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7-Bromo-1-Heptene

    • Product Name 7-Bromo-1-Heptene
    • Alias 1-Bromo-7-heptene
    • Einecs 211-813-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    663278

    Name 7-Bromo-1-Heptene
    Molecular Formula C7H13Br
    Molar Mass 177.08 g/mol
    Cas Number 41135-09-1
    Appearance Colorless to pale yellow liquid
    Boiling Point 58-60°C at 10 mmHg
    Density 1.159 g/cm³
    Refractive Index 1.466-1.470
    Flash Point 52°C
    Purity Typically >97%
    Solubility In Water Insoluble
    Smiles C=CCCCCCBr
    Inchi InChI=1S/C7H13Br/c1-2-3-4-5-6-7-8/h2H,1,3-7H2

    As an accredited 7-Bromo-1-Heptene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Clear glass bottle containing 100 grams of 7-Bromo-1-Heptene, securely sealed with a red screw cap and labeled with safety information.
    Shipping 7-Bromo-1-Heptene is shipped in tightly sealed, chemical-resistant containers to prevent leaks and contamination. Packages are clearly labeled and handled according to applicable safety and hazardous materials regulations. Transportation complies with local and international standards, ensuring safe delivery while minimizing the risk of exposure or environmental release during transit.
    Storage 7-Bromo-1-Heptene should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. Protect from direct sunlight and moisture. Proper labeling and secondary containment are recommended to prevent leaks or spills. Use appropriate personal protective equipment when handling and ensure compliance with safety regulations.
    Application of 7-Bromo-1-Heptene

    Applications of 7-Bromo-1-Heptene in Industrial Manufacturing

    7-Bromo-1-Heptene serves as a specialized chemical intermediate in the synthesis of advanced organic compounds. With its reactive allylic bromide structure, it enables downstream producers to introduce unique carbon chain modifications, especially for industries requiring precision in molecular design, purity control, and compliance with stringent regulations. Below, we outline verified application sectors where 7-Bromo-1-Heptene finds real-world use in demanding manufacturing routes.

    1. Pharmaceutical Active Ingredient Synthesis

    In pharmaceutical intermediate manufacturing, this raw material plays a crucial role in the preparation of drug precursors, especially for molecules where straight-chain heptyl moieties or further functionalization of the olefinic position is needed. Its brominated terminus facilitates nucleophilic substitution and cross-coupling reactions for the construction of pharmacologically active scaffolds, supporting multi-step synthesis under cGMP and ICH Q7 regulations. Our controlled supply chain and QC system ensure that the material meets the rigorous trace impurity and residual solvent specifications required by leading pharma customers.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (Ph. Eur.) guidelines for intermediates
    • U.S. FDA 21 CFR Part 211 for process controls and purity
    • Qualified Person (QP) audit requirements in Europe

    Typical usage ratio

    • Commonly 0.7–1.2 molar equivalents relative to target intermediate, adjusted based on substitution efficiency and batch reactor charging protocols

    Downstream process integration

    • Added during the nucleophilic alkylation or cross-coupling step, often after initial ring closure or carbonyl introduction phases
    • Requires anhydrous conditions and controlled temperature using jacketed reactors with online LC-MS monitoring for completion

    Final product types

    • Key intermediates for antihypertensive APIs
    • Precursors for antiepileptic and neuroprotective agents
    • Building blocks for selective hormone analogues

    2. Agrochemical Intermediate Production

    Manufacturers of crop protection agents use this compound to introduce specific alkyl groups in the synthesis of new-generation insecticide and fungicide molecules. Its distinct halogen functionality allows for effective coupling in producing long-chain derivatives, crucial for enhancing bioactivity and environment-targeted persistence. Facilities with advanced hazardous handling protocols integrate this material into final-stage intermediate synthesis for registered actives, prioritizing compliance with both REACH and FAO specifications.

    Industry compliance standards

    • Regulation (EC) No 1907/2006 (REACH) for supply chain traceability and CMR classification
    • Food and Agriculture Organization of the United Nations (FAO) Specifications for technical grade material
    • ISO 9001:2015 for process management and batch traceability
    • OECD Guidelines for the Testing of Chemicals (section 3: pesticide intermediates)

    Typical usage ratio

    • Applied at 1.05–1.25 equivalents per mole of aldehyde or ketone substrate, with optimization based on LCA and yield targets

    Downstream process integration

    • Incorporated during nucleophilic substitution or Heck coupling after initial halogenation sequence, utilizing glass-lined reactors with dedicated venting systems
    • Residue minimization via batch distillation and multi-stage vacuum purging prior to final crystallization of intermediates

    Final product types

    • Substituted alkene intermediates for pyrethroid insecticides
    • Building blocks for systemic triazole fungicides
    • Fine intermediates for selective herbicide actives

    3. Synthesis of Specialty Silicone Modifiers

    Downstream silicone product plants rely on this material for introducing terminal heptyl groups via hydrosilylation modified with brominated alkenes. This approach enables the preparation of siloxane fluids with improved chain flexibility, oil repellency, and tailored spreading properties on diverse substrates. Our customized lot segregation and low-metal content guarantee the input meets specialty silicone modifier protocols, as demanded by global leaders in release coatings and high-temperature lubricants manufacture.

    Industry compliance standards

    • ASTM D1135 for silicone fluid composition
    • ISO 9001:2015 for specialty chemical production lines
    • REACH pre-registration for precursor hazard labelling
    • RoHS Directive 2011/65/EU for brominated content

    Typical usage ratio

    • Ranges from 2–8% by mass relative to starting hydrosilane, with batch-specific adjustments to viscosity or surface property targets

    Downstream process integration

    • Fed at the alkene addition stage using platinum-catalyzed hydrosilylation in pressure-controlled, inert atmosphere vessels
    • Post-reaction vacuum stripping to eliminate unreacted materials and achieve tight residual bromine specification

    Final product types

    • High-performance release coatings for industrial paper and film
    • Custom silicone fluids for electronics thermal management
    • Surface-active agents for automotive lubricants

    4. Cationic Surfactant Intermediate Processing

    Producers of alkyl-substituted quaternary ammonium compounds utilize this raw material to create bespoke surfactants with extended hydrophobic chains, enhancing antimicrobial properties without compromising biodegradability. Its direct bromine leaving group supports efficient quaternization with tertiary amines in closed-system reactors. Factories with zero liquid discharge infrastructure favor this option for surfactant applications compliant with environmental and food contact norms, especially in the preparation of process aids and disinfectant actives.

    Industry compliance standards

    • U.S. EPA Safer Choice Standard for surfactant intermediates
    • OECD 301 biodegradation protocol
    • Regulation (EU) No 2019/1021 (POPs Regulation) for surfactant safety
    • Food Contact Materials Regulation 10/2011/EU—where applicable in cleaning aid applications

    Typical usage ratio

    • Typically 1.0–1.1 equivalents per tertiary amine, controlled based on titrimetric endpoint and downstream purity targets

    Downstream process integration

    • Introduced during the quaternization reaction in charge-sequenced, stirred tank reactors equipped with online bromide monitoring
    • Enacts phase transfer catalysis to cap the hydrophobic chain with minimal byproduct formation

    Final product types

    • Industrial cleaning aids for textile and metal treatment
    • Functional surfactants for emulsion polymerization
    • Environment-friendly antimicrobial and disinfectant bases
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    Certification & Compliance
    More Introduction

    Introducing 7-Bromo-1-Heptene: Experience, Production, and Industry Insights

    Our Approach to 7-Bromo-1-Heptene

    Working day in and day out on halogenated alkenes has taught us the importance of getting every step right, from the raw materials up through the purification. In our facility, 7-Bromo-1-Heptene production backs up to strict synthesis parameters, starting with carefully monitored selections of 1-heptene and brominating agents. This alkene, with its single bromine substituent at the seven position, serves as an anchor in specialty syntheses. Our process prioritizes not just yield but the consistency and purity profiles demanded by experienced downstream users, helmed by chemists and engineers who know what impurities can do to a reaction route.

    Practically, a batch runs only after targeted checkpoints clear—beginning with a phase-controlled bromination that targets the desired product versus dibromo side reactions. From there, rigorous distillations and purifications strip out isomers and byproducts. Customers look for a clear, essentially colorless liquid that meets tight GC purity requirements, typically exceeding 98%. In practice, we run periodic impurity profiling far past the minimums, proactively catching lot-to-lot variation early, not after complaints roll in.

    The Role of 7-Bromo-1-Heptene in Modern Synthesis

    The main reason industry professionals choose 7-Bromo-1-Heptene over structurally close compounds lands on the terminal bromine. With a bromine atom on the far end of a seven-carbon straight chain, this molecule holds significant value as a versatile alkylating agent. We have longstanding partners in pharmaceutical, agrochemical, and fine chemical companies who find the C7 chain ideal for building blocks in advanced intermediates, specialty monomers, and even some flavor or fragrance actives.

    Those who’ve run complex coupling reactions know the difference between handling a well-made halogenated alkene and wrestling with side cuts, unreacted feedstock, or incompatible counterions. 7-Bromo-1-Heptene’s terminal alkenyl structure provides chemoselectivity—an advantage over secondary or internal bromides. The reactivity lands at a sweet spot for many cross-couplings, especially Heck, Suzuki, and palladium-catalyzed reactions, where excessive branching or internal placement can suppress desired conversions.

    Beyond the basic coupling reactions, downstream users exploiting the double bond often apply hydrofunctionalization or metathesis. For teams exploring polymers or specialty surfactants, this terminal unsaturation offers a feedstock option that opens routes less available with brominated alkanes or internal alkenes. We see steady growth among formulators who modify the heptenyl backbone, creating unique surfactant tail groups or plasticizers.

    The Details That Separate Our 7-Bromo-1-Heptene

    The production process we use is grounded in decades of hands-on chemical processing. Our reactors run closed, nitrogen-blanketed lines to control moisture and oxygen pickup, which reduce peroxide formation and yellowing in storage. The tools might read old-school—glass reactors, precision temperature control, staged additions—but the results land peak performance. Purification relies on phase separation and high-efficiency column distillation, avoiding excessive isomerization caused by uncontrolled heat. We regularly test for common contaminants: dibromoheptanes, undehalogenated heptene, and traces of short-chain bromides. GC and NMR spectra guide each lot’s release.

    As a producer, we’ve learned customers recognize the difference once they’ve tried a reactive intermediate that meets grade, not just spec. Solubility, absence of haze, and minimized odor all track to better shelf stability. We store and ship only in new HDPE drums or fluorinated containers, capped against leakage and vapor loss—a lesson from early runs that didn’t account for the material’s volatility.

    Comparing 7-Bromo-1-Heptene to Other Bromoalkenes and Bromoalkanes

    Lab-scale synthesis can use almost any halide if purity isn’t a big concern, but the reality in production environments is different. Chlorinated analogues tend to be less reactive in many common coupling reactions, requiring stronger bases or harsher conditions that introduce byproducts. Competing bromoheptene isomers—where the bromine lands internally, not terminally—risk branching off into unwanted byproducts, especially if your downstream route depends on the chain length staying intact.

    Brominated alkanes with no double bond simply won’t yield the same range of derivative chemistry. We’ve fielded questions about using 1-Bromoheptane or 2-Bromoheptene as cheaper alternatives, but our experience—and those of repeat customers—shows these substitutions cost more in lost yield and extra purification than they save in raw materials. Polymers dependent on terminal functionalization cluster tighter around 7-Bromo-1-Heptene thanks to its predictable end-group chemistry.

    Many bromoalkenes bring regulatory headaches or storage concerns due to instability or off-gassing. We learned early to control stabilization—never overuse inhibitors, though, as these can poison catalysts or complicate downstream processing. Our specification omits nonessential stabilizers, relying instead on rapid turnover and tight warehousing practices.

    Supporting Custom Applications and Formulation Needs

    We work directly with chemists who need modifications to neat 7-Bromo-1-Heptene—extra purification, fractionated batches, or solvent blends for specific reactors. After years fielding requests, we developed multistep QC to make sure every tweak delivers measurable benefit. If the application calls for higher than standard purity, extra GC and moisture analysis head each lot. A few clients building active pharmaceutical intermediates or specialty agrochemicals request customized material certificates, not just an off-the-shelf sample. Our technical staff are production-side, not just on the sales end, so feedback from the plant often shapes what we offer next time.

    Some downstream formulations need a fixed moisture band; for that, we vacuum strip and nitrogen pack each drum before shipment. If a process route can’t tolerate trace acid (from minor HBr hydrolysis), we apply custom neutralization right at the point of fill, not weeks before. Each detail reflects feedback—direct, blunt, and informed—from chemists running real reactions, not just desk pilots.

    Storage, Handling, and Real-World Transport Concerns

    Few things frustrate a formulator more than opening a long-awaited drum only to find product colored or partially polymerized. 7-Bromo-1-Heptene ships on weekly cycles, never sitting for months in hot storage. We employ data loggers in warehouses to monitor ambient humidity and temperature, catching issues before outbound shipments. Secondary packing uses vapor-tight liners to avoid spills and evaporation, a lesson learned the hard way by anyone who’s ever handled volatile organohalides.

    Onsite, chemists often ask about material transfer and compatibility. Our experience finds fluorinated valves hold up far better than brass or steel, and every drum ships with clear, practical instructions—not generic warnings. After several years supporting active plant sites, we maintain a feedback loop from customer warehouses to our filling room, addressing batch-specific problems as fast as possible.

    Ensuring Compliance and Safe Use

    As regulatory expectations change, our response remains grounded in direct lab monitoring and adaptation. 7-Bromo-1-Heptene doesn’t fall into the class of highly restricted chemicals, but standards for workplace and environmental exposure tighten every year. Our internal compliance sits squarely with routine monitoring on bromide emissions and waste byproducts. Disposal routines reflect current best practices. We keep careful logs on every shipment, covering origin, batch, and destination, as required by responsible chemical stewardship.

    We don’t just hand over a drum or tote and wave away responsibility. Years of visits to user sites revealed that overlooked details—from secondary containment to venting and PPE—mean more for long-term safety than any clause in a standard sheet. End-users growing their consumption can always consult with our in-house safety staff, who have seen both worst cases and best practices in the field.

    Long-Term Quality and Continuous Improvement

    In the specialty chemical landscape, trends come and go: new cross-coupling catalysts, greener reaction conditions, digital plant controls. 7-Bromo-1-Heptene has shown staying power as a fundamental intermediate. We invest in maintaining process equipment—reactors, packing, and cleanroom grading—as standards rise. Internal audits push us to probe every step for tighter control, not just larger volumes.

    Any product left to drift loses competitive edge. We keep close track of customer-submitted data—yields, off-spec runs, reaction time—wrapping these insights back into both upstream synthesis and downstream support. Modifications aren’t just theory: every time a major processor requests a modification, we use pilot-scale runs before shifting plantwide. In the last few years, changes in purification have shifted slightly to address changes in paired catalyst systems and analytical demands.

    Innovations filter consistently from bench scale to production. We encourage field feedback on solvent compatibility, catalyst sensitivity, and shelf life, redirecting lab development to focus on concrete, user-reported challenges. Bottlenecking at the point of blending or metering is documented and driven into both process improvement and logistics tweaks at our end.

    Serving Clients of All Scales: Lessons from Diverse Demand

    Not every customer operates a multi-ton facility or even an in-house analytical lab. We field small-lot and pilot-scale requests frequently and respect the unique demands of each. For low-volume innovators—startups, research arms, and custom product developers—we supply tailored lot sizes, responding swiftly to changes in demand forecasts.

    At the other extreme, for global players needing scheduled, scalable logistics, our team handles drum-level dispatch up through container-sized repeat orders. By continually refining forecasting and logistics, we help minimize downtime and excess storage at client sites. From feedback, we know this direct connection makes the difference between a reliable supply chain and an unpredictable hassle.

    Direct lines from production floor to customer avoid confusion and delay; no middlemen, no secondhand status updates. This responsiveness has shaped how we operate, shaping both how we staff customer support and how our plant schedules capacity.

    Interpreting Market Shifts and Responding to Industry Trends

    Industry trends over the last decade show a rising preference for longer-chain, functionally differentiated alkenes as regulatory scrutiny on short- and medium-chain halocarbons tightens. Environmental pressure on persistent, volatile halogenated compounds has led us to adopt closed-loop containment and greater process integration. We proactively address new regional requirements as industry shifts accelerate, not waiting for last-minute regulation to drive improvements.

    Most new applications arise where flexibility in chain length or terminal reactivity counts. As innovation pulls research toward specialty coatings, next-generation polymers, or green formulations, the precise control over the bromoalkene’s placement—both on the chain and on the molecule—drives the choice. Our plant’s flexible setup enables specification changes or new derivative runs that keep up with current trends without lagging behind.

    The market rewards those willing to retool and reinvest: in recent years, we’ve devoted capital and training into reaction engineering and on-premise analytical support, not just upstream scale. Questions focused on regulatory status, carbon chain traceability, and downstream waste have moved upstream into our production routines, ensuring customers can make informed choices with material that goes beyond the datasheet.

    Challenges and Solutions in Bromoalkene Sourcing

    Every chemical plant eventually hits bumps sourcing precursors—price fluctuations, purity swings, or logistical hiccups. Over years of operation, we’ve diversified our raw material base, qualifying secondary suppliers and performing cross-lot blending if required. Earlier in our history, reliance on single-source brominating agents risked delays, which taught us the value of redundancy.

    Customers often ask about price volatility and uninterrupted supply. We hold safety stocks with climate-controlled warehousing and run parallel synthesis lines so that operational downtime in one reactor doesn’t sideline a week’s orders. Our experience shows downstream operations value predictability over minor pricing dips: it prevents wasted labor, reformulation, and lost business.

    Changing environmental policies ripple back into supply and demand for intermediates like 7-Bromo-1-Heptene. We stay ahead by maintaining strategic reserves and by rapidly qualifying alternative precursors or process revisions. Early transparency about lead time risks and open communication on timelines has forestalled headaches on both sides.

    Hands-On Support and User Engagement

    Direct engagement defines our philosophy. User site visits and facility audits, from our technical team, break down the workflow barriers that generic customer service lines can’t climb. Our organization prioritizes technical dialogue—chemists and engineers routinely address bottlenecks and offer troubleshooting based on firsthand plant experience, not boilerplate advice.

    Collecting and applying practical user feedback creates a loop that benefits both ongoing production and future innovation. We investigate cause when a plant reports a reaction stall or unexpected impurity, cycling that information through both process control and raw material approval. Major users often invite us for in-person reviews, and this collaboration has steered hundreds of improvements in reaction windows, fill procedures, and purity checks.

    Looking Ahead with 7-Bromo-1-Heptene

    Every year, new applications for terminal bromoalkenes emerge from old reaction blueprints dusted off, or novel directions pursued by research labs and industry pioneers. Whether 7-Bromo-1-Heptene enters a pharmaceutical synthesis, a specialty polymerization, or an advanced surfactant blend, our team has seen every usage scenario shaped by real-world demands.

    What sets our approach apart is commitment to improvement, open lines to the plant floor, and direct engagement with users. Bypassing layers of distribution means fast responses, reliable supply, and hands-on support for every batch and every end use. As 7-Bromo-1-Heptene continues to evolve in new fields, our operation adapts with it, embedding years of chemical manufacturing experience into every shipment.