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6-Amino-2-Naphthalenesulfonic Acid

    • Product Name 6-Amino-2-Naphthalenesulfonic Acid
    • Alias 6A2NS
    • Einecs 202-080-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    578956

    Product Name 6-Amino-2-Naphthalenesulfonic Acid
    Cas Number 90-13-1
    Molecular Formula C10H9NO3S
    Molecular Weight 223.25
    Appearance Light brown to beige powder
    Melting Point 300 °C (decomposes)
    Solubility In Water Soluble
    Density 1.52 g/cm3
    Ph Of 1 Solution Approximately 3.5
    Synonyms 6-Amino-2-naphthalenesulfonic acid; Tobias acid
    Ec Number 201-973-7
    Pubchem Cid 70014

    As an accredited 6-Amino-2-Naphthalenesulfonic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 6-Amino-2-Naphthalenesulfonic Acid is packaged in a sealed 100-gram amber glass bottle with a secure screw cap.
    Shipping 6-Amino-2-Naphthalenesulfonic Acid is shipped in tightly sealed containers, protected from moisture and light, and labeled according to relevant regulations. It is transported as a chemical substance under standard, non-hazardous conditions. Ensure proper packaging and documentation, handling with care to avoid spills or contamination during transit. Store in a cool, dry place.
    Storage **6-Amino-2-Naphthalenesulfonic Acid** should be stored in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers. Protect it from moisture and direct sunlight. Recommended storage temperature is room temperature (20–25°C). Use chemical-resistant shelving and clearly label the container. Always follow local regulations and safety guidelines for chemical storage.
    Application of 6-Amino-2-Naphthalenesulfonic Acid

    Applications of 6-Amino-2-Naphthalenesulfonic Acid in Industrial Manufacturing

    6-Amino-2-naphthalenesulfonic acid (6-ANS) is widely recognized as a foundational intermediate in the chemical industry, especially in colorant and dye synthesis. Our direct production and quality control ensure reliable raw material input for numerous downstream operations. The following application scenarios illustrate actual industrial uses, with details on industry standards, formulation ratios, process integration, and the final manufactured goods.

    1. Azo Dye Manufacturing for Textiles

    6-ANS acts as an essential coupling component in the synthesis of direct, acid, and reactive dyes for cellulosic and protein fibers. Textile dye manufacturers select this intermediate for creating vivid and stable colorants, particularly reds and oranges, optimizing shade strength and washfastness. Its utilization directly influences color yield, migration resistance, and bond strength on cotton, wool, and blended fabrics.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (tested for harmful substances)
    • ZDHC MRSL v3.1 (Zero Discharge of Hazardous Chemicals)
    • REACH Regulation (EC) No 1907/2006
    • ISO 105 series (Color fastness testing for textiles)

    Typical usage ratio

    • 15–40% of total diazo component by weight, depending on chromophore requirements; adjusted according to targeted shade intensity and desired fastness properties.

    Downstream process integration

    • Integrated into azo dye synthesis at the coupling stage, following diazotization of aromatic amines; dye slurry is then filtered, spray-dried, or salted out for further formulation.

    Final product types

    • Direct dyes for cotton textiles
    • Acid dyes for wool and polyamide fibers
    • Reactive dyes for cellulosic blends
    • Printed and yarn-dyed fabrics

    2. Pigment Intermediate for High-Performance Industrial Coatings

    Within pigment synthesis, 6-ANS acts as a precursor for complex organic pigments featuring high light and solvent fastness. It supports the formation of mono- and disazo pigments used in automotive and industrial paints where stringent exterior durability is needed. Coating manufacturers value this feedstock for tuning pigment crystal habit and consistency.

    Industry compliance standards

    • EN 71-3:2019 (Safety of toys – migration of heavy metals in coatings)
    • US EPA TSCA Chemical Inventory
    • ISO 12944-6 (Paints and varnishes — Corrosion protection of steel structures)
    • Automotive OEM internal pigment migration protocols

    Typical usage ratio

    • 18–30% of total pigment intermediate load; the proportion is determined by chromophore design and required opacity.

    Downstream process integration

    • Introduced during the coupling or condensation step of pigment synthesis, enabling further processing—filter cake is purified, milled, and dispersed for paint or powder applications.

    Final product types

    • Automotive refinishing paints
    • Industrial powder coatings
    • Protective marine or infrastructure coatings
    • High-durability architectural paints

    3. Intermediate for Food Contact Colorants

    Food and beverage packaging colorant producers use 6-ANS as a controlled aromatic amine source in certain colorants for inks and coatings intended for indirect food contact. Strict monitoring supports compliance in colorant migration and heavy metal regulations, especially in regions such as the EU and US. Manufacturers depend on this raw material’s purity profile to meet downstream food safety audits.

    Industry compliance standards

    • EU Regulation 10/2011 (Plastics materials and articles intended to come into contact with food)
    • FDA 21 CFR Part 175.300 (Resinous and polymeric coatings)
    • Swiss Ordinance on Materials and Articles in Contact with Food (SR 817.023.21)
    • Good Manufacturing Practice Regulation (EC) No 2023/2006

    Typical usage ratio

    • 0.5–6% in colorant formulation for food packaging coatings or inks; adjusted for end-use migration limits and regulatory thresholds.

    Downstream process integration

    • Enters as an intermediate during the synthesis of food packaging-eligible pigments or direct dyes; further purified and incorporated into compliant ink or lacquer formulations.

    Final product types

    • Printing inks for beverage cans and food wrappers
    • Colored lacquers for food container linings
    • Secondary coatings for food-grade plastics
    • Label inks for direct or indirect food contact

    4. Raw Material for Pharmaceutical Intermediates

    Pharmaceutical synthesis sometimes utilizes 6-ANS as a building block for producing active pharmaceutical ingredient (API) intermediates, especially those containing sulfonated naphthyl structures. API manufacturers rely on traceable material and high lot-to-lot consistency to support route scouting and final synthesis of specific antihypertensive and antihistamine agents.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • European Pharmacopoeia (Ph. Eur.) monographs where applicable
    • US FDA cGMP Guidelines (21 CFR Parts 210 & 211)
    • USP–NF compendial guidance for relevant APIs

    Typical usage ratio

    • Applied as a stoichiometric intermediate in multi-step synthesis; concentration controlled for each batch based on theoretical molar calculation—commonly 1.0–1.15 equivalents for key coupling reactions.

    Downstream process integration

    • Introduced at the designated condensation, substitution, or coupling reaction step; intermediate is then purified by crystallization, extraction, or distillation for final API preparation.

    Final product types

    • API intermediates for certain antihypertensive agents
    • Precursor for naphthalenesulfonic-based antihistamines
    • Sulfonic acid derivatives for custom contract synthesis
    • Pharmaceuticals using sulfonic modification for increased solubility

    5. Intermediate in Paper Dyeing and Paper Chemicals

    Paper dye manufacturers incorporate 6-ANS as a sulfonated aromatic coupling component for formulating direct and basic dyes, yielding high-affinity colorants for uncoated paper, tissue, napkins, and packaging grades. Its utilization enables high brightness levels, anti-fading characteristics, and resistance to migration under wetting conditions in paper products.

    Industry compliance standards

    • EN 646 (Determination of colour fastness of dyed paper and board)
    • EU REACH Regulation (Annex XVII for azo dye restriction)
    • KBA List for printability and food suitability
    • ISO 187 (Physical testing for paper and board)

    Typical usage ratio

    • 12–27% in dye-forming reactions; adjusted for depth of tone and brightness of the end-use paper product, monitored by optical density testing.

    Downstream process integration

    • Added as a coupling component during dye synthesis; resultant dye is processed through ultrafiltration and microdispersion for even distribution in paper finishing or wet-end application.

    Final product types

    • Colored tissue and hygiene paper
    • Decorative and packaging papers
    • Stationery and print-grade paper
    • Water-resistant colored labels and wrappers
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    Certification & Compliance
    More Introduction

    6-Amino-2-Naphthalenesulfonic Acid: Reliability from the Source

    Direct from the Manufacturer—Experience at Every Step

    In chemical manufacturing, we know trust doesn't come out of thin air. Our years of hands-on experience tell us this: a well-made 6-Amino-2-naphthalenesulfonic acid goes far beyond what the formula shows on paper. Every batch rolling out of our plant reflects habits learned from decades in the shop—watching temperature, checking purity, and listening when customers tell us what works on their end and what doesn’t.

    We produce this compound, also known simply as 6A2NSA by folks who work with it a lot, as a crystalline powder. It’s got a white to off-white color when it’s made right, but anyone who’s ever dealt with low-grade stock has seen how quickly the hue can slide to brown or yellow if impurities creep in. There’s more to this than looks: that color shift almost always means the underlying structure got compromised somewhere between reduction and sulfonation, and that changes how it behaves down the line. Over the years, we took apart failed syntheses from other factories, ran breakdowns on degraded samples, and figured out where things go sideways. That’s how we settled on our standard—no batch heads to packing until sharp eyes and solid equipment say it measures up.

    Why 6-Amino-2-Naphthalenesulfonic Acid Matters

    It shines brightest as an intermediate for azo dyes. Dyes made from our 6A2NSA stand out in textile runs, because they resist washing out and keep their shade under light, heat, or sweat. Our customers in pigment manufacturing want that, and the reason is simple: once a dye fails in field use, nobody remembers who made the shirt—they just remember the color ran. Our job is to produce an ingredient that never causes that problem. Chemical workers in our plant understand how small changes in starting material ripple through to the finished dye, and this compound is a textbook case. It’s not a “one size fits all” intermediate; some textile makers need a tighter melting point range or lower sulfonic acid content for specific chromophore syntheses. We don’t set those specs behind a desk—we test, reformulate, and adjust based on what end users need to get their products through QC without hiccups.

    The paper and leather industries have also come to rely on precisely made 6A2NSA. In the world of paper, certain grades require dye precursors that avoid feathering or bleed. Our sulfonic acid group location helps with this, giving dyes a real edge in sharpness and staying power because the acid sits at the naphthalene ring’s second point. Leather finishers tell us traditional dyes slump or break down in acidic chrome tanning baths—our compound stands up to it, making lasting shades possible.

    Form and Handling—Why Every Detail Counts

    We run this product as a fine crystalline powder to avoid clumping in storage and shipping. Some manufacturers send out larger granules or pressed forms, but in our experience, those give inconsistent dissolution in aqueous dye baths or finishers’ solutions. We go through extra milling and sift through screens to check for even particle size. Unmilled bulk powders cause headaches at the factory: blobs that don’t dissolve mean wasted product and off-shade batches down the pipeline.

    Moisture is another sore spot in this chemical. 6A2NSA is hygroscopic, but you wouldn’t know it unless you’ve had to scrape a sticky, clumpy mess from a drum in monsoon season. We invested in humidity control and high-barrier packaging for a reason. Some buyers ask us to leave the product “as is,” but the ones who’ve run up against lumped material soon start requesting our packed drums with desiccants. Packing under dry nitrogen isn’t just a point on the checklist—it’s how we help our customers avoid hours spent hammering at solidified powder instead of making colorants.

    Purity and Process: Lessons Learned on the Production Line

    Purity isn’t a marketing term for us—it’s what shapes every step from reaction vessel to storage tank. Trace organics, leftover metal catalysts, and unconverted sulfonic compounds show up in finished product quality. Old-school makers sometimes cut corners, selling on price with lower assay material. You can spot these batches: UV spectra look off, dye reactions hang up, and customers get stuck troubleshooting instead of producing.

    From our first pilot runs, it was obvious that control makes or breaks this product. Our technicians still remember what happens when sulfonation runs too hot—blackened product, acidic stench, ruined batch. We tweaked our process step by step, controlling temperature ramps with more precision, using high-purity sodium nitrite for diazotization. We patch up bottlenecks fast by keeping our chemists, maintenance team, and QC folks on the same page, not in separate silos. Factory veterans warn newcomers: “Don’t trust a process just because it ran fine last month.” Washing and drying protocols changed over the years, too: overdrying bakes the powder into hard lumps, skipping a wash leaves back-end traces that spoil dye chromaticity. Even trace iron residues from pipework can muddy a batch’s color output; so we swapped out some lines to do better.

    A lot of suppliers ship with assay between 98–99% by HPLC. We aim for the high end, since the last few decimal points cut way down on waste and side reactions in dye coupling. Customers running high-throughput production lines see the difference—less gunk, more yield. Early on, we realized analytical chemists working for dye plants always test raw materials on arrival; once they see solid numbers from us, they stick around for the next cycle.

    Comparing with Other Naphthalenesulfonic Acids—What Sets Ours Apart?

    The naphthalene ring system allows lots of possible substitutions—each creates a new compound with a unique role in the dye world. 6-Amino-2-naphthalenesulfonic acid differs from its positional isomers. Move the amino or sulfonic group to another position and solubility, reactivity, and the color properties in the finished dye all shift. Some makers lump everything together; in our plant, our technicians track each isomer to make sure no cross-contamination creeps into the process.

    Results tell the real story. In side-by-side dye syntheses, 6A2NSA produces spectral profiles and colorfastness different from, say, 4-amino-1-naphthalenesulfonic acid. Factories attempting to swap one for the other learn quickly that color output drifts toward murky or faded shades, not the crisp, stable tones they expect. Over time we developed QS procedures to root out even trace cross-contamination in shared lines. No manufacturer trusts a line that gets “cleaned up between runs” without regular, thick-check sampling. We spend money on these steps because we’ve witnessed both the cost, and the reputation loss, of batches rejected for stray isomer traces.

    We also notice that end users in different industries look for specific isomers based on their process designs. Some dye houses insist on 6A2NSA specifically because it has an excellent record for building direct and acid dyes with high water solubility. Others want related compounds to create disperse dyes for synthetics. We make it a point not to substitute or blend, because swap-outs usually lead to call-backs and claims. Consistency saves everyone time and money and keeps relationships honest.

    Usage Insights—Lessons Passed Down the Line

    Customers typically use this material midstream, either coupling it with diazonium salts in aqueous solution or as a foundation for building more complex dye molecules. We sometimes field calls from new clients asking about optimal solvent ratios or reaction conditions. We tell them what works here in our own test labs, and we don’t keep those tweaks and tips to ourselves.

    Heating too rapidly or choosing low-grade buffers often introduces byproducts—azoxy or tarry residues that kill color strength. Years ago, we paired up with textile partners to run controlled trials, so today we can recommend buffer systems and pH ranges with confidence. It sounds simple, but even tweaks to stirring speed or cooling rates in the plant mean the difference between high-yield coupling and scrap batches of weak chromophores. Those lessons show up in our technical notes, not just our marketing.

    Pharmaceutical interests sometimes ask about using 6A2NSA as an intermediate. We respond by sharing spectral data and impurity profiles, but we always remind those customers that trace impurities matter a lot more in pharma than in dyeing. Our material matches what dye and colorant industries require, but we advise anyone aiming for APIs or regulated substances to run extra purification or certified trace metals analysis.

    Our experience makes it clear that the best results come from thinking ahead. Keeping the compound dry, handling it with minimal exposure to air, and keeping reaction vessels clean all matter. Chemists who rush through prep or ignore small clumps of unknowns in the feedstock usually learn the hard way—off-spec dyes, costly downtime, or worse, a whole run thrown out.

    Troubleshooting with a Manufacturer’s Perspective

    Even high-purity batches can run into headaches at the user’s end if storage or handling breaks down. Over the years, we spent time at customer sites to see how products performed out in the field. Sometimes, we saw broken seals, drums left open too long, or powders sitting outside in humid weather. People sometimes looked for ways to cut corners to save a few bucks, only to wind up spending more cleaning out sticky machinery or scrapping a whole dye run due to caking or contamination.

    We realized early on that a manufacturer’s job doesn’t end at the factory gate; it stretches all the way through to the customer’s application. That’s why we share practical storage advice and encourage clients to call us if they run into trouble. On one job, a customer’s dye batches started coming out too dull. They thought maybe the formula changed, but after a site visit, we saw their splitters had started storing the product unpackaged in an unconditioned warehouse. Moisture pickup explained the change in results. By sharing proven handling and storage methods—like airtight containers and regular turnover of stock—we help customers squeeze value from every kilo.

    Occasionally, buyers try sourcing cheaper material from traders or poorly vetted plants. They may not see problems in a simple melt-point check, but over time, substandard feeds take their toll—clogged filters, variable yields, or out-of-spec product shipped to end users. We’ve seen companies chase short-term savings only to rack up higher costs from troubleshooting runaway side reactions or cleaning up contaminated systems. Our focus remains on delivering a product that’s going to work, batch after batch.

    Improvements in Production and Customer Support

    Our years in this industry taught us that you can’t stand still. Process improvements mean more than chasing volume or speed; every shift in upstream commodity cost, every environmental regulation, and every new analytic tool on the market has something to teach. For 6A2NSA, we constantly refine our approach—switching to greener sulfonation agents, tightening emission controls, and connecting with suppliers who prove their reliability.

    We keep a close eye on trace element profiles, because many textile and paper makers operate in regions with stiff environmental oversight. We switched to recycled water for rinsing and added upgraded scrubber systems in our plant, cutting down on sulfur emissions and demonstrating both compliance and commitment to cleaner operations. Some new customers come to us for this reason alone: they’ve received warnings about wastewater or atmospheric discharges from using lower-tier feedstock supplied by cut-rate outfits. We share our environmental data openly—not because it’s expected, but because we want manufacturers downstream to see that risk is being managed well before their workers ever open a drum.

    Through all of this, we learned it’s not enough to deliver a drum and walk away. Over time, we built teams who know how to troubleshoot, respond to technical queries, and help partners learn more about the product they rely on every day. We get a steady stream of calls asking about compatibility with new process upgrades or alternative solvents; our staff stays trained and up to date, so we offer useful advice, not just boilerplate warnings.

    Technical documentation is only as good as the trust it’s built on. We curate SDS and COA documents based on real analytic results, not wishful thinking. Buyers face enough friction from shifting supplier claims—in this plant, everyone signs off on what leaves the production floor. Whenever a customer sends back a report or an analysis that questions our data, it gets escalated for review. We learn more from these moments than from all the “good job” feedback in the world. Every mistake is a lesson. Years ago, a missed metal trace led us to overhaul our cleaning protocols and swap suppliers for critical reagents. Now, we run more checks, not fewer, and we’re not shy about sharing these updates with customers.

    What We’ve Learned by Listening to End Users

    Our company started small, but over time, many relationships with customers grew from a single order into years of back-and-forth—sharing successes, working through setbacks. In the case of 6A2NSA, real improvements always came from the ground up: factory techs, production planners, QC chemists, and even logistics teams giving honest feedback. Those conversations shaped how we handle packing and shipment, what test reports we generate, and how we adjust for seasonal swings in temperature or humidity.

    We’ve seen the market shift from bulk buyers focused only on unit price to a new type of customer, one who cares about broader impacts: traceability, environmental safety, risk reduction. The companies that return year after year usually aren’t the ones chasing the lowest bidder—more often, they’re firms looking for a partner who stands ready to solve problems, not just drop off a pallet. We work directly with procurement teams to forecast demand, schedule deliveries, and plan for possible disruptions. Long-term supply chain reliability proves just as valuable as color strength or particle size.

    There’s pride in knowing our 6A2NSA finds its way into fabrics, papers, leathers, and other materials used around the world. We don’t see ourselves as just a factory plugging in a standard product code. To our crew, this compound is a link in a long chain stretching from petroleum to laboratory, reactor vessel to finished shirt or book cover. Each step taken with care, each batch checked and rechecked, each drum shipped with an eye on consistency and honesty.

    We take it as a badge of honor when customers send us photos of finished goods, sealed dye lots, or new product launches, telling us that what started in our reactors finished strong on store shelves. We encourage our partners to keep sharing those insights and challenges—that’s where the next round of improvements comes from, and that’s how real trust gets built in the chemical industry.

    Looking Ahead—Responsibility and Innovation

    Chemical manufacturing grows more challenging with every passing year. Pressures from regulators, environmental requirements, raw material volatility, and customer demand all move at a fast clip. Our answer is to lean on what we know: taking care in each step, telling it like it is, and always looking for tweaks and advances that genuinely help our customers.

    For 6-Amino-2-naphthalenesulfonic acid, we’ll keep searching for cleaner practices, better quality controls, and technical advances that suit real-world needs. Our lines remain open for questions, support, and feedback. To those who choose to work with us, you can expect openness, hard-won expertise, and products that help you succeed in whatever industry you serve.

    Batches come and go, product codes may shift, but the habits and lessons built over a career in production keep shaping every decision we make. 6A2NSA may look to some like just another chemical powder—behind every drum, there’s a plant team proud of their work, a promise to do right by the customer, and a drive to keep doing it better next time.