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8-Bromo-1-Octene

    • Product Name 8-Bromo-1-Octene
    • Alias 1-Bromo-8-octene
    • Einecs 211-247-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    659016

    Cas Number 1631-83-4
    Molecular Formula C8H15Br
    Molar Mass 191.11 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 189-191 °C
    Density 1.11 g/cm³ at 25°C
    Refractive Index 1.454-1.456
    Flash Point 61 °C (closed cup)
    Solubility In Water Insoluble
    Synonyms 1-Octene, 8-bromo-; 8-Bromooct-1-ene
    Smiles C=CCCCCCCB
    Pubchem Cid 17859

    As an accredited 8-Bromo-1-Octene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

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    Application of 8-Bromo-1-Octene

    Applications of 8-Bromo-1-Octene in Industrial Manufacturing

    Our 8-Bromo-1-Octene serves as a precise functional intermediate for multiple high-purity synthesis processes across demanding industrial sectors. As a direct manufacturer, we ensure strict adherence to industrial standards from reactor charging to packaging, answering downstream needs for reproducible quality and traceability. Below, we present detailed application insights by each major downstream sector.

    1. Fine Chemical Intermediate for Pharmaceutical Synthesis

    Pharmaceutical manufacturers use 8-Bromo-1-Octene as a key alkylating agent during the development of advanced APIs, including the coupling steps for heterocyclic and aliphatic scaffolds. For certain therapeutic candidates, it enables direct carbon chain elongation or functional group introduction, supporting development under strict impurity control and batch reproducibility. The raw material integrates into multistep synthesis where low halogen residue and high lot consistency must match ICH requirements. End users validate our grade through in-process chromatographic testing prior to downstream condensation or cyclization procedures preparing intermediates for cardiovascular, antiviral, and central nervous system drugs.

    Industry compliance standards

    • ICH Q7 GMP guidelines for API manufacture
    • US FDA 21 CFR Part 211 (finished pharmaceutical products)
    • EU GMP Directive 2003/94/EC
    • ISO 9001:2015 certified manufacturing for traceability

    Typical usage ratio

    • Added at 1.1–1.2 mole equivalent to target nucleophile — subject to impurity control and yield optimization
    • Adjust final loading based on route selectivity and downstream purification capacity

    Downstream process integration

    • Charged during early-stage alkylation or bromoalkene substitution steps
    • Carefully monitored via HPLC and GC for conversion and residual bromide
    • Combined with metal catalysts or bases as reaction partners in closed-system reactors
    • Subject to in-process quality checkpoints before dehydration or secondary modification

    Final product types

    • Key pharmaceutical intermediates for small-molecule APIs
    • Building blocks for specialty cytostatics and antivirals
    • Precursors for prodrug functionalization platforms
    • Advanced agrochemical intermediates with related chemotypes

    2. Co-monomer in Polyolefin and Specialty Polymer Manufacture

    Major polymer plants deploy 8-Bromo-1-Octene as a specialty co-monomer to introduce pendant or terminal bromide groups into high-performance polyolefins, oxygen barrier layers, and functionalized polymer blends. Controlled dosing in solution or gas-phase polymerization using Ziegler-Natta or metallocene catalysts delivers functionalized chains suited for adhesive, packaging, and wire insulation industries. Our production minimizes peroxide and trace halide contamination to meet high polymer-grade specifications. Automated feed and inert transfer equipment prevent side reactions that would otherwise reduce molecular uniformity or raise off-spec material rates.

    Industry compliance standards

    • ASTM D4635-14 for polyolefin-based plastics
    • ISO 9001:2015 certified QMS for polymer raw materials
    • FDA 21 CFR 177.1520 for polymers in food contact (where applicable)
    • REACH compliance (EC 1907/2006) for polymeric substances

    Typical usage ratio

    • Introduced at 0.5–3.0% by weight relative to ethylene or propylene monomer mix
    • Ratio adjusted according to glass transition or molecular functionality target

    Downstream process integration

    • Metered into continuous polymerization reactors as a functional group donor
    • Incorporated with comonomers under inert atmosphere with in-line bromide monitoring
    • Product chain transfer agent potential; downstream dehydrohalogenation possible for advanced copolymers
    • Finished polymer tested for melt flow and residual bromide before extrusion or molding

    Final product types

    • High-impact thermoplastic olefin copolymers (TPOs)
    • Functionalized barrier films for technical packaging
    • Wire and cable insulation compounds
    • Adhesive polymer blends for industrial assemblies

    3. Intermediate in Surfactant and Specialty Chemical Synthesis

    Producers of advanced surfactants and specialty chemicals select 8-Bromo-1-Octene as an intermediate for the manufacture of alkylated quaternary ammonium compounds, betaines, and cationic emulsifiers. Its terminal bromoalkene structure allows for selective nucleophilic substitution by amines or alcohols to generate a wide set of surface-active agents with tailored hydrophobic-lipophilic balance. We ensure narrow isomer content and low residual water, facilitating purification and downstream conversions. The supplied material performs under both batch and semi-continuous synthetic setups at surfactant plants, especially where downstream chain modification or etherification occurs.

    Industry compliance standards

    • EU Regulation (EC) No 648/2004 on detergents
    • ISO 9001:2015 certified quality documentation
    • EN 12764:2004 for surfactant safety in cosmetics/cleaners
    • National registries for chemical ingredients (eg, TSCA, IECSC)

    Typical usage ratio

    • Applied at 1.0–1.3 mole equivalent toward nucleophile (amine/alcohol)
    • Formulation flexibility based on required alkyl chain density and reactivity profile

    Downstream process integration

    • Dosed into nucleophilic substitution or condensation step with stirring and temperature control
    • Monitored for conversion and free bromide with titration/GC
    • Feed adjusted based on final surfactant performance parameters
    • Product passed through liquid-liquid extraction and vacuum stripping as required

    Final product types

    • Textile and leather wetting agents
    • Cationic fabric softener actives
    • Cosmetic emulsifiers and conditioners
    • Specialty oilfield and agrochemical surfactant blends

    4. Synthesis Reagent in Advanced Organic Electronics Materials

    Leading electronic chemical producers utilize 8-Bromo-1-Octene for the insertion of functional alkyl chains during the crafting of specialty materials for OLEDs, organic photovoltaic cells, and advanced photoresists. It participates in the modification of rigid chromophores or conjugated backbones via cross-coupling and addition chemistry, imparting solubility and electronic properties essential for film uniformity and device longevity. Our high-assay grade, controlled for trace metals and water, supports highly sensitive downstream purification, such as column chromatography under anhydrous conditions. Strong quality documentation supports audits for critical supply chains serving electronics OEMs.

    Industry compliance standards

    • IPC-4101 for base electrical and electronic laminate materials
    • ISO 9001:2015 for supply chain documentation
    • Restriction of Hazardous Substances (RoHS, EU 2011/65/EU)
    • Reporting requirements under TSCA (USA) for novel materials

    Typical usage ratio

    • Typically charged at 1.05–1.2 mole equivalent per aromatic or conjugated system
    • Ratio set by solubility and photoactive layer performance targets

    Downstream process integration

    • Engaged in metal-catalyzed cross-coupling (e.g., Suzuki, Stille, or Heck reactions)
    • Added under nitrogen in jacketed reactors at specific temperature profiles
    • Crude product typically refined by column chromatography or recrystallization with impurity monitoring
    • Post-processing under cleanroom or high-purity conditions as required for device qualification

    Final product types

    • OLED emitter and host molecules
    • Electron/hole transport polymers
    • Photoresist components for semiconductor manufacturing
    • Polymerizable materials for organic photovoltaics (OPV) and OFETs

    5. Building Block for Agrochemical Active Ingredient Synthesis

    Pioneering agrochemical producers implement 8-Bromo-1-Octene as a foundation for selective alkyl chain introduction during the manufacture of novel insecticides, fungicides, and herbicide analogs. Its bromo-terminated structure allows tailored chain extension, controlling hydrophobicity and bioactivity profile in final actives or synergists. Our batches undergo stringent QC for residual solvents and low-level halide content, meeting requirements for environmental and product registration dossiers. Production volumes are scalable to serve both pilot and full bulk API stages, with traceability supporting risk assessment for field use approval.

    Industry compliance standards

    • FAO/WHO Specifications (JMPS) for pesticide technical materials
    • OECD Guidelines for the Testing of Chemicals (analytical methods, purity)
    • ISO 17025 lab documentation for registration support
    • REACH/CLP for substance reporting and transport

    Typical usage ratio

    • Typically used at 1.0–1.3 mole equivalent based on alkylation or cyclization yield assessment
    • Final dosage tailored following bioactivity and field performance studies

    Downstream process integration

    • Supplied to batch reactors for coupling or ring closure in core molecule synthesis
    • Coreactant in nucleophilic substitution or controlled hydrolysis pathways
    • Monitored for complete conversion, with stepwise purification and impurity profiling
    • Active intermediates typically formulated post-reaction before encapsulation

    Final product types

    • Novel pyrethroid insecticides and analogs
    • Long-chain substituted herbicidal precursors
    • Organic fungicide intermediates
    • Seed treatment active ingredient scaffolds
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    Certification & Compliance
    More Introduction

    Exploring 8-Bromo-1-Octene: A Versatile Building Block for Modern Synthesis

    Chemistry shapes much of what we touch, wear, and use daily, even though its building blocks often go unnoticed. From bench work in research labs to industrial batch reactors and automated chemical platforms, the organic compound 8-Bromo-1-Octene plays a quiet yet valuable part in a range of innovations. Through my experience in laboratory synthesis and interacting with developers at specialty chemicals companies, I’ve found that certain molecules act as pillars in developing new pharmaceuticals, specialty polymers, and performance materials. 8-Bromo-1-Octene belongs to this group, offering chemists reliability along with performance.

    Where 8-Bromo-1-Octene Fits in the Chemical World

    Every lab order, every project launch, and each kilogram delivered to a pilot plant comes with a set of standards. For chemists and purchasing agents, 8-Bromo-1-Octene shows up as a clear, usually colorless liquid, with a molecular formula of C8H15Br and a structure featuring a terminal alkene at one end and a bromo substituent at the other. Typical purity levels exceed 97%, giving research and production groups a strong shot at predictable outcomes. Boiling at roughly 195 °C and weighing in at about 191 grams per mole, this molecule brings dependable physical and chemical characteristics to organic synthesis.

    Practicality matters a lot more than textbook or catalog descriptions. In my own lab experience, nothing stalls progress quite like a raw material that doesn’t behave as expected. 8-Bromo-1-Octene stands out partly because it does exactly what it’s supposed to—its reactivity comes from the combined presence of the reactive bromo group and the terminal double bond, opening doors to cross-coupling, substitution, and addition reactions that lie at the core of creating new molecules. Whether running a two- or three-step sequence in a fume hood or planning the scale-up of a new process, I’ve seen this compound provide clean conversions and good isolation yields, which translates to fewer headaches, less waste, and better economics.

    Focused Use in Synthesis and Material Science

    Many reagents serve a single, narrow niche. 8-Bromo-1-Octene breaks that mold. Over the years, scientists have leveraged it in the synthesis of specialty intermediates and performance polymers, surfactants, and even fine-tuned it for pharmaceutical research. In organic synthesis, its bifunctional structure means you can create long-chain intermediates that combine unsaturation (from the alkene) with a reactive leaving group (from the bromine). Professional curiosity led me to use 8-Bromo-1-Octene for Suzuki couplings, and I’ve watched colleagues plug it into ring-closing metathesis or build up complex macromolecules without much constraint. Its compatibility with standard reaction conditions frees up chemists to focus on design instead of troubleshooting.

    Chemistry in industry isn’t just about trial and error. Decisions come down to yield, cost, repeatability, and environmental impact. 8-Bromo-1-Octene delivers because it can undergo a variety of transformations under mild or standard conditions. For example, it can serve as an alkylating agent in the preparation of advanced intermediates or customized surfactants. In polymer materials, it’s found utility as a chain end modifier or a branching agent, letting synthesis teams create plastics and elastomers with tunable properties. I’ve seen several process chemists opt for 8-Bromo-1-Octene because its leaving group lets them introduce a precise carbon chain where other reagents either underperform or bring too much baggage, like heavy metals or unwanted byproducts.

    Real-World Chemistry and Accessible Handling

    Every researcher learns the value of workflow. In labs large and small, the right choice of starting material can be the difference between routine success and persistent difficulties. 8-Bromo-1-Octene’s chemical profile avoids frustrating problems common to less stable bromoalkenes. It remains stable in ordinary storage conditions—far from universal among bromoalkenes, which often darken or decompose on the shelf. That trait saves money and makes planning easier, whether batches are large or small.

    I’ve spoken with materials scientists who appreciate 8-Bromo-1-Octene because it blends into a wider range of organic solvents than many bromoalkenes, helping simplify method development and purification. No solvent system fits every lab, so a compound that keeps its cool with polar aprotic, nonpolar, or moderately polar solvents wins points for flexibility in both substance synthesis and product cleanup. Purification after reaction doesn’t bog down projects, since the liquid form and distinct boiling point lend themselves to conventional distillation techniques. That keeps resource needs realistic—no specialized equipment, no exotic controls—translating into fewer bottlenecks.

    Comparing 8-Bromo-1-Octene With Other Alkene Reagents

    Plenty of alkene reagents feature halogen atoms. Yet not all play nicely when subjected to real-world conditions. Take lower-bromoalkenes, for example. Shorter carbon chains can mean volatility, unpleasant odors, and difficult separations. High-molecular-weight bromoalkenes often become unwieldy; their solubility drops off, and they can resist common purification routes. Compared to those, 8-Bromo-1-Octene strikes a practical balance. Its moderate size fits well into both bench work and scalable industrial processes.

    If broadening reaction scope is the goal, longer-chain bromoalkenes appeal because they incorporate hydrophobic regions while packing in plenty of carbon atoms. That can be a plus for designing advanced surfactants, specialty lubricants, or tailored monomers. My own research teams have used competing bromoalkenes only to backtrack, since impurities left during synthesis or tough separations after reactions ate up time and budget. With 8-Bromo-1-Octene, those headaches tend to be rare.

    There’s also a difference on the shelf and in actual workflows. For instance, 1-Bromo-octane holds only a bromo group, lacking the double bond for further elaboration; conversely, 1-Octene lacks the functional leaving group needed for quick chain extension or haloalkylation. 8-Bromo-1-Octene delivers both—a terminal alkene and halide—combining them into a single, adaptable platform. This unique structure makes a difference every single day, letting chemists skip extra protection-deprotection steps and move on to the next phase of synthesis much sooner.

    Lab Safety and Responsible Chemistry

    Safety matters as much as reactivity when choosing a synthetic intermediate. From my own experiences overseeing undergraduate and graduate-level lab operations, 8-Bromo-1-Octene offers a comfortable risk profile relative to some specialty halides. It’s not excessively volatile, which cuts down on fume exposure. Common personal protective equipment—nitrile gloves, standard eyewear, and proper fume hoods—usually suffice to keep direct exposure low. 

    Of course, brominated compounds all carry certain hazards. User awareness and adherence to chemical hygiene standards keep incidents rare. In large-scale operations, sensible engineering controls and basic spill plans circumvent the majority of possible mishaps. Companies focused on sustainability appreciate that 8-Bromo-1-Octene avoids some of the byproducts generated by older halogenation chemistry, further minimizing environmental impact. Making sure that downstream waste streams are handled with responsible disposal methods helps reinforce sustainable practices. Many groups deploy closed-loop systems, solvent recycling, and neutralization steps tuned for bromine-containing organics.

    Why Purity and Traceability Matter

    Trust in raw materials is as vital to chemical synthesis as trust in a recipe is to a chef. Even one rogue contaminant can tarnish a month’s worth of results or a full production run. Most reputable vendors supply 8-Bromo-1-Octene with detailed certificates of analysis and supply chain documentation. I’ve dealt with suppliers who batch test every lot, confirming alkene content, bromide concentration, and absence of moisture or residual solvents. That practice not only boosts confidence among research chemists, but also helps meet tight regulatory or GMP requirements in pharmaceutical, electronics, and food-related industries.

    Traceability doesn’t just come from paperwork. Real-world lab validation rounds out the story. Thin-layer chromatography, NMR, and GC-MS let in-house teams check each delivery, reinforcing that the reagent’s composition lives up to its billing. The broader impact is straightforward: more repeatable science, fewer midstream surprises, and less troubleshooting when products move down the line. Whether developing a new drug molecule or a smart polymer film, knowing where every atom came from can be the difference between regulatory approval and a hard stop. It’s not overkill—it's what responsible chemistry looks like at scale.

    Regulatory Footing and Market Choices

    Anybody sourcing specialty chemicals juggles cost, supply continuity, and compliance. Regulations governing brominated intermediates have tightened over recent years, with oversight from agencies that look at workplace exposure and waste disposal alongside shipping rules. Research teams and industrial buyers balance the versatility of 8-Bromo-1-Octene against these realities. In my own procurement processes, well-sourced intermediates that don’t create extra paperwork or red tape move fastest from the PO to the lab bench.

    Manufacturers that put forth consistently pure 8-Bromo-1-Octene often invest in better batch control and tracking than low-cost suppliers operating in loosely regulated regions. More than once, I’ve seen cost-cutting on inputs backfire, leading to rejections and lost cycles on the production floor. For companies that operate in tightly regulated spaces—think parenteral pharmaceuticals or safety-critical specialty polymers—choosing a reliable reagent saves extensive auditing down the line. It isn’t just about getting a good price—it’s about protecting the mission and reputation of a project or a brand.

    Spotlight on Innovation and Future Prospects

    Tools that enable innovation have ripple effects. 8-Bromo-1-Octene’s structure makes it fertile ground for new catalytic techniques. Academics developing greener cross-coupling reactions often select it as a benchmark substrate—its stability and reactivity keep experimentation predictable, while the dual functional groups invite creative chemistry. Over the last five years, scientific literature has highlighted this molecule in metal-free catalysis, photochemical systems, and in developing recyclable surfactants that improve environmental performance. Having a reagent that encourages technical curiosity without creating cleanup headaches means more advances come to light.

    The sustainability side of specialty chemistry is evolving fast. More companies and institutions now track the full environmental impact and life cycle of their intermediates. Compared to older brominating agents and processes, 8-Bromo-1-Octene benefits from cleaner, more energy-efficient preparation methods. My dialogue with industry peers suggests that as regulations tighten on waste streams and product safety, materials that support easy downstream manipulation—like alkene removal or further functionalization—will win out. With its adaptable features, this compound has a place in greener process design, waste reduction efforts, and recyclable end products.

    Challenges, Limitations, and Responsible Strategies

    No chemical offers a universal solution. 8-Bromo-1-Octene doesn’t fit every synthetic route or end product; particular processes or sensitive functional groups may demand alternatives. Some users report that its volatility requires tight process controls in high-heat or open transfers, particularly at scale. Others contend with minor impurities that can complicate ultra-sensitive reactions, though vendor advances in purification have chipped away at those challenges. Safety teams still keep an eye on brominated byproducts, as waste regulations grow sharper.

    Solving these issues means more than swapping out reagents. Labs and plant processes benefit from continuous improvement—better monitoring for process drift, tighter batch analyses, and documentation routines that keep all parties in the loop. When issues pop up—such as odor, storage degradation, or byproduct formation—addressing them early through methodical troubleshooting remains key. In my experience, feedback from the production floor back to R&D has led to smarter tweaks: improved stabilizers, better seals on storage vessels, or advanced distillation protocols that lift more pure product and trim waste. Reagent suppliers who act on user feedback help raise the bar across the industry.

    Supporting Smarter, More Flexible Chemistry

    Science pushes forward by sharing successes and setbacks. For students and seasoned professionals alike, learning from real process data, safety notes, and user reviews of 8-Bromo-1-Octene sharpens the craft of chemistry. Manufacturer transparency—detailing where inputs originate and how they’re handled—reduces uncertainty and speeds up progress. Modern chemistry education now includes deep dives into reagent sourcing, trace impurity control, and life-cycle analysis as part of its core, because it reflects the world students will work in.

    Specialty intermediates like 8-Bromo-1-Octene show that even familiar molecules deserve close attention. Refining reaction steps, updating analytical tools, and keeping lines of communication wide open lets users get more out of each kilogram. Small changes—like switching a vendor or tweaking a purification procedure—can ripple through larger projects, driving improvements in safety, cost, and performance. As more research pivots to sustainability, using reliable, well-characterized building blocks ensures responsible progress, starting from the very first synthesis flask.

    Looking Ahead—Choosing with Confidence

    My own work in industrial and academic settings has taught me that choosing the right starting materials is a practical skill as well as a scientific one. 8-Bromo-1-Octene offers chemists, engineers, and innovators a time-tested, straightforward path to new molecules and materials. It has earned its spot not through flash or hype, but through the clear track record it brings to everyday science—good purity, accessible handling, clear documentation, and adaptability in both research and production. These qualities support repeatable progress, lower barriers to scale-up, and minimize troubleshooting along the way.

    Looking ahead, ever stricter regulatory frameworks and rising demands for responsible manufacturing will only reinforce the value of intermediates that combine adaptability with accountability. By sticking with proven suppliers, emphasizing best practices in storage and handling, and seeking out next-generation purification and analysis methods, the story of 8-Bromo-1-Octene remains one of utility and quiet reliability. Its versatility does more than fill a catalog slot: it helps shape safer, greener, and more efficient chemistry, project after project.