Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

6-Methoxy-2-Naphthol

    • Product Name 6-Methoxy-2-Naphthol
    • Alias 6-Methoxy-2-naphthalenol
    • Einecs 218-954-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    691354

    Chemical Name 6-Methoxy-2-Naphthol
    Cas Number 3076-51-9
    Molecular Formula C11H10O2
    Molecular Weight 174.20 g/mol
    Appearance White to off-white solid
    Melting Point 134-137°C
    Boiling Point Unknown
    Solubility Slightly soluble in water, soluble in organic solvents
    Synonyms 2-Hydroxy-6-methoxynaphthalene
    Pubchem Cid 24501
    Smiles COC1=CC2=C(C=CC(=C2)O)C=C1
    Inchi InChI=1S/C11H10O2/c1-13-9-4-2-3-7-5-6-10(12)11(7)8(9)9-4/h2-6,12H,1H3

    As an accredited 6-Methoxy-2-Naphthol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams of 6-Methoxy-2-Naphthol; label displays chemical name, CAS number, and hazard symbols.
    Shipping 6-Methoxy-2-Naphthol is shipped in tightly sealed, chemically resistant containers to prevent moisture and light exposure. The packaging complies with relevant safety regulations, with clear labeling of chemical identity and hazard information. Standard couriers specializing in chemical transport ensure controlled conditions and prompt delivery, minimizing risk during transit.
    Storage 6-Methoxy-2-Naphthol should be stored in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizing agents. Protect it from light and moisture. Store at room temperature and avoid excessive heat. Ensure proper labeling, and keep away from ignition sources. Follow all relevant safety and regulatory guidelines for storage.
    Application of 6-Methoxy-2-Naphthol

    Applications of 6-Methoxy-2-Naphthol in Industrial Manufacturing

    6-Methoxy-2-Naphthol is an important fine chemical intermediate used by manufacturers across specialty dye, pigment, pharmaceutical, and chemical synthesis sectors. As a raw material producer, we supply this compound to directly support scalable production lines with consistent batch performance, traceable quality assurance, and industry-specific formulations. Below, we detail the principal industrial applications, each illustrated with practical integration, regulatory context, recommended dosage, and typical final product types.

    1. Azo Dye Intermediates for Textile Colorants

    Textile dye manufacturers employ 6-Methoxy-2-Naphthol primarily as a coupling component during the diazo coupling phase for synthesizing bright, stable azo and anthraquinone class colorants. Its electron-donating methoxy group confers enhanced dye bath fastness and wash durability. The intermediate is introduced post-diazonium salt generation and forms the chromophoric center essential for deep red and purple hues in synthetic fibers and blended fabrics.

    Industry compliance standards

    • ZDHC (Zero Discharge of Hazardous Chemicals) Manufacturing Restricted Substances List
    • OEKO-TEX® Standard 100, Annex 4 for dyestuff safety
    • REACH Regulation (EC) No 1907/2006 for chemical registration and SVHC monitoring
    • ISO 105 C06 for color fastness assessment in textiles

    Typical usage ratio

    • 5%–12% of the dye formula mass, calibrated based on target shade strength, chroma level, and batch scale; light shades use less, while deeper shades require higher content.

    Downstream process integration

    • Added during the azo coupling stage after diazotization, in stirred reactors under mild alkaline conditions; subsequent filtration and spray-drying precede formulation into dust-free granules or powder blending.

    Final product types

    • Disperse and acid dyes for polyester and nylon
    • Direct dyes for blended cellulose fabrics
    • Sulfonated azo colorants for inkjet and digital textile inks
    • Pigment dispersions for technical textile coatings

    2. Pigment Chemical Synthesis for Plastics and Coatings

    Aromatic pigment manufacturers utilize 6-Methoxy-2-Naphthol in the synthesis of complex naphthol-based pigments, particularly for engineering plastics, automotive paints, and powder coatings. The methoxy substitution enhances thermal stability and light resistance, making it suitable for high-end pigments subjected to elevated processing temperatures. It serves as a key reactant during nucleophilic condensation and ring fusion reactions.

    Industry compliance standards

    • EN 71-3:2019 (European Toy Safety for pigments in children’s products)
    • ASTM D476 for classification of pigments
    • FDA 21 CFR 178.3297 for colorant use in polymers in contact with food
    • ISO 9001-certified pigment ingredient traceability

    Typical usage ratio

    • Usually 3%–10% of the pigment precursor blend, adjusted according to targeted color index (CI), required migration fastness, and process yield; higher levels for high-opacity masterbatch pigments.

    Downstream process integration

    • Charged in the raw mix before cyclization and fusion reactions; post-coupling, intermediates are milled, purified, and subjected to finishing for dispersion optimization before blending with resins or polymer carriers.

    Final product types

    • High-performance organic pigments for casting resins
    • Color concentrates for injection-molded plastics
    • Exterior automotive and marine coatings
    • Biocide-free pigment pastes for children’s art materials

    3. Pharmaceutical Intermediate for Antifungal APIs

    In pharmaceutical manufacturing, 6-Methoxy-2-Naphthol acts as a building-block intermediate in the synthesis of select antifungal active pharmaceutical ingredients (APIs), particularly for topical creams and medicated liquids. It undergoes Friedel–Crafts and O-alkylation reactions as part of multi-step API routes, directly impacting the safety, purity, and batch reproducibility of regulated pharmaceutical end products.

    Industry compliance standards

    • Current Good Manufacturing Practices (cGMP, ICH Q7)
    • US Pharmacopeia (USP) and European Pharmacopoeia (Ph. Eur.) for intermediate controls
    • ISO 9001:2015 for QC batch release
    • DMF (Drug Master File) submission for active intermediates

    Typical usage ratio

    • Molar equivalent as needed in the route—typically 0.8 to 1.2 molar ratio relative to the starting scaffold, finely tuned by process chemists based on API yield and impurity profile.

    Downstream process integration

    • Charged during the key intermediate synthesis stage, often after initial scaffold construction and prior to ring-closure or alkyl substitution; purification steps follow with solvent washes and crystallization before forwarding to final API synthesis.

    Final product types

    • Active intermediates for topical antifungal (e.g., naphthol-ether azoles)
    • Precursors for further glycosylation/hydroxylation in semi-synthetic APIs
    • Finished antifungal solution and ointment bases
    • Blister-packed medicated creams

    4. Chemical Intermediate for Synthesis of Specialized Agrochemical Compounds

    Agrochemical formulators incorporate 6-Methoxy-2-Naphthol in tailored synthesis pathways for specific naphthol-derived fungicide and pesticide active ingredients. Its aromaticity and substitution pattern make it suitable for constructing conjugated ring systems in broad-spectrum crop protection agents. Typical use occurs in multi-step synthetic schemes targeting improved field stability and environmental safety.

    Industry compliance standards

    • FAO/WHO specification for pesticide technical materials
    • ISO 17025-guided in-process testing and QC
    • GLP (Good Laboratory Practice) for scale-up validation
    • REACH (EC) No 1907/2006 registration for agrochemical intermediates

    Typical usage ratio

    • Ranges between 2%–5% of total reactant mass in the batch, modulated based on target molecule structure, reaction yield, and desired residue profile in the final agent.

    Downstream process integration

    • Introduced after functional group activation during core heterocycle formation; final intermediates are purified via liquid–liquid extraction and chromatographic separation before active ingredient formulation.

    Final product types

    • Active ingredient intermediates for naphthol-based fungicides
    • Technical-grade active compounds for granule and liquid concentrate pesticides
    • Preformulated dispersible granules
    • EC (emulsifiable concentrate) agrochemical premixes
    Free Quote

    Competitive 6-Methoxy-2-Naphthol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    6-Methoxy-2-Naphthol: Practical Insights from Our Production Floor

    Understanding 6-Methoxy-2-Naphthol—From Raw Material to Real-World Impact

    Making 6-Methoxy-2-Naphthol is a hands-on business. Our days revolve around this powdered phenolic derivative—keeping purity levels high, color consistent, flow smooth, and moisture down. It’s a core material with a chemical structure built on the naphthol backbone, specifically with a methoxy group at position six. After a couple decades in the lab and warehouse, the merits of this compound go far beyond its chemical formula. On production days, we see firsthand the demands that specialty dye houses, pharmaceutical labs, and some agrochemical formulators bring to our door. In each batch, trace contaminants must be eliminated. Discoloration or off-odors are early signs to halt the line.

    Product Identity and Model

    Our batches of 6-Methoxy-2-Naphthol carry a standard grade aligned with direct-use requirements in synthesis plants. Most output comes as a fine, off-white to light tan powder. Crystallinity, particle size, and odor—each is monitored across lots. We measure melting points and inspect for optical purity for applications that require it. In quality labs, spectroscopic analysis assures NMR peaks remain on target, supporting feedback from our biggest users. If the lab flags any deviation, that batch never leaves the facility.

    Years ago, we moved to glass-lined reactors for reliability. Temperature control must stay tight around reaction points, with skilled operators constantly tuning reflux, gas flow, and pressure. Downtime from equipment vulnerability leads to waste and customer delays. When the environment pushes humidity too high, operators cover every surface—this compound attracts moisture, which promotes clumping and loss of handling ease. Surfaces, scoops, lines—no shortcuts allowed.

    End-Use Applications: From Our Loading Dock to Industry Workbenches

    This naphthol derivative shows up as a molecular cornerstone in several demanding settings. Dye synthesis claims the bulk of our output, as it’s one of the few phenolic intermediates that delivers reliable color stability. Dye formulators tell us shifting molecular weight, trace copper, and off-odors send entire bleeding batches to waste. In years spent troubleshooting, a high-purity 6-Methoxy-2-Naphthol spikes repeatability in diazotization and coupling. Many of the most vibrant chromophores in textiles or digital print media bank on this raw material for batch-to-batch reproducibility.

    Pharmaceutical researchers reach out when medicinal scaffolds demand a naphthalene core with a degree of substitution untouched by the larger bulk intermediates. Small differences in alkylation, methylation, or residual water content influence downstream crystallization and separation. Many early-stage pharma innovators use our output for custom synthesis or process validation. Their teams report low levels of starting impurities reduce HPLC complexity down the line, cutting troubleshooting times.

    Specialty coatings and pigment producers report added value when using controlled lots of 6-Methoxy-2-Naphthol. Its role as a modifier in pigment nucleation platforms translates into more consistent opacity, gloss, and shelf-life in paints, inks, and plastics. In each of these end-markets, we hear the same refrain: one off-batch of raw material disrupts multiple formulations before the root cause shows up.

    Quality is a Day-to-Day Practice, Not a Marketing Slogan

    Manufacturing chemicals for years brings home an old truth: nothing replaces real-world vigilance. Our technical staff review every data point in the QC logs—there’s always a story in the data about what’s right and where things can slip. Raw material suppliers sometimes deliver feedstock showing minor solvent carryover, so intake screening matters. Line operators manually inspect and weigh weekly inventory—precision at every step limits mix-ups and rogue particulates.

    The end-users give us the learning curve. Several found early cost savings buying generic 6-Methoxy-2-Naphthol elsewhere, only to run into variabilities in melting behavior, sticking, or off-odors. The downtime they face for reformulation or tank cleaning costs several times more than an upfront investment in reliable output. R&D chemists in large programs call for direct communication between manufacturing teams; they want actionable data, full sample histories, and lot certification grounded in real process conditions, not just a data sheet.

    Key Distinctions from Other Phenolic Intermediates

    Compared to other naphthol derivatives, 6-Methoxy-2-Naphthol serves a tighter segment: specialty dyes, modified amines, and high-value pharmaceuticals. Compounds like 1-Naphthol or 2-Naphthol show broader commodity use but struggle in applications where methoxy substitution improves solubility, lowers oxidative instability, or changes color response under light. In pigment synthesis, the structure’s unique resonance effects lead to improved brightness and stability, essential for next-generation plastics and coatings.

    Many phenolic intermediates offer high throughput at lower cost, but they come with higher impurity content or less-selective substitution patterns. Some buyers only discover this at the application stage: inferior batch-to-batch consistency creates headaches. Our output never adopts a one-size-fits-all template. Heavy investment in trace analysis and contaminant management doesn’t just tick a quality box—it shields our customers from root-cause failures months later.

    Typical Specifications and Real-World Production Limits

    Our technical sheets outline expected purity (minimum 99 percent), residual moisture levels, and heavy metal maxima. Every shift, reality in the plant demands compromise—minor drops in purity happen under heat stress, or when feedstock runs hot from outside storage. Dry rooms and sealed storage prevent water pickup, but it requires day-to-day vigilance. Unlike automated bulk chemical lines, these specialty naphthols respond to small production shifts. Operators learn to spot and correct these shifts before data shows up on a printout.

    Packing and shipping also set limits. 6-Methoxy-2-Naphthol is sensitive to direct sunlight, so we use double-walled drums lined with light-blocking film. Unexpected delays in customs or intermodal transfer threaten shelf life for some customers—especially in high humidity or tropical climates. Over years, it became clear that joint planning with customers about real supply chains avoids these headaches. We keep buffer stocks and offer lot-specific release reports on request.

    Feedback from the Field: Customers Shape the Product

    Most improvements in our process trace back to the voices of industry users. Textile labs in northern Europe pushed for a tighter particle size spec to enhance their color yields, reporting that dustier lots from other manufacturers clogged filters and slowed their line rate. We retooled our sieving for tighter cuts, swapping out mesh and adopting anti-static handling. In pharma, a customer identified a subtle odor deviation—turned out our drum liner was interacting after a change in the resin source. Listening closely and correcting upstream spared both sides wasted time and failed runs.

    Across several countries, different users write in about solubility and powder flow. Dyestuff makers favored finer, nearly microcrystalline cuts; plastics specialists required more granular flow to avoid blockages. Bulk handling and conveying properties led us to introduce surface treatment options. Storage stability, especially in subtropical conditions, improved after routine feedback led us to test new antioxidant packing aids.

    Safe Handling and Environmental Management—Lessons Learned Over Years of Practice

    Real hazards emerge over time, not out of a specification sheet. Processing and packing rooms require excellent ventilation, as even trace dust irritates airways. Experienced team members take time over drum sealing, ensuring no leaks or residue remain. Over the years, we implemented closed-loop dust collection. Scrubbing air outflows reduced trace emissions and airborne load. Operators now work with improved PPE, after baseline exposure tests several years ago showed small but measurable upticks after prolonged exposure.

    Regulatory shifts have shaped our choices too. Several years back, rising restrictions on VOC emissions and waste water discharge demanded upgrades in solvent recovery. We tightened distillation controls and swapped out legacy solvents. Zero-discharge policies in key jurisdictions pushed toward near-total recycle of off-spec batch residues. Every plant visit from a safety consultant brings a new perspective—often, their observations point out blind spots our daily routines miss.

    Comparing to Sibling Compounds: Why 6-Methoxy-2-Naphthol Wins Its Place

    Among related naphthol compounds, only 6-Methoxy-2-Naphthol combines a methoxy group that alters electron density, so downstream synthesis produces vivid, stable dyes and tailored intermediates. Bulk 1- and 2-Naphthol, standard in older dye facilities, lack this substitution and cannot match either hue control or finished product durability. In pharma, the differentiated scaffold opens more avenues for QSAR exploration, which matters for lead optimization and patent strategies.

    Every year, chemists bring us new custom requests—tuning optical purity, shifting melting point for easier downstream blends, even maximizing chiral purity for advanced synthons. Most requests require tweaks to temperature management or solvent rate, not full process redesigns. In each case, detailed process notes—the kind only available from firsthand manufacturing logs, not generic supply—speed up troubleshooting.

    Process Transparency Builds Partner Confidence

    Customers demand not just high-quality compound but explicit process evidence. Every technical query about trace metals, odor, or packing material traces directly to batch records and archived test runs. Audits never surprise our crew; logs and retained samples remain available for real track-and-trace checks. Trust grows from open feedback and direct data access between engineers, not from generic certificates.

    Supply interruptions or unexpected deviations cost everyone. Users expect immediate confirmation of lot status. We keep samples of every batch, and often, when a new synthesis fails, the customer’s lab contacts us directly, looking for underlying root causes—things like unexpected microcontaminants, temperature excursions, or nonstandard packing. By offering transparency into our own test results and process interventions, we reduce finger-pointing and wasted effort for everyone.

    Commitment to Reliable Supply in a Volatile Market

    Precision specialty chemicals often suffer from supply chain shocks: feedstock price surges, port closures, regulatory “surprises.” To operate smoothly, advance planning matters more than cost-cutting. Over years, we established multiple supplier relationships for upstream materials, sometimes holding extra finished product at cost just to spare customers sudden interruptions. Larger projects schedule deliveries months in advance, but small R&D teams may call in new orders at a moment’s notice. Rapid turn-around requires flexibility: we built that into our shift planning and small-batch segregation.

    Every disruption points back to process resilience. Flooded delivery routes or weather delays put a freeze on outbound lots, so alternative routing protocols went into effect. We never ship without batch release testing or environmental condition checklists. That discipline means customers rarely see a late delivery or degraded lot.

    Environmental Responsibility Extends Beyond the Plant Gate

    Communities around our sites pay close attention to our practices. Odorous or accidental dust releases show up in local reports fast. Over the last decade, outreach assemblies and transparent reporting built relationships; citizens know who to call at the plant for real-time information. Internal audits follow stricter-than-required local environmental guidelines. We invest in process water reclamation systems—both to remain compliant and to honor the trust neighbors have placed in us.

    Some customers highlight this in their own auditing: major brands, especially in textiles and electronics, screen their suppliers for actual EHS implementation. Our process upgrades sustain those claims in contract bids and keep doors open to global partnership.

    Future Directions: Keeping Pace with Industry Demand

    New uses for 6-Methoxy-2-Naphthol emerge as chemical innovation accelerates. Upstream intermediates for OLED displays, high-durability inks, and specialty pharma actives draw on the reliability of our product. As users push for even stricter specs—lower heavy metal content, improved environmental footprint, better custom packaging—we adapt. Our R&D team works closely with customers, running trials with alternate feedstocks and greener process reagents.

    Longstanding customers look for continuous improvement, not just basic compliance. We track every global trend: non-phthalate plastics, reduced solvent loads, single-use plastic recycling commitments. These market changes shape both product design and downstream service choices. By engaging directly with R&D groups—not just procurement offices—we keep up with novel formulation puzzles and regulatory shifts.

    Conclusion Is Written on the Shop Floor

    No synthetic intermediate stands alone, and every kilo delivered links directly to the hands that made it. For 6-Methoxy-2-Naphthol, that means consistent vigilance over quality, self-scrutiny over process integrity, and a willingness to respond to real customer challenges. Down-to-earth reliability keeps our output a preferred choice, batch after batch, year after year. Every feedback loop becomes a chance to learn; every production obstacle, an opportunity to refine and improve. From the plant floor to the end-user bench, this approach earns us a seat at the table in specialty chemicals.