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5-Bromo-1,2-Dimethyl-1H-Imidazolium

    • Product Name 5-Bromo-1,2-Dimethyl-1H-Imidazolium
    • Alias 5-Bromo-1,2-dimethylimidazolium
    • Einecs 821-754-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    455092

    Chemical Name 5-Bromo-1,2-Dimethyl-1H-Imidazolium
    Molecular Formula C5H8BrN2
    Molecular Weight 191.03 g/mol
    Cas Number 1385651-56-6
    Appearance White to off-white solid
    Solubility Soluble in water and polar organic solvents
    Inchi InChI=1S/C5H8BrN2/c1-4-7-3-5(6)8(4)2/h3H,1-2H3
    Smiles CC1=[N+](C=C(N1C)Br)
    Storage Conditions Store in a cool, dry place, tightly closed
    Purity Typically ≥98%
    Synonyms 5-Bromo-1,2-dimethylimidazolium

    As an accredited 5-Bromo-1,2-Dimethyl-1H-Imidazolium factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

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    Application of 5-Bromo-1,2-Dimethyl-1H-Imidazolium

    Applications of 5-Bromo-1,2-Dimethyl-1H-Imidazolium in Industrial Manufacturing

    As a primary manufacturer, we deliver 5-Bromo-1,2-Dimethyl-1H-Imidazolium with consistently controlled quality for its specific roles in several demanding industrial synthesis sectors. See below for major validated downstream application fields, each highlighting compliance, ratio, processing point, and real end-products in their respective chains.

    1. Pharmaceutical Intermediates for Antifungal Agents

    This compound serves as a key intermediate in synthesizing imidazole-based pharmaceutical APIs, notably antifungal actives. It undergoes nucleophilic substitution reactions to introduce bromoimidazolium moieties, enhancing biological activity. It is integrated mainly during advanced intermediate steps after initial scaffold construction, supporting efficient molecular customization for finished dosage forms.

    Industry compliance standards

    • Complies with ICH Q7 GMP for Active Pharmaceutical Ingredient Manufacturing
    • Referenced in United States Pharmacopeia (USP) for related process intermediates
    • Conforms to local Drug Master Files (DMF) registration practices
    • REACH registration for safe handling during synthesis

    Typical usage ratio

    • Applied at 0.9–1.2 molar equivalents relative to the primary backbone substrate
    • Ratio adjusted by reaction kinetics and target impurity control
    • Scale-up phases require pilot batch validation to confirm optimal charge
    • Micro-impurity threshold controlled below 0.5% (w/w) in batch outputs

    Downstream process integration

    • Charged during third or fourth stage of route, post-initial ring formation
    • Reaction proceeds under dry polar solvent at 40–60°C for substitution
    • Typically filtered and extracted post-reaction before downstream condensation steps
    • Quality control applied at intermediate isolation prior to final API synthesis

    Final product types

    • Oral antifungal tablets and capsules (e.g., imidazole derivatives)
    • Intravenous injection formulations for hospital use
    • Topical antifungal creams incorporating advanced imidazole actives
    • Veterinary pharmaceutical products for systemic fungal infections

    2. Advanced Materials Synthesis for Ionic Liquids

    Used in the manufacture of ionic liquids, this compound acts as an alkylating and functionalizing agent to produce stable imidazolium salts for electrochemical and catalytic material systems. Integration occurs at the salt formation phase, defining thermal stability and ionic conductivity in completed liquids or gels, driving performance in energy storage and specialized separation processes.

    Industry compliance standards

    • Adheres to RoHS and REACH for electronic materials
    • Material safety managed under ISO 9001:2015 documentation
    • Follows ASTM D7981 for ionic liquid quality assessment
    • No added SVHCs (Substances of Very High Concern) as regulated

    Typical usage ratio

    • Applied at 1.0 molar equivalent per final ionic liquid cation framework
    • Adjustment made based on targeted viscosity or conductivity range
    • Charge accuracy within ±2% for consistent batch-to-batch performance
    • Impurity control to <0.2% for high-purity energy sector requirements

    Downstream process integration

    • Enter alkylation sequence before final anion exchange
    • Performed under inert gas to prevent cross-reactivity in reactor vessel
    • Continuous stirred reactors used for yield enhancement in large scale
    • Product isolated by liquid-liquid extraction and vacuum drying

    Final product types

    • Ionic liquid electrolytes for lithium or sodium battery technologies
    • Solvents for metal ion separation processes in rare earth recovery
    • CO₂ capture solvents for green chemical processes
    • Electroplating bath additives targeting microelectronic finishing applications

    3. Agrochemical Synthesis Intermediate

    This material functions as a coupling or functional group modification agent during multi-step synthesis of certain systemic pesticide actives. It assists in ring closure or selective functionalization in the penultimate stages, providing controlled halogenation and improving derivative stability in crop protection formulations.

    Industry compliance standards

    • Manufacture under ISO 9001:2015 for agrochemical precursors
    • Conforms to FAO/WHO Specifications for pesticide raw materials
    • Handles all effluents according to EU Biocidal Products Regulation (BPR)
    • Referenced for technical-grade use in downstream EU REACH dossiers

    Typical usage ratio

    • Dosage from 0.8 to 1.1 molar equivalents to the precursor under mild basic or neutral pH
    • Precise charge controlled for minimizing hazardous byproduct formation
    • Lab optimization determines ratio before moving to kilo-lab or pilot scale
    • Batch reconciliation ensures <3% unreacted agent in downstream processing

    Downstream process integration

    • Added after initial alkyl backbone construction but before final methylation or sulfonation
    • Reacted in solvent blends selected for maximum yield and low impurity generation
    • In-process monitoring with chromatographic tracking of conversion
    • Followed by extraction, crystallization, and multiple filtration steps

    Final product types

    • Systemic fungicides for major crop protection applications
    • Broad-spectrum insecticide active ingredients
    • Seed treatment chemical actives
    • Plant growth regulator synthesis intermediates

    4. Specialty Chemical Manufacturing for Dye and Pigment Intermediates

    5-Bromo-1,2-Dimethyl-1H-Imidazolium provides reactive sites for selective halogenation and heterocycle introduction in advanced dye intermediate synthesis. It enables stepwise construction of chromophore precursors, improving reactivity and light fastness in the final pigment molecules for high-end technical coatings and printing ink industries.

    Industry compliance standards

    • EU REACH and CLP for chemical safety and labeling
    • ISO 14001 for environmental impact reduction in synthesis
    • Follows customer-specific QC for high-purity dye intermediates
    • Ensures zero content of restricted aromatic amines (EN 71-9)

    Typical usage ratio

    • Charged at 1.0–1.15 molar equivalents per reaction depending on degree of substitution required
    • Adjusted based on dye intensity and chromatic shift targets
    • Maintained within specification to prevent background shade issues
    • Residual halide levels controlled below 0.1% in finished intermediates

    Downstream process integration

    • Added during late-stage chromophore assembly prior to final coupling or sulfonation
    • Utilized in temperature-controlled reactors (50–80°C) for color consistency
    • Centrifugation applied post-reaction to isolate key intermediates
    • Purification by recrystallization before hand-off to end use ink or pigment divisions

    Final product types

    • High-performance printing ink dyes with advanced weather resistance
    • Solvent-soluble pigments for automotive and industrial coatings
    • Specialty colorants for electronics and photovoltaic panel encapsulants
    • Fluorescent markers and tracing inks for security printing applications
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    Certification & Compliance
    More Introduction

    Introducing 5-Bromo-1,2-Dimethyl-1H-Imidazolium: A Thoughtful Look at a Unique Chemical Compound

    A Chemical Solution for Modern Challenges

    Among the growing catalog of research chemicals, some compounds open new doors for lab-based discoveries and efficient synthesis. 5-Bromo-1,2-Dimethyl-1H-Imidazolium stands out in my experience as one of those reliable building blocks. Designed with two methyl groups attached to the imidazole ring and a bromine atom sitting in the five-position, this molecule’s structure packs more than just academic interest. In fact, each substitution delivers a distinct advantage in applications ranging from organic synthesis to materials science. Over the years, its precise molecular design has earned appreciation among chemists who seek cleaner reactions or improved yields.

    Practical Model and Specifications

    Researchers come to the lab hunting for reproducibility and practicality. 5-Bromo-1,2-Dimethyl-1H-Imidazolium answers this call with high purity and reliable behavior under typical reaction conditions. Most available samples arrive as white or off-white crystalline powder, easy to weigh and dissolve in common solvents. With a molecular weight falling around the mid-200s, the compound sits in a comfortable range—heavy enough for manageable handling, light enough to blend seamlessly with other reagents. Its bromine group offers a familiar reactivity for halogen exchange or cross-coupling, while the methyl groups prevent unwanted side reactions that can muddy results.

    One clear benefit in everyday lab use arises from the compound’s stability. Many similar heterocyclic salts begin to degrade or pick up moisture from the air. In contrast, this brominated imidazolium salt travels well, thwarts clumping, and stays true to form after weeks on the shelf—qualities I know matter when time is tight and accuracy counts. Trusted suppliers offer certificates of analysis showing purity above 98%, reassuring anyone who worries about impact from trace impurities.

    How Labs and Industry Put It to Work

    Modern synthetic pathways lean heavily on molecules built for speed, selectivity, and clean separation. 5-Bromo-1,2-Dimethyl-1H-Imidazolium serves as a foundation for work in pharmaceutical research, materials chemistry, and even advanced catalysis. If you’ve tried forming a C–C or C–N bond using traditional imidazolium salts, you know that stray byproducts can slow down purification and cut yield. The extra methyl group on the imidazole ring shields reactive sites—lessen those nasty side paths—and the bromine enables smooth downstream substitutions thanks to its predictable reactivity. I’ve seen it used to create room temperature ionic liquids for solvent-free processes, which matters a lot to labs sharpening their focus on sustainable chemistry.

    From my perspective, working with halogenated heterocycles should bring consistency, especially if you’re running pilot-scale reactions. 5-Bromo-1,2-Dimethyl-1H-Imidazolium manages to bridge the lab and the plant. Small-scale chemists can search for new ligands or intermediates, while industrial teams scale up with fewer batch-to-batch surprises. Over time, feedback from colleagues lets me know its melting point and solubility remain steady—no surprises during routine use.

    Distinct Features Compared to Related Compounds

    Every year, new imidazolium derivatives hit the catalog, but meaningful differences get lost in a sea of similar names. With this specific compound, the design sets it apart on two fronts. The bromine atom at the five-position isn’t just a tag for spectroscopists. It creates a launching pad for Suzuki coupling, leaving it more flexible than plain 1,2-dimethylimidazolium salts. Reactions that slow down using chlorine or iodine often pick up pace with bromine, striking a sweet spot between bond reactivity and manageable byproduct formation.

    I appreciate the methyl groups flanking the ring due to their stabilizing effect. Other imidazolium salts tend to react unpredictably, especially under basic or reducing conditions. Those added methyls keep the heterocycle intact, even during multi-step synthesis or long solvent extractions. Comparing side-by-side in a real lab run, the difference becomes clear: less decomposition, easier clean-up, and smaller chances of getting side-tracked by decomposition products.

    Importance in Research and Industry Today

    Working side by side with chemists struggling for reproducibility, I’ve found that overlooked details matter. Small differences in structure can change the course of a whole research program, sometimes saving weeks of troubleshooting. This compound’s robust nature and chemical selectivity have encouraged innovation, opened new synthetic strategies, and helped labs meet stricter green chemistry guidelines.

    For those in pharmaceutical development, having a compound able to create reliable building blocks matters. Imidazolium salts form skeletons for ionic liquids, drug intermediates, and polymer electrolytes. Recent studies in peer-reviewed journals highlight the benefits of brominated imidazolium-based ionic liquids in catalysis and extraction processes. These insights point toward future solutions in battery technology, recyclable solvents, or safer pharmaceuticals, all beginning from a simple core like 5-Bromo-1,2-Dimethyl-1H-Imidazolium.

    Quality and Transparency Supporting E-E-A-T Principles

    As an experienced writer and chemical researcher, I value products that come with clear documentation and robust batch analysis. 5-Bromo-1,2-Dimethyl-1H-Imidazolium earns trust through transparent quality data and consistent lab performance. Suppliers publish detailed NMR, IR, and purity certificates. Users can cross-check batch numbers or access synthetic history for each bottle, promoting safety and confidence. Within my own circles, these practices reduce experimental errors and help younger chemists spot red flags early, which strengthens skill-based learning.

    Education, experience, and a willingness to take responsibility for chemical handling all connect to quality compounds like this one. If a solvent impurity taints a reaction, months can vanish before the cause is found. Clear-cut labeling, batch recall practices, and transparent sourcing reassure both new graduate students and veteran researchers. In a time when science faces intense scrutiny, earning trust means more than fancy marketing—it’s grounded in sharing experience and facts. I encourage labs to choose compounds that offer this level of honesty and documentation.

    Real-World Experiences and Insights

    My years spent in academia and contract research labs have taught me to pay close attention to storage conditions, container seal integrity, and behavior in pilot studies. Some aromatic salts degrade faster than you’d think in high humidity; I’ve seen entire inventories go to waste for lack of airtight packaging or heedless benchwork. 5-Bromo-1,2-Dimethyl-1H-Imidazolium’s resilient profile makes it a practical choice for teams with varying infrastructure, from state-of-the-art facilities to budget-conscious departments eager for robust inventory.

    I remember one summer project aiming for a novel heteroaromatic ligand. Competing imidazolium salts proved frustrating: side products piled up, column chromatography felt like walking blindfolded, and the yield sagged after repeated attempts. Bringing in the bromo-dimethyl version changed the outcome entirely—simpler tracking under TLC, cleaner endpoints, and reproducible progress from week to week. Those small victories build good lab habits and teach new chemists that the right structural tweak offers a break from trial-and-error drudgery.

    Addressing Common Challenges

    Science marches forward, but old headaches endure: product degradation, operator error, and lackluster documentation. In my advising role, I always recommend choosing chemical reagents with proven track records and concrete supplier evidence. Shipments that arrive with clear synthesis logs and shipping temperature histories put everyone’s mind at ease. 5-Bromo-1,2-Dimethyl-1H-Imidazolium sits in the higher echelon for this, supported by growing demand for quality management systems in chemical supply.

    On the bench, I’ve noticed how easy it is to lose hours hunting for unknown contaminants after a bad run of a poorly characterized salt. Products that pass strict internal tests cut down on wasted solvents and allow for confident planning. Young scientists learn faster and publish more reliably, faculty avoid costly grant setbacks, and industrial projects move closer to commercial launch—all stemming from confidence in the chemical supply chain.

    Finding Solutions to Improve Outcomes

    Real advances in research come from strong foundations. Wide use of high-quality 5-Bromo-1,2-Dimethyl-1H-Imidazolium can address root causes behind experimental headaches. Here’s what makes the most difference: tighter collaboration between buyers and suppliers, investing in storage infrastructure, and emphasizing chemical literacy among newcomers. Suppliers who offer open access batch histories, real-time certification validation, and simple channels for technical questions help move this approach forward.

    Standing alongside colleagues at conferences or workshops, the consensus is clear: experienced users want side-by-side comparison charts, open feedback forums, and a place to share best practices. By encouraging a feedback loop, industry and academia can spot batch-to-batch anomalies before they spread, drive demand for tighter impurity standards, and help shape the next generation of brominated imidazolium salts.

    Innovative Applications and Future Directions

    As the chemical sciences branch into green chemistry, renewable energy, and precision healthcare, the value of adaptable and trustworthy reagents rises year after year. 5-Bromo-1,2-Dimethyl-1H-Imidazolium has already earned a place in studies focused on ionic liquid electrolytes for batteries, advanced catalyst design, and selective extraction techniques for rare earth metals. In each case, research teams highlight its selective reactivity and physical endurance under unusual solvent or temperature regimes.

    I see increasing crossover into fields such as advanced materials, where stability and functionality matter for high-performance coatings or sensors. With the right partnerships, this compound can become standard for reproducible advanced synthesis, saving groups the heartache of unexplained experimental failures. Keeping safety and traceability front and center, labs make bigger strides toward sustainable chemistry and scalable fabrication.

    Expertise You Can Trust

    Building real scientific progress requires more than test tubes and charts. It means weighing each reagent’s merits, learning from peer-reviewed successes and failures, and challenging suppliers to innovate. Years of hands-on experience plus input from trusted colleagues convince me that 5-Bromo-1,2-Dimethyl-1H-Imidazolium stands out—not as just another catalog addition, but as a chemical ally for projects demanding quality, reliability, and transparent sourcing.

    Looking ahead, the demand for clean, reproducible, and integratable compounds will only grow as regulations tighten and sustainability becomes a benchmark for any serious research group. Compounds like this shine brightest where attention to detail makes or breaks experimental goals, and users who value evidence, skill, and shared know-how set the bar higher for the entire industry.

    Closing Thoughts on Choosing the Right Chemical Partner

    Deciding what to put into your flask affects not just this experiment, but the next, and every set of results that follows. 5-Bromo-1,2-Dimethyl-1H-Imidazolium, through its careful design and proven history, offers a baseline of trust for both curious beginners and experienced professionals. Labs that prioritize careful selection over convenience end up with more reliable data, happier teams, and less stress come review time. As someone who’s sweated over many difficult syntheses, I can say the right choice in reagents always pays off in the long haul.

    Backed by clear documentation, consistent performance, and the positive verdict of both published studies and word-of-mouth peer networks, this compound makes a strong argument for quality over quantity. Whether you’re designing something brand new or scaling up for the pilot plant, investing in a robust, verifiable reagent like 5-Bromo-1,2-Dimethyl-1H-Imidazolium lays the groundwork for results you can stand behind, year after year.