Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid

    • Product Name 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid
    • Alias 5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
    • Einecs 613-415-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    529156

    Productname 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid
    Molecularformula C8H9NO3
    Molecularweight 167.16 g/mol
    Casnumber 1080657-28-2
    Appearance Solid, typically off-white to light yellow powder
    Solubility Soluble in organic solvents like DMSO and methanol
    Purity Typically ≥ 95% (varies by supplier)
    Structure Pyrrole ring with 2,4-dimethyl, 3-carboxy, and 5-formyl substituents
    Smiles CC1=CC(=C(N1)C=O)C(=O)O
    Inchi InChI=1S/C8H9NO3/c1-4-5(3-10)7(8(11)12)6(2)9-4/h3,9H,1-2H3,(H,11,12)
    Storageconditions Store at 2-8°C, protected from light and moisture
    Application Intermediate in organic synthesis; research chemical

    As an accredited 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 500 mg of 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid, sealed with a screw cap, labeled.
    Shipping The chemical **5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid** is shipped in secure, airtight containers to prevent moisture and contamination. It is typically dispatched as a solid at ambient temperature, with customized packing compliant with safety and regulatory guidelines. Appropriate hazard documentation accompanies each shipment to ensure safe transport and handling.
    Storage 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid should be stored in a cool, dry, well-ventilated area, away from direct sunlight and sources of heat or ignition. Keep the container tightly closed and protected from moisture. Store separately from incompatible substances such as strong oxidizing agents. Use appropriate labeling and safety precautions to avoid accidental exposure or contamination.
    Application of 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid

    Applications of 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid in Industrial Manufacturing

    As a direct producer, we supply 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid to well-established downstream industries with proven demand for pyrrole derivatives. The following application fields reflect real-world usage based on our production experience, customer specifications, and integration into advanced manufacturing processes.

    1. Active Pharmaceutical Ingredient (API) Synthesis for Heterocyclic Drug Scaffolding

    Pharmaceutical manufacturers rely on this material as a pyrrole-carbonyl scaffold during multi-step organic synthesis of antimicrobial and anti-inflammatory APIs. Its unique formyl and carboxylic groups enable specific coupling and ring closure reactions, supporting the creation of complex heterocyclic molecules under regulated quality systems.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • European Pharmacopoeia (Ph. Eur.) relevant monographs
    • US FDA cGMP 21 CFR Part 211
    • Chinese Pharmacopoeia guidelines for intermediates

    Typical usage ratio

    • Usually 0.1–0.25 molar equivalents relative to target API core structure
    • Adjusted per batch scale and specific synthetic route

    Downstream process integration

    • Used in early to mid-stage synthesis for forming functionalized pyrrole rings
    • Acts as coupling or formylation intermediate prior to cyclization/hydrolysis
    • Integrated into GMP-compliant closed reactor systems

    Final product types

    • Bespoke antimicrobial drug intermediates
    • Synthetic anti-inflammatory compound scaffolds
    • Targeted oncology drug candidates using pyrrole backbones

    2. Specialty Dye and Pigment Intermediate Manufacturing

    Color chemistry producers integrate this pyrrole acid in the formation of novel pigment molecules, especially for high-performance azo and phthalocyanine dyes. Its dimethyl-pyrrole structure offers selective pathways for coupling with diazonium salts or phthalic anhydride during pigment synthesis, ensuring color purity and fastness for advanced textiles and coating applications.

    Industry compliance standards

    • OEKO-TEX® Standard 100 restricted substance list
    • REACH (EC) No 1907/2006 substance registration
    • ISO 105 color fastness series for textiles
    • BS EN 71-3:2019 for colorants used in coated toys

    Typical usage ratio

    • 0.5–3% by weight in pigment batch depending on desired chroma and substrate compatibility
    • Adjusted empirically for specific shade depth and dispersion requirements

    Downstream process integration

    • Dosed directly to diazotization or condensation reaction vessels
    • Participates in regulated synthesis under nitrogen or argon atmospheres
    • Buffered aqueous or solvent conditions control reactivity

    Final product types

    • High-purity textile dyes for performance fabrics
    • Organic pigments for industrial coatings and inks
    • Phthalocyanine green and blue series for plastics and paints

    3. Agrochemical Intermediate for Heterocyclic Active Substances

    Major agrochemical formulators process this pyrrole derivative as an intermediate in the design and synthesis of herbicide and insecticide actives. Its functionality allows for attachment to various aryl halides or other building blocks using controlled, moisture-free reactions, supporting the development of crop protection ingredients requiring strict traceability and quality.

    Industry compliance standards

    • FAO/WHO Technical Guidelines for pesticide intermediates
    • ISO 9001:2015 for agrochemical production sites
    • Globally Harmonized System (GHS) labeling during storage/processing
    • EU Regulation (EC) No 1107/2009 for plant protection products

    Typical usage ratio

    • Ranging from 2–10% by weight in intermediate synthesis stages
    • Quantity scaled by targeted loading for each specific actives’ molecular design

    Downstream process integration

    • Reacted in anhydrous conditions to minimize hydrolysis risk
    • Used as a block in Suzuki coupling or cyclization sequences
    • Monitored via HPLC or GC for residual purification

    Final product types

    • Advanced heterocyclic herbicide actives
    • Pyrrole-based insecticide intermediates
    • Synergist adjuvants for crop protection blends

    4. Photovoltaic and OLED Material Precursor

    Manufacturers in the electronic materials sector incorporate this pyrrole derivative to construct conjugated organic structures essential for organic photovoltaic (OPV) and OLED device layers. Its chemical configuration facilitates functional group transformations and controlled polymerization for electronic grade films and light emitting layers, with careful process monitoring to match device fabrication standards.

    Industry compliance standards

    • RoHS 2011/65/EU restrictions for hazardous substances
    • IEC 61249-2-21 for halogen-free electronics
    • ISO 9001 for advanced material manufacturing
    • JEDEC JESD625 for electronic component handling

    Typical usage ratio

    • 1–10% by mass in precursor polymer/feedstock formulation
    • Adjusted per molecular weight targets and device efficiency studies

    Downstream process integration

    • Undergoes oxidation or cross-coupling to introduce key electronic functionalities
    • Mixed in solvent systems under inert gas; purity confirmed via LC-MS
    • Fed into continuous polymerization reactors for device-grade materials

    Final product types

    • Pyrrole-based hole transport materials for OLEDs
    • Conjugated small molecules and polymers for OPV cell layers
    • Organic semiconductors for flexible electronics

    5. Analytical Standards and Laboratory Reference Compounds

    Specialty labs and R&D centers order this compound in small-to-medium lots for use as reference standards, calibration compounds, and synthetic control molecules. Its defined structure and analytical signature support method development for LC, GC, and spectroscopic assays targeting pyrrole-containing molecules in quality control and forensic investigations.

    Industry compliance standards

    • ISO/IEC 17025 laboratory accreditation
    • USP general chapter <1062> for analytical reference standards
    • Good Laboratory Practice (GLP, OECD principles)
    • ISO Guide 34 (Certified Reference Materials)

    Typical usage ratio

    • Used at mg to g scale per analytical batch, according to instrument detection sensitivity
    • Solution standards prepared at 1–100 ppm for calibration curves

    Downstream process integration

    • Dissolved/mastered into analytical-grade solvents
    • Applied directly for method validation, calibration, and recovery analysis
    • Referenced in documentation for traceability and routine QC

    Final product types

    • Laboratory calibration solutions
    • Certified reference materials
    • Analytical quality control standards for pharmaceutical and environmental labs
    Free Quote

    Competitive 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid: Straight from the Source

    Drawing From Experience at the Production Level

    From where we stand in the production facility, the creation and supply of 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid stand as proof of years spent fine-tuning chemical synthesis. Commercial applications rarely wait for trends—they demand steady performance, clear composition, and process reliability. Our team approaches this pyrrole derivative with a hands-on familiarity, knowing what matters to our customers is more than a number or a generic lookalike. Day in, day out, we see the role this compound plays in specialty synthesis and scientific research.

    Getting the Specifications Straight Without the Hype

    At our facility, the model available reflects our most widely supplied configuration. Most orders draw on a solid form with purity consistently tracked above 98% by HPLC and confirmed through NMR. Each batch is characterized by a light to moderate yellow hue—a visible signal of controlled handling and absence of trace contamination. Manufacturing targets the formula C8H9NO3, with a molecular weight of 167.17 g/mol. Our process eliminates lingering starting material, safeguarding downstream researchers against unexpected side products.

    Unlike offerings that get rerouted through trading houses or multiple repackagers, our shipments head out fresh, right after final QC approval. No unexplained “mystery solvents,” no last-mile contamination, and immediate support for application-specific needs. Specialist buyers often remark on the physical consistency—powder, not lumpy or hygroscopic—which makes for stable weighing and easier integration into reaction setups. This comes from air filtration and controlled atmosphere drying, techniques we added after recognizing stickiness in batches from uncontrolled storage during our earliest production runs.

    Role in Science and Process Industries

    Requests for 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid flow in from both research laboratories and pilot production lines. Prime uses rest with advanced organic synthesis: creating ligands, investigating enzyme inhibition pathways, fabricating small-molecule libraries, and building blocks for natural product analogs. Over the last few years, some top-tier medicinal chemists have used this very compound as a pivot in iterative drug discovery projects, seizing on the stability of the dimethyl and formyl groups to position it for functionalization.

    Students working on combinatorial chemistry note the clean NMR signature and reproducibility as a standout. In our view, those results don’t happen by accident; they depend on high-performance filtration and controlled crystallization, maintained batch after batch. Some partners have also found emerging opportunities in dye and pigment research, leveraging the electron-rich pyrrole core for tailored color creation. Throughout, each run carries our hallmark: nothing leaves the site unless it meets our agreed standards for purity, structure, and storage stability.

    What Sets Our Material Apart From Other Products?

    On paper, multiple sources can offer this same IUPAC name or CAS number. In practice, differences emerge fast, and they matter most to those relying on data-driven outcomes. We keep full traceability documented for every batch, right down to raw material lot numbers and process log sheets. Many customers share stories about issues with material from indirect channels: compromised color, persistent odor, or unexplained peak clusters in analysis. Delays in research, wasted reagents, and frustrated project timelines often bring them seeking direct supply from someone who takes production seriously.

    We do not cut corners on environmental controls—meaning, no risk of atmospheric moisture sneaking into the pack, no broad-spectrum packaging chosen for only short shipments. Our operations ran into challenges when we first started out: a few early shipments in ordinary bags arrived with mild clumps or musty smell. That taught us to upgrade to aluminum foil liners and vacuum seals as the standard, not as a cost option. Every decision about handling or storage sprang from lessons learned and direct feedback from users handling gram-to-multikilogram lots in their daily work.

    Distinguishing our 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid comes back to this: we stand by what leaves our floor. Batch certificates come with more than basic data—a genuine record of NMR structure, IR trace, HPLC chromatograms, and moisture analysis. Customers know what expectations match reality. Over time, we built up a bank of experience tracking anomalies, such as low-level oxidizable byproducts, which can show up if storage isn’t managed tightly. To us, preventing such factors is not a bonus, but part of building real, dependable E-E-A-T into our work.

    Working With Real Requirements

    Running a chemical manufacturing line means never settling for typical. Customers return when they trust every source of error has been squeezed out. That pushed us toward more rigorous filtration, lock-step temperature control during crystallization, and batchwise testing, not just sampling the top or bottom of a drum. Scientists and process engineers investing in peptide synthesis or heterocyclic modifications base their projects on our material’s consistency. The feedback loop goes both ways: a client struggles with solubility or reactivity profiles, and we evaluate sample splits—helping isolate the factors that could hinder reproducibility, whether it be trace diols, water, or alien aromatic residues.

    From our perspective, providing this standard of service involves more than listing purity numbers. Clear documentation—ranging from NMR spectra to elemental microanalysis—gets delivered with each purchase. Some competing materials barely reference beyond a warehouse re-inventory; we give batch-level chromatograms and history.

    Why Exacting Attention Matters in Niche Compounds

    Our direct relationship with buyers tells us the role of small-quantity, high-purity chemicals can rarely be overstated. In fields like medicinal chemistry, even minor deviation in substitution can derail weeks of synthetic effort. Method development relies on knowing reagents provide exactly what is needed, no surprises. This compound, 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid, finds itself at the intersection of method validation and experimental design for companies pushing new frontiers in drug candidates or diagnostics.

    R&D managers cannot risk lower yield or unplanned side reactions traced to a careless impurity profile. Projects have stalled after switching to intermediates from a broker with mismatched documentation or incorrect labeling. On our end, batch documentation runs beyond a standard COA: each lot includes spectral overlays showing batch-to-batch consistency, helping customers correlate their spectra instantly.

    Tales circulate about shipments arriving with incorrect melting ranges, or materials that require double purification before use. We view those as system failures. The production floor here focuses on real-world demands—care in synthesis, filtration, drying, packing. By giving research chemists the foundation to trust the underlying building block, they can shift energy to innovation, not troubleshooting.

    Addressing Problems That Actually Arise

    Every manufacturer runs into hiccups. In the early days, we ran a few batches that absorbed more humidity than expected, later traced to a minor deviation in drying cycle duration. Our SOPs changed overnight. Each lesson forced us to build smarter controls—in-process water content checks, new desiccants, and tighter packaging QA. When a client reported inconsistent color from another supplier, we ran stress tests on samples under different lighting and exposure conditions, ruling out oxidation versus off-gassing as the culprit.

    Technical support means a real conversation, not an anonymous ticket. Synthesis teams often reach out with questions about solubility in various solvents, notice odd artifacts in their DMSO spectra, or look for pre-approval of in-house analytical methods set for this compound. Our technical group gets involved directly, comparing hand-run trials in our own labs against customer setups. That hands-on approach lets us troubleshoot obscure issues fast, whether by cross-checking storage containers, refining atmospheric conditions, or switching drying filters.

    How Applications Evolve With Reliable Material

    Several research groups use this acid as a point of departure for new pyrrole-based drugs. Side chains and formyl positions enable diverse transformations—a fact demonstrated by published work referencing this material as a precursor in heterocycle libraries. Bioconjugation teams push it into intermediate steps for more advanced linking strategies. Materials scientists look for the predictable reactivity needed in dye design, pursuing repeatable synthesis sequences where only a clean, moisture-stable aldehyde will do.

    The more trust we build batch after batch, the more projects push the complexity envelope: photolabile conjugates, ligand docking studies, or template-directed synthesis. Throughout, research thrives on a transparent trail: one that logs every chromatogram, every prep detail, every shipping temperature. Without that, feedback spirals into time lost and frustration. Our experience reminds us to build everything on the solid baseline that comes from direct manufacturer-to-end-user flow.

    Addressing Comparison With Bulk-Traded Products

    Commodity chemicals may satisfy undemanding routine. That approach falls short where data integrity, reproducibility, and safety are paramount. Recounting customer stories, issues surface around misleading product descriptions masking blend lots, missing quality reports, or inconsistently sized containers. These issues can go unnoticed until a key experiment fails. Our operation shifted wholesale toward traceable batches—each one marked at source, with documentation running through production line to package seal.

    This tight control allows us to answer questions authoritatively: Where did this lot originate? What controls supported it? Can analytical results be tied back unambiguously to one production run? For those whose livelihoods and reputations rest on experimental quality, that information forms the foundation of working partnerships.

    Quality Control: Not Just a Check Box

    In practice, our QC system evolved to track not only assay values, but also particle morphology, filtration clarity, and moisture drift over time. Early reliability challenges shaped our present standards. It has never been enough to rest on generic checks or pro forma documentation. Reviews from long-time partners drove us to automate moisture testing, calibrate HPLC retention time against validated external standards, and preserve authentic spectra from pilot to full production scale.

    Each container carries a guarantee based on real world usage. Pharmaceutical clients have flagged, and we have changed, packaging materials when solvent vapor transmission threatened sensitive downstream steps. Manufacturing timelines dovetail with real laboratory planning—loading bays run at scheduled times, with materials staged for shipment immediately post-QC, never left to sit idle.

    Supporting Problem Solvers, Not Speculators

    Manufacturers operate with the end-user in mind, standing ready to provide whatever evidence or clarity research and development teams require. Our material has come to form the basis for pilot production and advanced screening projects in several established groups, always accompanied by direct communication and support. For us, that means answering direct inquiries, not rerouting to anonymous intermediaries, and pulling sample splits or historical documentation at short notice.

    Some buyers ask about in-lab application specifics and seek support for downstream scale-up or process optimization. Our technical personnel maintain direct connections with their research and QA counterparts, drawing from first-hand familiarity and understanding that no process runs perfectly without honest feedback upstream. Every process refinement, every change in milling or drying, arises from these conversations.

    Real World Stories: Lessons From the Factory Floor

    Chemists face all sorts of hurdles: unexpected reactivity, solubility puzzles, packaging artifacts, or even batch-to-batch color drift. By keeping production tightly managed and keeping an ear open to end users, manufacturers adapt steadily. In the early days, a missed standardization step in our drying process led to surface tackiness in some batches—traceable right to complaints in the field about weighing variability. Once caught and addressed, packing and control took a leap forward. The learning never stops.

    Another case, a project on heterocycle coupling kept hitting low yields. Direct dialogue unearthed that a critical impurity, below the sensitivity of a basic TLC, was present in one of the test batches. Our updated methods now include broader scan settings and deeper lot screening to prevent a repeat. Experience breeds vigilance, not complacency.

    All improvements spring from a partnership approach. We don’t view buyers as transaction numbers, but as collaborators in getting good science done reliably. That means being willing to field complaints, chase down root causes, and make process improvements—even when it means extra hours refining what might already seem “good enough.”

    What the Market Truly Values

    Direct-from-manufacturer material secures a level of trust absent from batchless, faceless offerings. Each buyer knows exactly what’s being shipped, when, and how it’s been made. The underlying structure, purity, and performance are not advertising points, but a working guarantee. From our side, every process change and every technical upgrade reflects not just a checklist or a marketing slogan, but a cumulative improvement shaped by hands-on usage and tangible feedback from people doing the chemistry every day.

    Ultimately, 5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid plays a modest but critical role in the toolkit of advanced chemistry. For those probing the outer limits of molecular assembly, the quality of the parts can’t fall short. We keep raising the bar so scientists and product developers aren’t sidetracked by avoidable errors or unreliable supply. This hands-on, end-to-end engagement sets direct manufacturing apart—ensuring that every gram, every analysis, and every conversation keeps projects moving forward, built on proven quality and real partnership.