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8-Bromooctanoic Acid

    • Product Name 8-Bromooctanoic Acid
    • Alias 8-Bromooctanoic acid
    • Einecs 223-120-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    826497

    Product Name 8-Bromooctanoic Acid
    Cas Number 2085-92-7
    Molecular Formula C8H15BrO2
    Molecular Weight 223.11 g/mol
    Appearance White to off-white crystalline solid
    Melting Point 31-34°C
    Density 1.39 g/cm³
    Solubility In Water Slightly soluble
    Purity Typically ≥ 97%
    Synonyms 8-Bromooctanoic acid; Octanoic acid, 8-bromo-
    Storage Conditions Store at 2-8°C, tightly closed, protected from light
    Smiles C(CCCCCBr)CC(=O)O
    Inchi InChI=1S/C8H15BrO2/c9-7-5-3-1-2-4-6-8(10)11/h1-7H2,(H,10,11)

    As an accredited 8-Bromooctanoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 8-Bromooctanoic Acid, 25g, supplied in a sealed amber glass bottle with chemical-resistant screw cap and tamper-evident seal.
    Shipping 8-Bromooctanoic acid is shipped in tightly sealed, chemical-resistant containers under controlled conditions to prevent leaks and contamination. It should be transported as a hazardous material, protected from moisture, heat, and incompatible substances, and in compliance with regulatory guidelines for corrosive and reactive organic acids. Proper labeling and documentation are required.
    Storage 8-Bromooctanoic acid should be stored in a tightly sealed container in a cool, dry, and well-ventilated area. Keep it away from sources of ignition, direct sunlight, and incompatible substances such as strong bases or oxidizing agents. Store at room temperature or as specified by the supplier, and label the container clearly. Avoid exposure to moisture to prevent degradation.
    Application of 8-Bromooctanoic Acid

    Applications of 8-Bromooctanoic Acid in Industrial Manufacturing

    8-Bromooctanoic Acid functions as an essential specialty intermediate within several high-value chemical streams. Our manufacturing expertise supports consistent, specification-compliant supply for direct use in regulated downstream sectors. Below, we detail verified industrial application scenarios, highlighting their specific quality and process requirements.

    1. Pharmaceutical Synthesis: API Intermediate Production

    Our material is frequently incorporated into the multi-step synthesis of certain active pharmaceutical ingredients, serving as a selective alkylating agent in the preparation of β-substituted carboxylic acids. Production teams in regulated pharma plants introduce it during early stage synthesis or in late-stage functionalization to generate key molecular frameworks, with close monitoring of purity and by-product profiles as required under cGMP environments. Typical batch process integration relies on robust analytical controls to confirm identity and residual impurity levels before moving intermediates to subsequent reactions.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF, Ph.Eur. monographs (where applicable for final APIs)
    • 21 CFR Part 210/211 for finished drugs
    • EU GMP EudraLex Volume 4

    Typical usage ratio

    • 1.2–1.6 molar equivalents relative to nucleophilic reactant, with adjustment based on desired conversion and impurity control; weight percentage in reaction mixture typically ranges from 10% to 18% of total input mass.

    Downstream process integration

    • Introduced during the alkylation or substitution stage in multi-step reaction trains; contained in vessels with in-process QC checkpoints for monitoring reaction progress and selectivity.

    Final product types

    • API intermediates for β-blockers, anticonvulsants, and select antiviral compounds; delivered as purified solids or solutions for subsequent production stages.

    2. Agrochemical Intermediate Manufacturing

    8-Bromooctanoic Acid sees application in the targeted synthesis of advanced agrochemical intermediates, providing a long-chain functional group for the construction of novel herbicides and selective insect control agents. Downstream plants often use it to build molecular backbones that require halogenated fatty acid units, with environmental and safety oversight according to agrochemical regulations. This step typically follows stringent effluent management due to halogen waste considerations and aligns with acceptable impurity limits in the final technical material.

    Industry compliance standards

    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • OECD Guidelines for the Testing of Chemicals
    • REACH (EC) No 1907/2006 registration for intermediates within the EU
    • ISO 9001 certified process controls for quality documentation

    Typical usage ratio

    • 0.8–1.3 molar equivalents per substrate, with specific levels (8–12% by weight) set according to target molecule design and desired substitution pattern; process optimization driven by residual bromide testing in product QC.

    Downstream process integration

    • Charged during the functional group installation stage after initial scaffold assembly, often in halide-exchange or coupling reactions on automated or semi-batch lines with closed waste handling systems.

    Final product types

    • Precursor esters and acids for use in herbicide, acaricide, and miticide formulation; output as crude or partially purified chemicals to be further elaborated or formulated for field use.

    3. Surface-Active Agent & Surfactant Intermediate

    Selective customers in the specialty surfactant sector integrate 8-Bromooctanoic Acid as a chain-length modifying agent in the production of custom amphiphilic molecules. Formulators use the material within esterification or amidation protocols to construct specialty surfactants with tailored solubility or emulsification performance for industrial cleaning and personal care formulations. QC samples are routinely screened for bromine content to comply with regulatory thresholds and to control downstream product consistency.

    Industry compliance standards

    • ISO 9001:2015 for documented SOPs
    • EU Detergents Regulation EC/648/2004 for allowable components in cleaning products
    • REACH registered uses for surfactant intermediates
    • FDA 21 CFR 178.3400 (when used as indirect food-contact surfactants)

    Typical usage ratio

    • 5–15% by weight of the batch, determined by molecular design and target HLB (hydrophilic-lipophilic balance); formulation engineers select input ratio based on chain length and required functionalization yield.

    Downstream process integration

    • Added into the alkylation or esterification reaction vessel after core fatty acid or alcohol selection, followed by removal of residual bromide through washing or distillation prior to product finishing.

    Final product types

    • Intermediate surfactants for industrial emulsifiers, dispersing agents, anti-static additives; supplied as concentrated bases or in blend-ready liquid form.

    4. Specialty Polymer Monomer Synthesis

    Polymer chemists utilize this raw material to introduce brominated or carboxy-terminated sites in tailor-made monomers for advanced polymer architectures, especially for high-performance coatings or block copolymer production. The acid is reacted via controlled substitution to achieve defined end-group functionalities, contributing to cross-linking performance and polymer-compatibility in demanding end-use environments. Systems maintain traceability from raw input to final resin quality, referencing application-specific monomer purity and residual halide thresholds.

    Industry compliance standards

    • ISO 14001 for environmentally controlled processes in polymer manufacturing
    • REACH registration for monomer safety data
    • ASTM D256 for physical property assessment on polymers
    • Customer-specific monomer purity specification sheets

    Typical usage ratio

    • 3–10 mol% relative to total monomer feedstock, with process engineers adjusting input levels by target molecular weight and cross-link density; equivalent weight basis for batch records ranges from 6% to 20% of monomer mix.

    Downstream process integration

    • Integrated into prepolymer synthesis by addition after core backbone formation; radical or ionic initiators drive polymerization, following real-time monitoring for functional group incorporation and conversion.

    Final product types

    • Brominated or carboxy-terminated prepolymers for UV-cure coatings, specialty elastomers, adhesion promoters, or impact-modifier masterbatches; output in liquid resin or pelletized solid formats.

    5. Industrial Biocide Precursors

    Within the specialty chemical sector, formulators rely on this material to synthesize alkyl bromide-containing biocide building blocks. Manufacturing focuses on constructing molecular scaffolds that leverage the reactivity of the bromo acid for further derivatization, ensuring regulatory-compliant handling of residual halide and bromate by-products. Formulation batches follow traceability protocols to meet audit requirements for antimicrobial manufacturing environments.

    Industry compliance standards

    • BPR (EU Biocidal Products Regulation) (EU) No 528/2012
    • US EPA FIFRA (Federal Insecticide, Fungicide, and Rodenticide Act)
    • ISO 13485 for quality management where used in medical-related antimicrobials
    • Customer-specific technical grade specification sheets

    Typical usage ratio

    • 5–12% by weight within reaction mixtures for target intermediate formation; final input ratio determined by molecular scaffold construction and targeted release profile of the end-use biocidal actives.

    Downstream process integration

    • Fed during the alkylation, acylation, or cyclization stage to produce haloalkylated intermediates; operations employ contained systems for handling and monitor halide discharge according to regulatory limits.

    Final product types

    • Precursors for non-oxidizing biocidal additives in industrial water treatment, oilfield chemicals, closed-loop disinfectant systems; shipped as technical concentrates or isolated solids for on-site formulation.
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    Certification & Compliance
    More Introduction

    8-Bromooctanoic Acid: A Closer Look at Production, Application, and Quality

    What Sets Our 8-Bromooctanoic Acid Apart

    We produce 8-Bromooctanoic Acid at our plant from scratch, starting each batch with raw linear alkanes processed through halogenation and oxidation under controlled temperature and pressure. Our site team knows the difference that exact preparation steps make in both purity and reactivity, especially in this family of bromo acids. Customers notice it, too, if even a fraction of excess alkane or bromine stays behind and throws off yields downstream. The model for our 8-Bromooctanoic Acid reflects years of scaling up lab protocols, ensuring the right bromine placement every time. Specification matters: Our standard batch holds a purity of at least 98 percent by GC, moisture at less than 0.5 percent, and color remains close to water-white—observations you see reflected in assay certificates, not just sales pitches.

    Consistent Results Come from Hands-On Control

    Down the production line, we don’t rely on bulk blending post-reaction. Instead, each batch gets careful cooling and filtration, then vacuum drying to pull out even the stubborn traces of byproduct. Our technicians track endpoint detection, meaning fewer surprises with residual bromide or trace solvents left in cargo tanks. This matters because 8-Bromooctanoic Acid creates consistent intermediates only when handled this way; one sticky spot in the purifying glassware can lead to contamination in the product drum and headaches in downstream synthesis.

    What Goes Into Every Order

    As chemical manufacturers, real-time feedback from our reactors tells us every lot is distinct, even with fixed recipes and automation. We adjust batch-by-batch for factors like feedstock chain length, bromine addition rate, and the time acid is exposed for oxidation. In our experience, quality measures start before drums ship—every sample undergoes GC and NMR checks before being bottled for shipment. Stories circulate of someone buying material marked as “pure” from brokers only to get off-spec batches that throw off analytical results and conversion rates.

    What we send always aligns with what our analytical chemists see in pre-shipment data. Shipments roll out with full lab records. Practically, this means chemists in pharma, agro, and academic labs spend more time on actual research, and less rerunning crude reactions to chase down impurities.

    Key Uses Shaped by the Chemistry

    8-Bromooctanoic Acid opens the door to several organic transformations and specialty syntheses. It’s a favored reagent for producing straight-chain brominated fatty acids, which serve as starting points for surfactant development and new drug candidates. In esterification, alkylation, and amidation reactions, the eight-carbon skeleton with bromine at the terminal position gives both reactivity and flexibility for building larger molecules.

    We see our 8-Bromooctanoic Acid move most into pharmaceutical synthesis, especially for constructing bioactive lipids and as an intermediate for functionalized amines. Teams on the bench use this acid to build PEG-conjugates, explore CNS-active molecules, or add hydrophobic chains into experimental polymers. In materials science, these C8-bromo acids lay the foundation for hydrophobic surface modifications on glass and metal, improving anti-fouling properties under real-world conditions.

    Choosing the correct starting acid proves crucial—switching chain length or moving the bromine away from the terminal carbon alters both reactivity and downstream structure. 8-Bromooctanoic Acid consistently delivers the right length and halogen position for most pharmaceutical intermediates and fine chemical R&D projects in our experience. The eight-carbon backbone pairs well with both traditional peptide and small-molecule synthesis routes, letting customers generate a wide variety of esters, amides, and other derivatives without unexpected side reactions.

    Differences That Shape Purchase Decisions

    8-Bromooctanoic Acid comes from a family of similar chain-length acids, usually between six and ten carbons, some with halogen substitution at internal or terminal positions. We field requests from customers occasionally asking about 6- or 10-Bromooctanoic Acids, or even variants with chlorine swapped in place of bromine. Time and again, end-users find odd-chain or internal-bromo acids less compatible with target reactions, often because their melting points, solubilities, and coupling tendencies change just enough to affect process reproducibility.

    Terminal bromination and a straight octanoic backbone set this compound apart. Some production routes in the market still leave behind residual dibrominated side products or isomer blends. Our process cuts those impurities to trace levels, confirmed by both in-house and customer-run analytical work. Over time, our buyers save both on yield and in troubleshooting hours lost to off-flavors in intermediates, poor conversions, or the kind of lingering unknowns that pop up in NMR spectra when product isn’t pure.

    Transparency in Production and Testing

    From years on the production floor, we’ve learned that tracking each batch close to its source makes the biggest difference in safety and reliability. Plant-level transparency means logging each increment of bromine, recording every filtration time, and maintaining clear records of both in-process and final product analytics. We don’t cut corners, because minor shortcuts in drying or separation show up months later as customer complaints about discoloration, excessive odour, or, worse, unexplained toxicity results in downstream experiments.

    We regularly perform impurity profiling—targeting both residual reactants and trace side products. Our batches are GC-MS mapped against both the standard and our own archive of historical runs. If outliers crop up, we stop the line, taking corrective action. We see far too often that downstream issues arise from sources that could have been controlled with careful in-house screening, not fixed outside after the fact.

    Shipping Considerations: Keeping the Acid in Optimal Condition

    Brominated acids react more easily to heat and light than plain octanoic acids. Over several years, we’ve adjusted our storage and shipping protocols to guard against yellowing, degradation, and caking. Our drums use food-grade epoxy lining whenever possible. Bulk loads move in insulated tankers during the warm months to keep product at stable temperatures. These precautions grew out of real feedback: a hot container sitting in summer sun can arrive as a discolored, partly decomposed sludge, complicating downstream use and sometimes invalidating days of customer prep work.

    Packing lines follow strict schedules, and every container gets double-seal checked for leakage and cross-contamination. Each closure carries a serialized tag, and batch tracking persists through arrival at the client site. Shipments move quickly, bypassing third-party storage to minimize handling, which keeps what we send as close to the original assay as possible by the time it reaches the lab floor.

    Sustainability and Waste Management

    Making bromo acids generates halogen-containing byproducts requiring careful handling. Through experience, we’ve learned raw material selection and efficient reactor design slash the halide load, cutting production waste and improving work-up safety for our teams. We reclaim unreacted bromine and recycle process water after careful neutralization and monitoring. This level of oversight comes from practical necessity: regional discharge rules and real risk of regulatory audit mean every drum counts, and missed control points mean both environmental harm and lost trust with our customers.

    Over time, we scaled up closed-cycle scrubbing units and heat exchangers at our main site, both for operator health and for energy recovery. Teams track daily effluent and make chemical adjustments as needed. Buyers from large pharma, fine chemicals, and academic sectors increasingly ask for evidence of responsible practices, not just a spec sheet. Out of both pride and practicality, we share our internal tracing logs and environmental reports upon request.

    Safety and Handling Knowledge from the Source

    It’s not just a matter of putting bromo acid in a drum and shipping it out. 8-Bromooctanoic Acid needs handling protocols that blend safety with day-to-day realities of a busy lab. We train our own operators using actual case studies of contamination and reactions gone awry. That same knowledge shapes our technical support for customers—covering splash prevention, fume mitigation, and correct neutralization steps. Our technical service gets firsthand calls about acid etching, skin contact, or improper dilution, and we walk teams through the right solutions instead of reading stock answers off a sheet.

    Experience teaches that the most common injuries remain preventable by sticking to standard PPE, good ventilation, and lockout during transfer. We keep material in vented storage for even short-term warehousing, and maintain clear labeling on every drum for both GHS and region-specific classification standards. Customer feedback on safety leads to continual refinements in package design, including improved ergonomic closures for lab-scale bottles that reduce slip risks and cross-contamination.

    Comparison with Other Brominated Acids and Sourcing Issues

    A range of bromo derivatives exists on the market, but end-users in R&D often overlook subtle differences in bromine position, chain length, and base purity. Through direct conversations with synthetic chemists using our 8-Bromooctanoic Acid, we hear recurring stories about failed reactions traced back to “lookalike” materials with slightly off specifications. We test competitor samples side-by-side in equivalent reactions to assess conversion rates, impurity profiles, and isolated yields. These bench-level comparisons often show small but critical deviations—sometimes a percent or two in starting acid purity, sometimes a color mismatch that indicates the presence of oxidative byproducts.

    Reliability over multiple years of purchase means more to most labs than chasing the lowest price. Tales of lost projects or repeating scaleups because of inconsistent feedstock repeat enough times that focus stays on building long-term relationships with manufacturers who demonstrate traceability and direct batch control. Distribution channels may promise speed or price savings, but experience makes it clear that sourcing directly from manufacturers with hands-on QC saves both time and cost in actual workflow.

    Expectations Around Regulation and Compliance

    Making 8-Bromooctanoic Acid involves regulation at every step, from local fire codes to international transport controls over halogenated acids. We keep up with evolving standards by staying active in trade groups and engaging early with regulatory agencies, aiming to anticipate rule changes before they become roadblocks. This makes sure typical roadblocks, like delayed shipments or border holds due to incomplete documentation, don’t become a regular feature for our customers.

    Detailed certificates document not only purity and composition but test for restricted contaminants such as persistent organic pollutants, heavy metals, and volatile residue. Our compliance officers track new requirements each year, adjusting internal protocols so new and returning customers both receive material that meets their own governing standards. This approach stems from direct experience—not simply producing for specification, but proactively tracking how those specs shift over time, and translating that into everyday shipping practice.

    Collaborative Development with End Users

    Production doesn’t end at the plant gate. In the past year alone, we’ve supported custom modifications—longer carbon chains, mixed halides, or controlled isotopic enrichment—to help R&D teams push their projects forward. Many breakthroughs in complex molecule synthesis stem from minor tweaking of available building blocks. By working with development partners early in their timeline, we help spot bottlenecks at the material level before they become problems at scaleup.

    This ongoing technical exchange leads to refinement of both purity targets and packaging solutions, based on direct customer input. We test new stabilizers and drum liners at customer request, and collect returned feedback from chemists working in varied fields—pharmaceuticals, electronics, surface science. More than once, industry partners stemming from this back-and-forth have reported reductions in both development time and failed experiments, thanks to small adjustments in starting acid quality or consistency.

    Field Knowledge in a Rapidly Changing Market

    Every year, new applications for 8-Bromooctanoic Acid emerge, many driven by advances in drug discovery or surface modification. Synthetic organic chemistry moves quickly, and so does our process team—refining the manufacturing process to reduce side products, improve overall safety, or shorten lead times. Field data and academic research help guide our plant modifications, as does direct feedback from customer teams running pilot studies or moving promising molecules toward the market.

    Our position as a hands-on chemical manufacturer creates a feedback loop: each data point from a customer, each returned batch, each suggested improvement feeds into the next round of process revisions and product development. Over time, this approach has increased both our own reliability and the diversity of fields using our product.

    Summary of What We Stand For

    Year after year, our commitment to in-house production, full batch control, and constant feedback with end-users shapes both the 8-Bromooctanoic Acid we deliver and the relationships built around it. Whether material goes to an academic researcher, a pharmaceutical intermediate synthesis, or a specialty polymer project, the difference comes from attention to process and transparency. That’s how we guarantee each drum, bottle, or tanker aligns with what our customers need, born from direct experience and refined by continual dialogue across the chemical community.