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Adrenosterone

    • Product Name Adrenosterone
    • Alias 11-oxo-androstenedione
    • Einecs 206-564-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    816324

    Chemical Name Adrenosterone
    Synonyms 11-oxoandrostenedione
    Molecular Formula C19H24O3
    Molecular Weight 300.39 g/mol
    Cas Number 382-45-6
    Appearance White crystalline powder
    Solubility Slightly soluble in water, soluble in ethanol and chloroform
    Melting Point 180-182°C
    Usage Dietary supplement, bodybuilding
    Mechanism Of Action Inhibits cortisol, weakly androgenic
    Half Life Unknown in humans
    Legal Status Varies by country, often unregulated as a supplement

    As an accredited Adrenosterone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Adrenosterone is supplied in a white, sealed HDPE bottle containing 5 grams, labeled with product name, purity, and safety information.
    Shipping Adrenosterone is shipped in compliance with chemical safety regulations. It is securely packaged in sealed containers to prevent contamination or leakage. All packages include appropriate labeling, documentation, and hazard information. Shipping is typically via ground or air transport, depending on destination, and only to authorized facilities with proper handling certification.
    Storage Adrenosterone should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry place, ideally at 2-8°C (refrigerator temperature), and away from incompatible substances such as strong oxidizers. Ensure proper labeling and restrict access to authorized personnel only. Follow local regulations and safety guidelines for chemical storage and handling.
    Application of Adrenosterone

    Applications of Adrenosterone in Industrial Manufacturing

    Adrenosterone serves as a specialty chemical intermediate in several regulated manufacturing sectors. As a dedicated chemical raw material producer, we supply adrenosterone in high purity for integration into downstream industrial processes. Below are the verified application scenarios with specific operational, compliance, and technical details.

    1. Pharmaceutical API Intermediate for Steroidal Drug Synthesis

    Leading pharmaceutical manufacturers employ adrenosterone as a key intermediate for synthesizing various corticosteroid and androgen-modulating APIs. Production batches must adhere to Good Manufacturing Practices (GMP). Operators incorporate adrenosterone within multistep syntheses of glucocorticoid and antiandrogen pharmaceuticals. The precise usage ratio depends on the target API but typically follows stoichiometry within accepted ranges for FDA or EMA-approved formulations. Batch records must document sourcing, purity, and traceability from the first reaction onward, ensuring uniformity through in-process controls and validated methods until active pharmaceutical ingredients are isolated and purified.

    Industry compliance standards

    • Current Good Manufacturing Practices (cGMP, 21 CFR Parts 210/211)
    • European Pharmacopoeia (Ph. Eur.) monographs on steroids
    • US FDA guidelines for API manufacturing
    • International Conference on Harmonisation Q7 (ICH Q7)

    Typical usage ratio

    • 0.10 to 0.35 molar equivalents, adjusted per API synthesis pathway
    • Exact weight ratios set following reaction stoichiometry and specific target molecule
    • Pilot batches establish scale-up equivalence
    • In-process controls determine the actual charge based on precursor purity and yield requirements

    Downstream process integration

    • Introduced after primary extraction or purification of starting materials
    • Engaged in key steroid nucleus modification steps via reduction, oxidation, or esterification
    • Monitored by HPLC and GC-MS throughout synthesis
    • Purified, filtered, and isolated prior to final API crystallization and compounding

    Final product types

    • Methylprednisolone raw API
    • Prednisolone acetate raw API
    • Corticosteroid bulk drugs for solid and injectable dosage forms
    • Adrenal modulator intermediates for hormonal therapy preparations

    2. Reference Standard and Analytical Reagent Supplier to Contract Laboratories

    Analytical, clinical, and quality control laboratories deploy adrenosterone as a certified reference standard for steroid quantification and impurity profiling. The material requires validated purity assays, with documented storage and handling protocols. Laboratories depend on consistent, lot-specific reference values for calibration in mass spectrometry and chromatographic methods. Our manufacturing controls include traceable COAs and impurity profiles aligned with industry-standard analytical dosing protocols.

    Industry compliance standards

    • ISO 17034 for reference material producers
    • ISO/IEC 17025 laboratory accreditation
    • USP Reference Standards Guidance
    • European Pharmacopoeia requirements for secondary standards

    Typical usage ratio

    • 1–10 mg per analytical run
    • Calibration solutions typically prepared at 0.1–100 µg/mL in appropriate solvents
    • Reconstitution concentration determined by detection method and quantitation limits
    • Aliquot size tailored to laboratory assay protocol and instrument sensitivity

    Downstream process integration

    • Reconstituted as calibration standards for HPLC, GC-MS, or LC-MS/MS analysis
    • Deployed in method validation, impurity testing, and routine batch release
    • Certified material issued to QC teams for performance verification
    • Referenced in COA/QC approval for pharmaceutical and supplement lots

    Final product types

    • Certified reference material kits for external QA programs
    • Calibration solution vials for pharmaceutical laboratories
    • Extracted biological samples for steroid panel analysis
    • QC release test result reports for regulated manufacturing batches

    3. Precursor Material for Veterinary Glucocorticoid Product Formulation

    Veterinary pharmaceutical companies leverage adrenosterone as a precursor in the controlled synthesis of glucocorticoid agents for animal health management. Production lines integrate the material during specific transformation steps to yield finished APIs under VICH and regional animal drug regulations. Rigorous in-process testing validates conversion rates and controls residual precursor content. The raw material charge is defined by target batch size, animal species, and regulatory dose standards, with technical protocols adjusting input levels to ensure compliance in final veterinary formulations.

    Industry compliance standards

    • Veterinary International Cooperation on Harmonisation (VICH GLs)
    • US FDA Center for Veterinary Medicine (CVM) Guidance
    • EU Regulation No 2019/6 for veterinary medicinal products
    • Global GAP principles for animal health APIs

    Typical usage ratio

    • 0.15–0.40 molar equivalents per synthetic cycle, based on targeted corticosteroid API output
    • Ratios may vary according to specific veterinary species requirements
    • Adjustment based on in-process reaction yields and finished product specifications
    • Account for scalability to commercial animal health product batch sizes

    Downstream process integration

    • Processed in initial reaction vessel as starting material for steroid nucleus functionalization
    • Subjected to animal-drug-specific purification protocols
    • Monitored in laboratory synthesis and pilot scale-up for compliance with residue criteria
    • Converted into active ingredients for veterinary injectable and oral dosage forms

    Final product types

    • Corticosteroid anti-inflammatory preparations for cattle, swine, and equine
    • Veterinary medicated feed additives containing corticosteroid APIs
    • Oral and injectable veterinary pharmaceuticals
    • Glucocorticoid compositions for animal dermatological and joint therapies

    4. Research Chemical Supply for Academic Steroid Metabolism Studies

    Academic and commercial research groups order adrenosterone as a research chemical for enzymatic pathway investigation, receptor binding filtration, and model organism metabolism research in steroid biochemistry. Research supply lots ship with full analytical documentation and MSDS in compliance with university procurement guidelines. Scientists may adjust working concentration depending on study design, enzyme source, or experimental model, with precise delivery ensured by direct manufacturer supply and institutional chain-of-custody policies.

    Industry compliance standards

    • Institutional Biosafety Committee (IBC) risk assessment
    • UN Globally Harmonized System (GHS) labeling for research chemicals
    • National Institutes of Health (NIH) guidelines for laboratory chemical safety
    • OECD Good Laboratory Practice (GLP) principles for nonclinical studies

    Typical usage ratio

    • 10–100 µM in cell culture or enzyme incubation
    • 10–500 mg per animal model, case-dependent on protocol
    • Freshly prepared working solutions for every experiment to maintain stability
    • Stock concentrations based on solubility and research application

    Downstream process integration

    • Diluted in buffer systems for use as substrate or inhibitor in enzymatic assays
    • Administered in animal models for pharmacokinetics and metabolism studies
    • Applied in molecular screening platforms for target engagement analysis
    • Sampled by LC-MS or NMR to quantify conversion and analyze metabolic fate

    Final product types

    • Data sets on steroid metabolic pathways
    • Published academic studies on enzyme selectivity and specificity
    • Validated assay protocols for drug discovery research
    • Reference samples for further steroid biosynthesis and transformation
    Free Quote

    Competitive Adrenosterone prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Adrenosterone: Precision, Consistency, and Our Commitment to Quality

    Understanding Adrenosterone from the Manufacturer's Perspective

    Decades in the fine chemical business have taught us the difference between a batch that passes and a batch that inspires confidence. With adrenosterone, that line becomes razor sharp. We see this molecule come off our reactors and crystalize under controlled conditions each production run, and every time, its value—real, practical, measurable—reaffirms why reliable chemistry is at the core of scientific progress.

    We built our process for adrenosterone on two core principles: purity and consistency. Customers ranging from research labs to pilot-scale pharmaceutical projects count on this specific steroid to arrive as promised, with specifications true to what’s on our COA. Our technical team measures each lot using HPLC, NMR, and mass spectrometry to confirm that stringent standards are met, not just once, but every time. We understand first-hand how a single result outside the specification can set back months of work, and we do not let that happen.

    The Chemistry that Shapes Real-World Results

    Adrenosterone, known structurally as 11-oxo-androstenedione, is unique in its functional group positioning, giving it a decisive edge in several research and industrial settings. We produce it as a pale crystalline powder, optimized for both chemical stability and precise measurement. After years of process refinement, we maintain low impurity content and finely controlled particle size. These factors are talked about in textbooks, but they show up in the lab as higher yields, clearer endpoint analysis, and reliable reactivity.

    Not every supplier can say they know the feel of a freshly milled batch or the subtle color differences when humidity creeps into a drying room. We take batch-to-batch consistency seriously because reliable chemistry doesn’t happen in a vacuum. Our QC staff runs dozens of purity checks and reports any deviation—not to pad paperwork, but because customers expect the same molecule, every shipment, all year long. Researchers working on steroid biosynthesis, enzyme inhibition studies, or technical development projects notice these differences fast.

    Specifications and Traits That Matter in Daily Use

    From a user’s standpoint, what matters most is how seamlessly a substance integrates into existing workstreams. Adrenosterone in our lineup typically ships at 99% or better HPLC purity, with residual solvents and any related steroids held far below regulatory thresholds. While some competitors may quote similar numbers, the lived experience of handling a powder free from clumps and loaded with assay transparency can’t be overstated. Less time scraping sticky residues from flasks, fewer strange peaks in analytical traces—our partners report these benefits directly.

    We don’t believe in advertising theoretical performance. We observe adrenosterone through all the practical metrics that matter: solubility in common organic solvents, shelf stability, safe and secure packaging, and ease of handling under standard lab conditions. We only ship after performing extended stability tests in climatic chambers, pushing the product through real-world temperature and humidity cycles. This is not about documentation—this is about making life easier for customers.

    Field experience shows that adrenosterone holds its integrity through the full manufacturer-to-lab pipeline. No off odors, no signs of breakdown, no weird discoloration after a few weeks on the shelf. These details show up in user experience surveys and direct feedback. A customer’s workflow either proceeds smoothly or loses hours; we make straight paths possible.

    Direct Manufacturer Insights: Safety and Handling

    Safety in chemical manufacturing is never theoretical. All staff on our lines go through ongoing hazard training. We invest in engineered containment, dust control, and fail-safe protocols not just to meet requirements, but to give us confidence when we stand behind our batches. Our plant runs routine reviews of exposure controls and spill response drills. Adrenosterone production doesn’t leave room for shortcuts.

    Lab users benefit from these upstream decisions. Clean batches arrive because we take the time to minimize potential for operator exposure, cross-contamination, and packaging failures. Reconstitution in solvent works as the literature states, and the powder behaves the same each time, which saves operators frustration and guarantees project reproducibility. Safety data is actionable and written for real users, not regulatory boxes.

    Applications: From Bench Chemistry to Bench-to-Bedside Translations

    Our experience shows adrenosterone commonly goes into research involving steroid receptor biology, endocrine system modeling, and enzyme pathway investigations. Teams in both academia and industry choose this compound due to its clear pathway to dihydrotestosterone analogs, along with the manageable side chain reactivity that offers creative latitude for synthesis. Many biochemistry labs employ our material in radiolabeling work, because predictable reactivity cuts down troubleshooting and increases the odds of meaningful data.

    Postdoctoral fellows and professors have told us about breakthroughs where a reliable supply chain for adrenosterone enabled multi-step reactions that otherwise faced constant disruption. Some work directly on enzyme modulation, others on metabolic pathway tracing. These successes don’t materialize unless the molecule is the same every time. We cannot count the number of times a research group has switched from unbranded bulk sources and reported improvements in reaction clarity and yield.

    Differences From Other Products: Beyond the Sales Pitch

    Being a manufacturer makes one thing clear—no two sources deliver the same experience, even if the CAS numbers line up. Adrenosterone is often compared to other steroidal intermediates, like androstendione or 11β-hydroxyandrostendione. The technical line between these compounds can look superficial on paper, but in a lab or production setting, the functional differences steer entire research agendas. Our adrenosterone batch consistently offers sharper melting point ranges, delivers processable stability under ambient conditions, and avoids unwanted by-products that complicate downstream derivatization.

    Feedback from process chemists tells us that byproducts aren’t merely a nuisance; they can derail projects by causing false positives in biological screens or unpredictable bioactivity in cell assays. Some competitors sell material with higher water content, or with traces of starting materials that slip through less rigorous purification sequences. Through hands-on chromatography work and multiple fractionation passes, we remove these confounding factors, so our users get precisely what their research demands, with fewer headaches and no guesswork.

    Several pharmaceutical partners also point to our transparency in documentation—every batch comes with a complete analytical dataset, not just a passing certificate. This habit stems from hard-won experience; our customers appreciate being able to review, challenge, and discuss real trace chromatographs and spectra without waiting days for a response. The direct back-and-forth makes complex synthesis projects actually feasible.

    Trust Built on Experience—Not Vendor Branding

    Trust in this business is rarely built by a website or a glossy brochure. Chemists choose their sources based on reputation, speed of technical support, and truth in labeling. We’ve grown with customers who keep asking for more data, more detailed chromatography, and more proof of process stability. That doesn’t threaten us—it motivates us. Being a direct manufacturer means fully owning every drum and every gram that leaves our facility. This mindset breeds accountability and a willingness to invest in constant process improvement.

    We do not chase the lowest cost or look for ways to cut corners on purification times. Every minute that goes into batch preparation, every hour in a stability oven, every extra QC check is time earned back by our customers with fewer failed syntheses, fewer unexplained peaks, and more confidence that a repeat order will behave exactly the same as the last. Our philosophy stands in contrast with traders or aggregators who rarely see the inside of a reactor or handle the product beyond palletizing.

    Years of direct feedback and audit visits from partners, both big and small, show us the value of open doors. We regularly invite technical clients to inspect our process controls and documentation chain. Our account managers know the shop floor—and the challenges customers actually face—because they spend as much time in plant meetings as on sales calls. This practical knowledge flows into every aspect of our offering.

    Quality Control: More Than Regulatory Box-Ticking

    Any manufacturer of adrenosterone can show compliance paperwork, but true quality assurance grows from stubborn attention to detail. The path from raw input to packed product takes us through dozens of opportunities for error, and our role is to eliminate each through training, equipment upgrades, and knowledge sharing. Every operator learns what drift in the crystallization point looks like—and also gets the authority to put a halt on any suspect batch. We have rejected hundreds of kilograms rather than risk the customer’s trust.

    On the technical side, the use of advanced analytics, such as high-resolution NMR and LC-MS, helps us pick up even minute variances in chemical profile. Not all labs sort between polymorphic forms or run extended stability under simulated shipping stress conditions. We do, because international customers have lost too many shipments to unseen climate challenges, and they don’t want to be surprised with degraded material. Our philosophy is simple: fewer excuses, more usable product.

    Packaging and Delivery: The Hidden Details That Rescue Projects

    One thing experienced manufacturers notice—packaging shapes chemistry as much as glassware selection. We select containers for adrenosterone based on barrier performance, absence of static charge, and ease of opening at the bench. A drop in humidity control, a poorly-sealed lid, or a flawed liner can undo weeks of careful synthesis in the plant. We vacuum-seal and overpack every shipment, with tamper-proof closures and full traceability back to final QC sign-off.

    We listen when customers report problems with clumping, static attraction, or caked powder at the bottom of tubes. Our process lab explores alternate antistatic agents and loader techniques, improving results batch over batch. These tweaks look small, but in a competition for every decimal point in yield, every unneeded transfer step, or every misweighed aliquot can matter. That’s why we focus as much on the afterlife of our product as on its initial synthesis.

    Supporting Diverse Innovation Through Robust Supply Chains

    Production of adrenosterone scales from pilot to metric ton volumes, and we never gamble on just-in-time inventory. We maintain staged supplies of critical raw materials and manage upstream vendor relationships with the same care we offer our direct customers. Planning for raw material disruptions or unpredictable regulatory delays has kept our clients’ projects on schedule through multiple supply chain crises. Our focus on forward contracts and dual sourcing for critical precursors allows us to guarantee availability even as regional trade landscapes shift.

    One strength of our approach—a well-maintained stock buffer and direct QC signoff for every outgoing package. We communicate openly with customers about lead times, never hiding behind automated replies. Delays happen, but in this business, a half-day communication advantage on a delayed batch or an alternative sourcing solution makes all the difference for a team planning time-sensitive assays or production campaigns.

    Some clients work in regulated pharmaceutical spaces, others in more agile biotech settings. We adapt to both, with processes transparent enough to satisfy full batch record requests while staying nimble for exploratory R&D orders. Our manufacturing logs are accessible, our support grounded in real-world chemical challenges, and our team trained to anticipate needs before they result in delays.

    Adrenosterone Moving Forward: Futureproofing with Knowledge and Accountability

    Looking at the broader fine chemical sector, waves of regulatory, environmental, and logistical challenges continue to reshape priorities and timelines. We treat compliance updates as opportunities to rethink process safety and emission standards rather than obligations to check off. Our engineers have retrofitted several plant modules to meet environmental expectations, such as stricter VOC emission controls and more rigorous wastewater management. Each upgrade comes after direct consultation with technical clients who want both assurance and transparency regarding the products they use in downstream therapeutic or diagnostic research.

    We know that adrenosterone’s role in research and potential preclinical development is rapidly evolving, especially in areas like metabolic pathway targeting, anabolic research, and precision endocrinology. Customers need a supplier that approaches uncertainty with a foundation in facts and a willingness to report setbacks as openly as successes. Some of our most innovative clients have developed entirely new applications after consulting with our synthesis chemists—information exchanged without barriers.

    We share our accumulated knowledge, mistakes and all, because the only goal that really matters is progress for everyone. There’s never a perfect product or process, but approaching each production campaign as a controlled experiment—even after years of experience—ensures we never settle for "good enough." It’s this continuous, feedback-driven cycle that pushes the quality of adrenosterone higher every batch. Every time a customer achieves a breakthrough or resolves a technical hurdle with our materials, it feels like a shared win.

    Conclusion: Why Direct Manufacturing Still Matters

    Some say commoditization and global supply chains will erase the difference between direct manufacturers and resellers. Our record shows the opposite. Only by controlling every link in the process—from raw material selection, to hands-on synthesis, to analytical confirmation and efficient packaging—can suppliers deliver the kind of adrenosterone chemists actually need. Direct experience, verified by results in the field and the trust of long-term partners, differentiates us from companies that measure success by volume rather than outcomes.

    Choose adrenosterone from a manufacturer who stands behind every shipment with the integrity gained from doing the work. See the difference in your results, daily operations, and team confidence—that’s the only way the chemical supply business builds lasting value.