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HS Code |
949980 |
| Cas Number | 68189-52-6 |
| Molecular Formula | C7H3BrClF3 |
| Molecular Weight | 259.45 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Purity | Typically ≥98% |
| Boiling Point | 173-175 °C |
| Melting Point | -19 °C |
| Density | 1.68 g/cm³ at 25 °C |
| Refractive Index | 1.515 |
| Flash Point | 73 °C (closed cup) |
| Solubility In Water | Insoluble |
| Synonyms | 3-Bromo-6-chlorobenzotrifluoride |
| Smiles | FC(F)(F)c1ccc(Br)cc1Cl |
| Ec Number | 614-656-6 |
| Storage Temperature | Store at room temperature |
As an accredited 5-Bromo-2-Chlorobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 500g amber glass bottle with a sealed cap, labeled "5-Bromo-2-Chlorobenzotrifluoride, CAS 261762-34-7, for laboratory use." |
| Shipping | 5-Bromo-2-Chlorobenzotrifluoride is shipped in tightly sealed containers, protected from moisture and light. It should be transported according to regulations for hazardous chemicals, ensuring proper labeling and documentation. Avoid exposure to extreme temperatures and handle with suitable protective measures. Comply with local and international shipping laws for chemicals. |
| Storage | 5-Bromo-2-Chlorobenzotrifluoride should be stored in a tightly closed, clearly labeled container in a cool, dry, and well-ventilated area away from sources of ignition, oxidizing agents, and direct sunlight. Store at room temperature, avoiding excess heat or moisture. Ensure proper chemical spill containment and restrict access to trained personnel. Use in a fume hood to minimize inhalation risk. |
Applications of 5-Bromo-2-Chlorobenzotrifluoride in Industrial ManufacturingAs the original manufacturer of 5-Bromo-2-Chlorobenzotrifluoride, we supply this halogenated aromatic intermediate for critical synthesis steps in several industrial sectors. This compound’s unique structure and reactivity make it a reliable choice in fine chemical manufacturing, with applications concentrated in advanced agrochemical synthesis, active pharmaceutical ingredient (API) production, specialized dye intermediates, and high-performance material precursors. Below we detail key application scenarios verified by established downstream industrial processes. 1. Selective Herbicide Synthesis5-Bromo-2-Chlorobenzotrifluoride provides an essential building block for synthesizing fluorinated aromatic rings in targeted herbicide molecules, including aryltriazolinones and phenoxy derivatives. Major crop protection formulators use this intermediate during multi-step condensation and cyclization reactions, ensuring high purity for subsequent transformations. Integration helps control harmful weeds without impacting non-target plant species through selective binding. Industry compliance standards
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2. API Intermediate for Antipsychotic AgentsPharmaceutical manufacturers employ 5-Bromo-2-Chlorobenzotrifluoride in the synthesis of halogenated diaryl precursors, which serve as intermediates for compounds in the benzisoxazole and benzamide drug classes. These reactions typically proceed via Grignard or lithiated intermediates, essential for maintaining regioselectivity during pharmaceutical-grade preparation to satisfy stringent regulatory audits. Industry compliance standards
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3. Fluorinated Benzene Dye IntermediatesThe compound’s unique trifluoromethyl-bromo-chloro arrangement enhances chromophore stability and lightfastness when utilized in the manufacture of high-performance dyes. Specialty dye producers introduce it into multi-step Friedel–Crafts reactions to construct complex diphenyl structures, ultimately supporting the color strength demands of industrial textile coloration and printing inks. Industry compliance standards
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4. Fluorinated Polymer and Coating Material PrecursorProducers of specialized fluoropolymers and protective coatings utilize 5-Bromo-2-Chlorobenzotrifluoride as a functional precursor in polymer modification and crosslinking reactions. Its incorporation imparts hydrolytic stability and enhanced surface characteristics, making it essential for engineering plastics used in electronics and anti-corrosion applications. Industry compliance standards
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5. Advanced Agrochemical Fungicide IntermediateThis material enters as a strategic halogen source in the synthesis of high-value triazole and strobilurin fungicides. Formulators rely on its chemical stability and functional group positioning to achieve efficient nucleophilic aromatic substitution, which helps downstream manufacturers develop actives with precise spectrum and improved bioavailability. Industry compliance standards
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Competitive 5-Bromo-2-Chlorobenzotrifluoride prices that fit your budget—flexible terms and customized quotes for every order.
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At our facility, 5-Bromo-2-Chlorobenzotrifluoride, referenced in production under model number BC-123F, has been part of daily life for over a decade. Our plant workers, managers, and engineers keep a close eye on the process—starting from raw materials to the drumming and storage of the finished product. There’s nothing abstract about it. For us, every batch counts, and so do the details that often slip through the cracks in glossy marketing sheets.
What we load into the reactors is a blend of halogenated aromatics. Our 5-Bromo-2-Chlorobenzotrifluoride rolls out clear, colorless to light-yellow liquid, depending on the cooling steps. It has a faint chemical aroma distinctive for this class of compounds. Dense storage containers are a must; anyone who has handled this will tell you how it settles heavily in drums, compared to lighter solvents. Packing and storage always follow rigorous checks for moisture, since even a touch of water—a result of sloppy pumping or ambient humidity—spells headaches for downstream synthesis.
In our workflow, purity levels go above 99 percent, using repeated fractional distillation and gas chromatography as our regular quality gate. We don’t deal in generic purity figures; technicians track impurities like dibromo or dichloro byproducts on every shift. Contaminants, as any chemist knows, will throw a wrench in the next reaction, whether we're supplying this to an agro intermediate facility or an API manufacturer.
We see 5-Bromo-2-Chlorobenzotrifluoride heading into a dozen sorts of plants, but our main clients come from the specialty chemical sector. Synthetic chemists in the pharmaceutical world use it as a cornerstone for assembling complicated aromatic compounds. Halogens at the 2 and 5 positions give this molecule unique reactivity—they open up coupling routes where single-halide compounds won’t perform. That selectivity keeps their processes efficient: fewer side products, tighter isomer control.
In crop protection, formulating companies demand this compound for active ingredients in herbicides and fungicides. The halogen pattern shapes the bioactivity profile—change those positions, and you get a different effect. We learned this first hand after years of fielding technical questions from lab managers, agronomists, and academic researchers who want to squeeze more yield from their hectares without raising residue levels in the soil.
Pigment production plants take our drums for colorant intermediates. These folks need consistency; fluctuations in melting point or trace impurities throw off their shade formulations. We have had our share of calls over barely-perceptible off-notes. One time, a pigment customer flagged a strange precipitation after using material pulled from a container stored close to their boiler room. Since then, we’ve insisted on unbroken cold chain for any supply going to high-end pigment plants.
Anyone in chemical manufacture knows the catalog is full of benzotrifluoride variants—each one with a small change in its substitution pattern. We worked with 4-Chloro-3-Bromobenzotrifluoride, 2-Bromo-4-Chlorobenzotrifluoride, and even the unsubstituted parent compound. Our laboratory trials and large-scale batch data show that small structural shifts change more than just reactivity—they impact boiling point, handling hazards, and storage stability. For example, 5-Bromo-2-Chlorobenzotrifluoride’s melting point and vapor pressure land right in the sweet spot for liquid reaction setups, particularly where easy phase separation is needed.
Certain clients start with simple chlorobenzotrifluoride, thinking to save on cost. Over time, they cycle back to our product—yields in downstream coupling are higher, and extra purification steps fall away. There’s no shortcut to this: changing a bromine for a chlorine position means the aryl ring becomes more responsive to palladium-catalyzed reactions that drive much of today’s fine chemical synthesis. The reliability in selectivity pays off at scale.
Even so, customers sometimes expect one variant to stand in for another, based on price sheets alone. Our technical sales team often needs to sit down with end users, reviewing reaction pathways step by step. We run pilot tests with their formulation teams, proving how slight changes in structure shift both yields and impurity profiles. This back-and-forth has shown over the years that real knowledge beats catalog numbers every time.
Factories producing 5-Bromo-2-Chlorobenzotrifluoride deal with tough chemistry. Every operator in our plant understands the risk. Halogenated aromatics need detailed PPE rules and well-rehearsed emergency planning. It’s not a substances for beginners; vapors are irritants, and accidental contact with skin causes issues if hoses leak or seals fail. Our operators know we don’t compromise on workspace airflow or liquid-waste handling. Each year, our team adjusts operating procedures based on field and lab input—if you find a better way to contain or clean up a spill, it becomes standard practice.
Environmental monitoring doesn’t happen only because policymakers demand it—it’s where we learn how to spot process losses or minor leaks as they happen. Our real-time sensors and canary tubes sit next to bulk tanks, capturing even low-grade emissions. If you’ve spent nights resetting vacuum lines because of minor pump-back problems, you know it’s always cheaper to catch an issue sooner rather than wait for the regulator’s audit.
Waste handling pushes our crew to innovate. Brominated and chlorinated byproducts build up fast if we relax distillation controls. Over years of trial and error, our team fine-tuned a multi-column distillation layout to keep mother liquor content low. Off-spec material gets contained and safely destroyed. We also recover reuse streams for less-sensitive industries, building a circular approach to production and improving resource efficiency.
Our internal standards never rest. Product runs for 5-Bromo-2-Chlorobenzotrifluoride are sampled at three points in the pipeline. Chromatographic analysis stands as the workhorse in our shop; every technician gets trained onsite, not by ticking boxes on paperwork, but by working through bad chromatograms until they can spot trace impurity peaks without prompting. That hands-on approach pays back in reliability.
Finer points like water content and acidity—hard to see in a casual inspection—matter a lot in scale-up. We discovered, after batches ruined by tiny traces, how key these metrics are to large reactors. Dropping acetic acid traces below 20 ppm cut off-gassing and foaming, which made end users happy and let us boost throughput. Later, we tackled organosilicon contamination, a problem that started with poorly cleaned glassware. Once our team shifted to PTFE-lined vessels, those issues dropped away.
Feedback loops with institutional customers shape how we design acceptance testing at our gate. We run split-sample checks with their labs on an annual basis. Each discrepancy leads to round-table analysis; we dig through operating logs, compare solvent sources, and don’t blame outside variables until we’ve tested the exact same samples in-house ourselves. This root-cause effort keeps everyone honest and avoids finger-pointing when something goes astray in a large campaign.
We’ve seen the industry landscape shift. Chromatographic detection sensitivity pushed us to refine our separation steps. The trend toward low-residue, high-selectivity intermediates forced a rethink on how deep we take our purification. During REACH and global compliance rollouts, continuous improvement became non-negotiable; annual retesting of legacy protocols caught issues the old baseline never noticed.
Sometimes a partner’s needs push us further. We once supplied a project where end-use registration in the EU required full disclosure of trace-level byproducts. That meant mapping every pathway, running small-scale simulation batches, and sending reference material to accredited labs across two continents. It took months, but now our tech team delivers impurity profiles for every batch, not just upon customer request, but as part of the shipping paperwork.
None of this happened in a vacuum. Industry partners gave us tips for solvent handling and advised on everything from sampling ports to temperature profiles. In turn, we shared data from long-run reactor trials, helping customers tweak their processes to accept a slightly broader purity envelope or to cut out a costly post-reaction scrub.
Down the road, changing environmental regulations and tighter end-use registration rules will shape how 5-Bromo-2-Chlorobenzotrifluoride gets made and transported. Our technical and regulatory staff track ongoing proposals and carry out risk assessments before they become mandates. This proactive stance saves costly adaptation later, a lesson we learned after early missteps with international shipping documentation.
Supply chain volatility makes a difference on the ground. Sourcing raw materials calls for steady negotiation; prices for halogen feedstocks swing on global realities. Where supply tightens, our process engineers explore alternate routes, qualifying suppliers for both consistency and regulatory standing. Our numbers show that an unexpected spike in raw material price—like the bromoarene crunch of 2021—can ripple through costs and disrupt production for downstream partners. By working closely with suppliers, setting up long-term agreements, and building buffer stocks, we cushion end users against shocks.
Waste stream management remains a long-term focus. Developing new disposal routes and recycling protocols for spent reaction mixtures isn't optional anymore. The drive for a circular economy, once only a talking point, now guides our investments in hardware and expertise. From solvent reclaimers to thermal oxidizer upgrades, our floor managers measure progress by the ton, not by abstract targets. Customer audits now look beyond standard compliance lists—they want physical proof of continuous improvements. Over the past years, we have cut waste per ton by nearly 30 percent, validating our work with third-party verification.
Several competitors treat technical support as an afterthought. We don’t send summary sheets with jargon-filled guidance. Each year, we receive dozens of calls from plant chemists and lab heads with real production problems—blocked lines, unexpected color changes, or reactivity shifts. We’ve built a cross-departmental response protocol: technical leads visit user sites, analyze failed or sub-par runs, and suggest practical changes in agitation, feed rates, or mode of addition.
We also keep pilot reactors available to simulate various user settings. For example, one customer working on a new agro-intermediate line faced recurring separation troubles. We duplicated their process on-site, provided samples taken at each step, and recreated their downstream problem. In the end, a minor change in carrier solvent—using a tested co-solvent with improved miscibility—resolved the issue, cutting both cycle times and waste.
We invite customer QC teams for joint testing runs. By giving them access to analytical tools and batch records, we ensure that our specs fit their real application needs—not just generic industry standards. In the past year, more than a hundred customer process techs visited our plant for joint problem-solving, and several new product applications stemmed directly from those collaborations.
Strict documentation and open communication form our backbone. Every product lot receives traceability paperwork describing ingredients, process steps, test results, and any batch-specific events. Longtime customers trust that we share the tough news—product delays, raw material contamination, or borderline test cases—without spin or hidden agendas. In an industry where timing is everything, clarity builds real relationships.
Product stewardship goes further than compliance. Our approach draws on a decade of practical lessons: if a challenge shows up on a customer site, we know that addressing the root cause fast—and transparently—matters more than ticking boxes on a checklist. Regulatory staff in our company liaise directly with customer safety teams, sharing learnings from incident reports and near-miss cases. In the rare case of recalls or rework, we provide replacement stock on priority, backed by evidence of both incident and resolution.
Constant training and skills development define our workforce. Operators rotate through lab and production roles, building both chemical know-how and practical troubleshooting talent. Hands-on training covers not just chemical handling, but tank cleaning, emergency drills, and quality checks. Over time, this turns a workforce into a community tied by shared standards and common purpose.
We manufacture 5-Bromo-2-Chlorobenzotrifluoride for real-world needs, not in a vacuum of abstract targets. The molecule finds use in pharmaceuticals, agrochemicals, pigments, and more. Each application challenges us to produce a material that holds up to the test—batch after batch, drum after drum. We welcome anyone in the field who values shared experience, proven consistency, and support that doesn’t end after shipment. Our team stands ready, drawing from years on the line, to meet evolving standards and build the next chapter together.