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HS Code |
809294 |
| Cas Number | 22047-25-2 |
| Molecular Formula | C6H6N2O |
| Molecular Weight | 122.13 g/mol |
| Iupac Name | 1-(pyrazin-2-yl)ethan-1-one |
| Appearance | White to pale yellow crystalline solid |
| Odor | Roasted, nutty, popcorn-like |
| Melting Point | 77-81°C |
| Boiling Point | 255°C (at 760 mmHg) |
| Solubility | Slightly soluble in water, soluble in organic solvents |
| Density | 1.16 g/cm³ |
| Refractive Index | 1.597 |
| Flash Point | 120°C |
| Pubchem Cid | 6395 |
| Smiles | CC(=O)C1=NC=CN=C1 |
| Ec Number | 244-746-4 |
As an accredited Acetylpyrazine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Acetylpyrazine is packaged in a 100g amber glass bottle with a secure screw cap, labeled with hazard warnings and specifications. |
| Shipping | Acetylpyrazine is typically shipped in tightly sealed containers to prevent contamination and moisture absorption. Store and transport at room temperature, away from heat, sparks, and open flames. Ensure compatibility with shipping materials and comply with local regulations for chemical transport. Handle with care and use proper protective equipment during shipping and handling. |
| Storage | Acetylpyrazine should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. Keep the storage area free from moisture and direct sunlight. Ensure proper labeling, and utilize secondary containment to prevent spills or leaks. Follow all relevant safety protocols and local regulations. |
Applications of Acetylpyrazine in Industrial ManufacturingAs a direct producer of Acetylpyrazine, we support multiple industrial sectors with high-purity raw material delivered to precise specifications. Our material enters various regulated production chains where traceability, compliance, and technical accuracy are critical. Below, we outline verified application scenarios, compliance frameworks, dosage protocols, integration stages, and types of downstream finished products. 1. Food Flavor ManufacturingFood flavor houses and ingredient formulators use Acetylpyrazine primarily for its characteristic roasted, nutty, and popcorn-type aroma. It is incorporated into both liquid and powder flavor compositions. Strict regulation controls the identity, purity, and oral dosing levels in final foods, especially in bakery, confectionery, and snack products. Our supply chain transparency supports audit trails from raw material intake through to flavor compound packing. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Tobacco and Vape Liquid FormulationAcetylpyrazine provides creamy, roasted notes in both traditional tobacco blends and nicotine-free vape liquids. Manufacturers use it to create balanced aroma profiles in cigarettes, heated tobacco products, and e-liquids. Compliance focuses on toxicological risk assessment, restricted substance monitoring, and reproducible dosing during fluid or tobacco substrate processing. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Animal Feed Palatant ProductionProducers formulate feed palatants and flavor coatings by incorporating Acetylpyrazine to enhance acceptance in pet foods and animal nutrition. The roasted, brothy note increases palatability, especially for picky eaters. Stringent veterinary and feed additive regulations apply, with batch-wise documentation and contamination controls enforced during multi-ton production runs. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Pharmaceutical Aroma MaskingPharmaceutical manufacturers use Acetylpyrazine in oral dosage products and certain nutritional supplements to mask off-notes from actives or excipients. It serves as a specialty excipient under controlled conditions, undergoing full raw material quality release, stability testing, and toxicological review per local regulations. Traceability and validated use history form part of audit and registration dossiers for finished medicines. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Specialty Chemical SynthesisIn fine chemical synthesis, Acetylpyrazine acts as a key building block for heterocyclic intermediates, especially in the agrochemical and pharmaceutical sectors. Downstream manufacturers specify purity and impurity profile for integration into controlled process steps, with comprehensive analytical documentation required for regulatory submission pathways. Large-scale use is based on route optimization and scalable reaction parameters. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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Acetylpyrazine (2-acetylpyrazine, CAS 22047-25-2) means more to a chemical manufacturer than just creating a flavor ingredient. Our commitment to purity and consistency gets tested with every batch. We operate in an industry where every minor impurity matters, especially for food and vaping flavor standards. Our team works hands-on, refining process parameters, not because it’s trendy, but because we know any shortcut risks the trust earned from those who use our products to create signature tastes.
We make Acetylpyrazine using carefully selected pyrazines and precise acetylation steps. Each reaction stage runs under strict temperature and time settings. The actual work often involves troubleshooting equipment fluctuations or raw material variability, not just reading process manuals. We inspect every drum, every batch, for appearance, odor, and purity by GC. Even with automated controls, our operators and chemists taste and smell samples, trust our senses, and back this with instrument data. It’s a practice built over years of handling food-grade chemicals, in which human perspective complements technology.
Our Acetylpyrazine comes as a crystalline powder, typically off-white. Moisture content stays below 0.3%, as higher levels change the flow during blending for food and vape applications. From our factory floor, we know achieving this moisture threshold requires managing humidity not only in production but also during packaging and transportation. Particle size, rarely appreciated by outsiders, directly affects how easily the powder disperses in flavor bases. We keep particles fine without overdrying, which would make the powder dusty and difficult to handle. Years of feedback from blending rooms have shaped this approach.
Each container carries a typical assay of at least 99%, so downstream processors don’t worry about flavor uniformity batch-to-batch. We do not include anti-caking agents that might interfere with flavor or disclosure requirements. Our operations are built for food and inhalation safety, so we never blend Acetylpyrazine with cutting agents, artificial carriers, or solvents that don’t match global food regulations. What goes in is as pure as our best in-house standards and meets the most demanding flavorists’ expectations.
Acetylpyrazine brings roasted, nutty, bread-like notes that intensify finished flavors. On the ground, most of what we ship travels straight into flavor houses that supply snacks, baked goods, and vaping liquids. Small changes in grade or consistency show up right away when customers formulate new tobacco, chocolate, or coffee blends. We have learned that a minor chemical impurity or a change in crystal structure shifts how the finished flavor performs. Customers call us out if a roasted flavor comes across as burnt or if bread notes sound flat, and we have the factory data to help diagnose what happened.
No synthetic flavor ingredient is as simple as the textbook makes out. Acetylpyrazine might have a low dose threshold, but blending into e-liquid bases or dry snack coatings uncovers challenges beyond the chemistry: statics during powder handling, interactions with other pyrazines, and regulatory limits by region. Our technical support doesn’t only ship the material; we are ready to share practical advice from line experiences—like how to minimize flavor loss during thermal processing or manage the solvent residues that regulators target. Having walked these lines ourselves, our guidance makes a difference to those formulating and processing downstream.
A lot of questions from formulators tackle the subtle differences among the family of pyrazines. Acetylpyrazine stands out due to its unique acetyl group: that simple change amplifies the warm, toasted notes and adds depth not found in ethylpyrazine or methylpyrazines. From the manufacturer’s lens, the difference isn’t academic. The volatility, crystallization, and odor retention mean we fine-tune each process to ensure the right flavor intensity lands in the final product.
Ethylpyrazine for instance, has a sharper nutty scent but lacks staying power in bakery applications. 2,3,5,6-tetramethylpyrazine draws a chocolate-like character but often fades against more robust base notes. We’ve run trials where Acetylpyrazine, even in parts-per-million doses, transforms a bland wheat or nut flavor into something rounded and rich, where substitute pyrazines fall flat or turn metallic. Customers come back year after year because they remember the specific heat and bread crust aroma only true Acetylpyrazine delivers.
Many middlemen and catalog shops market a generic “pyrazine blend,” but these often lack the full aroma profile. Producing Acetylpyrazine in-house, we have control over each reaction and can explain differences in odor, powder flow, and trace impurity profiles to customers who need exacting standards. We don’t believe in shortcuts, and we test all analogues side by side to validate why Acetylpyrazine claims its place in gourmet and technical formulations.
Manufacturing chemicals for food and inhalation brings major oversight—from internal audits to external regulatory inspections. Every kilo of Acetylpyrazine receives a batch number, and we keep data from every step of production. That includes reactor logs, chromatography traces, and even operator notes on unusual smells or temperatures. Our team reviews these records, both to meet legal obligations and to improve processes with every cycle. We strive for transparency not because someone told us to, but because we know that flaws in supply chain traceability cause real damage, both reputationally and to consumer safety.
We hold ourselves to published regulatory specifications, but in practice, internal requirements run tighter. Our chemists run extra headspace GC/MS tests to rule out off-odors. Before we ship, every lot undergoes both technical and sensory panel testing. Many years back, we found that unscrupulous suppliers could dilute product with off-spec pyrazines or non-approved solvents, leading us to double down on quality controls. If a customer identifies even a slight off-note, we invite them to our factory floor, trace back every analytical result, and trigger a root-cause review. Manufacturing at scale doesn’t mean cutting corners; it means building quality into every part of production.
Acetylpyrazine is not a chemical where mistakes are forgiven. We train our operators extensively in handling precautions—from minimizing dust exposure to monitoring air quality. Our filling and packaging rooms run local exhaust ventilation systems, because even small pyrazine releases can leave a pervasive odor and irritate unaware workers. The reality of manufacturing means spill cleanup protocols, personal protective equipment, and exposure monitoring grow from lived experience, not just policy. Our safety culture grew tough after early lessons, and our team holds each other accountable to high workplace standards, because protecting team health always comes before pushing batch volumes.
Every container, whether drum or fiber can, gets sealed and tested to meet moisture and oxygen barrier requirements. On the factory floor, we seek feedback from both the plant team and customers—what clogs in feeders, what powders cake in tubes, what packaging survives temperature swings and humidity in shipment. We learned fast that a high-purity crystalline chemical doesn’t mean much if it clumps during storage or emits odor during transfer. We adjust drying curves based on real shipment data, steadily improving how the material performs once it leaves our factory.
Buyers upstream rarely see the detailed troubleshooting that goes into a batch of Acetylpyrazine. In practice, ending up with yellow or off-white powder instead of near-white signals either an impurity in starting material or mismanaged reaction time. We document every deviation and adjust process controls in real time. Some days, minor pH shifts during synthesis require quick decisions—swap reagents, adjust scrubber capacity, pull samples ahead of schedule. Technicians and chemists meet at shift changes daily to discuss subtle batch differences, reviewing data and sharing observations from the tanks and blending rooms.
On the customer side, issues come through in many forms: clumping in formulation tanks, inconsistent aroma release, trouble redispersing after shipping across climates. We respond by revisiting our process data and sending sample runs for customer-specific needs. Our R&D team works in the same building as production, so feedback flows rapidly and openly. We run duplicate blend trials on both our own lines and customer samples. Many challenges—flavor fade, process instability, excessive carrier residues—require direct conversation, lab testing, and formulation support. Years of direct manufacturing experience give us a realistic perspective: good chemistry and real-world production never stay in perfect alignment, but rapid feedback closes the gap.
Any chemical-maker working with Acetylpyrazine faces pressure to improve environmental outcomes. Our factory invests in solvent recovery systems, closed-loop cooling, and waste handling infrastructure. Beyond permits, our senior team watches energy and waste metrics closely. We rebuilt parts of our distillation column network, not because it looks impressive but because it cuts losses and shrinks our environmental footprint. For every new project or process, the first discussion revolves around effluent, air emissions, and chemical reuse—not only to satisfy inspectors but also because we see the business benefit that follows durable environmental investments.
Even small improvements—reducing shipping weight by reviewing packaging, cutting cleaning frequency through antistatic coating—generate cost and sustainability gains over time. We partner with logistics teams who share our transparency standards and trace the carbon footprint of every shipment, so our customers know their supply chain stays responsible beyond technical performance.
As a manufacturer, trust gets built by showing up in person, answering phone calls late into the night, and never deflecting blame when something goes wrong. Where traders pass off complaints, we log them, investigate root causes, and invite feedback directly into our production meetings. Technical sales here know the production floor, and our process engineers regularly join customer visits, walking through control rooms and packaging bays without stage-management.
We take pride when customers see us not only as a supplier but as a production partner. Flavors and food makers often involve us in troubleshooting their own plant issues—static in weigh hoppers, off-odors during heat cycles, inconsistent batch-to-batch quality. Our team arrives at customer facilities prepared to help inspect, run blind panel tests, and suggest process adjustments based on our firsthand experiences. We build long-term relationships on data transparency, steady product quality, and quick action—we know reputation travels as fast as any flavor molecule.
Food and vaping grade regulations shift rapidly. Years ago, we set out to exceed national and global standards so our Acetylpyrazine would never get rejected at borders or in new product launches. We follow published guidelines by food safety authorities, but our daily practice goes further: every supplier must match our traceability rules, material safety data gets reviewed weekly, and regulatory risk teams sign off on every process change. If a customer identifies a change in threshold levels for pyrazines or asks about unlisted residues, our regulatory team stands ready with documentation and test records.
We collaborate with specialists in labeling, documentation, and import/export compliance to avoid shipment surprises and regulatory fines. Continued education for our team stays essential—we invest in training and knowledge sharing, tracking global shifts in vaping, food flavor, and consumer safety rules. Regular audits help us anticipate and address risks, and lessons from every incident inform future decisions.
New challenges surface yearly: tighter limits on residual solvents, new impurity reporting requirements, and more complex documentation for flavor ingredients used in e-liquids. Our approach relies on early adoption and direct investment in improved analytics. Our customers benefit from this readiness, avoiding disruption as markets change.
Factories that produce Acetylpyrazine do not stand still. Market tastes shift. Regulatory winds blow harder some years than others. Blending methods, flavor formulations, and even finished product delivery all change faster than the textbooks update. We stay ahead through data-driven process control, open communication channels, and an engineering team dedicated to real-world problem solving. Our reputation doesn’t come from a certificate on the wall, but from decades of keeping promises, batch after batch.
We recognize expectations grow higher every year. Flavors companies and e-liquid blenders demand consistent performance and full regulatory compliance. Our mission remains to blend chemical expertise, real production experience, and practical problem solving. Whether shipping to a nearby bakery flavorist or an international vape brand, the same core philosophy powers our work: reliability counts, chemistry is practical, and trust grows every day on the production floor.
Those seeking Acetylpyrazine for high-impact flavor notes will find more than just a product—they find a manufacturing partner ready to support product launches, problem solving, and process improvements shaped by long years on the job. We aim to supply not only the chemical, but the confidence that every batch is made, tested, and shipped with the dedication learned from those who depend on getting it right.