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5-Dibenzosuberenone

    • Product Name 5-Dibenzosuberenone
    • Alias 10H-Dibenzo[b,f]azepin-5-one
    • Einecs 207-334-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    943801

    Product Name 5-Dibenzosuberenone
    Cas Number 3674-53-7
    Molecular Formula C15H10O
    Molecular Weight 206.24 g/mol
    Appearance Yellow crystalline solid
    Melting Point 164-166°C
    Boiling Point 393.2°C at 760 mmHg
    Density 1.2 g/cm³
    Solubility Insoluble in water, soluble in organic solvents
    Purity Typically ≥98%
    Storage Conditions Store at room temperature, away from light
    Smiles O=C1C2=CC=CC=C2CCC3=CC=CC=C13
    Inchi InChI=1S/C15H10O/c16-15-11-6-2-1-5-10(11)7-8-12-13-9-3-4-14(15)12/h1-6,9H,7-8H2

    As an accredited 5-Dibenzosuberenone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 5-Dibenzosuberenone, 10g, securely sealed in an amber glass bottle with a tamper-evident cap, labeled with safety and handling information.
    Shipping 5-Dibenzosuberenone is shipped in tightly sealed containers to prevent contamination and degradation. Standard procedure includes cushioning material and labeling in accordance with chemical safety regulations. The package is handled as a non-hazardous item and shipped at ambient temperature, unless otherwise specified by the manufacturer or based on local regulatory requirements.
    Storage 5-Dibenzosuberenone should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, ideally at room temperature (15–25°C). Avoid sources of ignition and incompatible substances such as strong oxidizers. Ensure that storage complies with local chemical safety regulations and that access is limited to trained personnel.
    Application of 5-Dibenzosuberenone

    Applications of 5-Dibenzosuberenone in Industrial Manufacturing

    5-Dibenzosuberenone serves as a specialized intermediate with targeted applications in advanced chemical manufacturing sectors. Its molecular structure facilitates key transformations demanded by the pharmaceutical, fine chemical, polymer, pigment, and functional material industries. Below, we detail verified downstream applications supported by regulatory, technical, and usage practice evidence.

    1. Pharmaceutical Intermediate for CNS Drug Synthesis

    Manufacturers use 5-Dibenzosuberenone as an essential building block in multi-step syntheses of central nervous system APIs, including tricyclic compounds targeting neurological disorders. The raw material enters the process during core skeleton construction, enabling cyclization steps critical for the formation of dibenzocycloheptene derivatives. Downstream integration requires precise stoichiometry and stringent adherence to GMP protocols to ensure further reaction to pure, pharmacopeial-compliant APIs.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • 21 CFR Part 211 US cGMP for Finished Pharmaceuticals
    • EU GMP Guideline (Volume 4, Part II)

    Typical usage ratio

    • Reaction molar ratio: 1.0–1.5 equivalents per API intermediate step, optimized to substrate scope and conversion requirements
    • Usage adjusted according to yield targets and impurity profile monitoring

    Downstream process integration

    • Entrance at heterocycle ring-forming phase after initial aromatic substitution
    • Subsequent hydrogenation and functional group modifications utilizing 5-Dibenzosuberenone as the initial core

    Final product types

    • Psychoactive drug substances (tricyclic antidepressants)
    • Antipsychotic intermediates
    • Analytical reference standards for CNS-active molecules

    2. Advanced Organic Synthesis for Fine Chemicals

    Fine chemical producers employ 5-Dibenzosuberenone to generate complex polycyclic intermediates demanded by laboratories and specialty product manufacturers. Its role as a substrate in diketone condensation and asymmetric synthesis is well-established, where controlled reactivity and minimal impurity formation are critical. Processes are often batch-operated under nitrogen, utilizing monitored addition to safeguard product integrity and batch reproducibility for sale to R&D and custom synthesis customers.

    Industry compliance standards

    • ISO 9001 Quality Management System for chemical production
    • REACH Regulation (EC) No 1907/2006 for safe chemical handling
    • Responsible Care program adherence

    Typical usage ratio

    • Normally charged at 5–20% of the reaction substrate mass
    • Ratio optimized using in-process HPLC/GC analysis for target yield versus processing cost

    Downstream process integration

    • Introduced during early-stage cyclization or condensation steps of polycyclic aromatic chemical synthesis
    • Serves as a ketone partner in enolate chemistry for downstream derivatization

    Final product types

    • Research-grade fine chemical intermediates
    • Specialty polyaromatic compounds for analytical laboratories
    • Custom building blocks for academic and contract research

    3. Polymer Additives for High-Performance Materials

    The material acts as a reactive additive in the formulation of engineering polymers where skeletal rigidity and aromatic content are design targets. Compounders incorporate 5-Dibenzosuberenone in melt blending or solution polycondensation, enabling the introduction of suberenone structure into thermoplastic and thermosetting systems. Proper dosing and homogenization are critical to avoid phase separation or migration during downstream plastic conversion.

    Industry compliance standards

    • ISO 14001 Environmental Management System
    • UNI EN ISO 11357 for polymeric additive performance
    • EU REACH Substance Authorization rules for monomeric residues

    Typical usage ratio

    • Loading levels: 0.2–1.0% by weight relative to base polymer, depending on target mechanical and UV resistance properties
    • Adjustment based on matrix compatibility and long-term degradation studies

    Downstream process integration

    • Added at the compounding stage before extrusion, or in resin kettle during polycondensation
    • Monitored by FTIR to confirm uniform incorporation within polymer chain

    Final product types

    • Engineering resins for electronic casings
    • Structural polymer blends requiring enhanced rigidity
    • Thermoplastic masterbatches for automotive applications

    4. Pigment Precursor in High-Stability Dye Synthesis

    Producers of organic pigments utilize 5-Dibenzosuberenone as a precursor in the synthesis of polycyclic aromatic dyes with improved lightfastness and thermal resistance. The compound reacts in coupling and condensation steps that produce chromophores tailored for specialty ink or coating formulations. Careful management of reaction parameters such as temperature and pH is necessary to prevent by-product formation and ensure purity aligned with colorimetric targets.

    Industry compliance standards

    • EN 71-3 Safety of Toys – migration of certain elements (relevant for pigment use in children’s products)
    • Directive 2004/42/EC – VOC limits for paint and coating formulations
    • ISO 787 General methods of test for pigments and extenders

    Typical usage ratio

    • Intermediate charge: 0.5–2.5 moles per batch, calculated from chromogenic group needs and overall pigment mass
    • Modified for desired hue density and process efficiency

    Downstream process integration

    • Introduced in the early coupling reaction for diaryl pigment synthesis
    • Filtered and purified prior to finishing in pigment milling or spray drying

    Final product types

    • High-stability organic pigments for plastics
    • Dyes for specialized inkjet printer inks
    • Decorative colorants in high-temperature coatings

    5. Functional Material Synthesis for Electronics

    Electronic component manufacturers employ 5-Dibenzosuberenone in the synthesis of organic functional materials used for sensing, light emission, and dielectric applications. The rigid aromatic backbone contributes to molecular planarity and electron mobility in organic electronic materials. Accurate process control is essential to achieve required electrical properties and ensure batch-to-batch specification consistency demanded by device integrators.

    Industry compliance standards

    • IPC-4101 for base materials in printed circuit boards
    • IEC 60454 for electrical insulation systems
    • RoHS Directive 2011/65/EU on hazardous substances in electrical equipment

    Typical usage ratio

    • 5-Dibenzosuberenone is specified at 1–8 mol% of the conductive monomer set, determined by device architecture and carrier mobility targets
    • Fine-tuned using device-level QCs such as IV curves and dielectric constant measurements

    Downstream process integration

    • Entered at the oligomerization stage for functional polymer backbone formation
    • Blending with auxiliary donors/acceptors before solution processing or vapor deposition

    Final product types

    • Organic light-emitting diode (OLED) materials
    • Conducting polymers for sensors
    • Specialty dielectrics for microelectronic capacitor films
    Free Quote

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    Certification & Compliance
    More Introduction

    Introducing 5-Dibenzosuberenone: A Reliable Workhorse for Organic Chemistry

    Our Commitment to Consistency in 5-Dibenzosuberenone Production

    At our factory, every batch of 5-Dibenzosuberenone reflects years of practical manufacturing experience and research. We have watched chemists struggle with inconsistency when sourcing this compound, so developing a robust, reliable process is not about buzzwords—it is about real-world performance, time after time. Since our facility synthesizes this ketone starting from clean, rigorously purified dibenzosuberane, we track and address subtle variations in intermediates, solvents, and atmospheric conditions. This attention to detail helps us maintain both purity and chemical yield batch after batch without sacrificing scale.

    The kettle operators and lab analysts in our shop have seen that minor flaws at any stage—wrong temperature ramp, stray micro-impurities—lead to significant headaches down the line for users. Light contamination impacts color and stability; off-target crystallization introduces practical headaches for everyone involved in the value chain. Our focus on process chemistry makes these problems less common, and we validate each lot using modern NMR, HPLC, and GC techniques. Actual hands-on trouble-shooting beats generic marketing every time.

    Understanding 5-Dibenzosuberenone and Its Specifications

    5-Dibenzosuberenone is not an exotic molecule, but it remains vital for many organic transformations. This pale yellow, crystalline solid is the backbone structure for synthetic intermediates in pharmaceuticals, ligands, and dye manufacturing. Our main product line targets a purity of over 98%, measured by HPLC and confirmed by NMR. We routinely monitor for residual solvents—particularly dichloromethane and toluene—since experienced bench chemists notice even slight traces during sensitive syntheses. The melting point (typically around 120-123°C for our latest lot) serves as a rough check, but we never treat it as the only metric. Full certificates of analysis record trace elements, as several customers in the catalyst and advanced dye sectors have flagged tiny amounts of iron, copper, or phosphorous as problematic downstream.

    Over the years, we have switched from glass-lined pots to stainless reactors and then to specialty alloys when scaling up, specifically to avoid any risk of batch-to-batch metal contamination. Using custom filtration protocols ensures reproducible crystal size, which in turn helps partners who value consistent dosing and particle handling. The actual experience of loading and unloading the product counts for as much as any data sheet. Any chemist who has tried to transfer a stubborn, staticky crystalline powder from drum to flask knows that “flowability” is not a roadside claim, it’s the difference between lost time and streamlined workflow.

    How Our 5-Dibenzosuberenone Gets Used in Industry

    This molecule finds its place chiefly in fine chemical synthesis, especially as a precursor. Several research groups and process teams tell us they prize it for the construction of helicenes, carbazole-containing compounds, and advanced dyes. In academic research, 5-Dibenzosuberenone lays the groundwork for new ligating agents and nonplanar aromatic scaffolds. Some companies also use it as a building block for certain pharmaceuticals, where its rigid, fused ring system brings the right blend of steric bulk and aromatic character. In the context of photochemistry and material science, it helps produce specialty frameworks for semiconductors and sensors. We supply kilo-lot and multi-tens of kilo scale because most buyers in this sector operate at modest throughputs, but need consistent quality over several years of project timelines.

    One case stands out—a partner working towards a proprietary photoactive dye for low-voltage display screens. A subtle impurity in a competitor’s lot caused unpredictable color shifts in their final product. Our batch, screened by both spectral purity and trace analytics, solved the problem. They came back for a tailored cut in moisture and particle size, showing how real-world use trumps broad technical claims in the end. We also work closely with pharma clients who need rock solid traceability for regulatory purposes, providing not just documentation but also the transparency to walk through our quality process line by line.

    How 5-Dibenzosuberenone Stacks Up Against Similar Compounds

    Many who approach our team for consultation ask why 5-Dibenzosuberenone should be chosen over other aromatic ketones. Professionals who have worked on benzosuberone, 9-fluorenone, and their analogs know that not all tricyclic ketones behave the same during functionalization. The suberenone core’s geometry introduces specific reactivity—adding bulk without flattening the molecule—making it less prone to over-reduction or unwanted rearrangements. In several oxidations, we have found that this molecule delivers smoother control than 9-fluorenone, which tends to form by-products or polymeric material more easily when reaction conditions wobble. When compared to dibenzosuberol derivatives, the ketone’s lower polarity gives it cleaner separations and simpler post-processing, especially when partners move on to form imines or hydrazones.

    A few of our larger industrial customers who invested in in-house pilot runs confirm the practical difference: yields on scale hold up, and the product behaves consistently during scale-down for test batches. We do not rely on generic specs here. Our technical support team pulls real samples from finished lots to support feasibility studies or troubleshooting, offering data on actual performance in end-use, not just raw numbers.

    Practical Considerations: Storage, Handling, and Shelf Stability

    Every kilo of 5-Dibenzosuberenone that leaves our plant travels in lined fiber or HDPE drums, sealed tightly to prevent contamination. Those who have faced clumping, product browning, or flaky texture from poorly handled lots know that real-world usability begins with packaging. On the factory floor, we store the crystalline solid away from direct sunlight and major heat sources. It will withstand reasonable humidity, but we always emphasize cold, dry storage for long-term stability. During hot summers, we’ve found even small shifts in warehouse air quality can affect flow properties, especially in high-purity material. Good house-keeping and frequent inspections pay off far more than automated protocols.

    End-users sometimes ask about shelf life. 5-Dibenzosuberenone stands up well to standard storage, typically retaining full activity and color for more than a year if kept sealed. Repeated opening and long exposure to humid air will cause gradual yellowing and surface clumping—hardly a disaster but still an annoyance during dosing. We encourage users to keep containers closed when not sampling, and to use dry scoops or spatulas. Routine re-testing is no hassle in our lab; open dialogue about aging effects matters more than generic warranty language.

    Our Quality Assurance and Analytical Practice

    Every batch we produce passes through an experienced QC team, not just automated machines. Our hands have handled enough in-spec and off-spec material to know that unexpected issues will crop up from time to time, especially in larger manufacturing runs. We run dual-lab verification using both classic and modern methods—NMR, HPLC, mass spec, and Karl Fischer water assays. Minor differences between lots are flagged and discussed, since some customers need the tightest reproducibility for regulated pharma or electronic materials work.

    A buyer recently called us about a faint aromatic impurity they detected with a high-end 700 MHz NMR machine. We immediately put parallel samples through intensive MS and GC analysis, tracked the issue to a vendor solvent anomaly, and reissued a replacement lot with openly posted data. No-nonsense, transparent troubleshooting keeps business relationships strong. This sort of rapid, honest response comes from years of running our own reactors, rather than jobbing out synthesis and repeating information from upstream suppliers.

    Meeting Challenges in Customization and Scale

    Production chemists rarely want the same specification for every process. Over the last decade, requests for alternative particle size distributions, tighter metal cutoffs, or different polymorphic forms have prompted us to continually adapt our purification and drying steps. It’s not enough to say a product is “customizable”—our workshop has proven workflow adjustments to match project needs. During one pilot run for a university, fine milling improved both solubility and filtration during imine formation. For another pharma partner, cutting trace sodium reduced side reactions in an autoclave hydrogenation step. Each tweak gets documented for repeatability, not just summarized in technical literature.

    Scaling up brings new hurdles in every specialty chemical operation. Heating uniformity becomes a practical problem, as larger vessels shift reaction times and can introduce local hot spots or micro-gradients that favor side pathways. Technicians in our plant have stood overnight to monitor temperature, adding in fresh solvent to prevent caramelization and off-odors that would otherwise end up in the shipped product. Running reactor calibration and monitoring agitator integrity at every fill pays off in long-term process reliability, not in brochure copy.

    Environmental Responsibility in the Chemical Industry

    Many in industry now want not only a reliable product, but also a cleaner, safer process. Over the last ten years, our plant has cut solvent waste by recycling bulk dichloromethane and reusing aqueous washes under controlled conditions. The team constantly reviews heavy metal inputs and seeks alternatives to avoid trace liability for users. Waste minimization is not just a buzzword for lab audits—having cleaned a dock spill or decontaminated an accidental discharge, our staff knows how much hassle environmental shortcuts can bring.

    For projects with partners in regulated markets, documenting every input and output has become part of our routine. Several long-term customers have asked for audit trails stretching back several years; because we run all core reactions in-house, we provide real documentation, not patchwork assembly from various vendors. Sustainable footprint matters more now than cost alone, especially as downstream users face stricter compliance for both REACH and regional standards. We work closely with local authorities and global partners to ensure that our synthesis meets evolving limits for emissions and waste, and routinely publish summaries of our annual audit results.

    Looking Forward: Collaboration and Ongoing Development

    No specialty chemical operation thrives on routine alone. New research in organocatalysis and non-linear syntheses continually raises the bar for supporting science and process flexibility. Feedback from end-users—academic, industrial, and in-between—drives every update in our in-house documentation, analytical practice, and supply chain reliability. Every year, we re-invest in laboratory scale-up, pilot studies, and raw material sourcing to keep improving both product quality and technical service.

    Some of our most valuable improvements have come from joint development projects with advanced materials startups and pharmaceutical R&D centers. By sitting down together, walking through laboratory notebooks, and testing new reaction conditions, we learn what modifications actually improve outcomes in daily production. Questions about unusual kinetics, stability under reactive gases, or long-term batch homogeneity meet practical answers directly from our in-plant team. If future needs point towards more refined specifications or niche application support, our manufacturing base is set up to adapt, document, and support the next steps for both new science and reliable supply.

    In Summary: Why Working Direct from Manufacturer Matters

    Trust in specialty chemicals builds not just on price or supply chain speed, but on a track record of problem solving and technical openness. Sourcing 5-Dibenzosuberenone directly from a manufacturer with both real experience and practical process control means receiving a material that fits into workflows without surprise, whether for research, pilot scale, or full industrial production. By building close links between synthesis, analytics, and end-user hands-on experience, we aim for outcomes that save both time and resources in every phase of a customer’s operation.