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HS Code |
843649 |
| Name | 5-Chloro-2-Nitrobenzamide |
| Cas Number | 2234-29-1 |
| Molecular Formula | C7H5ClN2O3 |
| Molecular Weight | 200.58 |
| Appearance | Yellow to orange powder |
| Melting Point | 181-184°C |
| Solubility | Slightly soluble in water |
| Purity | Typically ≥98% |
| Density | 1.61 g/cm³ |
| Synonyms | 5-Chloro-2-nitrobenzamide; 2-Nitro-5-chlorobenzamide |
| Smiles | C1=CC(=C(C=C1C(=O)N)[N+](=O)[O-])Cl |
| Inchi | InChI=1S/C7H5ClN2O3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H,(H2,9,11) |
| Storage Temperature | Store at room temperature |
| Application | Organic synthesis intermediate |
As an accredited 5-Chloro-2-Nitrobenzamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 25g package contains 5-Chloro-2-Nitrobenzamide, securely sealed in an amber glass bottle with a printed hazard label. |
| Shipping | 5-Chloro-2-Nitrobenzamide is shipped in tightly sealed containers, protected from light, moisture, and incompatible materials. Packaging complies with chemical safety regulations. The shipment is labeled as a hazardous substance and handled by certified carriers, ensuring safe transportation. Appropriate documentation, including safety data sheets (SDS), accompanies the shipment for regulatory compliance. |
| Storage | 5-Chloro-2-nitrobenzamide should be stored in a tightly sealed container, kept in a cool, dry, and well-ventilated area away from direct sunlight and incompatible substances such as strong oxidizing agents. Avoid moisture exposure. Proper chemical labeling and secondary containment are recommended. Store at room temperature unless otherwise specified by the supplier, and ensure access is restricted to trained personnel. |
Applications of 5-Chloro-2-Nitrobenzamide in Industrial Manufacturing5-Chloro-2-Nitrobenzamide serves as a critical intermediate in the synthesis and refinement of specialty chemicals. Our direct manufacturing expertise supports downstream industries with granular quality control and consistent performance in distinct industrial processes. The following application scenarios showcase how this raw material integrates into specialized sectors, focusing on real-world production requirements and regulatory standards. 1. Pharmaceutical Intermediate for Anti-Infective APIsPharmaceutical manufacturers incorporate this compound as an intermediate during the multi-step synthesis of certain anti-infective active pharmaceutical ingredients, particularly benzamide-based derivatives. Production protocols leverage its reactivity in targeted steps, which enables precise molecule construction within commercial-scale batch reactors. The downstream use requires meticulous documentation and full compliance with GMP for regulated markets. Industry compliance standards
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2. Agrochemical Synthesis: Fungicide Active Ingredient ManufactureOur material is used by agrochemical producers to build advanced aromatic cores for selected fungicide actives. The downstream formulation requires exact impurity control and reproducibility to meet registration and environmental safety requirements in both import and exporting jurisdictions. Industry compliance standards
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3. Colorant Precursor in Dye and Pigment ProductionSpecialized colorant manufacturers rely on this intermediate to construct chloro-nitro-substituted aromatic moieties for high-stability dyes and pigments. These colorants are destined for high-end textile and plastics applications, facing stringent migration and light-fastness requirements, as well as compliance testing for traces of residual process intermediates. Industry compliance standards
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4. Intermediate for Specialty Chemical CatalystsProducers of organometallic catalyst systems leverage this compound in the assembly of advanced ligand architectures. The raw material’s specific substitution pattern supports precise binding site modification, crucial for tuning selectivity and activity in polymerization and fine chemical manufacturing processes. Industry compliance standards
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5. Precursor in Pharmaceutical Impurity Profiling StandardsContract research and analytical labs use this substance to prepare certified reference materials for API impurity profiling. Sourcing directly from the manufacturer ensures full traceability and reproducibility for critical calibrations in regulated LC-MS and GC testing environments. Industry compliance standards
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Here we are in the business of making chemicals—hands-on, in-lab, and with genuine accountability for every batch. Day in, day out, precision matters as much as consistency. Our shop’s 5-Chloro-2-Nitrobenzamide reflects that. For buyers and researchers who want more than a datasheet, I’ll lay out what separates our material from the typical stuff you can find in a trader’s warehouse or a random bulk shipment. Years of tweaks, tight process control, and good manufacturing discipline shape each kilogram that leaves our floor.
Walk through our production lines and you’ll see why seasoned formulators come back for our product. The heart of the matter: control at every stage, from sourcing to synthesis to packing. We run closed systems that limit external contamination and use pure precursors, which gives tighter control over purity and trace impurities. Spec for our common model runs at a minimum 99% GC purity (by in-house verification). By pushing that standard, we keep research teams and downstream manufacturers from chasing ghosts in their reactions—real-world productivity rather than troubleshooting bad input.
There’s nothing generic about the stability profile either. Over countless batches, we’ve chased after photostability, shelflife, and hygroscopicity issues that early formulations exposed. Current bottlings remain free-flowing and unreactive, kept dry with controlled humidity packing. We also choose HDPE-lined drums and sealed polybags for every shipment—no secondhand sacks or risk of seep-through, which means low-volatility off-gassing in hot months, and no “mystery caking” even during transit to humid regions.
The folks who buy from us don’t all sit in university labs. We see 5-Chloro-2-Nitrobenzamide ending up in dye intermediates, pharmaceutical step-ups, active agro precursors, and analytical tools. In each pattern, precision matters. A synthetic chemist scaling an API starting block can’t afford phantom side products slipping into his batch. The dye plant technical lead wants color intensity without unpredictable byproduct hues. By sticking with strictly controlled precursors and batch-wise validation—including elemental analysis, water content assessment, and spectrographic scans—we keep that promise.
Our batches always test for trace metals and halide contamination. This rigor meets the demands of cGMP-adjacent sectors who can’t tolerate variable reactivity. The standard specs are checked against each lot, with full records stretching back years. The feedback loop of repeated use and new customer trials guides our improvement. You won’t be troubleshooting mystery spots or fogged NMRs here.
Spend enough years in this industry, you can spot the difference between a producer’s lot and a third-party repack. Simple visual checks show less dust, fewer fines, more consistent granular sizing on our product because we never let old, damped-out stock get reblended or “made good” by drying ovens. Production happens batch-to-order, keeping every lot traceable and fresh. The difference shows in less time pre-filtering and no “batch-to-batch jumpiness” in solubility or color gradation.
Other sources may tout high purity, but runaway thermal color or odor is common in poorly controlled manufacturing. We monitor every batch with in-house HPLC as well as third-party reference labs in the case of international shipments, so what shows up on the manifest matches what actually arrives. Less residue, less persistent yellowing, and no unexplained off-odors—that’s the net result of producing under strict in-house scrutiny, not just pulling from an unlabeled warehouse pile.
Technicians using our 5-Chloro-2-Nitrobenzamide never wonder if their powder will clump, track static, or throw off clogs in automated feeders. Granule sizing and flow character were refined after end users in tableting and blend lines reported their pain points. Actual solvents and temperatures used in the field drove our selection of drying curves and handling procedures, not theory from a textbook. That cuts down on formulation surprises and helps scale up from R&D to pilot to full run with confidence.
Every time we send a batch for pre-shipment check, we confirm moisture content and purity to keep consistency. Shelf stability runs confirm no drop-off in dissolution, so what’s freshly packed in the factory lands with the same qualities at the customer end. That comes from experience facing real-life shipping and storage environments, not just simulated warehouse conditions. Customers appreciate actually being able to use the chemicals as planned, without fussing over last-minute re-drying or re-filtering.
Our applications team gets asked every week about compatibility with large-scale pharmaceutical syntheses, custom coloring systems, and even regulatory registration support. Because we maker ourselves, our technical support can actually dig into process specifics: solvent recommendations, impurity control methods, and shelf stability in various packaging. Feedback often arrives in the form of “It arrived in the drum exactly as expected…and made it through our critical step without needing any workarounds.” Not every supplier can follow up with batch-level details from their own logs, but we do—real records from our own hands, not hearsay.
By tuning our product and workflow for compatibility with popular synthesis routes, we’ve helped both smaller innovation labs and larger manufacturers keep their runs predictable. Supplements such as detailed batch dossiers, impurity scans, and packing configuration options let customers make compliance and qualification routines quicker. Years of dealing with import rules, flags on sodium content, or nitro residue restrictions enable us to answer regulatory and end-user queries based on experience—not generic certificates.
5-Chloro-2-Nitrobenzamide fills an important spot in the world of downstream synthesis and advanced materials. Its structure lines up nicely for conversion into more complex organics. Real-world examples show this intermediate unlocking new chemical spaces, such as specialty agrochemical precursors where every impurity could trip a patent application. Other clients draw on its stability in color fastness applications, where trace metal or chloride levels change the outcome. By keeping the specs reliable, customers don’t have to recalibrate processes mid-contract.
Pharmaceutical intermediates often require fine-tuned batch characterization, not just from a cost standpoint but also liabilities around unknowns. By sticking to proven production procedures, we’ve helped developers keep their R&D teams focused on value-added chemistry, not rescue operations for suspect inputs. Even in advanced dye systems, batch consistency means a plant manager doesn’t waste time adjusting downstream filtration or reacting to unexpected by-products.
Our experience isn’t just about making powder—it’s about taking products from early concept to registered materials operating in complex, regulated supply chains. We listen to those on the line with regulatory questions, documentation requests, or detailed impurity queries. Production records trace every raw material, and each modification in the synthesis protocol gets logged for future runs. We’ve seen how small tweaks upstream help a batch sail through downstream regulatory trials.
Many times, a researcher on the customer side unlocks a new application or highlights a rare impurity trend. Our production documentation gives us a leg up in reproducing the right batch for follow-on work, because we record everything in exhaustive detail. It builds trust and enables a level of technical collaboration absent in sources that don’t control their own synthesis chain.
The demands placed on intermediates such as 5-Chloro-2-Nitrobenzamide are always moving. New formulations come up as industry shifts and regulatory pressure increases. In our facility, that means regular assessments—humble trial syntheses, stability checks, side-by-side application runs. We’ve built changes into the routine: if a customer needs a new sodium-free route or wants a different particle size for a new feeding system, the transition just means a few lines of paperwork and a pilot run, not months of contract negotiation.
Each new tweak in our procedure carries through to repeatable production, not just the test batch. Production logs remain open for customer review, and every large order gets feedback time between initial sample and main shipment. Sometimes it’s as simple as a shift supervisor catching a slight color drift, sometimes it’s catching a spike in byproducts from a precursor—either way, rapid adjustment keeps the customer’s process safe from surprises.
With so many actors in the chemical trade, true vertical producers are rare. We track back every drum to the exact synthesis run, and every input shipment—traceability that means you don’t get chemical roulette. In the event of a technical issue, you get our process data, not excuses. Our protocols stretch to repeatable impurity fingerprinting, load-to-load consistency, and the low level of residual solvents buyers look for in regulated work.
Working through challenges—be it sudden raw material price spikes, logistics fires, or new compliance standards—has honed our scene sense. It’s more than a high purity number on a sheet; it’s about making sure no batch leaves before it meets what’s printed on the spec. This is practice steered by real concerns from the field rather than marketing slogans.
Manufacturing for research and high-volume industry means learning alongside our users. We bring practical tips direct from our own handling experience. Storage away from sunlight and strong bases prevents unnecessary losses. Field reports from end users guide us to reinforce those instructions—not out of theory, but observation. End users encounter variations depending on climate, so we tune our packaging after seeing how the product comes out after weeks in warehouses half a world away. It’s that ground-level feedback loop shaping each improvement.
Our attention to quality has real-world safety consequences. We weed out suppliers who send irregular raw lots, monitor for new banned contaminants, and choose process routes that minimize volatile byproduct risk. Customers articulate where packaging, shelf life, or reactivity fall short in other materials; those reports become action items in our own protocols. We keep decision-making technical, transparent, and presentable in the form of batch and safety documentation. For clients needing audits or third-party validation, production floor walkthroughs and process transparency are standard—part of being a manufacturer, not a middleman.
No product stays the same forever—especially in an environment where buyers expect regulatory compliance, evolving technical standards, and real-world problem-solving. We emphasize continuous training for our crew, regular updates to synthetic routes, and digital tracking of every process step. Gaps found during regular customer QA cycles get fed back into future production. As new environmental standards and downstream applications emerge, we shift procedures before issues turn up in the field.
Some customers request lower halide profiles, others look for more rigorous solvent removal in final drying stages. We have adapted batchwise purification to accommodate increasingly sophisticated R&D requirements. Automated process monitoring, digital logs, and open-door policy for external audits make us nimble without sacrificing quality. Honest working relationships with clients—built over years, not quarters—give us early warning about new trends and shifting regulations.
Running a real chemical plant, you learn that every step counts. If our 5-Chloro-2-Nitrobenzamide did not meet expectations, clients would turn elsewhere, and word would travel fast. Real-world reliability makes the difference, not price games or generic paperwork. We keep our materials pure, our production honest, and our documentation open, so downstream processes run smoother and operators keep coming back. Ask around in quality-driven labs and manufacturing circles—trust in a producer’s word travels by reputation as much as anything printed on the label.
Each drum that leaves our site represents hundreds of small choices in technique, materials, and process control. Our ongoing mission is better product with fewer headaches in the field, tuned to match every batch’s needs and the future challenges of the industries we support. Feedback remains our best teacher, and our customer’s results our biggest reward.