Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

7-Methoxy-4-Quinolinol

    • Product Name 7-Methoxy-4-Quinolinol
    • Alias 7-Methoxyquinolin-4-ol
    • Einecs 242-510-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    287450

    Chemical Name 7-Methoxy-4-Quinolinol
    Synonyms 7-Methoxy-4-hydroxyquinoline
    Molecular Formula C10H9NO2
    Molecular Weight 175.19 g/mol
    Cas Number 1420-68-8
    Appearance Light yellow solid
    Melting Point 194-197°C
    Solubility Slightly soluble in water
    Structure Quinoline ring with methoxy at position 7 and hydroxy at position 4
    Smiles COC1=CC2=CC(=O)C=CC2=NC1
    Inchi InChI=1S/C10H9NO2/c1-13-8-3-2-7-6-12-10(14)5-4-9(7)11-8/h2-6,12H,1H3

    As an accredited 7-Methoxy-4-Quinolinol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for 7-Methoxy-4-Quinolinol contains 25 grams, sealed in an amber glass bottle with a tamper-evident screw cap.
    Shipping 7-Methoxy-4-Quinolinol is shipped in tightly sealed containers, protected from light and moisture, and in compliance with chemical handling regulations. Packages are clearly labeled, with material safety data included. Standard shipping follows local and international guidelines for laboratory chemicals, ensuring safe transit and delivery to authorized laboratories or facilities.
    Storage 7-Methoxy-4-Quinolinol should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizing agents. Ensure the storage area is clearly labeled and access is restricted to trained personnel. Follow all relevant safety guidelines for handling organic chemicals.
    Application of 7-Methoxy-4-Quinolinol

    Applications of 7-Methoxy-4-Quinolinol in Industrial Manufacturing

    7-Methoxy-4-Quinolinol serves as a specialized intermediate for targeted use across several regulated industrial sectors. Its chemical properties enable direct incorporation into diverse manufacturing systems, with applications concentrating in pharmaceutical synthesis, agrochemical formulations, specialty dyes, analytical reagents, and advanced material science sectors. Each downstream path requires strict adherence to sector-specific quality and regulatory demands. Below we outline the principal industrial routes utilizing this compound, highlighting validated application criteria, manufacturing details, and end markets.

    1. Pharmaceutical Active Pharmaceutical Ingredient (API) Synthesis

    Pharmaceutical manufacturers apply 7-Methoxy-4-Quinolinol as a key building block during the synthesis of specific quinoline-derived APIs, particularly in antimalarial and anti-infective drugs. The compound often serves in regioselective substitution or condensation steps, ensuring precise control of molecular architecture in line with regulatory filings. Manufacturers rely on defined process parameters to minimize impurities and facilitate downstream purification steps, compliant with both local and international pharmacopeias.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • U.S. Pharmacopeia (USP)
    • European Pharmacopoeia (Ph. Eur.)
    • Chinese Pharmacopoeia (ChP)
    • FDA 21 CFR Part 211

    Typical usage ratio

    • 15-20% of the reaction mass in intermediate synthesis steps; adjusted based on API total molecular weight, reaction yield, and impurity profile targeting sub-0.5% byproduct formation.

    Downstream process integration

    • Input as a coupling agent or condensation starter in controlled reactor vessels after activating agents preparation, generally within closed-system GMP kilo-labs or commercial API lines.

    Final product types

    • Pharmaceutical APIs (e.g., antimalarial finished drugs)
    • Bulk intermediates for further API conversion

    2. Agrochemical Intermediate for Herbicide Synthesis

    Chemical processing plants incorporate 7-Methoxy-4-Quinolinol into the synthesis loop for several quinoline-based herbicides and pesticides. It plays a role as a critical intermediate molecule, offering site-specific activation for further derivatization. Facilities control reactions under strictly monitored conditions to meet regulatory thresholds for agrochemical grade purity and environmental compliance.

    Industry compliance standards

    • FAO/WHO JMPR agrochemical specification reports
    • REACH Regulation (EC) No 1907/2006 for chemical safety
    • ISO 9001-certified quality management system
    • China ICAMA registration requirements for technical material

    Typical usage ratio

    • 5-12% of initial batch input in synthesis of technical grade herbicides; final ratio depends on target molecular substitutions, solvent systems, and minimum residue criteria.

    Downstream process integration

    • Introduced into the reaction sequence after pre-chlorination or pre-nitration steps; often followed by alkylation or other functional group modifications, prior to formulation and granulation.

    Final product types

    • Quinoline-based herbicide technical concentrates
    • Agricultural active ingredient masterbatches

    3. Advanced Dye and Pigment Manufacturing

    Dye and pigment producers use 7-Methoxy-4-Quinolinol as a core intermediate for the development of high-performance quinoline dyes, employed in textile, leather, and specialty inks. The chemical’s methoxy and hydroxy functionality enables targeted chromophore extension and improved lightfastness. Production lines manage controlled addition to prevent unwanted polymerization and to comply with batch-to-batch color consistency requirements under global eco-label schemes.

    Industry compliance standards

    • ZDHC Manufacturing Restricted Substances List
    • OEKO-TEX Standard 100 (for textile dyes)
    • EU REACH Annex XVII for restricted colorants
    • ISO 9001-certified pigment batch traceability

    Typical usage ratio

    • 3-10% of total precursor mass, variable with target color strength, solubility, and viscosity in final dye paste formulations.

    Downstream process integration

    • Incorporated post-nitration in multi-step dye molecule assembly; further processed through sulfonation or complexation before dispersion and final blending.

    Final product types

    • Textile reactive and acid dyes
    • Capsule pigments for digital printing
    • Specialty ink concentrates

    4. Analytical Reagents and Chemical Standards

    Analytical chemistry suppliers and QC laboratories procure 7-Methoxy-4-Quinolinol to prepare certain high-purity analytical reagents, especially for fluorescence assays, metal ion detection, and standard curves in pharmaceutical and environmental monitoring applications. Material purity and trace contaminant levels are critical, qualifying the product for use in trace analysis and as a standard reference compound.

    Industry compliance standards

    • ISO 17034: General requirements for the competence of reference material producers
    • ISO/IEC 17025:2017 (testing and calibration laboratories)
    • Good Laboratory Practice (GLP, OECD)
    • Sigma-Aldrich quality management documentation for analytical standards

    Typical usage ratio

    • Typically prepared as 0.01-1% standard solutions or analyte spikes, with mass increments determined by instrument sensitivity and validation requirements for LC-MS, HPLC, and UV-Vis platforms.

    Downstream process integration

    • Converted to standard solutions by dissolution in HPLC-grade solvent or buffer, aliquoted for use in calibration, spiking, or recovery studies; implemented mid-stream in analytical QC workflows or end-of-line validation stages.

    Final product types

    • Analytical reference solutions
    • Calibrators for pharmaceutical testing
    • Environmental monitoring standards

    5. Polymer Additive and Specialty Material Modification

    Material science departments and polymer formulators utilize 7-Methoxy-4-Quinolinol as a chain-modifying additive in engineering polymer synthesis, such as in select polyimide, polyamide, or specialty copolymer products. Its incorporation enhances thermal and UV stability, features crucial for advanced electronics and automotive components. Formulators introduce the raw material in monomer blending steps under monitored thermal regimes, adjusting ratios based on desired functional group density and subsequent molding characteristics.

    Industry compliance standards

    • ISO 9001: Quality management for polymer compounding
    • RoHS Directive (2011/65/EU) for electronics-grade materials
    • UL 94: Safety of flammability for polymeric materials
    • ASTM D638 (Polymer tensile properties for qualifying batch modification)

    Typical usage ratio

    • Ranges from 0.5-3% by total monomer content; adjusted in pilot batches according to required polymer backbone modification, end-use certification, and performance benchmarks.

    Downstream process integration

    • Direct addition to monomer mixes during pre-polymerization, under inert atmosphere to preserve function groups, ahead of catalyst addition and chain extension steps.

    Final product types

    • Polyimide films for insulation
    • Functionalized engineering plastics
    • Automotive electronics encapsulation compounds
    Free Quote

    Competitive 7-Methoxy-4-Quinolinol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    What Sets Our 7-Methoxy-4-Quinolinol Apart

    Inside our production line, we keep a close watch on quality—not only because it matters for downstream chemical performance, but because the customers we serve rely on tight consistency. 7-Methoxy-4-Quinolinol takes careful handling at every stage, starting with precise raw material selection. This is no slapdash synthesis. Our team tracks every batch by high-performance liquid chromatography and n/p ratio checks to pin down the actual purity before anything moves from vessel to vessel. Many researchers and formulators come to us looking for the light yellow crystalline powder, confirming the signature melting point and UV spectrum because the work depends on it.

    Our Experience with Synthesis and Scaling

    The route we use for 7-Methoxy-4-Quinolinol synthesis runs years deep. After trialing several catalytic systems, we settled on a method that limits impurity carryover and scales up smoothly without running into yield cliffs or runaway reactions. Every large batch, we set aside reference samples from the start, midpoint, and final portions for in-house retesting and outside validation when needed. Through this, our team built a database of batch-to-batch performance and long-term stability—a comfort for anyone transferring lab discoveries into production settings.

    Some labs might focus on small-scale needs, delivering gram quantities with little trouble. As a manufacturer, we tackle metric ton scales and still keep within a tight purity range, keeping 7-Methoxy-4-Quinolinol above 99%. We manage moisture through closed-system handling and carefully tailored milling, since surface area can bump up sensitivity. On-site, our reactors allow us to customize the process for specialized runs that demand even finer control—eg, for pharmaceutical synthesis or advanced intermediates.

    Real-World Usage Informed by Decades on the Floor

    Chemists reach for 7-Methoxy-4-Quinolinol for a handful of good reasons. Its methoxy group resists hydrolysis under typical storage, while the quinolinol framework supports strong chelation, aromatic substitutions, and ring-closure reactions. For antimalarial research, the compound stands as a core structure, providing a scaffold for further functionalization. In agrochemical development, it serves as both intermediate and analytical reference compound, supporting SAR studies that can determine next steps in lead optimization. Dye makers and photochemistry groups value the stability under ambient light and mild acidic conditions. They come asking about our controls on side-products—because in photoreaction design, one methyl off in a contaminant can blow apart spectra.

    Over time, we’ve noticed that storage, not just initial purity, changes user experience. Our team built out dedicated rooms with air control to keep 7-Methoxy-4-Quinolinol in peak form over months, instead of watching it dull or degrade due to ambient humidity. Not every plant spends this kind of time managing supply chain risks, but from our experience, a sudden spike in water content can wreck downstream yield or catalysis performance.

    Why Specific Model and Specifications Matter

    There’s a lot of chatter about ‘pharmaceutical grade’ and ‘industrial grade’ labels. We’d rather talk specifics. Our model YQ-0760 batch delivers material at 99.2% confirmed by three in-house techniques: HPLC, mass spec, and qNMR. Ash levels rarely break 0.03%, and we verify trace metals to ensure each lot meets the food and pharma input requests. For specialty electronics and OLED customers, our team prepares a secondary high-purity version, sieved to sub-millimeter particle size and double-vacuum dried. Tailoring specs came about through direct user feedback, not guesswork, and we’re happy to apply additional quality assays whenever new applications surface.

    What does this mean in real practice? If a pharmaceutical firm runs an alkylation step, trace iron from a careless synthesis batch can shut down a catalyst system or require extra purification. If a coatings company needs a sharp color cutoff in their UV stability tests, just a tick above 0.1% impurity can drift results and pass undetected by lower-resolution QA. By tightening our own processes, we save other plants time—and save countless research hours redoing analyses.

    Comparing 7-Methoxy-4-Quinolinol With Other Building Blocks

    We field plenty of questions about substitutions for 7-Methoxy-4-Quinolinol. Some try 4-hydroxyquinoline or 7-chloro-4-quinolinol, but the altered ring electronics often change reaction paths, affecting yields or selectivity. The methoxy at the seven position brings a unique balance—not so bulky as to hinder substitution, but still electron-donating enough to steer ring reactivity. That means our customers can plan Friedel-Crafts or condensation reactions with predictable outcomes. It also means less risk for unusual isomerization, which anyone running multi-step synthesis will appreciate.

    Users also appreciate the way 7-Methoxy-4-Quinolinol handles during blending or reaction setup. While some analogs form compact cakes or dust heavily, our product stays consistent—due in large part to careful drying and packaging, plus tight analysis before sealing. Some makers cut corners on final handling, which can leave buyers dealing with clumpy or partially degraded batches. We insist on full batch tracking; barcoding and lot-level QA sampling make a difference that shows up not only at delivery but during months of lab or production storage.

    Insight Into Our Quality Control Journey

    Every plant talks quality, but let’s be honest—most headaches come from avoidable slips. In our own early days, we saw what happened when moisture readings drifted during the summer or raw solvent lots showed trace contamination. We caught it from long-time customers, and after enough digging, reset our entire process flow. Today, we assign a trace manager to every large-batch run. This person follows raw materials from entry to finished product, noting batch changes, documenting conditions, and double-checking QC signoffs. For a compound like 7-Methoxy-4-Quinolinol, where cost per kilo can make or break project budgets, that consistency translates to real savings downstream.

    We also invite third-party verification twice a year, mixing surprise spot checks with routine reviews. During a recent audit, the outside team flagged a minor spike in potassium ion trace in one corner of the synthesis line. Our techs found the culprit—a pump head with a subtle seal leak. Catching that early kept us well under our usual thresholds and confirmed for our buyers that our claims aren’t just marketing.

    Feedback from Long-Term Users

    Most new buyers come to us by way of referral or speak with peers about their results. One lab in Europe reported that their yields in quinolinone synthesis rose 4% after switching to our batches, attributing the change to the lack of byproduct fluorescence interfering with their endpoint readouts. An Asian pharmaceutical plant documented smoother filtration performance; their pre-treatment step for the methoxyquinolinol included a pressure-differential test, which our powder cleared with no bridging or slumping—a mark of fine-tuned particulate control.

    We also hear from diagnostics groups testing new markers. A North American customer shared how their initial batches from other sources came speckled with yellowed debris, affecting downstream imaging. Our material, kept under inert atmosphere and packed under laminar flow, gave them a stable baseline for multiple runs. These details—minor in some minds—build the confidence asset managers look for before they switch longtime suppliers.

    Our Take on Responsible Manufacturing

    Manufacturing isn’t all about pushing out volume. Environmental responsibility matters, and as quinoline compounds ride under scrutiny for ecological persistence, we’ve made it a standard to treat process wastewater and recycle solvents beyond local legal minimums. In one recent year, we cut our chemical input costs by reclaiming and re-distilling site solvent streams. No government agency forced this—years of seeing the waste cut into margin and impact local rivers prompted the upgrade.

    Our waste capture systems now run with double-sealed transfer lines and real-time leak detection. This keeps our operators safer and guarantees the powder our customers receive wasn’t cross-contaminated anywhere along the journey. Temperature and humidity control aren’t just boxticks—they mean that what leaves our floor matches the spec sheet in both content and physical properties.

    Troubleshooting Customer Challenges with 7-Methoxy-4-Quinolinol

    A lot of companies call for technical support not due to failures with the product as produced but because process adaptation hasn’t followed best practice. For example, suppliers without experience managing methoxyquinolinol can struggle to blend it into solvent without forming microinclusions or slow-dissolving particles. Our technical team frequently shares preparation protocols—including solvent preheating steps, agitation profiles, and filtration screen choices. These can sound like minor fiddles, but in our experience, they avoid hours lost hunting impurities or wondering about batch-to-batch variability.

    Another frequent pain point: interface with automated dosing systems. Because 7-Methoxy-4-Quinolinol can static charge or clump if transferred in low-humidity, high-airstream lines, we recommend (and offer) antistatic treated liners for plants using automated dispensers. Several high-throughput users found that their yield variability disappeared after switching to this approach. Sharing lessons like this supports not only customer satisfaction but lifts the whole discipline, as findings ripple from one user to the next.

    Regulatory and Downstream Confidence

    With traceability growing more important in supply chains, we’ve embedded digital batch records and secure archiving for every kilogram. Analytical data, origin tracing, and retention time profiles stay accessible for years after dispatch, meaning a compliance or recall issue never turns into a panic. Regulatory shifts happen quickly, but with our hands on the pulse of local and global change, we adjust routes and documentation as incoming laws demand. By keeping our runs open for audit, from input solvents to final railcar shipment, we help our buyers sleep better—knowing every bottle or drum connects seamlessly with what’s required downstream.

    Continuous Improvement and Next-Generation Use

    Research never stays still, and we see new needs emerging every year. As CRISPR gene editing and targeted therapies rise, we’ve fielded inquiries for 7-Methoxy-4-Quinolinol in bioconjugation routes, sensitive labeling, and controlled release matrix studies. While the core synthesis remains solid, our R&D team co-develops purification tweaks for specialist partners, aiming for the kind of trace sterility that can open new drug product doors.

    Even outside pharma, electronics and battery experts request ultra-low-impurity grades for energy storage and current collector coatings. Drawing on our decade-long compositions library, we run pilot-scale splits, open the findings to our partners, then invest in new handling or drying systems as the science demands. Real, on-the-floor collaboration keeps our product aligned with new frontiers—not fossilized in “good old days” thinking.

    Concluding Thoughts from the Production Line

    Every kilo of 7-Methoxy-4-Quinolinol that ships out tells a story: how a global team, rooted in practical chemical experience, makes choices about synthesis, purity, and support because of real-world demands. We see, day by day, that diligent manufacturing doesn’t just fill orders. It lays the groundwork for safer, more effective products—whether in the lab, the factory, or in tomorrow’s treatments. That’s not marketing copy—it’s simply what years on the production line reveal about what truly matters in delivering a reliable specialty chemical.