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5-Formyl-2-Furancarboxylic Acid

    • Product Name 5-Formyl-2-Furancarboxylic Acid
    • Alias 5-Formylfuran-2-carboxylic acid
    • Einecs 234-196-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    285848

    Chemical Name 5-Formyl-2-Furancarboxylic Acid
    Synonyms 5-Formylfuran-2-carboxylic acid
    Molecular Formula C6H4O4
    Molecular Weight 140.09 g/mol
    Cas Number 1824-43-1
    Appearance Light yellow to brown solid
    Melting Point 214-218°C
    Solubility In Water Slightly soluble
    Storage Conditions Store at room temperature, keep container tightly closed

    As an accredited 5-Formyl-2-Furancarboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 5-Formyl-2-Furancarboxylic Acid is packaged in a 25g amber glass bottle with a secure, tamper-evident screw cap.
    Shipping 5-Formyl-2-Furancarboxylic Acid is shipped in tightly sealed containers to prevent moisture and contamination. The chemical should be stored and transported at room temperature, protected from light and incompatible substances. All packages are clearly labeled according to hazardous material regulations to ensure safe handling and compliance with global shipping standards.
    Storage 5-Formyl-2-Furancarboxylic acid should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers and bases. Store at room temperature (or as specified by the manufacturer), and ensure proper chemical labeling to avoid accidental misuse or contamination.
    Application of 5-Formyl-2-Furancarboxylic Acid

    Applications of 5-Formyl-2-Furancarboxylic Acid in Industrial Manufacturing

    5-Formyl-2-Furancarboxylic Acid serves as an advanced intermediate across select chemical sectors where heterocyclic aldehyde functionalities offer conversion pathways to value-added compounds. Our production supports stringent supply chain traceability, and our technical team works alongside formulation chemists and plant operators to optimize specification fit across high-volume and specialty lines. Below, we outline real-world industrial applications with essential integration parameters.

    1. Pharmaceutical API Intermediate Synthesis

    This furan derivative functions as a critical building block in the synthesis of specialized pharmaceutical intermediates, predominantly in non-β-lactam antibacterial and certain antiviral agent pathways. Dehydrogenation and subsequent condensation reactions allow for selective modification of the molecule during the multi-step small molecule API manufacturing. The material’s high purity grade, ensured by photographic and chiral HPLC analytics, minimizes downstream impurity burden and helps streamline regulatory filing for finished drug substances.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia monographs for intermediates
    • US FDA 21 CFR Part 210/211 for pharmaceutical quality systems
    • REACH registration for non-exempt intermediates in the EU

    Typical usage ratio

    • Between 2.5–9% by mass in intermediate coupling or cyclization steps; actual ratio determined by target molecule yield optimization and impurity profile control

    Downstream process integration

    • Introduced post-protection or post-activation of core scaffold, typically in step 3–7 of multi-step synthesis for target pharmaceuticals, depending on the route

    Final product types

    • Non-β-lactam antibacterial intermediates
    • Antiviral precursor compounds
    • Chiral late-stage intermediates for proprietary APIs

    2. Fine Chemical Synthesis for Heterocyclic Compound Libraries

    Synthetic organic laboratories and custom manufacturing partners value this material as a feedstock for the construction of furan-based heterocycles that serve in agrochemical actives screening, dye structure investigation, and advanced material precursors. Its aldehyde group is readily modified under mild conditions, giving access to a wide array of substituted and fused heterocyclic systems with precise regiochemistry.

    Industry compliance standards

    • ISO 9001:2015 Quality Management System (Fine Chemicals)
    • Responsible Care Global Charter (chemical safety)
    • Occupational exposure limits as per ACGIH (for handling and processing)
    • REACH annex compliance for R&D substances (Europe)

    Typical usage ratio

    • Commonly 1.2–6% w/w in coupling, cyclization, or reduction reactions; adjusted to reactivity of core structure and functional group tolerance

    Downstream process integration

    • Dosed in batch reactors during early-stage library construction, often following protecting-group chemistry or as the initiating nucleophile/electrophile

    Final product types

    • Agrochemical lead molecule libraries
    • Dye and pigment intermediates
    • Electronic organic material screening compounds

    3. Resin and Polymer Crosslinking Component

    As a bifunctional monomer, 5-Formyl-2-Furancarboxylic Acid is used in specialized aromatic and furanic resin compositions, especially thermosetting polymers where controlled crosslink formation contributes to improved solvent resistance and mechanical properties. The aldehyde moiety offers unique reactivity toward amines and hydrazines, creating stable covalent bridges within cured matrices during resin formulation and molded part production.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management (chemical processing)
    • EN 1889-2 (Resins for electric and electronic applications)
    • Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) for monomers and polymers
    • UL 94 Flame Class for polymeric materials

    Typical usage ratio

    • 0.7–3.2% by mass in final resin/polymer blends; ratio tuned for the required crosslink density and physical performance of molded parts or coatings

    Downstream process integration

    • Added to prepolymer mixtures ahead of final cure; may be co-reacted with polyols, amines, or other aldehyde-reactive partners under thermal or catalytic conditions

    Final product types

    • Thermoset polymer panels for electronics
    • Chemical-resistant industrial coatings
    • Crosslinked composite matrix resins

    4. Food Contact Material Additive in PET and Bio-based Polyester Chains

    Certification-grade material enters reaction with diols as an intermediate during polycondensation to yield polyester copolymers, including high-performance PET and novel bio-based resins. It introduces controlled furan ring content into the polymer backbone, enhancing UV stability and mechanical strength for select food packaging films and containers. Compliance with food contact and migration limits is tested in the final application.

    Industry compliance standards

    • US FDA 21 CFR 177.1630 (Polyethylene terephthalate)
    • European Regulation (EU) No 10/2011 on plastic materials for food contact
    • EFSA Guidance on Food Contact Materials
    • TÜV SÜD food-safe migration testing

    Typical usage ratio

    • 0.1–1.8% molar ratio in esterification mixtures; exact proportion depends on required furan content and film end-use migration testing

    Downstream process integration

    • Fed into polycondensation reactors with PTA (terephthalic acid) and ethylene glycol, leading to copolyester pellet or film grades for food packaging conversion

    Final product types

    • Biaxially oriented PET (BOPET) food films
    • Bio-based PET bottle preforms
    • High-barrier food trays and containers

    5. Chemical Sensor Dye Intermediate

    Downstream sensor and colorant manufacturers use this aldehyde as a starting point for synthesizing chromophoric furan derivatives incorporated into specialty sensor dyes. Functional group transformations yield compounds displaying high selectivity for detecting metal ions or pH fluctuations in industrial or environmental monitoring devices. Stringent manufacturing and analytical controls support consistent dye performance.

    Industry compliance standards

    • ISO 13485 for sensor materials (when medical device integrated)
    • DIN EN ISO 9001:2015 for chemical production and QC
    • Directive 2011/65/EU (RoHS) for electronics
    • ASTM E2877: Standard Guide for Chemical Sensors

    Typical usage ratio

    • Range from 0.4–3% by mass in initial dye coupling batches; yield and sensor calibration targets influence adjustment

    Downstream process integration

    • Engaged as the functionalized heterocyclic precursor during condensation or azo coupling steps in precision dye synthesis

    Final product types

    • Chromogenic sensor dyes for metal ion detection
    • Textile pH-indicator labels
    • Colorimetric test strips for water quality kits
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    Certification & Compliance
    More Introduction

    5-Formyl-2-Furancarboxylic Acid: Practical Value from Source to Application

    Since 5-Formyl-2-Furancarboxylic Acid earned interest in specialty synthesis years back, we have invested considerable time and resources into improving both its quality and reliability. Every batch we produce reflects real experience in handling every challenge this furan-based aldehyde throws at us—from starting material supply chain all the way through purification. We do not treat it as a commodity but as the backbone of advanced chemical transformations where final purity, lot traceability, and process suitability actually matter.

    How Our Background Shapes What We Offer

    We started making 5-Formyl-2-Furancarboxylic Acid after research customers and pharmaceutical process developers asked for genuine consistency batch after batch. In the early days, yield swings and minor impurities used to plague final runs. Our answer relied on real tweaks—temperature profile adjustments, solvent selection informed by small scale analytics, and closer monitoring of reaction intermediates, not borrowed formulas. We built the process on the bench and scaled with the results in hand. Each kilogram we now ship reflects that ground-up approach, forged by what actually works under plant conditions, not just what reads well on a spec sheet.

    Specifications That Reflect Practical Choices

    Production quality for this material matters because it directly impacts downstream syntheses, especially where trace aldehyde reactivity or furan ring integrity play pivotal roles. We place purity metrics—by HPLC, NMR, and Karl Fischer moisture analysis—at the front of our quality program. Lot-to-lot consistency does not emerge by accident. We calibrate drying and filtration to trim away troublesome byproducts while preserving the core aldehyde functionality. Our technical sheets point to a purity above 99%, because research scientists told us long ago that anything lower forced reworking. Moisture control stays tight; simple dryness prevents hydrolysis over time without risking static hazards or dust. Particle sizing keeps the acid manageable in reaction feeds or preps—fine, not clumped, no flow headaches. No batch leaves our facility without full microanalytical confirmation and documentation signed by the people who physically ran the analyses.

    Usage: Where Experience Matters Most

    5-Formyl-2-Furancarboxylic Acid shows up in places that demand clean, reliable chemical building blocks. We have seen it flow from our plant into diverse laboratories: medicinal chemistry groups searching for new furan-linked scaffolds, polymer developers aiming to incorporate renewable carbon content, and dye and pigment researchers building chromophores. A decade ago, a process chemist pointed out that off-target reduction or condensation reactions can throw off whole synthetic routes if trace contaminants disrupt formyl reactivity. For applications like API synthesis or fine chemical intermediates, that formyl group’s stability and predictable reactivity aren't abstract requirements: they translate directly into the ability to achieve target yields or avoid failed batches. Only steady supply—uncontaminated by residual starting furan or oxidized byproducts—gives these customers control over their own processes.

    Our Approach to Customer Feedback

    Years of dialogue with technical buyers and end users have shaped far more than our paperwork. We keep our focus on avoiding the “hidden” impurities or inconsistent physical form that slow down or jeopardize final product yields. Chemists in both research and full-scale production repeatedly ask for tailored support, not just deliveries. Our technical team understands what it means when an acid carries over traces of synthetic byproducts or dries to a lumpy residue: issues from slow dissolution in reaction vessels to inconsistent titration values. Whenever customers expressed concerns, our line operators worked alongside R&D and analytics staff to trace down root causes—sometimes requiring weeks of bench work. That diligence builds an acid that not only matches tight chemical criteria but fits into real-world research and scale-up processes.

    What Sets This Acid Apart From Similar Compounds

    The world of furan derivatives includes dozens of closely related compounds, but 5-Formyl-2-Furancarboxylic Acid offers a unique functional group setup. Its 5-position formyl group makes it a versatile bridge in forming carbon-carbon or carbon-nitrogen bonds, and its carboxylic acid holds steady through many synthetic schemes. Unlike the non-formylated furancarboxylic acids—like simple 2-furancarboxylic acid—ours enables routes to aminated, condensed, or halogenated heterocycles not easily accessed otherwise. 5-Formyl-2-Furancarboxaldehyde, a related compound, suffers from higher volatility and instability; it can decompose or create storage headaches, particularly when heat or prolonged exposure occurs. Customers with experience in multi-step syntheses tell us the stability window of our acid lets them hold inventory or plan longer campaigns, instead of constantly reordering or rushing through sensitive manipulations.

    Real Challenges Behind Consistent Production

    Producing rare heterocyclic acids draws on more than theoretical expertise. Raw materials, especially furfural-derived precursors, need strict vetting. Unwanted trace metals from vessel alloys or residual solvents affect whether the 5-formyl group carries over unaltered. We install inline testing at multiple checkpoints—cutting off subpar batches before they reach the final purification step. For larger scale orders, we work closely with logistics and warehousing to block moisture ingress, which can lead to clumping, hydrolytic breakdown, or pH drift. Every improvement reflects repeatedly running the process, not a one-size-fits-all fix. Knowing exactly which impurity peaks to target—those odd signals under NMR or hidden traces in LC-MS—comes from watching what hurts downstream chemistry, not relying on broad generalizations.

    How Our Product Fits Into Changing Industry Needs

    As regulatory landscapes shift and greener synthesis trends gain traction, the source and processing history of every kilogram of specialty acid matters more than ever. Labs pursuing renewable-chemistry goals appreciate our clear traceability—backed with documentation, not unverified claims. In scale-up operations or new materials development, reliable access means never compromising on experimental design. Feedback from both seasoned researchers and newcomers has led us to further tighten controls around chlorinated byproducts, especially as end applications broaden into food packaging, medical devices, and consumer goods. Each new application provides insights—one polymer startup found excessive fines (oversized dust) fouled their reactors, so we tailored our sieving and drying process to produce a less statically charged batch. Direct, functional feedback loop drives us to tune not just purity but actual usability in client workflows.

    Risk Management in Synthesis and Storage

    From our handling bays to outbound shipments, safety and stability remain at the top of our operating discipline. This acid’s mild irritancy and reactivity can surprise less seasoned handlers. We remind every receiving lab of its reactivity profile and avoid shipment of material outside its safe moisture and particle counts. Our process operators wear PPE, and we design workup steps to confine dust, minimizing both airborne risks and product loss. For R&D clients who store our material for months, we’ve found that low-level acid decomposition often tracks to headspace humidity. Careful sealing and scheduled stock rotation keep the product ready-to-use—no need to rescrub or recover from partial breakdown. Every choice aims to prevent surprise costs or delays, not just check boxes on hazard forms.

    Working Directly With Innovators

    Chemists pushing the envelope in pharmaceuticals or materials science often need custom packaging, technical modifications, or atypical batch sizes. Since we operate both as producer and in-house problem-solver, we field these requests quickly. We have packed kilogram to multi-ton quantities, always under cleanroom-derived protocols where the end-application calls for it. Once, a specialty pigment manufacturer required precise water activity levels for their process; by running multiple small trial batches, we identified the right endpoint, then scaled it reliably. In our plant, those kinds of tweaks are not a disruption—they are part of our baseline workflow, formed over years of hearing what does and does not actually make a difference in our customers’ labs and factories.

    Supporting Technical Development and Academic Progress

    Collaborations with universities and independent research groups help both sides. We notice which analytical questions recur—residual solvent profile, catalytic trace carryover, or shelf-life under variable conditions. Instead of generic customer service lines, we provide files, methods, and technical guidance tailored to the actual synthetic sequences being attempted. Grant-funded projects, scale-up runs, and proof-of-concept batches each pose distinct questions about the acid’s handling and integration. Students and early-stage companies in emerging markets often seek detailed Q&A before even trialing a purchase. We respect that skepticism—if our own process team would ask for that data, any researcher deserves the same clarity. Years of direct support for grant proposals, journal submissions, and patent disputes keep us focused on technical transparency and accuracy in every interaction.

    Raw Material Sourcing With Long-Term Security

    Supply chains in specialty chemicals do not run on autopilot. Our experience during the past decade’s transport disruptions taught us to diversify sources of our core furan building blocks. We maintain always-on relationships with vetted suppliers from multiple regions, regularly auditing for contaminant profiles, trace metal content, and compliance with international manufacturing standards. Our commitment to sustainable sourcing grows from years of direct requests—from multinational corporations down to individual lab customers—for clear documentation on starting materials. Every order we produce comes with a full sourcing report. By handling supplier relationships in-house, rather than relying on third parties, we close off the risk of off-specification material entering our reactors or endangering customers’ outcomes.

    Continuous Process Improvement Driven By Customer Needs

    Routine does not spell complacency. We adjust, trial, and invest whenever customer outcomes or batch data suggest gain. Analytical feedback loops between plant floor and QC labs guide equipment upgrades, raw material adjustments, and reaction optimization. We conduct root-cause investigations on any batch not meeting expectations, whether flagged internally or by clients. Those lessons go back to all future runs. One pharmaceutical partner flagged a persistent low-level impurity that only showed up during their unique downstream processing—not on our standard tests. We modified chromatography methods and worked back through each unit operation until the trace was eliminated, saving both sides cost and time on reanalysis and troubleshooting.

    Why Our Scale Brings Practical Benefits

    Compared to small-batch resellers or virtual traders, our in-house synthesis and purification lines allow fast, reliable scale-up without diluting quality. Custom requests can graduate from gram to ton under the same physical and analytical oversight. We minimize holding time between production and dispatch, dropping the risk of batch degradation. Packaging follows what's needed in the real world—not just foil pouches, but lined fiber drums, anti-static bags, or inert gas overlays, always based on solvent compatibility, storage duration, and end-user equipment. Our scale also enables participation in technical working groups, standards development, and supply risk mitigation programs, directly benefiting downstream users in regulated and competitive industries.

    Tackling Environmental Questions Head-On

    Regulatory compliance extends well beyond checklists. Limiting environmental footprint shapes our energy and solvent recycling choices. We minimize waste, route spent solvents through in-house reclamation, and design preventive maintenance schedules that cut down on unscheduled emissions. Supply agreements with eco-focused clients have led us to voluntarily tighten wastewater discharge thresholds. By systematically documenting both emissions and energy use—and publishing this data for select clients—we enable transparent reporting up and down modern supply networks. Years of effort toward circular chemistry models pay off in both regulatory compliance and long-term cost control, a lesson only earned from hands-on experience in the evolving chemical landscape.

    Direct Communication Beats Guesswork Every Time

    Our sales and technical teams talk, often daily, with process engineers and researchers using 5-Formyl-2-Furancarboxylic Acid in demanding scenarios. We do not hide behind generic responses or forward queries down the line. Each feedback note, technical concern, or specification request returns to the core group responsible for production and QC. Experience tells us that hands-on, transparent responses solve issues faster, lower risk, and foster genuine trust. Whether discussing batch requalification, alternate particle sizes, or atypical certificate formats, we always prioritize clarity and responsiveness. The best technical outcomes almost always trace to early, open communication—not rote commitments or ambiguous service promises.

    Staying Ahead Through Industry Partnerships

    Long-term relationships with innovators, scale-up facilities, and research consortia allow us to forecast both new technical requirements and broader market shifts. Insights from joint ventures, standards-setting panels, and customer R&D keeps our staff aware of both incremental and seismic changes affecting furan chemistry and specialty acid synthesis. We use these partnerships to feed back best practices into our process controls, hazard assessment, and even external audit routines. Our readiness to take on new challenges stems from experience, not marketing: every technical advance or compliance update earns its place through testing and confirmation in our own facility—never “beta-tested” on clients or outsourced to unknown third parties.

    Final Thoughts from the Manufacturing Line

    Producing 5-Formyl-2-Furancarboxylic Acid earns us more than business: it sharpens our technical judgment and connects us directly with the real decision-makers—chemists, engineers, and process designers who transform raw material into innovation. Our commitment to transparency, technical support, and honest improvements drives every kilogram that leaves our doors. Trials, feedback, and constant curiosity ensure our acid evolves alongside the industries that use it, not behind them. It stands apart not because of abstract descriptors or surface-level specification claims, but because every detail comes from real, on-the-ground problem solving and long-term collaboration with those who rely on us to get the chemistry right. We stay at the table, work through surprises, and track every improvement back to factory, not just paper. That’s the only way we know to make a specialty chemical fit for today’s demands—and adaptable to tomorrow’s discoveries.