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Allyl Chloroacetate

    • Product Name Allyl Chloroacetate
    • Alias Chloroacetic acid allyl ester
    • Einecs 214-470-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    524166

    Cas Number 6315-59-1
    Molecular Formula C5H7ClO2
    Molecular Weight 134.56 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 163-164 °C
    Melting Point -82 °C
    Density 1.119 g/mL at 25 °C
    Flash Point 55 °C (closed cup)
    Refractive Index 1.445-1.448 at 20 °C
    Solubility In Water Decomposes
    Vapor Pressure 0.4 mmHg at 20 °C
    Purity Typically ≥98%

    As an accredited Allyl Chloroacetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Allyl Chloroacetate, 500 mL, packaged in a sealed amber glass bottle with tight screw cap and hazard labeling for safety.
    Shipping **Allyl Chloroacetate** is shipped as a hazardous chemical. Packaging must comply with international and national regulations, often in tightly sealed containers to prevent leaks and exposure. It should be labeled appropriately, transported under controlled conditions, and accompanied by safety documentation, including SDS and shipping papers, to ensure safe handling and delivery.
    Storage Allyl Chloroacetate should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers. Keep the container tightly closed and protected from moisture. Store in a secure area designed for flammable liquids and corrosive substances, with appropriate chemical labeling and spill containment measures in place.
    Application of Allyl Chloroacetate

    Applications of Allyl Chloroacetate in Industrial Manufacturing

    Allyl chloroacetate serves as a strategic intermediate for multiple chemical industries, enabling the synthesis of specialized compounds through precise downstream integration. Below are focused application scenarios where this chemical demonstrates essential value in manufacturing environments driven by strict regulatory, formulation, and process imperatives.

    1. Synthesis of Pharmaceutical Active Intermediates

    In pharmaceutical manufacturing, production lines utilize allyl chloroacetate as a reactive intermediate during the preparation of select β-lactam antibiotics and heterocyclic building blocks. The material enters alkylation or esterification steps, conferring specific functionalities required for further medicinal chemistry transformations. Maintaining precise dosing and quality parameters is critical due to the downstream influence on API purity and batch reproducibility, especially when scaling under cGMP environments targeting regulated pharma markets.

    Industry compliance standards

    • ICH Q7 GMP Guidelines for Active Pharmaceutical Ingredients
    • Pharmacopeia (USP, EP, JP) impurity and residual solvent limits
    • FDA 21 CFR Part 211 (cGMP for Finished Pharmaceuticals)
    • REACH Regulation (EC) No 1907/2006 (import and usage of intermediates)

    Typical usage ratio

    • 0.8–3.5 mol equivalents relative to the nucleophile or amine reactant; ratio adjusted according to target intermediate yield and residual purification constraints

    Downstream process integration

    • Dosed during nucleophilic substitution or esterification steps within multi-step reaction trains for antibiotic or heterocyclic compound assembly

    Final product types

    • Pharmaceutical precursors for β-lactam antibiotics
    • Active pharmaceutical ingredient intermediates
    • Chemical probes for medicinal chemistry research
    • Advanced building blocks for custom synthesis services

    2. Agrochemical Intermediate Production

    Agrochemical manufacturers deploy allyl chloroacetate for synthesizing ester and ether building blocks essential in formulating modern insecticides, herbicides, and fungicidal actives. Its application centers on chloromethylation or allylation protocols, where precise handling ensures compatibility with advanced continuous processing units and compliance with agrochem-specific health and environmental standards. Batch control and traceability form vital elements in ensuring regulatory acceptance throughout the agrochemical supply chain.

    Industry compliance standards

    • FAO/WHO Technical Specifications for Pesticides
    • ISO 9001:2015 Quality Management Systems
    • OECD Guidelines for the Testing of Chemicals (Residues in food and environment)
    • Globally Harmonized System of Classification and Labelling of Chemicals (GHS)

    Typical usage ratio

    • 1.0–2.2 mol equivalents depending on target ester yield and the structural requirement of the active compound

    Downstream process integration

    • Introduced at methylation or allylation steps during active ingredient assembly in batch or flow reactors

    Final product types

    • Key intermediates for synthetic pyrethroids
    • Building blocks for herbicidal esters
    • Precursors to fungicidal ether derivatives
    • Agrochemical actives assembled for premix and technical concentrate formulations

    3. Fragrance and Flavor Ester Manufacturing

    Specialty aroma and flavor houses rely on allyl chloroacetate in the production of complex esters imparting unique green, fruity, or spicy notes in fine perfumery and flavor compositions. Here, the raw material’s addition must be tightly regulated due to sensory and food-grade constraints, and all production stages adhere to rigorous quality testing for trace contaminants. Process engineers monitor each esterification lot for backend food compliance and low-odor thresholds tailored to fragrance compound deployment.

    Industry compliance standards

    • IFRA Code of Practice (International Fragrance Association)
    • FCC (Food Chemicals Codex) limits if used in flavor ingredients
    • EU Regulation (EC) No 1334/2008 on flavorings and certain food ingredients
    • ISO 9001:2015 for quality traceability in aroma production

    Typical usage ratio

    • 0.5–2% by weight in reaction blends, modified by ester target purity and desired sensorial impact

    Downstream process integration

    • Added in batch reactor esterification or transesterification steps for fragrance or flavor ester development

    Final product types

    • Green note esters for fine fragrance bases
    • Flavor esters used in beverage and confection formulations
    • Chemical intermediates for proprietary aroma compounds
    • Bulk fragrance molecules for industrial perfume blending

    4. Polymer and Resin Modifier Synthesis

    Advanced material producers introduce allyl chloroacetate to synthesize side-chain functional monomers and specialty polymer modifiers, with a focus on resins requiring tailored reactivity or crosslink density. The controlled incorporation affects final product performance such as adhesion, flexibility, or weatherability, thus dosing and polymerization sequence remain tightly regulated. Integration occurs before or during emulsion or bulk polymerization, and all production aligns with chemical safety and environmental discharge controls relevant to region and downstream use.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management Systems
    • REACH Regulation for polymer precursors
    • RoHS Directive (if intended for electronics/electrical applications)
    • ASTM Standard D256 for plastics impact resistance (where applicable to end use)

    Typical usage ratio

    • 0.3–1.8 mol% relative to the main monomer batch, selected to balance downstream mechanical and chemical properties

    Downstream process integration

    • Fed into pre-polymerization or post-polymer functionalization lines for specialty resin or copolymer manufacture

    Final product types

    • Chemically modified acrylic resins
    • Alkyd or polyester resin systems with enhanced adhesion
    • Functionalized copolymers for adhesives or coatings
    • Specialty plastics engineered for automotive or construction applications

    5. Fine Organic Synthesis for Specialty Chemicals

    Chemical manufacturers leverage allyl chloroacetate as a precursor in constructing advanced intermediates for specialty production, especially in high-value fine chemicals requiring selective chlorination or allylation. Downstream handling involves precision dosing to regulate functional group transfer and minimize byproduct formation, especially in pilot-scale or toll manufacturing settings where quality control determines acceptability for subsequent conversion. Safety, transport, and storage must also meet heightened requirements due to inherent reactivity at each synthesis scale.

    Industry compliance standards

    • OECD Good Laboratory Practice (GLP) for purity and safety data
    • UN ADR for Classification and Packaging of Dangerous Goods
    • Responsible Care® chemical stewardship protocols
    • QC procedures according to ISO 17025 laboratory standards

    Typical usage ratio

    • 1.0–2.5 mol equivalents aligned with the target transformation and desired conversion rate; re-optimized for scale-up efficiency or custom customer specifications

    Downstream process integration

    • Employed in fine chemical synthesis steps requiring alkyl, chloroacetyl, or allyl group introduction, often via batch or semi-batch reactor setups

    Final product types

    • Specialized carboxylic acid derivatives
    • Functional esters for industrial synthesis
    • Allyl and chloromethyl building blocks for research and development
    • Intermediate chemicals for further downstream transformation in contract manufacturing
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    Certification & Compliance
    More Introduction

    Allyl Chloroacetate: Direct from the Manufacturer’s Line

    Introducing Our Allyl Chloroacetate

    Producing specialty chemicals has always demanded both precision and flexibility, and Allyl Chloroacetate stands out as a case where technique and reliability shape every stage of the process. Across decades on the production floor, the unique requirements of chloroacetates have driven us to develop tight controls, specific purification steps, and approaches that differ from both simple esters and heavier chlorinated intermediates.

    Choosing Allyl Chloroacetate from a manufacturer’s perspective means ensuring product uniformity, but also fielding tough questions from R&D labs, procurement agents, and scale-up managers. Every quality checkpoint reflects lessons learned batch after batch—during reactor maintenance, quality audits, and customer feedback loops. Our team works with upstream suppliers to verify raw ingredient purity. Operators tune reaction conditions, monitor pressure and temperature, and sample for downstream analysis. Each drum carries the traceable proof.

    How Allyl Chloroacetate Takes Shape in Manufacturing

    We don’t approach this molecule like a commodity. Every order reflects planning that starts at the basic chemistry, runs through risk assessments, and carries through to packaging and logistics. Allyl Chloroacetate production revolves around the esterification of chloroacetic acid with allyl alcohol under anhydrous conditions. Here, the practical value centers on tight temperature control: too hot, and by-products form or yields drop; too low, and conversion suffers. This hands-on balance is where operator knowledge beats automation.

    Our best batches come from teams that respect this chemistry—people who know what a clean downstream cut looks and smells like. Physical properties stand as a testament to this care: a clear, colorless liquid, boiling point hovering in the 180°C range, distinctive pungent odor. Trace water content and residual acids can alter performance in synthesis, so every shipment passes moisture and purity checks.

    Specifications aren’t just a certificate to us. Each figure—whether it’s percent purity or acid value—ties to decisions made by our chemists, operators, and quality team. Technical specs by themselves don’t determine fitness for use, but in our experience, most customers rely on 98%+ purity, minimal acid residue, and packaging that maintains shelf-stability.

    Application Experience and Customer Feedback

    Across the chemical world, Allyl Chloroacetate has carved its spot as a valued building block—its allyl group opens up a spectrum of transformations. The most common feedback we receive highlights three areas: reactivity in esterification and etherification, performance in specialty polymer curing, and utility as an intermediate in pharmaceuticals and agrochemicals.

    Researchers and process chemists often ask about its use in crafting allyl-functional acrylics, custom resins, and chemical linkers. We’ve seen creative adaptations outside classic textbooks—one customer leveraged its unique reactivity to design soft monomers for adhesives. In life sciences, the molecule sometimes serves as a masked delivery group, cleaved in later steps to unlock new active ingredients.

    Users value tight specs not as checkboxes, but because excess free acid or residual water has real consequences: yield loss, gelation, unwanted side-reactions. Product consistency, as measured by NMR and gas chromatography, directly affects how our customers scale new syntheses, register new substances, and develop innovative coatings or biocides.

    What Sets Allyl Chloroacetate Apart from Similar Products

    The chemistry world offers plenty of chloroacetates and plant-based esters—ethyl, methyl, and butyl varieties fill shelves, each with slightly different handling and application quirks. Allyl Chloroacetate differs in reactivity: its allyl group invites nucleophilic addition and radical polymerization, expanding its synthetic possibilities far beyond what methyl and ethyl versions allow. Our experience handling both standard acetates and their allylated cousins shows that only Allyl Chloroacetate enables certain functionalizations at reasonable temperatures and without complex protecting groups.

    There’s also a handling angle: compared to lower esters, Allyl Chloroacetate volatilizes less quickly, which changes storage and workplace requirements. Its odor—sharp and characteristic—helps operators detect leaks at low concentrations. We design our packaging and labeling with these properties in mind.

    Other chloroacetates can sub in for less demanding syntheses, but only Allyl Chloroacetate supports the allylation steps necessary in specialty intermediates. After years of customer sampling and scale-up runs, requests for substitutions always lead back to this core property: the allyl group slots into polymer, active pharmaceutical, and fine chemical scaffolds where nothing else fits.

    Quality and Consistency Are Built In

    Every batch of Allyl Chloroacetate that leaves our facility represents a controlled process. The difference shows up not in paperwork, but in how our product behaves in a customer’s flask. Our team doesn’t rely on spot checks alone. They run full profiles on selected lots, track physical and chemical property trends over time, and troubleshoot quickly when deviations appear.

    If product color drifts from water-white or faintly straw, we investigate upstream sources and see if catalysts need adjustment. Experience tells us customers reject even minor discoloration in API work or optical applications. Similarly, byproduct formation—such as diallyl ethers—means catalyst tweaking or more precise water removal upstream. Our plant engineers and shift chemists keep close watch on each stage, informed by years on the floor and feedback from customers mixing our product in their glassware.

    Customer audits have shaped our routine. We understand what it means to supply an input for a pilot medicine, or a resin batch running all weekend with only a few kilograms of critical feedstock. We keep archived samples, trend impurity levels, and prepare transparent quality dossiers. Every improvement made here reflects the reality of industrial and specialty use: process flows don’t pause for subpar feedstock.

    Real-World Experience with Shipping and Handling

    Transporting reactive chemicals across borders brings practical challenges that only come clear with experience. Moisture ingress, thermal instability in transit, fluctuations of storage temperature—these don’t show up in brochures, but hit reliability hard. We’ve adapted our drum and IBC container choices over years, fine-tuning closures and headspaces to manage pressure buildup, prevent leaks, and eliminate spoilage before it starts.

    Working directly with regional warehouses means our own teams verify storage conditions. Site visits have shown us issues that paperwork could miss—such as sunlight exposure on loading docks, or unventilated storage rooms. We’ve written our handling protocols to match these realities. Requests for small-pack samples or custom labeling come through our own plant team, not a remote third party, extending our QC mindset into the field.

    We train our logistics partners on clean handling—drums remain sealed until use, and emptied containers pass through waste streams with full traceability. Each return shipment prompts an investigation. Over the years, these steps have cut spoilage losses and supported cleaner audits for all parties.

    Regulatory and Safety Perspectives

    Owning the entire production and compliance pathway means constant attention to regulatory shifts. The handling of allyl-functional chlorinated esters—especially for customers making intermediates used in pharmaceutical or crop-protection products—requires ongoing documentation. Our regulatory team reviews regional chemical inventories, safety data, exposure scenarios, and waste codes.

    We handle regular customer requests seeking purity statements, contaminant quantification, and tox data. Product stewardship shapes every batch. From initial process safety reviews right through to customer handling advice, we opt for transparency: MSDS, GHS labeling, and ADR-compliant transport. The expertise here comes not from manuals, but from many years answering auditor and customer queries and adapting operations as the regulatory environment evolves.

    Safe use depends on truthful, experience-based hazard communication. The pungent odor, moderate volatility, and potential for skin sensitivity demand ventilation and secure gloves. Regular in-plant drills and exposure monitoring protect our own teams before anything leaves the gate.

    Continuous Improvement Driven by Use Cases

    The best product improvements never start with internal wish lists alone. They grow from conversations with users—face-to-face at trade events, over the phone troubleshooting trial batches, or on-site solving scale-up problems. We treat every out-of-spec experience as a learning point, running root-cause analyses that sometimes lead to process upgrades. Adjustments to reactor design, new purification equipment, or modified packaging formats have stemmed directly from needs expressed by research chemists and operations leads.

    Scaling new syntheses often pushes our process to its limits. The odd polymerization run, or a problem with downstream crystallization, has prompted us to rethink solvent choices, tweak drying protocols, or collaborate with customer QC labs to interpret analytical puzzles. Our R&D team remains on standby—solutions drawn from plant-floor experience, industry dialogue, and trend monitoring.

    Regular technical exchanges with end-users inspire confidence and foster innovation. If a customer finds a new application for Allyl Chloroacetate—perhaps as an initiator in radical grafting, or for targeted protection strategies—we work to validate their needs, supporting with analytical data or samples designed for real-world R&D.

    Challenges We Face—And How We Respond

    No chemical plant escapes the unexpected. Power outages, off-spec raw materials, shifts in regulatory regimes—all these test our resilience. We’ve faced shortages in key precursors, and rather than freeze production, we’ve built up dual-qualified supply chains, stockpiled strategic inputs, and invested in storage. Raw material price surges challenged us to rethink procurement and forecasting, passing stability on to customers wherever feasible.

    On the technical front, unexpected color shifts or odor issues have forced us to refine our purification cycles or identify trace contaminants. Each investigation translates into new monitoring routines—spot-checks or inline coding to catch drift early. If purity dips, we revisit washing sequences. If byproducts appear, process conditions get reviewed with fresh eyes. Our laboratory staff, trained in practical troubleshooting, keeps close records, enabling timeline-based root-cause searches when needed.

    Some challenges stem from downstream product uses we could never predict. It’s not always possible to control for every reaction variable once Allyl Chloroacetate leaves our plant, but we offer process guidance or technical support where we can. Case studies drawn from real customer issues help us craft more relevant data packages for the next project.

    Environmental Responsibility and Waste Management

    Waste minimization has grown into a non-negotiable part of our operations. Chloroacetate streams, especially those carrying unreacted feeds or offcuts, move through in-plant recovery units and external waste treatment. We optimize each step: distillation, neutralization, and solvent recovery support clean water and air goals across the site.

    Local regulators partner with us to audit emissions and site practices. Zero-discharge water handling and energy-efficient distillation didn’t come from overnight upgrades—they reflect years of incremental investments as expectations shifted. Customer interest in sustainable inputs has prompted us to review both feedstock sourcing and manufacturing energy profiles. Each environmental improvement we make feeds back into product reliability—no one wants a batch delayed because of a permit hold or out-of-tolerance emission.

    Downstream users also benefit from our knowledge of safe disposal and recycling options for Allyl Chloroacetate. Sharing waste-handling best practices has closed the loop on small-scale testing and legacy projects, supporting a cleaner approach to specialty chemical work.

    Working With Our Customers

    Being a direct manufacturer means we answer every inquiry ourselves. Customers rely on us for not just quality, but technical and regulatory support shaped by years on the ground. We see ourselves as problem-solvers, working alongside each R&D lab or production crew sourcing Allyl Chloroacetate. Our product goes out carefully labeled, securely packaged, and backed by technical data drawn from real plant data—not recycled boilerplate or third-hand claims.

    For customers developing new reactions or scaling up formulations, we share analytical insights and process tips. Our chemists can usually recommend conditions that avoid common pitfalls, and troubleshoot both pilot and commercial batch runs. End-users benefit from our open-door policy on samples, technical clarifications, and process change requests.

    Total transparency, earned from decades of direct production, means we can speak plainly about risks, solutions, and best practices. The relationship doesn’t end at shipment. For us, successful supply means ongoing engagement and shared problem-solving as markets and needs evolve.

    Conclusion: Why Direct Manufacturing Matters for Allyl Chloroacetate

    Decades of experience producing Allyl Chloroacetate have taught us that every molecule on the market reflects the care, skill, and integrity of its maker. As chemical complexity grows, reliability matters more than ever. Direct manufacturing connects customer needs to process realities, closes the loop between feedback and improvement, and keeps both parties at the center of innovation.

    By controlling production from start to finish, responding to real-world customer challenges, and focusing on practical quality and safety, we’ve built an Allyl Chloroacetate supply that R&D chemists, plant engineers, and business partners trust. Our plant’s output isn’t just stock—it’s the result of continuous teamwork, technical expertise, and relentless attention to detail for every drum that ships.