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6-(2,2,2-Trifluoroethoxy)Nicotinic Acid

    • Product Name 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid
    • Alias 6-TFENA
    • Einecs 629-004-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    880127

    Product Name 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid
    Cas Number 132062-14-5
    Molecular Formula C8H6F3NO3
    Molecular Weight 221.13 g/mol
    Appearance White to off-white solid
    Purity Typically ≥ 98%
    Melting Point 130-134°C
    Boiling Point No data available
    Solubility Slightly soluble in water; soluble in DMSO and methanol
    Storage Conditions Store at 2-8°C, protected from light and moisture
    Smiles C1=CC(=NC=C1C(=O)O)OCC(F)(F)F
    Inchi InChI=1S/C8H6F3NO3/c9-8(10,11)4-15-6-2-1-5(7(13)14)12-3-6/h1-3H,4H2,(H,13,14)
    Refractive Index No data available
    Synonyms 6-(Trifluoroethoxy)nicotinic acid

    As an accredited 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 10 grams of 6-(2,2,2-Trifluoroethoxy)nicotinic acid, securely sealed with a screw cap, labeled clearly.
    Shipping 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid is shipped in tightly sealed containers to prevent moisture and air exposure. It is packaged according to standard regulations for chemicals, often with cushioning materials for protection during transit. Appropriate hazard labeling and documentation are included to ensure safe and compliant transport. Store in cool, dry conditions.
    Storage **6-(2,2,2-Trifluoroethoxy)nicotinic acid** should be stored in a tightly sealed container, kept in a cool, dry, and well-ventilated area away from direct sunlight and sources of ignition. Store at room temperature and avoid moisture. Ensure it is kept away from incompatible substances such as strong oxidizers. Use personal protective equipment when handling to prevent skin and eye contact.
    Application of 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid

    Purity 98%: 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid with 98% purity is used in pharmaceutical intermediate synthesis, where high chemical purity ensures optimal yield and minimal byproduct formation.

    Melting Point 135°C: 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid with a melting point of 135°C is used in solid-state drug formulation, where thermal stability supports uniform tablet processing.

    Molecular Weight 221.15 g/mol: 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid at 221.15 g/mol is used in medicinal chemistry screening, where defined molecular mass assists in accurate compound dosing.

    Particle Size D90<10 μm: 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid with D90 particle size below 10 μm is used in inhalation formulation, where fine particle distribution enhances pulmonary absorption efficiency.

    Stability Temperature 60°C: 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid stable up to 60°C is used in controlled-release applications, where thermal resilience maintains compound integrity during processing.

    Water Content <0.5%: 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid with water content below 0.5% is used in moisture-sensitive drug development, where low hygroscopicity prevents degradation and extends shelf life.

    Assay ≥99%: 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid with assay not less than 99% is used in high-throughput biological evaluation, where assay accuracy ensures reproducible pharmacological data.

    Residual Solvent <0.1%: 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid with residual solvent below 0.1% is used in GMP-compliant manufacturing, where controlled impurities meet regulatory standards.

    LogP 1.8: 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid with LogP of 1.8 is used in drug solubility optimization studies, where balanced lipophilicity supports enhanced bioavailability.

    UV Absorbance 260 nm: 6-(2,2,2-Trifluoroethoxy)Nicotinic Acid with UV absorbance at 260 nm is used in analytical method development, where distinctive absorbance enables rapid quantification.

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