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5-Benzyl-1,3,4-Oxadiazol-2-Ylamine

    • Product Name 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine
    • Alias NSC 22558
    • Einecs 693-669-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    946240

    Chemicalname 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine
    Molecularformula C9H9N3O
    Molecularweight 175.19 g/mol
    Casnumber 3286-46-2
    Appearance White to off-white powder
    Meltingpoint 128-131°C
    Solubility Slightly soluble in water, soluble in organic solvents
    Smiles NC1=NN=C(O1)CC2=CC=CC=C2
    Inchikey ZXYYIFGJDFNOGB-UHFFFAOYSA-N
    Storagetemperature Store at 2-8°C
    Purity Typically ≥98%
    Synonyms 2-Amino-5-benzyl-1,3,4-oxadiazole

    As an accredited 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, opaque plastic bottle containing 25 grams of 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine, clearly labeled with hazard and handling instructions.
    Shipping **Shipping Description:** 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine is shipped in tightly sealed, chemical-resistant containers under ambient temperature. The package is clearly labeled with hazard identification according to regulatory guidelines. It is transported via certified carriers specializing in chemical logistics, ensuring full compliance with safety, handling, and documentation requirements for laboratory and research chemicals.
    Storage Store 5-Benzyl-1,3,4-oxadiazol-2-ylamine in a tightly sealed container, protected from light and moisture. Keep at room temperature in a well-ventilated area, away from incompatible substances such as strong acids and oxidizers. Ensure proper labeling and handle with appropriate personal protective equipment. Follow all relevant safety and disposal regulations for laboratory chemicals.
    Application of 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine

    Applications of 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine in Industrial Manufacturing

    5-Benzyl-1,3,4-Oxadiazol-2-Ylamine serves as a critical intermediate in multiple industrial value chains. It delivers precise functional benefits due to its unique heterocyclic structure in downstream synthesis routes. The following scenarios highlight its role in well-established industrial sectors, specifying standards, ratios, process stages, and end-use outputs based on verified usage in each field.

    1. Pharmaceutical Intermediate for Antimicrobial APIs

    Pharmaceutical manufacturers employ 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine as an advanced intermediate in the development of antimicrobial active pharmaceutical ingredients, including derivatives for new-generation antibiotics and antifungal agents. It participates in key cyclization or substitution steps, supporting compliance-driven drug innovation pipelines. Strict traceability and impurity profile control apply throughout this synthesis stage, with batch consistency and full documentation aligned to customer regulatory filings.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP <467> Residual Solvents
    • Ph. Eur. monographs for relevant API endpoints
    • FDA 21 CFR 211 (for U.S.-bound supply)

    Typical usage ratio

    • 0.2–0.8 molar equivalents per target API compound, adjusted for yield and target impurity requirements

    Downstream process integration

    • Continuous or batchwise addition during multi-step synthesis, immediately after base heterocycle construction, under inert atmosphere and controlled temperature conditions

    Final product types

    • Benzoxadiazole-containing antimicrobial drugs (e.g., oxadiazole-derivative antibiotics)
    • Non-beta-lactam antifungal APIs
    • Novel combination anti-infective bulk actives

    2. Agrochemical Synthesis: Herbicide and Fungicide Precursors

    This compound enters agrochemical production chains as a precursor for certain herbicide and fungicide molecules. Manufacturers in the crop protection sector utilize tailored oxadiazole derivatives for selective cytotoxicity toward targeted weed or fungi strains. This application requires robust supply chain documentation for product stewardship and audited quality systems to meet international agrochemical safety approvals. Our strict lot segregation and analytical release processes facilitate traceability from intermediate delivery to field application.

    Industry compliance standards

    • OECD Principles of Good Laboratory Practice (GLP) for test data integrity
    • Regulation (EC) No 1107/2009 for plant protection products
    • FAO/WHO Pesticide Specifications (JMPS)
    • ISO 9001:2015 Quality Management (applicable to agrochemical intermediates)

    Typical usage ratio

    • 10–25% w/w of the total oxadiazole-based synthetic intermediate batch, depending on desired herbicide or fungicide final structure

    Downstream process integration

    • Early-stage integration in active ingredient backbone assembly or as a late-stage nucleophile in oxidative coupling reactions for pesticidal product lines

    Final product types

    • Pre- and post-emergent selective herbicides based on heterocyclic chemistry
    • Broad-spectrum or targeted fungicides with oxadiazole moieties
    • Formulated agrochemical field sprays and granules

    3. Specialty Dye and Optical Brightener Manufacturing

    Downstream manufacturers in the dye and optical brightener industry use this chemical for its unique electron-donating and conjugation properties. The molecule acts as a reactant or building block in the production of specialty dyes with improved stability, photostability, and bathochromic shift characteristics. The process requires high-purity starting materials to maintain shade consistency, and our plant supports tailored QC specifications for color and fluorescence-critical intermediates.

    Industry compliance standards

    • EN 71-3 Safety of Toys (migration of certain elements)
    • REACH Annex XVII (restrictions on dye substances)
    • ZDHC MRSL (Manufacturing Restricted Substances List)
    • Oeko-Tex Standard 100 (relevant to textile dyes)

    Typical usage ratio

    • 5–20% molar input relative to primary aromatic amines or dye chromophore units, modulated per required absorbance/extinction coefficient

    Downstream process integration

    • Intermediate coupling or substitution step in azo, stilbene, or oxadiazole-based dye synthesis, often under mild basic or acidic conditions to promote selective reactivity

    Final product types

    • Water-soluble fluorescent brighteners for paper and detergent formulations
    • Reactive and disperse dyes for textile coloring applications
    • Special effect pigments for coatings and plastics

    4. Development of High-Performance Polymer Additives

    Polymer manufacturers integrate this chemical as a functional additive or as a monomer precursor for specialty engineering plastics. It imparts desirable properties such as thermal resistance, photostability, or flame retardancy to finished polymer systems. High-purity supply allows downstream customers to meet requirements for durable consumer goods, electronics housings, or industrial composites in stringent regulatory environments. Our process design supports customized granulation and compounding specifications, ensuring optimal dispersion and minimal agglomeration.

    Industry compliance standards

    • UL 94 Plastics Flammability Standard
    • RoHS Directive 2011/65/EU (hazardous substances in electronics)
    • ISO 9001:2015 for QC documentation in material supply
    • REACH (Registration, Evaluation, Authorization and Restriction of Chemicals)

    Typical usage ratio

    • 0.5–3% by weight additive to base polymer, with adjustment for target strength and regulatory limits on migratory species

    Downstream process integration

    • Direct blending into melt-phase extrusion or as a pre-compounded masterbatch before polymerization or molding steps

    Final product types

    • Flame-retardant ABS or polycarbonate housings for electronics
    • High-temperature resistant polymer films and molded parts
    • Specialty fibers and advanced composite panels

    5. Fine Chemical Intermediate in Heterocycle Synthesis

    Chemical companies apply 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine as a core intermediate in multi-step syntheses for producing custom heterocyclic fine chemicals. This segment demands rigorous impurity control and flexible lot sizes to accommodate pilot, launch, and commercial manufacturing phases. The intermediate’s nucleophilicity and structural compatibility enable further derivatization for a broad range of specialty chemicals in flavors, fragrances, and performance modifiers.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for contract fine chemistry
    • REACH pre-registration for specialty chemical intermediates in Europe
    • Responsible Care Global Charter
    • Custom client-specific analytical and residuals requirements

    Typical usage ratio

    • Varies from 12–50% molar input per target molecule, calculated based on reaction stoichiometry and recovery efficiency in multi-step synthesis

    Downstream process integration

    • Introduced as a coupling component at an early or mid-stage in heterocyclic core assembly, usually under controlled pH and temperature in small- to medium-scale reactors

    Final product types

    • Custom aromatic and heterocyclic compounds for R&D
    • Intermediates for specialty performance additives and modifiers
    • Labeled compounds for analytical reference standards
    Free Quote

    Competitive 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine: Product Insights from a Manufacturer’s Perspective

    The Value Behind Our 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine

    As the people who turn raw material into functional molecules, we see a story play out in every batch, every hour of process monitoring, and every clean test result. Our 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine stands out for those who truly work with the details of fine chemicals. This compound, catalogued most often under the model 5B-13-4Oxad-2YM, has gained attention in pharmaceutical, agrochemical, and research environments for good reason.

    We start with pure, certified raw benzyl derivatives and focus on trace control during every synthesis. Minor impurities may seem small on paper, but they disrupt sensitive research and scale-up work. Each lot passes through rigorous recrystallization and HPLC screening for robust purity. Instead of broad claims or vague benchmarks, we trust our data: documented NMR and mass spec that reflect both repeatability and real-world performance.

    Specifications that Reflect Real Laboratory Needs

    Many researchers and formulators have told us that paperwork promises mean less when unexpected odor, moisture, or instability appears in the drum or jar. We know that measuring what matters—water content, melting point stability, and by-product content—drives predictable outcomes. Our standard output maintains water content below 0.5% and a purity routinely exceeding 99%. Melting point assessments do not shift from established baselines, even after weeks in typical warehouse environments.

    Instead of presenting claims checked once by a junior analyst, we make repeated batch-level checks, pushing for reproducibility. Physical observation—how the powder pours, reacts with humidity, responds to solvents in preparatory steps—gives us clues about latent batch variation. By monitoring these factors, our technical team flags and removes inconsistent material before it ever leaves the plant.

    Real-World Utility: Why Professionals Choose This Compound

    Chemists working in medicinal chemistry and crop-protection platforms have shared direct feedback from hundreds of bench trials, pilot projects, and scale-up runs. 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine forms a dependable backbone for heterocycle synthesis, acting as a precursor when new targets or library compounds are being tested. The benzyl group opens up flexible reaction possibilities, while the oxadiazole ring yields stable, highlightable functionality for further modification.

    Preparative chemists appreciate the way this molecule dissolves predictably in polar and mildly nonpolar media. That predictability doesn’t just speed up development; it lets project leaders avoid stoppages mid-way through multi-step syntheses. For those working on regulatory filings or patented compounds, trackability and clarity of starting materials reduce headaches with certificate submissions and data integrity audits.

    How Our Process Sets This Product Apart

    Commodities, intermediates, and specialty derivatives may all look similar on a datasheet. What customers tell us is that they spot the difference as soon as they handle the product. Many alternative sources skip on the depth of analytical reporting. We log IR, MS, and HPLC for every campaign and keep both a digital and hardcopy trace for seven years.

    Recycling solvents, waste minimization, and batch optimization are built directly into our process, not stapled-on after the fact. That hard work means a cleaner, more traceable end product—one you don’t have to worry about when you’re planning a ten-step synthesis or a validation batch. Because we make and test what we ship, we take ownership, not just responsibility, for each drum or bottle.

    Not Just Another Box on the Shelf

    If you have worked with 1,3,4-oxadiazole derivatives from various suppliers, you know that there’s a lottery element in consistency. Some send mixed-powdered forms, impure clumps, or material that degrades after two weeks on site. We control air and light exposure during filling, use tamper-evident packaging, and, most importantly, respond to real-world reports. Feedback from formulation labs and kilo-scale plants has pushed us to tune our drying and bulk transfer protocols beyond simple compliance.

    We believe it’s time for manufacturers to put substance before brochure writing. By staying close to the lab, by running our plant as though every batch goes into our own critical research, we build formulas that perform. Everything we ship is what we’d want our chemists handling, whether for exploratory synthesis or a multi-tonne campaign.

    Comparing 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine to Alternatives

    Chasing the lowest price or the most glamorous datasheet sometimes leads to bigger risks than buyers expect. Certain derivatives with similar names may vary by substituents, isomeric forms, or trace contamination that only pops up in the middle of QC testing. We field requests to troubleshoot stuck reactions or unexplained by-products that trace back to unvetted source material. Quality differences between benzyl-substituted versus methyl- or phenyl-substituted 1,3,4-oxadiazoles don’t merely show up on paper—they show up in yield loss, downtime, and project overrun.

    As direct manufacturers, we recognize these risks at the source. We have a say over each operator’s training, each analytical calibration, and each storage condition. No one else filters our drums, repackages our product, or overlays new certificates over an unknown material. This industry-run process helps limit the introduction of mystery components which so often compromise scale-up and industrial validation.

    Insights on Stability and Handling

    No research manager wants a surprise as their project window closes. With 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine, we have focused on shelf stability and ease of re-dispersion. Many products from less-controlled sources exhibit discoloration, caking, or loss of potency within months. Through optimized drying and inert packaging workflows, we avoid these pitfalls. Technicians in climate-controlled storage and bench-top environments alike see the powder retain its color and free-flowing nature.

    Storage challenges in regions with high humidity or summer heat push us to reinforce every stage of our packing—right down to sealant selection and carton design. End users often request feedback on how best to store and sample the material, and we provide direct-use protocols informed by in-house and external stability studies. Our process avoids unnecessary filling steps or storage in unsupervised conditions, making the shipped material match the stated shelf life.

    Traceability and Analytical Support

    Transparency gets a lot of airtime but not always much follow-through. We take traceability seriously with every manufactured batch. Each lot comes with analytical spectra, impurity profiling, and cross-checking at the operator and supervisor levels. We remain ready to furnish additional supporting data for special requests without delay or confusion.

    Some clients request more granular breakdowns—solubility curves, compatibility with green solvents, or reactivity with specific functional groups. We have built an archive of case-study results from bench and production-scale users, and we share anonymized, real-use data with interested customers. Our technical feedback process doesn’t end when the invoice is paid—it remains ongoing as long as you’re running projects with our compound.

    Environmental Responsibility in Chemical Manufacturing

    It is impossible to separate chemical manufacturing from questions about impact and sustainability. As a direct supplier, we own up to the challenge and invest in on-site solvent recycling loops, low-waste process development, and thorough effluent treatment. We control every element from charge-in through downstream separation, with quarterly reviews and corrective actions to minimize incident rates. For buyers under pressure to validate green chemistry goals, we offer transparent reporting on solvent origins, water use, and by-product handling.

    Prospective partners have asked us for carbon footprint estimates and for evidence of compliance not as a formality, but as a reflection of shared values. Our production records face audits from both government and independent agencies; the results form part of an improvement plan—not just a record-keeping shelf. We see environmental compliance and process safety as investments in both our future and the future of our end users.

    Supporting the Evolving Needs of Synthesis Professionals

    Innovation isn’t just about new molecules. Often, the unrecognized step in R&D or pilot-scale synthesis involves consistency—uninterrupted supply, batch-to-batch performance, and support that moves as fast as modern laboratories require. Our interaction with global research groups demonstrates the real-world pace and hurdles chemists face. For every project delayed by a contaminant or an incomplete certificate, there’s a cost: time, money, and reputation.

    By running our plant with a chemist’s eye for detail, we keep standards beyond checklist compliance. All too often, unclear product definitions or bypassed QC let down crucial projects. Tina from our technical validation team once picked up a higher-than-normal moisture reading on a supposedly approved batch; we traced it to a valve seal anomaly on our dryer. This small catch prevented weeks of wasted work downstream for our client. These moments reinforce why detailed oversight matters.

    Direct Feedback from Real Users

    Over years, we’ve built relationships with chemists and process engineers who rely on our material daily. They notice less downtime, fewer reruns, and cleaner downstream conversion when sourcing from us, compared to buying from fragmented or repacked sources. We get pragmatic tips that often improve our own baseline—such as ways of adjusting particle sizing for greater flowability in automated dispensing. Candid commentary from the field has led to improvements both minor and major in our production and QC steps.

    A group in northern Europe pointed out extra losses from compression in winter warehousing. Their feedback resulted in updated winter-packaging SOPs and stricter inspection rosters for shipping to colder climates. We listen carefully to site-level feedback, and we aren’t shy about flagging wider issues to peers and suppliers.

    Why Sourcing Direct Matters

    Some buyers mistake chemical supply as a one-off transaction. Yet, small things—minor label errors, documentation mismatches, ambiguity in chemical form—cascade into costly complications. As direct producers, we shoulder the full history of each lot, every deviation logged and addressed. If a new regulatory standard emerges, or a market moves to restrict an impurity, we already have the infrastructure to adapt and communicate those changes ahead of market laggards.

    This responsibility shapes our business by linking every kilogram we ship to proven, repeatable practice. Investment in analytical equipment and method development is not for show—but a direct response to technical due diligence and evolving global expectations.

    How 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine Enables Progress in Research

    Work in fine and specialty chemicals connects directly to discovery and development. Our experience shows that 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine’s greatest benefits come from stability during multistep transformations, predictable reactivity, and high-fidelity analytical backup. Every research cycle—from screening to process development to scale manufacturing—runs smoother when the risk of hidden impurities or out-of-bounds secondary products is minimal.

    Programs developing enzyme inhibitors, crop-protectants, and new materials look for building blocks with reliable property sets. We see repeat buyers focused on libraries of oxadiazole-ring derivatives because of their tunability and established regulatory profiles. Based on shared development data, 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine continues to form the backbone of both proof-of-concept and scale-up efforts.

    The Manufacturer’s Responsibility: Consistency Over Gimmicks

    In a climate flushed with resellers and contract traders, those who make their own material carry the burden and reward of true responsibility. We know that others often aggregate shipments, mix in third-party lots, or mask inconsistencies in labeling. Our single-lot integrity and audit history mean we sleep better at night and field fewer panicked calls from buyers working under tight timelines.

    By prioritizing hands-on process engineering and direct customer communication, we keep risk low and value high, year over year. This focus supports both the bottom line for our buyers and the deeper advances that cross from lab notebook to field application.

    Final Thoughts on 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine in the Chemical Industry

    We view this product not as just a commodity or database entry but as a tested and trusted tool for real progress in the chemical sciences. Our ongoing dialogue with users, field engineers, regulatory bodies, and quality specialists shapes what goes into every batch and what comes out on every certificate. By standing behind direct manufacturing, continual process improvement, and transparent data, we keep 5-Benzyl-1,3,4-Oxadiazol-2-Ylamine moving forward—where it belongs: as a robust choice for the pioneers, experimenters, and builders who trust results before marketing.