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HS Code |
214243 |
| Cas Number | 132-42-1 |
| Molecular Formula | C14H9NO2 |
| Molecular Weight | 223.23 g/mol |
| Iupac Name | 9-acridinecarboxylic acid |
| Appearance | Yellow to orange solid |
| Melting Point | 324-326°C |
| Solubility In Water | Slightly soluble |
| Density | 1.45 g/cm³ (approximate) |
| Pka | 4.80 |
| Synonyms | Acridine-9-carboxylic acid |
| Smiles | C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)O |
As an accredited 9-Acridinecarboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 9-Acridinecarboxylic Acid, 25g: Sealed in an amber glass bottle with a secure screw cap, labeled with product details and safety information. |
| Shipping | 9-Acridinecarboxylic Acid is shipped in tightly sealed containers, protected from light and moisture. It is handled as a hazardous chemical, following relevant regulations for safe transport. Proper labeling, documentation, and temperature controls are maintained to prevent contamination or degradation during shipping. Personal protective equipment is recommended when handling upon receipt. |
| Storage | 9-Acridinecarboxylic Acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizing agents. Protect it from light and moisture. Store at room temperature, avoiding excessive heat. Ensure proper labeling and keep it out of reach of unauthorized personnel. Always follow relevant safety and regulatory guidelines. |
Applications of 9-Acridinecarboxylic Acid in Industrial Manufacturing9-Acridinecarboxylic Acid serves as a specialty intermediate for high-value manufacturing in sectors requiring advanced heterocyclic chemistry. As the original manufacturer, we support downstream formulators, processors, and OEMs with controlled specifications and technical support across demanding regulated markets. 1. Pharmaceuticals: API Intermediate for Antimalarial AgentsPharmaceutical manufacturers utilize 9-Acridinecarboxylic Acid as a critical intermediate in the synthesis of select acridine-based antimalarial actives. The compound’s carboxylic functionalization directs specific ring substitutions during multi-step batch processes, delivering high chemical yield and narrow impurity profiles. Integration into the synthetic route occurs before final active crystallization, where purity and consistency directly affect regulatory compliance and end-product quality. Industry compliance standards
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2. Dyes & Pigments: Precursor for Acridine Orange SynthesisLarge-volume pigment and dye producers incorporate 9-Acridinecarboxylic Acid into acridine dye syntheses to obtain chromophores with strong fluorescence for textile, biological staining, and analytical indicator applications. The carboxy group ensures regioselectivity during diazotization and coupling, affecting quantum yield and long-term color stability. Processing requires precise pH control and temperature ramp to minimize degradation and off-color formation during pigment isolation. Industry compliance standards
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3. Electronic Materials: Charge Transport Layer AdditiveAdvanced electronics manufacturers in the field of organic semiconductors utilize 9-Acridinecarboxylic Acid as a minor but functionally pivotal additive in charge transport layers for OLED displays and organic photovoltaic devices. The compound’s aromatic structure enhances layer planarity and facilitates electron mobility when copolymerized or co-cast with polymeric binders. Purity and trace metal content receive third-party certification to protect device performance and production yield. Industry compliance standards
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4. Analytical Chemistry: Reference Fluorophore for Instrument CalibrationLabs specializing in analytical equipment calibration deploy 9-Acridinecarboxylic Acid as a reference fluorophore due to its well-characterized excitation and emission spectra. Commercial reference material providers prepare standardized solutions for calibration of fluorometers, HPLC detectors, and spectroscopic instrumentation. Consistent lot analysis and documentation are required to meet third-party ISO-accreditation criteria and to ensure traceability in regulated laboratory environments. Industry compliance standards
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5. Fine Chemicals: Building Block for Custom Ligand SynthesisProducers of specialty ligands for metal-catalyzed reactions and advanced chelation applications employ 9-Acridinecarboxylic Acid for introducing planar, electron-rich moieties into complex molecular architectures. Custom synthesis protocols exploit the acid group for amide coupling or direct esterification. Product documentation includes structural verification, NMR, and heavy metal residual analysis for critical downstream use in catalyst development and fine-chemical production. Industry compliance standards
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Our line of 9-Acridinecarboxylic Acid never strays from the standards we rely on in high-purity organic compound production. This particular derivative has been part of our arsenal for years, consistently demanded by researchers and manufacturers who recognize the need for a crystalline yellow solid that holds up through each step of analysis and synthesis.
From the shop floor to the drying room, this compound’s significance has only grown. Purity reaches 98% or higher, measured from batch to batch using validated analytical methods like HPLC and NMR. General contaminants and side products remain controlled, thanks to well-monitored reaction conditions and temperature profiles. Our staff still double-checks every container leaving the warehouse. Lab analysts log each instrument reading, and paperwork follows each lot through filtration, drying, and final packaging.
9-Acridinecarboxylic Acid belongs to the larger acridine family, but a single carboxyl group at the 9-position gives it unique physical and chemical characteristics. Its molecular structure forms a rigid, fused ring system, offering stability and versatility for further modification. We see this stability pay off in processes that require resistance to common reaction conditions and solvents. Even after years of handling, operators can recognize this material on sight, thanks to its bright yellow hue and a specific melting point.
We tailor bulk production around demand from laboratories and pilot plants working on dye research, organic synthesis, and exploratory pharmacology. Each time teams work with this compound rather than a more generic acridine derivative, they point to the distinct reactivity imparted by the carboxyl position—building blocks that introduce fewer side reactions when handled by experienced chemists.
The material leaves our hands after careful inspection. Depending on customer requirements, we provide 9-Acridinecarboxylic Acid as a free-flowing powder or compressed solid, free of visible dust and extraneous particulates. We keep the particle size within a consistent range—narrow enough to dissolve evenly, coarse enough to prevent loss in air currents or during transfer.
Compared with less pure samples or variations with inconsistent particle size, our approach delivers fewer filtration headaches and less risk of contamination. The process relies on stainless steel contact points and repeated washing that ensures only the desired product lands in the final vial or drum. Teams in our QA lab follow strict protocols to confirm that nothing from the environment or earlier process stages slips through. Acetic acid traces, residual solvents, and inorganic salts stay locked out of the final product.
Research institutions and in-house labs often reach out because 9-Acridinecarboxylic Acid works as a solid starting material for higher-order synthesis. The carboxylic acid group becomes an anchor point in functional group transformations, coupling reactions, and dye intermediates. We’ve supported projects ranging from small-molecule pharmaceutical intermediates to optical brighteners for plastics.
In dye chemistry, acridine derivatives with the carboxylic acid at the 9-position allow for greater variability of hue and solubility modifications. Dye manufacturers turn to this compound to adjust lightfastness and intensity. It lends better control compared to isomeric acids or N-alkylated derivatives. In analytical chemistry, its predictable UV absorption pattern enables calibration of spectroscopic instruments and research screening. These results aren’t speculative—we often provide reference material for academic teams and industrial R&D groups, and they cite repeatable results in public datasets.
Pharmaceutical researchers prefer using our 9-Acridinecarboxylic Acid for its capacity to convert into downstream scaffolds with biological activity. Not every acridine carboxylic acid will deliver the same yield or selectivity in these contexts. We hear about failed reactions using lower-purity product from the open market. High assay and low impurity levels make a visible difference, especially in scale-up operations moving from grams to multiple kilograms.
Plenty of manufacturers put out acridine derivatives, but reproducibility remains a weak link elsewhere. Having kept records over several years, we see that batch-to-batch deviations—if not managed—result in variable melting points and off-spec colors. These may not sound like major setbacks, but an inconsistent material spells trouble for cGMP synthesis, especially when end-users work with tight tolerances on UV absorbance, melting point, and solubility.
Unlike commodity-grade stock that can clog filters or introduce background noise in spectroscopic analysis, our 9-Acridinecarboxylic Acid lands on the bench with high clarity. Analytical certificates back each lot, with results from both internal and third-party labs. We issue complete data sets covering melting point, water content, and identification spectra for each shipment. Teams come to expect less bottle-to-bottle variability, less time recalibrating, and fewer failed syntheses due to questionable raw materials.
Some buyers expect carboxylic acid derivatives to appear the same from any vendor. Years of customer feedback and independent analysis say otherwise. Minor isomeric impurities or oxidized byproducts can change reaction outcome or shelf stability. Knowing that formulators and process engineers work under pressure to cut costs, we avoid the temptation to boost yields at the expense of purity or stability.
Shipping delicate organics presents enough hurdles without introducing unnecessary mysteries into the chain of custody. We rely only on time-tested packing materials—amber glass for smaller units and lined fiber or HDPE drums for industrial quantities. Moisture exclusion and protection from photodegradation remain priorities, so each container carries detailed labeling with storage recommendations. Customers tracking their inventories won’t face surprises months after receipt.
Over the years, we have tracked performance of retained samples under various storage conditions. At room temperature and out of direct light, the material resists degradation over extended periods, with no measurable loss of purity or changes in melting point over a twelve-month span. Direct sunlight or humidity can sap potency, so field users who follow our recommendations achieve the same reliability we see on site.
Plant operators, lab technicians, and research chemists have a low tolerance for unwanted surprises—sudden shifts in color, moisture pickup, or unfamiliar odors. After introducing further filtration steps and environmental controls, we see a marked drop in troubleshooting calls. Most complaints trace back to handling outside our recommended guidelines or cross-contamination stemming from shared scoops and workspaces.
In the acridine family, placement of the carboxylic acid defines behavior in solution, reactivity in derivatization, and final performance of downstream products. Ask a synthetic chemist to swap in the 1- or 2-carboxylic acid analog, and reactions often grind to a halt or require heavy re-optimization. We’ve watched project leads waste weeks correcting lineups in multi-step syntheses after initial snags trace back to the wrong isomer or mixed supplies.
9-Acridinecarboxylic Acid’s structure allows access to specific coupling chemistry and ligand designs needed for dyes, fluorescent markers, and advanced drug analogs. Compared to N-alkylated or halogenated substrates, the plain carboxylic acid provides more options for further functionalization—making the difference in cost or feasibility for projects at scale. Its solution properties also ease purification, so our buyers spend less time in column chromatography or expensive re-crystallization.
While other acridine derivatives find application as DNA intercalators or anti-microbial agents, specific projects can only succeed by starting with the 9-carboxyl isomer. Some of our clients, particularly in life sciences, require strict documentation confirming isomeric purity. Our internal data and longstanding relationships with university labs reinforce the need for such precise verification—cutting back on regulatory headaches during final product registration and approval.
Working with aromatic carboxylic acids demands respect for standard lab safety. Despite the compound’s stability, dust should always be kept at bay, and proper ventilation ensures that accidental inhalation never becomes an issue. Our operators go through regular training in the handling and disposal of organic acids, keeping exposures to a minimum and following waste codes for aromatic organics.
In the manufacturing environment, spills remain rare because containers close tightly at every step. We run periodic drills for our operators, focusing on neutralizing and collecting waste, using absorbents designed for aromatic compounds. Downstream users benefit from our guidance on solvent use, waste-neutralization procedures, and best practices for record-keeping. Nothing leaves our site without dual checks from environmental and safety officers.
Feedback from downstream processors prompted us to supply more detailed guidance in our shipping documents. For example, consistent pH monitoring during disposal, along with solvent compatibility advice, has enabled waste managers to keep events non-reportable across multiple jurisdictions.
Our plant team doesn’t operate in isolation. Technical sales and lab support teams relay insights from R&D partners who need small tweaks in product grade, handling, or documentation. Sometimes this means tailoring drying protocols to suit a specific downstream synthetic method, or sourcing alternative solvents for washing to remove a rare impurity detected by x-ray fluorescence or mass spectrometry.
In recent years, open communication led to a new grade of 9-Acridinecarboxylic Acid designed for trace metal-sensitive photophysical testing. We worked side by side with instrument manufacturers and academic labs to cut trace iron and copper content below industry recommendations. Adjusting purification workflows involved investment in new apparatus; our team saw it as a challenge and a chance to stay ahead of regulatory and technical shifts. As a direct manufacturer, we enjoy the give-and-take with those pushing boundaries in their own fields.
Sourcing raw materials for specialty chemicals presents recurring challenges. Our supply-chain staff sources from vetted partners and audits solvent and base stocks annually. Market swings and transport delays always add uncertainty, but we maintain buffer stocks and engage in direct forecasting with priority buyers who count on just-in-time delivery. We adjust production schedules to align with the seasonal and fiscal cycles unique to industries as different as university research and mass-market dye production.
Market data suggests a rise in specialty dye demand and a renewed interest in acridines for pharmaceutical development. Teams in both spaces push us on specs, traceability, and documentation. Our records, archival samples, and ability to pivot between batch and continuous-process production keep our customers ready for audits. The combination of synthetic know-how and direct feedback pushes us to not just match, but exceed, requirements in critical areas identified by new standards and evolving application needs.
Feedback drives us. Every warning about waste or shelf life, every unique application in dyes or biologically active agents, teaches us what really matters. Our 9-Acridinecarboxylic Acid stands out not through price alone, but from hard evidence—batch after batch, bottles delivered on time, and problems solved before end users face them. We see new grad students and veteran lab managers both remark on the difference a consistent supply makes for their work.
We don’t rely on buzzwords or rote guarantees—just the commitment molded by years of learning the quirks of each molecule. The right carboxylic acid placement, steady purity, and uncompromising process control earned our 9-Acridinecarboxylic Acid its role on the bench. Each barrel, drum, or bottle we fill reflects the knowledge earned on noisy production floors, at dusty QC stations, and in conversations with researchers around the world. The work never finishes, but with a product this reliable, more teams push their projects forward and know exactly what they can expect from every order.