Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Adenosine-5'-Monophosphate Disodium Salt

    • Product Name Adenosine-5'-Monophosphate Disodium Salt
    • Alias AMP
    • Einecs 218-276-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    370190

    Chemical Name Adenosine-5'-Monophosphate Disodium Salt
    Cas Number 4578-31-8
    Molecular Formula C10H12N5Na2O7P
    Molecular Weight 403.18 g/mol
    Appearance White to off-white powder
    Solubility Soluble in water
    Purity Typically ≥98%
    Storage Temperature 2-8°C
    Ph 1 Solution 6.0-8.0
    Synonyms AMP disodium salt, 5'-Adenylic acid disodium salt
    Inchi Key RGIKUYRWUYCOKO-XVFCMESSSA-L
    Ec Number 224-999-2

    As an accredited Adenosine-5'-Monophosphate Disodium Salt factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 5g amber glass vial with a white screw cap, labeled “Adenosine-5'-Monophosphate Disodium Salt” and storage instructions.
    Shipping Adenosine-5'-Monophosphate Disodium Salt is typically shipped at ambient temperature in tightly sealed containers to prevent moisture absorption. The chemical is non-hazardous but should be protected from light and humidity. Ensure packaging meets international transport regulations. Upon receipt, store the product as recommended, usually at 2-8°C or as specified by the manufacturer.
    Storage Adenosine-5'-Monophosphate Disodium Salt should be stored in a tightly sealed container at 2-8°C (refrigerated), protected from light, heat, and moisture. Ensure the storage area is well-ventilated and away from incompatible substances. Avoid repeated freeze-thaw cycles. Proper storage maintains the stability and prevents degradation or contamination of the compound.
    Application of Adenosine-5'-Monophosphate Disodium Salt

    Applications of Adenosine-5'-Monophosphate Disodium Salt in Industrial Manufacturing

    Our expertise as a primary producer of Adenosine-5'-Monophosphate Disodium Salt supports a range of specialized industrial formulations. Below, we present rigorously validated application scenarios for this ingredient, each with practical information on formulation requirements, operations integration, and compliance needs specific to global B2B markets.

    1. Flavor Enhancer in Savory Food Manufacturing

    Major food processors depend on this nucleotide as a flavor potentiator to intensify umami notes in complex savory blends such as soups, sauces, and bouillons. Its capacity to enhance taste with lower sodium formulations drives commercial adoption in international food plants, where it is clearly declared and standardized as an ingredient during blending or post-cook mixing phases. Strict control of addition points and blending parameters ensures compliance and stable taste profiles in mass production environments.

    Industry compliance standards

    • Codex Alimentarius (FAO/WHO) – Food Additive Code INS 640
    • GB 2760-2014 (China Food Additive Standard)
    • EU Regulation (EC) No 1333/2008 on food additives
    • 21 CFR 172.320 (FDA, USA – Food Additives Permitted for Direct Addition)

    Typical usage ratio

    • 0.03% - 0.12% w/w, adjusted for product matrix, sodium contribution limits, and regional labeling requirements.

    Downstream process integration

    • Dry blending with other nucleotides or flavor compounds during spice premix production
    • Post-cooking liquid addition before final product cooling to safeguard nucleotide functionality
    • Slurry incorporation during processed meat brine preparation

    Final product types

    • Instant noodle seasoning packs
    • Ready-to-eat soups and braises
    • Meat analogues and processed meats
    • Fermented savory sauces

    2. Nucleotide Supplement in Infant Formula and Pediatric Nutrition

    Nutritional manufacturers employ this salt as a defined nucleotide source in infant and young children’s dairy formula, where it supports nutritional equivalence to breast milk. Accurate dosing during powder blending or wet-mix processing is essential to ensure precise label claims and achieve health authority approval for infant formula and complementary foods distributed in regulated markets.

    Industry compliance standards

    • GB 10765-2021 (China National Infant Formula Standard)
    • Codex Alimentarius – Standard for Infant Formula and Formulas for Special Medical Purposes (CXS 72-1981)
    • Commission Delegated Regulation (EU) 2016/127 (Infant Formula and Follow-on Formula Regulation)
    • FDA 21 CFR 107.100 (Nutrient specifications, US)

    Typical usage ratio

    • 0.006% - 0.03% by weight of total powder, adjusted to meet cumulative nucleotide content recommended by local authorities; precise levels depend on formula stage and blend with other nucleotides.

    Downstream process integration

    • Dry blending with vitamins and minerals during post-spray-drying phase
    • Wet processing: dissolved in water or oil phase before homogenization
    • QC testing at both pre-blending and final powder stages for homogeneity and specification compliance

    Final product types

    • Infant formula (stages 1, 2, 3)
    • Growing-up milk powders
    • Pediatric dietary supplements (powder or liquid)

    3. Precursor in Pharmaceutical API Synthesis for Adenosine-Based Drugs

    Bulk pharmaceutical synthesis facilities leverage this compound as a building block for the production of purine-based nucleotides and intermediates, especially adenosine and its analogues, integral to injectable medications, research reagents, and diagnostic kits. Chemical reactivity and high purity are critical in this route, as downstream synthetic yields and final compound registration depend on batch traceability from the starting nucleotide salt.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • Ph. Eur. (European Pharmacopoeia Monographs)
    • USP–NF (United States Pharmacopeia & National Formulary)
    • China Pharmacopoeia (2020 edition, ChP)

    Typical usage ratio

    • Entry point determined by stoichiometry for target adenosine derivative synthesis; often used in excess (1.05–1.20 molar equivalents) to maximize conversion yield and control side product formation based on reaction specifics.

    Downstream process integration

    • Dissolved in controlled-pH aqueous solution for nucleoside phosphorylation or transglycosylation reactions
    • Intermediate isolation and purification using preparative chromatography
    • Integrated into GMP-compliant batch records for traceability through to API finalization

    Final product types

    • Injectable adenosine (antiarrhythmic)
    • Cytidine and guanosine analog intermediates
    • Molecular biology reagents for PCR and diagnostics

    4. Biochemical Substrate in Diagnostic Enzyme Assays

    Producers of in vitro diagnostic kits and clinical laboratory reagents apply this salt as a calibrated substrate for enzyme activity determination, including AMP-dependent assays for kinases and phosphatases. Reagent stability, lot-to-lot purity, and low pyrogenicity are critical, since inaccurate baseline readings or contamination directly affect clinical decision support tools and automated analysis equipment worldwide.

    Industry compliance standards

    • ISO 13485:2016 (Medical Devices Quality Management Systems)
    • 21 CFR 820 (FDA QSR for medical devices)
    • CLSI EP25-A (Evaluation of stability of in vitro diagnostic reagents)
    • CE-IVD (Europe, where required)

    Typical usage ratio

    • Reagent formulations: 0.1 mM – 2.5 mM concentrations, tailored for enzyme kinetic range and kit shelf-life validation, with buffer compatibility and interference testing per protocol.

    Downstream process integration

    • Direct integration into liquid or lyophilized reagent kits on automated filling lines
    • QC evaluation for functional purity and substrate background levels prior to reagent batch release
    • Stability testing across intended storage and shipping conditions

    Final product types

    • Enzymatic assay finished kits (AMP kinase, myokinase)
    • Colorimetric and fluorometric microplate assay reagents
    • Clinical chemistry analyzer reagents supplied to hospitals and laboratories
    Free Quote

    Competitive Adenosine-5'-Monophosphate Disodium Salt prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Adenosine-5'-Monophosphate Disodium Salt: Reliable Solution from the Chemical Manufacturer’s Perspective

    Serving the Practical Needs of Researchers and Manufacturers

    In our factory, the process always begins with a basic question: how can we turn complex molecules into real solutions for our customers? Adenosine-5'-Monophosphate Disodium Salt, or AMP-Na2, grew out of this practical mindset. Over the years, this compound has found its way into the hands of pharmaceutical developers, diagnostic kit producers, and laboratories seeking a dependable nucleotide raw material. It’s a cornerstone for folks working on everything from enzymatic reactions to flavor enhancement, but the insights behind its production and application rarely make their way into public conversation.

    Production Integrity Backed by Hard-Earned Experience

    Unlike generic trading houses shopping for stock, we respond daily to the realities of industrial-scale synthesis. At our site, batches pass through controlled environments, monitored every hour to avoid metal contamination and pH drift. Our staff recalls early challenges stabilizing this compound during drying: it hydrates easily, so we had to invest in nitrogen-sealed dryers and stainless-steel vats to hold down the water content.

    Model numbers mean little unless you can trust the contents. Most years, our flagship grade remains the 99%-plus pure Adenosine-5'-Monophosphate Disodium Salt, listed as model #AMP-Na2-99. Beyond purity, we know the biggest difference comes down to moisture and solubility. Any uptick in water content or particulate matter throws off downstream reactions – especially in enzyme studies or injectable-grade applications. We measure residual moisture below 5%, and every drum carries a laser-coded trace number tied back to its original mother liquor.

    Understanding the Core Qualities

    Real-life use always pushes us to consider more than just numbers on a spec sheet. Adenosine-5'-Monophosphate Disodium Salt stands out for its stability under normal warehouse conditions, but it will clump or degrade if stored in humid rooms. Many customers request lots in both fine granular form and a more compact crystalline version. From our years of feedback, the crystalline has longer shelf life and is easy to re-dissolve for batch prep, while the granular works better in automated dispensers.

    Some users enter with a background in classic chemical synthesis, expecting every nucleotide salt to act the same. We learned early that AMP-Na2 did not dissolve as quickly as monopotassium counterparts. That’s predictable based on sodium’s atomic weight and hydration in solution, but it catches folks off guard. Where potassium salts often deliver a quicker burst of solubility, the disodium version holds steady over longer timelines – a tradeoff welcomed by those running controlled time-release reactions or needing reduced ionic strength.

    Ways Clients Put Adenosine-5'-Monophosphate Disodium Salt to Work

    Over time, our clients’ feedback shaped new priorities for production. Life science teams take up the lion’s share, using AMP-Na2 as a substrate in enzyme assays. Diagnostic producers prefer lots with minimal pyrogen and very consistent particle size, telling us this keeps buffers clear and reactions repeatable. On the food additive front, manufacturers blend this salt into seasonings as a flavor enhancer. While it started out mostly for biotech applications, the product’s clean, defined taste means it shows up in low-sodium broths and seasonings.

    We see clear differences between research-use and food-use buyers. Food labs almost always request documentation about allergen control and heavy metal content. The pharma crowd errs on the side of high-purity vials, shipped with tamper-proof liners. Over the past decade, some cosmetic formulation scientists reached out, asking for a low-endotoxin batch. For their sensitive gel and skin-lotion bases, even a few extra micrograms of impurity can cause performance issues. Granular, dust-free batches make it easier for them to weigh out amounts without losing product to airborne scatter.

    Standing Apart from Other Similar Products

    The question comes up: what sets our Adenosine-5'-Monophosphate Disodium Salt apart from other nucleotide salts? At the molecular level, this disodium salt differs substantially from the monopotassium, dipotassium, and monohydrate alternatives. Solubility, taste, and reactivity break along clear lines. For instance, among salt forms, disodium floats to the top for those needing more controlled sodium balances in finished formulas. Monopotassium varieties edge ahead for those targeting low sodium, but the disodium remains a better bet in enzyme-triggered pathways.

    We see it firsthand in side-by-side client trials. Nutritional supplement producers love the sharp, clean taste of disodium. Cosmetic formulators focus on sodium’s role in helping gels maintain clarity and avoid clouding over time. Researchers testing modulations in cellular energy cycles tend to cite the lower ionic interference from disodium versus potassium salts. Those working in beverages, by contrast, sometimes opt for the phosphate-free forms to avoid precipitation in chilled water or acidified solutions.

    Staying Ahead of Supply, Demand, and Stability Issues

    Raw material stability keeps us up at night more than anything else. Over the years, supply chain interruptions for adenosine precursors prompted us to diversify sources and negotiate long-term contracts for core inputs. At one point, quality variations in the ribose feedstock led batches astray. Our team re-calibrated every lot with in-house NMR and HPLC reference curves. Suppliers now pass quarterly audits and must provide full impurity profiles.

    Many factories offer bulk powders at a lower price but miss quality controls on particle size and heavy metal content. We watched many clients switch to us after experiencing inconsistent runs with inferior materials – clumping, off-odors, or unpredictable dissolution rates. No research project can afford those setbacks. This is why we built our plant labs with regular qPCR and LC-MS inspection, ensuring each shipment matches DNA and protein-ligand assay compatibility claims.

    Storage presents a different challenge. Customers sometimes underestimate how temperature swings cause clumping or lead to loss of measured potency. Salt forms — especially disodium — love pulling water from the air, and unlined bags can create hard-caked lumps by the time the drum is opened. We designed packaging with multilayer foil, gas flushing, and desiccant packets. Some call it overkill, but every customer who’s faced a writing-off batch or degraded product understands why we take these steps.

    Why Purity and Documentation Make the Difference

    Few topics matter more for downstream users than reliable documentation and consistent purity. A single out-of-spec batch can set back a research timeline by months. Over the years, we collected dozens of customer stories about the perils of cutting corners: missed deadlines, failed regulatory filings, or contaminated buffers. Our solution? Every production run generates a COA tied back to internal retention samples for ten years. This gives both parties peace of mind and a way to trace any anomaly back to its root.

    Routine checks for lead, arsenic, cadmium, and mercury stay well below global thresholds. Appearance criteria — bright, white crystals with no visible discoloration — follow strict SOP. Customers working in clinical and food environments depend on this, as even slightly off-color batches can raise questions during audits or product launches. Document control isn’t just red tape: it’s our way of standing behind every drum we ship.

    How We’ve Responded to Global Trends and Customer Feedback

    Chemical manufacturing, at its core, means listening to feedback and adapting fast. We see the push toward tighter sodium limits in food and beverage trends. Some buyers now request split-lot blends mixing disodium with monopotassium or magnesium forms. Although this meant extra calibration work, it improved client satisfaction and let us secure multi-year supply contracts. Shift requests like this push us to keep our blending lines agile and our raw material supply diversified.

    Environmental standards kept tightening, especially for non-biodegradable packaging. So we shifted much of our packing stock to recyclable polymers and started offering larger returnable containers to reduce single-use waste. Our waste recovery process now returns most wash water into graywater circuits, cutting discharge by over 60% in three years.

    On the safety front, employee input shaped many SOPs. We reduced manual bag-handling time and updated our airborne particle monitoring in the packaging rooms, lowering the chances of cross-contamination. Training now covers not only spill response but also routine air-changes and glove changeovers — a simple step, but one that protects both batch and operator.

    Addressing User Concerns: Questions We Hear Again and Again

    From the warehouse to the lab, certain questions keep coming up: How does this product differ from competitive imports? Can we guarantee the absence of residual solvents? What assurances exist for batch-to-batch consistency?

    On these points, hard-won experience guides us. Each batch is solvent-free by design: no residual methanol, ethanol, or acetone. Our filtration lineup includes both activated carbon and ultrafine ceramic filters, catching even trace impurities. The only variable between lots is the incoming raw material, and our team commits to rejecting out-of-profile shipments before they ever reach the reactors. This means customers never discover hidden solvent residues or rogue side-products after the fact.

    Batch-to-batch consistency comes down to care at loading, mixing, and filtration stages. We record every adjustment in the batch logs, and post-processing sample vials remain for years. Whether a client orders ten-kilo pails or half-ton totes, every container pulls from the same verified master mother liquor, not leftovers from a previous batch. This practice sets our operation apart from resellers patching together mixed lots or leftovers.

    About imports, our quality teams have compared local batches against major global competitors. Differences often show up in sodium content, pH drift during storage, and trace heavy metals. Customers who ran side-by-side trials describe our AMP-Na2 as supplying steadier solubility profiles and lower color changes over a one-year shelf life.

    The Human Side of Manufacturing: Building Trust Over Time

    Chemical quality is not just about machines and technical controls; it’s built on people trusting the work behind each drum or vial. Our staff put in long hours, double-checking every stage and weighing out each lot by hand, especially when handling fifteen or twenty custom-sized orders in a week. One story sticks out from a few years back: a big food research group called late on a Friday, desperate for last-minute drums after an overseas shipment failed customs. Our techs mobilized, checked, and packed three thousand kilos overnight, shipping them off by daybreak. The customer avoided a production halt, and we learned just how important agility is in this industry.

    We watch the chemical space move fast — campus labs grow into biotech companies, food developers turn to wellness and supplement businesses, and clinical diagnostics become ever more precise. Through all these shifts, Adenosine-5'-Monophosphate Disodium Salt remains a staple because it sits at the intersection of robust chemistry and on-the-ground problem solving.

    Our job as the manufacturer comes down to making sure the product delivered today matches the claims and performance from the first kilogram we ever shipped. Clients return not just for price or convenience, but for trust in a process honed over years of real-world production, error correction, and constant listening.

    Looking to the Future: Meeting New Demands and Technical Challenges

    Regulations change, customer expectations rise, and global supply chains stretch thin. Looking ahead, we continue upgrading our analytical lines – investing in new ICP-MS gear, tightening detection for trace elements, and rolling out real-time online monitoring for bulk reactors. These investments help us spot issues early and free up tech staff for process improvements.

    Sustainability takes a front-row seat now for buyers and regulators alike. Since AMP-Na2 produces a considerable mother liquor volume, our team plans major upgrades to membrane separation and reclaim more phosphate by-products for fertilizer use. Small steps, like moving from gas-fired to electric-driven dryers, also cut our factory’s overall carbon load, a focus both for compliance and reputation with end-users.

    Through all the trends, one fact stays the same: chemical solutions don’t come from shortcuts, they come from steady hands, clear-eyed management, and listening to what customers prove to us through both complaints and compliments. For anyone working with Adenosine-5'-Monophosphate Disodium Salt, feedback and dialogue keep the cycle strong—making the molecule more than the sum of its atoms, but a dependable tool supporting work across dozens of businesses and disciplines.