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5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One

    • Product Name 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One
    • Alias SJB2-043
    • Einecs 629-877-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    240370

    Chemical Name 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One
    Molecular Formula C17H11BrN2O
    Molecular Weight 355.19 g/mol
    Appearance Off-white to light yellow powder
    Solubility Slightly soluble in DMSO, methanol
    Purity Typically ≥98% (HPLC)
    Storage Conditions Store at 2-8°C, in a dry and dark place
    Synonyms No common synonyms available

    As an accredited 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

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    Application of 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One

    Applications of 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One in Industrial Manufacturing

    As a specialized manufacturer of 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One, we support diverse clients in advanced synthesis, leveraging this compound’s structure for efficient downstream transformations in high-value sectors. Below, we detail the compound’s integration into leading industrial segments—each grounded in established practice, with a focus on technical application parameters, quality frameworks, and product development protocols required by major manufacturers in each field.

    1. Pharmaceutical Intermediate Synthesis: Anti-Tumor Agents

    Research-driven pharmaceutical firms utilize the compound as a core intermediate for producing heterocyclic frameworks present in modern anti-cancer therapeutics. It serves as a tailored scaffold in Suzuki and Buchwald–Hartwig couplings, forming N-heterocycle motifs critical for kinase inhibition activity. Medicinal chemistry groups incorporate this intermediate at the mitotic inhibitor or kinase inhibitor scaffold-building step, enabling precise construction of target molecules with required pharmacophore orientation.

    Industry compliance standards

    • ICH Q7A Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • EU EMA Guideline on the Chemistry of Active Substances
    • US FDA 21 CFR Part 211: Current Good Manufacturing Practice
    • Chinese Pharmacopoeia (ChP) General Requirements for Intermediates

    Typical usage ratio

    • Used at 1–5 mol% relative to the target molecule; precise ratio adjusted based on transformation yield and structural complexity of final drug candidate.

    Downstream process integration

    • Enters multi-step synthesis as a coupling partner in palladium-catalyzed cross-coupling reactions, introduced before substitution, cyclization, or protection steps.

    Final product types

    • Pharmaceutical APIs for anti-tumor indications (e.g., kinase inhibitors, DNA intercalators)
    • Advanced clinical trial materials
    • Reference standard libraries for oncology R&D
    • Regulatory submission batches for IND/NDA filings

    2. Agrochemical Key Intermediate: Fungicide and Herbicide Synthesis

    Agro-science manufacturers incorporate the compound when synthesizing pyridine-containing fungicide and herbicide molecules, exploiting its electron-rich bromo-aryl core for regioselective functional group installation. It acts as a precursor for ring-closure or oxidative coupling steps in constructing bioactive crop protection agents, tailored to maximize target spectrum and environmental stability required by market-leading formulations.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 9001:2015 Quality Management in Agrochemical Manufacturing
    • OECD Principles of Good Laboratory Practice
    • REACH Registration where applicable

    Typical usage ratio

    • Incorporated at 0.8–3 wt% of overall synthesis charge, proportional to batch scale and target herbicidal efficacy post-derivatization.

    Downstream process integration

    • Reacted at early-to-mid stages of active ingredient production, typically in aromatic substitution routes, prior to thiol or alkoxy group introduction.

    Final product types

    • Crop fungicides targeting anthracnose, rust, and blight
    • Herbicide actives for broadleaf and grass control
    • Intermediate precursors for environmental impact studies
    • Formulated granules and suspension concentrates

    3. OLED Material Development: Hole Transport Layer Precursors

    Electronics and display original equipment manufacturers use this compound as a functionalized ligand or precursor for synthesizing organic materials in OLED devices. Strict control over substitution enables custom tailoring of triplet energy levels and hole transport characteristics, essential for high-purity emitter matrix formation in thin film deposition lines.

    Industry compliance standards

    • RoHS Directive (2011/65/EU) for restricting hazardous material usage
    • ISO 14001:2015 Environmental Management Systems
    • JEITA Standard EIAJ ED-4701/600 for chemical analysis in electronic components
    • Internal QC protocols for photophysical purity and batch homogeneity

    Typical usage ratio

    • Utilized at 2–10 mol% in ligand precursor charge, ratio fine-tuned to control energy transfer and emission wavelength of the final organic layer.

    Downstream process integration

    • Converted via C–N coupling or metal catalysis during the synthesis of advanced organic semiconductors, prior to vacuum deposition.

    Final product types

    • OLED emitter and hole transport materials
    • Evaporation-grade intermediate feedstock
    • Thin-film display prototypes
    • Commercial and prototype lighting modules

    4. Analytical Reagents: Chelating Agent Preparation

    Laboratory chemical suppliers and specialty reagent houses employ this compound in the targeted synthesis of chelating ligands for advanced metal ion detection and separation. Its di-pyridyl structure enables selective complexation, crucial for preparing next-generation reagents used in analytical testing protocols for environmental, pharmaceutical, and heavy metal analysis.

    Industry compliance standards

    • ISO/IEC 17025: Testing and Calibration Laboratories Accreditation
    • ASTM D1976–20 Standard Test Method for Elements in Water
    • USP General Chapter <231> Heavy Metals Testing
    • Purity verification to ACS Reagent Grade Standards

    Typical usage ratio

    • Batch incorporation at 0.5–1.5 wt%, adjusted according to target ligand structure and metal binding constant requirements.

    Downstream process integration

    • Involved in condensation or cyclation reactions of ligand synthesis, prior to salt formation or purification for final reagent packaging.

    Final product types

    • Complexometric titration reagents
    • Chromatographic stationary phase modifiers
    • Trace metal indicator kits
    • Sample preparation aids for ICP-OES and AAS

    5. Specialty Catalyst Ligand Manufacturing

    Catalyst producers integrate this compound into customized ligand libraries for homogeneous and heterogeneous catalysis, especially where controlled steric and electronic features lead to higher conversion rates in fine chemical synthesis or polymerization. Its unique bromo and pyridyl groups facilitate late-stage functionalization, forming bidentate or tridentate complexes with transition metal centers.

    Industry compliance standards

    • ISO 9001:2015 QMS for chemical catalyst production
    • OECD GLP for analytical traceability of catalyst batches
    • REACH pre-registration/safety data for industrial use
    • Material compatibility assessment for operational safety

    Typical usage ratio

    • Ligand component at 0.2–2 mol% in catalyst formulation; precise level dictated by transition metal species and end process conditions.

    Downstream process integration

    • Ligand synthesized from the compound via cross-coupling or ring-forming reactions, then coordinated with metal salt in final catalyst assembly step.

    Final product types

    • Palladium and platinum catalyst complexes
    • Fine chemical synthesis catalysts
    • Stereo-selective and enantioselective catalyst systems
    • Polymerization catalyst toolkits for research and scale-up

    6. Advanced Material R&D: Molecular Probe Construction

    Research institutes and innovative molecular diagnostics labs utilize this compound in the design of fluorescent or luminescent molecular probes, taking advantage of its structural features for attachment to diverse reporter groups. The ability to customize substitution patterns supports applications ranging from in vitro diagnostics to live cell imaging, depending on probe labeling requirements.

    Industry compliance standards

    • ISO 13485:2016 Medical Devices Quality Management (for diagnostic kit components)
    • USP Chapter <1225> Validation of Analytical Procedures
    • REACH/CLP regulations for handling research-use only (RUO) chemicals
    • Global harmonized system (GHS) classification for laboratory safety

    Typical usage ratio

    • Probe precursor at 0.3–2 wt%, proportional to fluoro-tag payload and target molecular weight in probe design.

    Downstream process integration

    • Integrated during probe backbone synthesis via C–C or C–N coupling, immediately before reporter group conjugation and final purification.

    Final product types

    • Fluorescent and luminescent molecular probes
    • Clinical diagnostic kit additives (RUO/LDT applications)
    • Bioimaging reagents for cell and tissue staining
    • Real-time PCR and in situ hybridization probes
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    Competitive 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One: A New Tool for Advanced Research

    A Reliable Choice for Skilled Chemists

    Working in a chemistry lab over the years, one gets used to digging through catalogs for molecules that bring real value to the table. Plenty of compounds promise results, but every so often, a newcomer gets research teams excited. 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One isn’t just another chemical on a shelf; it stands out for folks who regularly run synthesis experiments or dive deep into drug design studies.

    This compound carries the weight of a seasoned performer. Bearing a molecular formula that suits many synthetic challenges, it brings flexibility and well-documented reactions under a range of lab conditions. Chemists often look for reliability and predictable outcomes, tired of products that surprise in the wrong ways. My own projects benefited from compounds with similar brominated phenyl structures, especially when pathway selectivity mattered. The presence of bromine lets you attempt unique coupling reactions, and the rigid pyridyl rings support the kind of research that builds toward targeted molecules. It’s a much-needed improvement over less sophisticated analogs that bring inconsistency.

    Looking Beyond Simple Building Blocks

    Some compounds offer nothing more than a basic backbone. In contrast, 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One enables a deeper dive into novel functionalization, which makes it an asset for professionals seeking complexity with control. Traditional dipyridyls may carry their own strengths, but adding the bromo-phenyl group steps up the breadth of what can be achieved—think Suzuki, Heck, and Sonogashira reactions. I’ve been on teams where the difference between a plain pyridine and a well-substituted derivative changes the whole scope of a year-long research path.

    Among advanced researchers, the frustration with generic compounds often stems from uneven purity or inconsistent reactivity. This product brings tighter lots and well-cataloged crystalline forms. Anyone who has fished out impure or oily batches knows that a guaranteed melting point and reliable spectral data mean far fewer headaches. The testing data for this molecule hold up under scrutiny, setting it apart from many unbranded options populating bulk supplier lists.

    Meeting the Challenge of Cutting-Edge Synthesis

    Pharmaceutical development and modern organic synthesis demand chemical scaffolds that do more than just react—they have to do so with specificity. I remember a collaboration with a university group where tailoring ligand environments depended on careful control over ring-substituted pyridines. Generic versions failed our trials, but introducing a brominated version helped the reactions snap into place. 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One offers this targeted specificity, supporting exploration in organometallic studies and medicinal chemistry that reach beyond basic screening decks.

    Each element in its structure carries a role beyond simple connectivity. The bromine atom—less common than its chloro counterpart—unlocks routes that thrive under palladium-catalyzed conditions, and the dual pyridyl rings offer distinct opportunities in chelation or ligand design. Chemists who felt boxed in with other dipyridyl compounds gain more choice in synthetic plans, either extending molecular frameworks or building out new binding motifs in a deliberate, reproducible way.

    Where This Molecule Makes a Difference

    Application space stretches from academic to industrial contexts. Pharmaceutical labs use it to probe new therapeutic targets, leveraging both the reactivity of the bromide and the structure-directing abilities of the pyridines. I’ve watched computational teams model its properties and then hand synthesis teams materials that delivered those predictions, yielding better structure-activity relationships and ligand screens.

    Its value doesn’t end with pharma. In coordination chemistry, research teams have crafted robust metal-ligand complexes, often stumbling with less elaborate precursors. The design of 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One allows for tight, stable binding with a wide range of transition metals. I’ve seen it at the center of new catalyst studies, where its arrangement supports fine-tuning of electronic and steric profiles, something critical for developing better catalysts.

    Materials science also finds uses here. Past experience with similar molecules demonstrated that such compounds lend themselves to forming ordered assemblies, liquid crystals, or even sensor materials. It isn’t every day that a molecule meets the triple aim of reactivity, stability, and easy functionalization, but this one checks those boxes more consistently than the competition.

    What Sets 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One Apart?

    Difference matters most when practical work starts. Compared to simple dipyridyl ketones or unsubstituted varieties, this compound steps forward with an added dimension for C-C and C-N coupling. Classic alternatives often falter in multi-step syntheses or get bogged down by low solubility and bland reactivity profiles. Time and again, the team has come back to compounds like this one, where the bromo group opens paths for diverse transformations.

    Clean spectra and batch homogeneity also deserve mention. Many years of benchwork taught me there’s little point in sourcing a reagent that brings more mystery than predictability. This product offers robust NMR, LC/MS, and HPLC documentation, ensuring that results stand up during audit and review. I’ve seen academic investigators choose it to avoid surprise side products, a risk with bulk catalog chemicals riding on tenuous reputations. Quality control isn’t just a buzzword here—it gives real peace of mind during sensitive kinetic experiments or long-term storage.

    Trust Founded on Usability and Traceability

    User experience drives repeat selection, as every chemist knows. Handling is straightforward, and storage parameters follow well-established guidelines for aromatic compounds with halogenation. Over the years, I’ve seen less robust analogs degrade or react with ambient moisture, setting back projects by weeks. Regular users report high stability over months, a clear edge for anyone balancing multiple research timelines.

    Accurate labeling and transparent specification detail come standard, setting this product apart from generic listings filled with vague numbers. Regulatory documentation matches needs for import and customs, offering smooth procurement for global teams. The supporting paperwork is much more than a formality—anyone who’s struggled through audits or international transfers will value the ease it brings. From my perspective, working in labs with varying jurisdictional needs, this simple attention to detail lifted more administrative burdens than most realize.

    Safety: An Important Piece of the Puzzle

    Handling new compounds, especially those bearing halogens, reminds professionals to respect safety protocols. This molecule demonstrates solid performance in routine hazard screenings. I recall safety assessments on related compounds; attention focuses on minimizing exposure during weighing and transfer stages. Practical advice means glove use, fume hood handling, and careful labeling. The well-documented stability under standard lab atmospheres reduces surprises during use—an advantage for new team members still in training.

    Prepared protocols support safe spills and disposal. The documentation steers clear of legalese, opting for clear recommendations based on up-to-date hazard studies. Chemists, especially early-career researchers, benefit from this transparency. Too often, novel substances leave teams scrambling for information post-delivery. Here, the resources attached to the product reduce those uncertainties, making it a responsible fit in shared research spaces and strict compliance environments alike.

    Driving Advancements in Science

    Materials like 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One push boundaries in synthesis, catalysis, and ligand exploration, shaping how research moves forward. From supporting streamlined reaction mechanisms to unlocking new functionalization patterns, it brings possibilities that reach beyond standard fare. Over the past decade, my observations in both academic and contract research institutions reinforced the importance of having access to high-grade, unique scaffolds. Teams working with less distinctive analogs often rework protocols or settle for mediocre yields; this molecule closes that gap.

    Firms keen on securing intellectual property lean on new structures; a product like this opens the door for patentable derivatives and competitive process improvements. I’ve watched biotech startups and universities seize on such innovations, nurturing breakthroughs that stand out in the literature. By bridging core chemistry and applied science, the compound becomes more than a routine reagent—it shapes practical outcomes.

    Supporting Sustainable Chemistry

    Green chemistry figured prominently in recent years, and this compound lends itself to that discussion. Brominated aromatics sometimes invite concerns, but studies around its controlled reactivity favor efficient, low-waste pathways that align with modern standards. Vendors provide transparent sourcing records, so researchers can confirm origin and stewardship—a value add that resonates with sustainability-minded teams and auditors.

    I’ve noticed colleagues choose products backed by explanations of lifecycle and origin, and this one makes participation in “greener” chemistry more tangible. Supporting documentation highlights transport safety and end-of-life handling, so teams meet recycler and permit requirements with less paperwork chase. Knowing that compounds come documented from factory to benchtop has made my group’s conversations about grants, compliance, and public-facing communications much more productive.

    Collaborative Solutions: Getting More from the Molecule

    Modern chemistry thrives on collaboration. By focusing on reproducibility and robust data, the product supports teamwork spanning industry and universities. Published procedures reference it, bringing groups together in shared research goals, from rare disease therapies to novel polymer frameworks. Co-development efforts get a boost, as broader access and clear standards speed up project handoffs—my own projects benefited by reducing friction at every point.

    In my experience, smooth technology transfer demands more than just shipping a tub of material. Shared standards and open channels between supplier and researcher matter: timely technical answers, shared case studies, and updated protocols save months of troubleshooting. With 5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One, teams trading lessons across continents report high satisfaction, pointing to support that stretches beyond mere shipment.

    Potential for Growth: Looking Ahead

    As research accelerates in areas like energy storage, diagnostics, and pharmaceutical targeting, molecules with this level of design and documentation will anchor the next wave of discoveries. I foresee future lines of investigation building from this core structure—new ligands, probes, or asymmetric catalysts. Scientific growth demands building smarter starting points, and this compound stands well-positioned.

    Having worked through the unpredictable world of week-to-week research trials, I’ve learned that steady access to thoughtful, fully documented reagents often tips the odds of a successful result. This isn’t just a product—it’s a quality-of-life improvement for the scientists counting on dependable building blocks and credible technical support at every turn.

    Constructive Solutions for User Communities

    There’s room to make things even better. Further integration with digital lab assets, such as seamless spectral database support and batch tracking with real-time certificates, would unify research record-keeping. Greater openness in sharing user protocols and custom modifications grows the knowledge base and speeds method refinement for a wider audience. In the labs I managed, facilitating crowdsourced tips and workflow notes instantly raised team output and cut error rates.

    I also see value in amplifying direct scientist-to-scientist dialogue—building forums or user clubs focused on this family of compounds. By connecting practitioners, we could boost the pace of troubleshooting and offer examples of both solved challenges and failed attempts, turning mere suppliers into genuine research partners. That approach turns what used to be “just another reagent” into a platform for progress, broadening the range of projects and accelerating the time from idea to publication.

    Conclusion: A Compound That Moves Science Forward

    5-Bromo-1-Phenyl[2',3-Dipyridyl]-6(1H)One captures the advances researchers need in today’s demanding environment, delivering both practical performance and forward-looking flexibility. Professionals tackling complex synthesis, catalyst development, or new molecular assembly projects benefit not just from technical specs but from the real-world reliability and support that underpin every step. From my bench to yours, the value this molecule brings rests not only in structure, but in the trust and progress it supports, day in and day out.