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5-Amino-2-Methylbenzoic Acid

    • Product Name 5-Amino-2-Methylbenzoic Acid
    • Alias 5-amino-o-toluic acid
    • Einecs 219-866-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    708138

    Productname 5-Amino-2-Methylbenzoic Acid
    Molecularformula C8H9NO2
    Molecularweight 151.17 g/mol
    Casnumber 2835-98-5
    Appearance Light yellow to brown crystalline powder
    Meltingpoint 176-179°C
    Solubility Slightly soluble in water, soluble in organic solvents
    Purity Typically ≥98%
    Density 1.28 g/cm3
    Synonyms 2-Methyl-5-aminobenzoic acid
    Smiles CC1=C(C=CC(=C1)N)C(=O)O
    Inchi InChI=1S/C8H9NO2/c1-5-3-2-4-6(9)7(5)8(10)11/h2-4H,9H2,1H3,(H,10,11)
    Storagetemperature Store at room temperature

    As an accredited 5-Amino-2-Methylbenzoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 5-Amino-2-Methylbenzoic Acid, 25g, is packaged in a sealed amber glass bottle with a secure screw cap and clear labeling.
    Shipping 5-Amino-2-Methylbenzoic Acid is shipped in tightly sealed containers, protected from moisture and light. Packaging complies with local and international regulations for chemical transport. It is labeled with proper hazard information, and transport is conducted via authorized carriers equipped for chemical substances, ensuring the compound's integrity and safety during transit.
    Storage 5-Amino-2-methylbenzoic acid should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizing agents. Protect from moisture and direct sunlight. Label the container clearly, and keep it in a designated chemical storage cabinet. Follow all relevant safety protocols and local regulations.
    Application of 5-Amino-2-Methylbenzoic Acid

    Applications of 5-Amino-2-Methylbenzoic Acid in Industrial Manufacturing

    5-Amino-2-Methylbenzoic Acid serves as a specialized intermediate in several industrial sectors that rely on regulated synthesis for value-added products. As the original manufacturer, we support downstream processors who require consistent quality and trace transparency in their formulations and production environments.

    1. Pharmaceutical Intermediate for Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

    This material provides a critical aromatic amine building block during the synthesis of certain NSAIDs. It supports multi-step processes leading to finished drug substances, where purity and isomeric integrity are required for pharmacological compliance and batch reproducibility. The intermediate typically enters the route via amide coupling, directly impacting impurity profiles and downstream cost efficiency. Customers apply it in a controlled GMP environment where thorough traceability and validated cleaning regimes are standard. Medicinal chemists select it for the customization of backbone modifications in APIs targeting pain relief and anti-inflammatory indications. Our tight QC protocols ensure that the product meets strict homogeneity, and our synthesis route yields minimal byproduct formation to streamline process validation.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF monographs (where applicable)
    • EU GMP Part II for chemical APIs
    • FDA 21 CFR Part 211 (for downstream finished pharmaceuticals)

    Typical usage ratio

    • Entry at 1.2–1.6 molar equivalents relative to the acid chloride or coupling agent, adjusted according to API target structure and efficiency of subsequent transformations.

    Downstream process integration

    • Introduced after initial aromatic nitration/reduction steps, preceding amide or ester coupling in API synthesis.
    • Mainly used for the preparation of intermediate amides before cyclization or side-chain introduction.

    Final product types

    • NSAID API bulk substances (e.g., specific derivatives for clinical pain management drugs)
    • Advanced pharmaceutical intermediates shipped for secondary synthesis

    2. Dye and Pigment Manufacturing (Azo Dye Sector)

    Processors in the pigment and dye sector utilize this compound for constructing diazo derivatives, enabling high-performance coloration in fibers and plastics. The presence of the amino and methyl groups enhances stability and shade intensity in azo dye formulations. Industrial users leverage its selective reactivity in diazotization and coupling steps, contributing to consistent batch-to-batch color outcomes. Large-scale dye manufacturers rely on continuous-feed synthesis lines with online impurity monitoring. This raw material is incorporated under controlled pH and temperature to maximize diazotization yields, supporting production where colorfastness and regulatory conformity are essential for export and downstream textile finishing certifications.

    Industry compliance standards

    • OEKO-TEX Standard 100 (for textile colorants)
    • REACH Annex XVII regulations (EU)
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals)
    • EN 71-3 (for toy pigment safety in Europe)

    Typical usage ratio

    • Applied at 0.5–1.5 molar equivalents in diazo coupling, depending on desired chromophore intensity and specific dye class.

    Downstream process integration

    • Added as a primary aromatic amine in diazotization before azo coupling with aromatic phenols or naphthols.
    • Integrated in continuous or batchwise reaction vessels with automated dosing for large-scale pigment manufacture.

    Final product types

    • Textile dyestuffs (cotton, polyamide, blended fabric dyes)
    • High-purity pigments for plastic and film coloration
    • Industrial printing ink concentrates

    3. Photographic Chemical Synthesis (Color Developer Intermediates)

    The compound features in the manufacture of key color-forming intermediates for photographic developers. Its structural motif allows for the finely tuned reactivity necessary in developer couplers, impacting image resolution and archival stability. Chemical plants exploit the methylated aromatic core to create developers that provide resistance against unwanted side-reactions such as fogging or cross-color contamination. Industrial QC teams monitor the intermediate’s input through HPLC and colorimetric assays to guarantee developer purity. Its integration into emulsified color developer preparation directly influences grain size management and photographic color reproduction—a crucial requirement for professional and archival imaging products.

    Industry compliance standards

    • ISO 18902: Imaging materials — Processed photographic films, plates, and papers — Filing enclosures
    • RoHS Directive 2011/65/EU for electrical photochemical components
    • REACH compliance for restricted aromatic amines
    • Specific in-house QC protocols from top-tier photographic film producers

    Typical usage ratio

    • 0.2–0.6 weight percent in developer formula, adjusted for layer thickness and specific emulsion type; direct input controlled by photographic image sensitivity requirements.

    Downstream process integration

    • Pre-mixed into developer coupler precursor solutions prior to dispersion into photographic emulsion layers.
    • Added before emulsification and coating procedures during roll or sheet film preparation.

    Final product types

    • Color photographic films (professional and consumer)
    • Color photographic papers for chemical printing
    • Archival imaging media

    4. Agrochemical Synthesis (Herbicide Intermediate)

    This amino benzoic acid derivative functions as a building block for selective herbicide synthesis, including compounds targeting post-emergent weed control. Its specific substitution pattern provides sites for further functionalization through chlorination and condensation. Agrochemical manufacturers require consistently low residual impurities and high assay value. Our material undergoes comprehensive QA that documents every batch for regulatory audit. Production engineers typically introduce it during the initial stage of multi-step herbicide synthesis, optimizing reaction pathways for both cost and downstream selectivity. The resulting intermediates undergo further processing before formulation into active herbicidal ingredients compatible with regulatory field application standards.

    Industry compliance standards

    • FAO and WHO specifications for technical-grade herbicide production
    • ISO 9001:2015 for process QA/QC
    • Globally Harmonized System (GHS) for chemical labeling and handling
    • EPA 40 CFR Part 158 (data requirements for pesticides, USA)

    Typical usage ratio

    • Employed at 5–15 weight percent of the starting material input for targeted herbicide active synthesis, with adjustments for desired selectivity and downstream conversion step efficiency.

    Downstream process integration

    • Used as an early intermediate in multi-stage reaction protocols (chlorination/condensation), prior to formation of final herbicidal actives.
    • Key substrate during heterocycle or amide linkage formation for selective herbicide classes.

    Final product types

    • Technical-grade herbicide actives (for further blending)
    • Customized herbicide intermediates for field trials and regulatory submission

    5. Performance Polymer Additives (Chain Stopper or Monomer Unit)

    Specialty polymer manufacturers incorporate this input as a chain-stopping and functional monomer to increase glass transition temperature and improve processability in high-performance resins. Its aromatic and amino groups offer unique sites for further cross-linking, enabling tailored mechanical and thermal profiles. QA teams utilize spectroscopic analysis to verify incorporation rates and impurity control. The upstream process may involve direct copolymerization or grafting, where this acid derivative limits molecular weight and provides functional end-groups compatible with epoxies and thermoset resins. Producers document all input lots for downstream compliance and warranty purposes, particularly for products used in automotive and electronics.

    Industry compliance standards

    • ISO 9001:2015 Quality management systems
    • UL 94 flame class (for polymer products in electronics)
    • RoHS for restricted substances in electrical polymers
    • REACH safety data registration (EU)

    Typical usage ratio

    • Acts at 0.5–2.5 mol% in chain-stopping applications; for functional monomer block, input rate depends on desired copolymer architecture and final physical property targets.

    Downstream process integration

    • Integrated during polymerization as a reactive comonomer or post-polymerization adduct.
    • Introduced at the prepolymer solution phase, allowing controlled chain termination or modification.

    Final product types

    • Specialty engineering plastics (for automotive, electronics)
    • Functionalized polymeric additives
    • Reactive resin intermediates for adhesives and coatings
    Free Quote

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    Certification & Compliance
    More Introduction

    5-Amino-2-Methylbenzoic Acid: Insights from the Manufacturer’s Floor

    Genuine Experience with 5-Amino-2-Methylbenzoic Acid Production

    Every batch of 5-Amino-2-Methylbenzoic Acid tells a story of precision and hands-on care. Inside the manufacturing plant, years of improvement and observation have strengthened the connection between raw material choices and the final purity of this compound. Working with sensitive aromatic amines and fine-tuned reaction conditions, the process depends heavily on small operational details that don’t always show up in the supplier paperwork.

    For us, quality isn’t a buzzword. It’s a direct outcome of careful filtration, consistent temperature control, and strict monitoring at each step. From sourcing high-purity starting benzoic acids, to batch reaction management, we have learned the effects of pressure changes, solvent quality, and aminating reagent control. Each step reflects intent, not routine. By turning knowledge into repeatable actions, we make sure the 5-Amino-2-Methylbenzoic Acid coming out of the dryer meets or beats the performance chemists have grown to depend on.

    The Model and Specifications: What Sets Our Material Apart

    Here, there’s no generic approach. The molecular structure (C8H9NO2) of 5-Amino-2-Methylbenzoic Acid provides a backbone that supports multiple reaction pathways. Our product features a consistent granular crystalline form, easy to transfer and dissolve, supporting use where precision dosing makes all the difference. Years of testing reveal that controlling the particle size not only reduces wastage in downstream processes, but also cuts down on unpredictable reaction byproducts. Repeated quality checks help keep impurities—especially regioisomeric or colored byproducts—out of the product stream. The team’s pride comes from impurity profiles that consistently meet expectations for uses across dye intermediates, pharmaceutical building blocks, and custom chemical syntheses.

    We maintain strict adherence to purity standards that matter at scale, measuring beyond the minimum specs. Analytical techniques like HPLC, FTIR, and melting point determination form the backbone of our in-house verification. Chemists working with our product regularly report minimal contamination from related aromatic amines. This direct feedback, combined with our own experience in handling process stresses, shapes every specification we set and every improvement we pursue.

    Where Chemists Use 5-Amino-2-Methylbenzoic Acid

    In practice, 5-Amino-2-Methylbenzoic Acid travels a long road from production line to finished product. Organic synthesis laboratories look for reliable intermediates with minimal side reactions—qualities this compound can offer if handled right at the source. The methyl and amino groups allow site-specific reactions, making this a favored starting point for engineers in the dye and pigment industries. The pharmaceutical sector trusts this molecule for its consistent structure in the synthesis of APIs, especially when building complex benzene ring derivatives is necessary. Each time someone orders a new batch, their feedback teaches us one more lesson about how 5-Amino-2-Methylbenzoic Acid performs across different chemical pathways.

    Compared to Similar Aromatic Amino Acids

    Manufacturers know that no two benzoic acid derivatives behave quite the same. Compared to isomers like 3-amino-2-methylbenzoic acid or the widely used 2-amino-5-methylbenzoic acid, our 5-Amino-2-Methylbenzoic Acid delivers better performance for certain coupling reactions. The specific position of the amino group reduces off-target substitution, boosting yield in some pharmaceutical syntheses and pigment applications. Over the years, process engineers share stories of downstream improvement after switching to our material—lower catalyst loads, less troublesome side products, and savings in both cleanup and raw material costs.

    Our team keeps a close watch on market samples and alternative sources. Sight and smell reveal much before reaching analytical instruments. Off-color batches or stubborn clumping in comparative products often point to storage or transport challenges outside the manufacturer’s control. By keeping all stages under our own roof and limiting product transfers, we see fewer lot-to-lot inconsistencies. Custom blending or specific cuts by traders often introduce variability that catches chemists off-guard. By going straight to the plant floor, professionals can eliminate those surprises.

    Production Challenges: What Matters Most from a Manufacturer’s Perspective

    One lesson learned over time—the tiniest details in reaction setup matter out of proportion to their apparent size. Variable humidity in the plant or a small drift in reagent supplier purity can ripple through and show up in batch behavior or final texture. Sometimes, water or oxygen contamination sneaks into the mix, and even after hundreds of cycles, every operator learns to trust their instincts as much as the digital readouts. Care in storage and transfer maintains the acid’s stability and preserves flow through subsequent processing steps. Each shipment that leaves our loading dock reflects input from a team deeply involved in the chemical’s lifecycle.

    Diligence at the crystallization phase means less rework and smoother dissolution in customer tanks. Control at this step also keeps byproducts—unwanted anilines or non-target methyl mixtures—down to undetectable levels. Through joint work with our partners, we sometimes custom-fit the process to a specific need: tailoring solubility for pilot projects, adjusting particle size for automated feeders, or developing lower-moisture grades where process uptimes demand it. Every tweak comes from real-world use cases, not abstract guidelines.

    Application Stories: Real-World Impact

    Clients in the dyes and pigments sector know downtime isn’t an option—missed deadlines or inconsistent color shades can have outsized consequences. Our technical service team fields questions about reactivity, solubility, and potential storage issues directly. Many years back, a prominent dye producer struggled with inconsistent batch turning points that stemmed from off-base methyl and amino positioning. By switching to our consistently pure 5-Amino-2-Methylbenzoic Acid, they stabilized downstream yields and improved color reproducibility; their feedback still shapes our quality control approach. Those stories, repeated across industries, underscore why close manufacturer-client contact always outperforms a chain of intermediaries. Nuances get translated into practical adjustments, not lost in paperwork.

    On the pharmaceutical side, small differences in intermediate purity can cascade into complex separation challenges several steps down the synthesis route. By understanding what their chemists see—sticky residues, odd colored filtrates, or delayed crystallization—our team identifies root causes back at the main reaction stage. Rather than rely on cloaked feedback, customers and plant teams regularly connect to investigate specific system behaviors. Only direct engagement drives lasting improvements; this cycle brings process learning full circle.

    Distinctiveness from a Manufacturer’s Lens

    Years of on-the-floor learning teach that not all marketed 5-Amino-2-Methylbenzoic Acid comes with the same reliability. Process ownership from raw material sourcing to the final packed drum matters in avoiding unnecessary risk. We see distinct differences compared to products from fragmented supply chains where resellers blend or repack intermediates. Wide variations in particle texture, unidentified foreign particles, and even subtle odor shifts usually result from gaps in production traceability. Customers voice preferences for full disclosure over rebranded product lines—they know ambiguity increases troubleshooting time and potential regulatory risk.

    Instead of leaving details to chance, full control gives us the confidence to certify each delivery’s consistency. Chemists appreciate not facing new impurity profiles with every reorder, and production engineers can keep approval times short without last-minute surprises. Every operator in our plant handles the product as though it’ll land in a highly sensitive pharmaceutical synthesis, keeping focus sharp and accountability personal.

    The Value of Tight Process Control

    Sophisticated end-users examine trace impurity data before bringing a new lot into critical manufacturing streams. We push hard to keep residual aminobenzoic acid isomers and unwanted methylbenzoic side compounds below industry detection limits, especially as HPLC and NMR characterization become more routine. Tight batch-to-batch reproducibility frees up resources in our clients’ laboratories, reducing overhead in process validation and regulatory documentation cycles. Clean, well-characterized intermediates are worth more than their market price when they let research and production teams focus on their innovation, not unpredictable clean-up or side reactions.

    Our in-house training standards, developed over decades, anchor every improvement we make. Tools evolve—more digital temperature controls, improved vacuum lines, and better filtration media—but what remains is a team’s intuition about how the product should look, smell, and behave. In the end, that hands-on knowledge anchors product quality, not just certificate numbers.

    Industry Changes and the Manufacturer’s Response

    Client needs change as regulatory standards tighten and as end markets adjust their requirements for traceability, safety, and environmental impact. The continuous drive from pigment and pharma clients for lower residual solvents and fewer unknown side products has shifted our investments toward analytical upgrades and facility improvements. Each change brings its own learning curve—training operators on new analytical software takes effort, but the transparency and trust it brings between manufacturer and chemist justifies every hour spent. Compliance with evolving standards isn’t an isolated task; it links directly into everything from raw materials to shipping documentation.

    As supply chains grow more complex, knowing your source—the actual people making the material—matters more than ever. Issues like cross-contamination in repacked drums, batch mixing after long transit, or “blending-down” to meet minimal specification happen too frequently when the product passes through multiple hands. By cutting out unnecessary intermediaries, we insulate our clients from these headaches and accelerate problem-solving.

    Potential Solutions to Industry-Wide Issues

    Production challenges don’t end with the final batch. Common industry challenges include off-site repacking, long maritime transport under uncontrolled conditions, and inconsistent documentation. Direct supply relationships with end users reduce these risks. On our side, batch traceability and a robust internal quality documentation system provide easy access to lot histories and real-time production data. Faster issue identification translates directly to higher batch acceptance rates in client facilities. This approach leads our industry peers to request shared best practices—demonstrating that everyone stands to gain from tighter transparency and deeper process alignment.

    Responsiveness also comes from ongoing partnerships. Our team offers technical support around application-specific concerns, such as managing recrystallization protocols or catching minor process upsets before they impact end-use. By keeping these channels open, we help engineers and chemists cut cycle times and reduce the resource drain of troubleshooting. Every direct phone call or site visit delivers more value than weeks waiting for answers down a distant supply chain.

    Supporting sustainable practices is taking greater priority every year. We have invested in waste minimization at each reaction step, using closed-loop solvent systems and energy-conscious temperature cycling to reduce impact. Where possible, solvent recovery and re-use bring concrete energy savings and environmental gains. Clients deeply value tangible evidence of this effort, as it connects directly to their own reporting goals and sustainability commitments.

    Looking Ahead: Direct Engagement Drives Progress

    The relationship between 5-Amino-2-Methylbenzoic Acid manufacturers and end users thrives on openness and long-term vision. Combining detailed analytical support with real plant experience builds trust rapidly—chemists want to see the fingerprints of manufacturing decisions in the lot they receive, not just words on a spec sheet. Direct feedback loops speed up improvements, making sure new needs or changed process parameters show up immediately in production adjustments.

    Our experience suggests that most application challenges result as much from communication breakdown as raw material limitations. By sending our team to visit partner plants, or inviting chemists to observe our production, we cut through uncertainty and speed up mutual understanding. This hands-on approach leads to fewer downstream surprises and better performance for everyone involved.

    The path from raw materials to finished 5-Amino-2-Methylbenzoic Acid reflects not only chemical expertise but a mindset. Every improvement and every batch emerges from close observation, open dialogue, and a willingness to learn from both success and setback. The real difference shows itself in processes that serve customer projects without interruption, letting innovation drive new product possibilities. In a changing world, that level of dependability stands out, batch after batch.