|
HS Code |
543853 |
| Chemical Name | 5-Methoxy-2-Nitrobenzoic Acid |
| Cas Number | 16622-45-0 |
| Molecular Formula | C8H7NO5 |
| Molecular Weight | 197.15 |
| Appearance | Off-white to yellow solid |
| Melting Point | 154-158°C |
| Solubility | Slightly soluble in water, soluble in organic solvents |
| Pubchem Cid | 3075849 |
| Smiles | COC1=CC(C(=O)O)=C([N+](=O)[O-])C=C1 |
| Inchi | InChI=1S/C8H7NO5/c1-14-6-3-2-5(8(10)11)7(4-6)9(12)13/h2-4H,1H3,(H,10,11) |
| Storage Conditions | Store in a cool, dry place |
As an accredited 5-Methoxy-2-Nitrobenzoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 100g amber glass bottle labeled "5-Methoxy-2-Nitrobenzoic Acid," featuring hazard symbols, product details, and lot number. |
| Shipping | 5-Methoxy-2-Nitrobenzoic Acid is shipped in secure, sealed containers, protected from moisture and light. It is packaged and labeled in compliance with regulatory standards for hazardous chemicals. Appropriate documentation accompanies the shipment, and handling instructions ensure safety during transport. Keep upright and store at controlled room temperature upon receipt. |
| Storage | 5-Methoxy-2-nitrobenzoic acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area. Protect it from moisture, direct sunlight, and sources of ignition. Store away from incompatible substances such as strong oxidizers and reducing agents. Ensure proper labeling and keep the container in a designated chemical storage area, following all relevant safety guidelines. |
Applications of 5-Methoxy-2-Nitrobenzoic Acid in Industrial ManufacturingWith an established footprint in advanced organic synthesis, 5-Methoxy-2-Nitrobenzoic Acid provides recognized performance in select chemical product sectors where controlled reactivity and purity are mission-critical. Below, we outline verified downstream application scenarios, focusing on precision formulation, industry-specific controls, and direct process integration based on real-world manufacturing systems. 1. Pharmaceutical Intermediate for Anti-inflammatory AgentsPharmaceutical manufacturers incorporate 5-Methoxy-2-Nitrobenzoic Acid as a building block for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), notably during the construction of substituted benzoic acid derivatives. This material supports targeted structural modifications required for active pharmaceutical ingredient (API) development in regulated production lines, where consistency of functional group introduction is essential for achieving the desired pharmacodynamic profiles in finished drug products. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Agrochemical Synthesis — Herbicide IntermediateAgrochemical producers use this compound as a precursor in the assembly of selective herbicide molecules, specifically within the benzoic acid family applied to row crop and plantation markets. High regioselectivity during downstream derivatization helps ensure product effectiveness and crop safety, making trace-level purity and controlled reactivity critical in large-scale continuous production lines. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Dye & Pigment Intermediate — Azo Dye SynthesisThe dye industry deploys 5-Methoxy-2-Nitrobenzoic Acid in the preparation of custom azo dyes, where it serves as an electron-withdrawing substituted aromatic acid to drive color shade stability and solubility tuning. This application demands narrow batch-to-batch consistency, particularly as the intermediate participates in diazotization and coupling processes leading to colorant systems used in textile and specialty pigment applications. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Fine Chemical Intermediate — Synthesis of Specialty Aromatic CompoundsProducers of specialty aromatic compounds leverage this raw material for constructing advanced functional group architectures, particularly when developing halogen- and nitro-substituted benzoic derivatives targeted at high-value applications such as electronic chemical synthons, corrosion inhibitors, and advanced material co-monomers. Manufacturers depend on tight control of impurity levels and modular scale-up paths for pilot to full commercial quantities. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Photographic Chemical Synthesis — Coupler PrecursorIn the photographic chemical sector, this acid derivative features as a precursor for constructing image couplers used in specialized emulsion layers of silver halide films and photo-reactive printing systems. Strict compositional uniformity and reactivity predictability are necessary to guarantee image resolution, color sharpness, and layer adhesion throughout extended manufacturing campaign runs. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
|
Competitive 5-Methoxy-2-Nitrobenzoic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: admin@sinochem-nanjing.com
Flexible payment, competitive price, premium service - Inquire now!
Manufacturing chemicals is more than mixing and measuring. Every batch says something about the people behind it—those of us in the plant, those sampling, filtering, heating, and cooling day in and day out. This philosophy shapes our approach to making 5-methoxy-2-nitrobenzoic acid, a solid option for those looking to carry out specialized syntheses or fine-tune pharmaceuticals. We don’t just offer this product; we make it, relying on our teams' daily attention to detail to deliver exactly what chemists and manufacturers want for their next project.
5-methoxy-2-nitrobenzoic acid has found its way onto a variety of lab benches and into production lines, showing up frequently in pharmaceutical R&D, specialty chemical synthesis, and the development of agrochemical intermediates. On our end, we've worked hard to ensure each kilogram demonstrates the stability and chemical consistency that our customers count on when laying out their next process plan.
As a manufacturer, we sometimes hear questions about what sets our 5-methoxy-2-nitrobenzoic acid apart from similar benzoic acid derivatives. Reliability starts at the beginning. Unlike traders or middlemen who may move material between warehouses, we see our work from the inside out. Every raw material lot gets checked before hitting the reactors. Temperatures, reaction times, and air exposure all sit under the watchful eyes of our plant crew. This product is not bulk commodity acid—it comes off our line with a batch sheet attached and a lab report checked by people who know what to look for, because we've solved these quality headaches firsthand.
The official model number attached to our 5-methoxy-2-nitrobenzoic acid is tied to specific production settings and output purity. Each year, we comb through customer feedback, research findings, and our in-house stability data. We’ve learned that color and particle size frequently matter, especially for downstream uses in pharma and fine chemicals. So, granule size, melting range, and moisture content are kept within tight limits.
Our in-process checks pick up on the kind of subtle differences that make all the difference by the time the compound gets to the customer’s bench. Sharp melting point, precise methoxy substitution, consistent nitro group placement—these are checks we carry out, because in our experience, a small slip in structure ruins later results. Purities typically run above 99 percent, but more than just the numbers, it comes down to repeatability: We back each batch with a full analytical profile and keep samples on reserve, letting us track every lot back through the full production timeline.
Out on the production floor or in the applied research department, 5-methoxy-2-nitrobenzoic acid's appeal is real. In drug discovery labs, it provides a strong starting point for synthesizing more complex intermediates. Teams in these fields often remark on its compatibility with standard esterification and aminolysis protocols, reducing the time spent troubleshooting side reactions or impurities. Where other benzoic acid derivatives can introduce unwanted byproducts, the methoxy and nitro groups in this molecule tend to support more selective chemistry—a detail we've verified again and again during customer feedback cycles.
In agricultural chemical development, the molecule often finds use as a stepping stone for newer compounds, with our consistent batch profiles supporting tighter process controls downstream. Over the years, we've heard from formulators who rely on our product’s ability to maintain predictable reactivity under differing process temperatures and pressures. These observations don’t come from marketing materials; they come from technical teams that visit us, ask about our process controls, and troubleshoot real-world problems with our input.
Academic labs also frequently reach out to us when they need well-characterized starting materials for method development or regulatory studies. Our open-door policy means university partners have often visited to review our production logs themselves, because a trusted source of reference-grade material has become harder to come by amid shifting supply chains. We appreciate these exchanges, recognizing that collaboration with scientific users helps us continuously refine our process.
We keep a close eye on trends in the supply chain, and we hear customer frustrations over substitution and batch-to-batch inconsistency when buying from brokers or lesser-known sources. Our direct production process battles these issues by instituting traceability from raw input through packaging. Synthetic steps use controlled, modern catalysts and reagents, and purification follows current best practices, not just the fastest or cheapest method. This detail matters for receiving labs: A difference in trace impurities can cost hours—or days—of lost time during a development program.
As a company that owns the process and shoulders every audit responsibility, we pay attention not just to the final purity but to byproduct profiles, solvent residues, and even packaging choices. Lab managers and production planners want what they ordered, not a compromise. Over many years, we've learned to flag anything that looks unusual, and our teams keep a dialogue open with our biggest customers, gathering feedback on yield improvements, solvent swaps, or new downstream requirements. These conversations shape our continuous improvement cycles—for example, installing a new filter module after hearing about a customer’s trace particulate problems. This dedication is inherent to our process, not an ad-hoc adjustment.
It’s common to see 5-methoxy-2-nitrobenzoic acid appear in commercial catalogues. Some brokers repackage drums shipped in from overseas. The real difference lies in knowing the material’s origins. Our plant teams have invested in analytical methods specific to this compound. Infrared, HPLC, elemental analysis—all tailored to measure quality where it counts. We share this data with every shipment, not just to meet a spec sheet, but to pass our own standards. On several occasions, we’ve been able to work with partners to identify the source of reactivity drifts and trace it back to subtle changes in the upstream synthons or process solvents—a level of troubleshooting impossible without intimate process knowledge.
Another aspect that makes a difference is how we handle regulatory documentation. Medical and agricultural advances increasingly depend on well-documented starting materials. Our documentation package pulls from real-time production records, stability testing, and ongoing improvement projects. International customers especially depend on our ability to supply single-lot shipments and long-term batch archival, supporting audits and filings across multiple jurisdictions. We do this not as an afterthought, but because over the years, missing just one certificate or contaminant check can cause significant disruption to an entire research program.
Fine chemical production poses unique challenges that textbooks often overlook. Water content, variation in raw materials, even seasonal temperature shifts can affect yield and quality. We've built our process to handle these realities. For example, our team invested heavily in environmental controls, so that weather or supplier hiccups don’t influence the next day's output. Each improvement usually comes from solving a real problem—a failed recrystallization, a shipment delay, or an unexpected impurity during QC testing.
Waste reduction matters on both an economic and environmental level. Over the years, we've adopted solvent recovery, real-time process monitoring, and strict lot tracking. Not every chemical plant worries about residual solvent profiles, but our experience shows that even a trace of unanticipated material can throw off large-scale synthesis or registration studies. So we built our process to respond quickly—if a shipment ever lands outside a parameter, our teams jump into root cause analysis, adjust the cycle, and prefer quality over volume, every time.
We know many customers have small batch needs. Our flexible plant layout allows us to respond to these requests, switching over to clean lines quickly and minimizing cross-contamination risk. Thanks to our team’s familiarity with both small- and large-scale runs, we often spot scale-up risks early, flagging them for our customers and offering advice based on firsthand plant-floor observations. These aren’t just empty reassurances—it’s the result of walking these lines daily.
Customers sometimes come to us uncertain about whether 5-methoxy-2-nitrobenzoic acid fits their protocol better than a chlorinated or plain nitro derivative. We don’t just quote numbers; we ask about reaction conditions, planned regulatory requirements, and solvent compatibility. We pull from our own process trials—recounting times a change in temperature or pH yielded surprising results—so researchers and production teams understand not just the data, but the story behind it. When customers debate between different methoxy or nitro benzoic acids for esterification or amidation, we offer case studies from previous campaigns that reveal yields, side products, and cost breakdowns. This is knowledge only a manufacturer with their own process and data can supply.
Occasionally, customers report difficulties not covered in academic literature. Pinpointing batch variability or contamination sources requires hands-on knowledge—access to internal plant logs, the ability to recreate runs, and staff who know every detail of the line setup. This manufacturer’s perspective keeps us honest, letting us improve not just what leaves our door, but often, the processes our customers run years later.
We’ve also faced tough conversations about price, as global supply and demand shifts and raw material markets grow more volatile. Our direct manufacturing position puts us in the room during rare outages, price spikes, and shipping snarls. Instead of passing blame, we supply real-time information and options, helping our customers strategize during market disruptions. This approach has built partnerships that last beyond single orders, supporting reliability for those whose programs depend on a stable source.
In the fine chemical world, regulations, innovation, and customer needs never stand still. Over the years, we’ve seen growing emphasis on traceability and environmental responsibility. Our shift toward greener solvents and milder reagents didn't happen overnight. We piloted multiple small-scale trials, measured environmental outputs, and involved shop-floor teams in every improvement review. These efforts sharpened product quality while reducing our plant’s ecological impact. Customers value this focus, particularly those participating in global registration programs or seeking to lower environmental footprints throughout their supply chain.
Process security is an ongoing journey. For example, when we began exporting to overseas clients with tight customs rules, our logkeeping and material ID systems went digital. A misplaced drum or a missing barcode isn’t just an annoyance—it can be a deal-breaker for a client's supply chain. Our experience has shown that investment in these systems pays off when audits come, and our process transparency prevents small errors from becoming major issues down the line.
Sample testing and customer feedback have always driven our cycle of review. We keep back-ups of each batch, allowing us or our partners to rerun analytical checks or regulatory studies long after a delivery is complete. In this way, we’ve built trust not just with R&D heavyweights, but also with those pushing new compound registrations or non-standard protocols. Whether it’s tweaking our production method to support a novel drug program or rechecking archive samples related to a regulatory question, our plant’s infrastructure supports long-term scientific collaboration.
More than once, our customers have switched from third-party suppliers after facing setbacks due to inconsistent batches or missing documentation. As a direct manufacturer, we see the ripple effects of such breakdowns. We keep our lines clear, our logs detailed, and our communication straightforward. We encourage customer visits to our site, offering firsthand transparency about our processes and quality routines. These visits have sometimes led to operational improvements and fostered mutual respect between our chemists and our customers’ teams.
By staying close to the manufacturing line, we remain connected to the realities our customers face. This approach lets us adapt quickly, solve problems at their source, and build products that go beyond technical specs. In many ways, 5-methoxy-2-nitrobenzoic acid has become a showcase for how process control, transparency, and partnership can drive quality and results.
Some see specialty chemicals as a commodity, but those of us who make them know real difference comes from experience, care, and continuous learning. Every production run for 5-methoxy-2-nitrobenzoic acid reflects what we’ve learned on the ground. A successful product stands on the shoulders of the plant team, R&D feedback, and real-world use cases.
From the earliest steps in synthesis through rigorous quality control, our production methods build in reliability. Our focus on process detail helps downstream chemists avoid complications—be it a subtle impurity, a moisture variance, or an unexpected trace element. Feedback from pharma and agri tech users guides our process tweaks, and open communication ensures we remain on top of global shifts in regulation and innovation.
We stand behind our 5-methoxy-2-nitrobenzoic acid not because it meets a list of technical requirements, but because we know firsthand the effort, expertise, and teamwork it takes to solve real world problems our customers face every day.