-world conditions test theory. Synthetic chemists pushing a molecule through clinical evaluation care about every impurity profile and odor, not just paperwork. Frequent two-way communication matters; direct conversations help everyone adapt quickly rather than working from guesswork.
Incoming materials receive a full battery of identity and purity checks ahead of use. Finished product moves from stainless storage to sealed containers, minimizing air and moisture exposure. Workers log each lot with details on environmental exposure, date, and batch runner. We monitor warehouse climate using wireless sensors; extremes in summer humidity or winter dryness are flagged before product quality drifts. End users often call for advice on shelf life and storage. Our suggestions come from real experience: keep the drum sealed and cool; let it reach room temperature before opening to avoid condensation; never use scoops with residual acid or base. Stories of fouled batches or lost work trace back almost every time to ignored precautions.
Teams in our compliance division stay current on TSCA, REACH, and regional safety standards, but front-line operators also play their part. MSDS forms get routine updates whenever literature or field data add new findings. Each batch includes documentation that reflects not just composition, but also our observations on safe handling—even for rare cases where something unexpected popped up on a scale-up trial. Local safety officers tour our lines, and their input shapes process improvements. We don’t hide difficulties or treat regulatory needs as paperwork. Fewer surprises for us means fewer surprises for our partners.
Improvement comes not from big leaps, but from constant assessment. After each production campaign, our process and QA teams review performance, yield, and quality variation—not just from the current run, but by comparing against trends from previous years. Some differences link to shifts in raw material supplier; others stem from minor tweaks in SOPs. Every change is logged and referenced in future troubleshooting. Suggestions from customer labs—like tweaks to filtering or drying steps—feed back into our protocols. This culture of continuous improvement pushes us to challenge our complacency.
Markets demand more than a repeat of last year’s chemistry. Several research partners have reached out to explore novel derivatives based on the Amino-Cyclohexyl-Acetic Acid backbone. We retain both flexibility and technical rigor—small-scale glass reactors for pilot batches and kilo-scale vessels for semi-commercial production. Our chemists thrive on the chance to discuss possible analogues and new coupling routes. A recent partnership with a formulation lab resulted in a salt form with improved solubility for aqueous delivery. No single product line drives innovation, but having stable, trusted intermediates lets the entire lab focus attention on real breakthroughs.
We control sourcing of the core cyclohexylamines and monitor their purity well before they enter our reactors. Owning the manufacturing steps lets us respond quickly to new standards set by regulatory agencies or supply chain shifts. During broader solvent shortages, we built up internal recycling capacity, separating and purifying solvents for reuse. This structure not only decreases operational cost—it avoids sudden stoppages or batch variations that happen too often with spot-purchased raw materials. The team at our site knows the full sequence, from raw material gates to finished goods; any question along the way gets a hands-on answer.
Conversation strengthens understanding. Direct manufacturing brings us closer to researchers and production chemists. Every time we run a custom lot or accommodate a novel test specification, we learn what different industries value in an intermediate. University labs sometimes call to analyze odd analytical blips or unexplained color changes. These exchanges sharpen our process controls and provide early notice of emerging needs. We find pride in delivering batches that pass their high standards so that their research can move forward without error or delay.
Chemical production rarely moves smoothly. Interruptions in raw material supply happen. Energy costs shift, and environmental standards tighten. Tracking these variables comes from more than theoretical models; it needs hands-on experience with every piece of equipment. During last year’s power disruptions, our plant installed backup generators and reorganized maintenance so no batch risked degradation. Investment in filtration and analytical tools paid off every time a compound’s profile changed unexpectedly. Regulatory agencies add new hurdles, and our compliance leads keep daily watch so that documentation and safety measures always match current requirements.
The right outcome depends on people. We dedicate time to training new operators not just in theory but in real-world troubleshooting. Senior technicians walk fresh hires through equipment, explain the smells and observations that predict issues before they reach paperwork. Our site holds regular meetings where every team member—from maintenance to lab to shipping—shares the unexpected hiccups and victories of the week. No amount of automation replaces that shared experience. Building a team with long-term commitment drives down errors, prevents accidents, and upholds reputation far more than any single investment in machines or systems.
Emerging projects in pharmaceuticals or specialty materials demand quick adaptation. Recently, a customer asked for Amino-Cyclohexyl-Acetic Acid with an impurity profile narrower than any we had supplied. Our R&D crew rallied, reviewing chromatographic data and identifying process tweaks to eliminate troublesome side products. The finished lots matched the most demanding specs. Our ability to adapt on the fly draws directly from maintaining full oversight at every production stage. A field chemist or scale-up lab may not see the upstream effort, but their trust grows each time the product works exactly as intended.
As regulations evolve and awareness grows, we’ve shifted to more sustainable solvents, implemented energy-saving reactor controls, and taken steps to lower emissions from our plant. Our wastewater treatment system now captures and degrades trace organics released during purification steps. Worker suggestions led us to recapture heat and minimize losses. Each of these measures resulted in cleaner operation and less resource wastage. Clients sometimes ask for sustainability documentation; what they receive reflects the real investments from our site, not just abstract commitments. We believe improvements in process chemistry bring real value to the wider world.
Many can list the theoretical applications of Amino-Cyclohexyl-Acetic Acid. Having made it on a large scale, we know the surprises that don’t show up on a product sheet. Water control at the final crystallization makes or breaks phase purity. Handling practices on the warehouse floor influence shelf life more than most realize. Reliable supply supports confidence in even the most complicated syntheses. Our approach always draws on lessons learned batch after batch, season after season, rather than relying solely on textbook theory.
Direct engagement in manufacturing means standing behind each lot of Amino-Cyclohexyl-Acetic Acid with both technical expertise and practical experience. Every success and setback shapes future runs and builds stronger understanding. Partners relying on stable, clean intermediates to power innovation find assurance in the details we oversee from the inside. By owning the process and listening to the end user, we help better science happen every day.