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5,5-Dimethylhydantoin

    • Product Name 5,5-Dimethylhydantoin
    • Alias DMH
    • Einecs 202-735-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    125225

    Chemical Name 5,5-Dimethylhydantoin
    Synonyms NDM Hydantoin, N,N-Dimethylhydantoin
    Molecular Formula C5H8N2O2
    Molecular Weight 128.13 g/mol
    Cas Number 77-71-4
    Appearance White crystalline powder
    Melting Point 174-178°C
    Boiling Point Decomposes before boiling
    Solubility In Water Moderately soluble
    Density 1.17 g/cm3
    Flash Point Non-flammable
    Pka 8.94
    Odor Odorless

    As an accredited 5,5-Dimethylhydantoin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A white, sealed 500g plastic bottle labeled "5,5-Dimethylhydantoin," featuring hazard symbols, chemical details, and manufacturer information.
    Shipping 5,5-Dimethylhydantoin is shipped in tightly sealed containers, usually plastic or fiber drums, to protect from moisture and contamination. It should be stored and transported in a cool, dry, and well-ventilated area, away from incompatible substances. Proper labeling and adherence to relevant shipping regulations and safety guidelines are required.
    Storage 5,5-Dimethylhydantoin should be stored in a tightly closed container, in a cool, dry, well-ventilated area, away from incompatible substances such as strong oxidizers. Protect it from moisture and sources of ignition. Properly label the storage container and ensure it is kept out of direct sunlight. Follow all relevant safety and handling guidelines as detailed in the material safety data sheet (MSDS).
    Application of 5,5-Dimethylhydantoin

    Applications of 5,5-Dimethylhydantoin in Industrial Manufacturing

    5,5-Dimethylhydantoin (DMH) supports several high-volume industrial sectors through its chemical stability and reactivity profile. As a raw material producer, we supply DMH for critical applications demanding tight process control, product traceability, and regulatory compliance.

    1. Water Disinfection Bromine Compounds (BCDMH Synthesis)

    DMH serves as the key substrate in producing 1-bromo-3-chloro-5,5-dimethylhydantoin (BCDMH), which is widely used as a slow-release bromine sanitizer for municipal, industrial, and recreational water treatment. The bromination process relies on the precise selection and purity of DMH to control active halogen output, ensuring consistent sanitizer performance and compliance with disinfection byproduct regulations. Major manufacturers require high-purity DMH to achieve strict cost-efficiency and product stabilization in tablet or granular forms.

    Industry compliance standards

    • NSF/ANSI Standard 60 (Drinking Water Treatment Chemicals – Health Effects)
    • US EPA guidelines for disinfection byproducts (DBPs)
    • EN 12975 (Chemicals Used for Treatment of Water Intended for Human Consumption)
    • SGS/ISO 9001:2015 certified QC systems

    Typical usage ratio

    • DMH content: 34-36% w/w of total BCDMH output; stoichiometry adjusted by targeted active halogen delivery and batch size
    • Ratio modifiable for solid or granular product formulations

    Downstream process integration

    • Bromination reaction with chlorine and bromine agents under controlled pH and temperature
    • Filtration and drying to correct moisture and particle size
    • Direct compaction or tableting for stabilized BCDMH products

    Final product types

    • BCDMH tablets and granules
    • Pool and spa sanitizers
    • Municipal drinking water disinfectants
    • Cooling tower microbicides

    2. Biocidal Hydantoin Derivatives for Industrial Cleaning

    In the industrial cleaning sector, DMH acts as a precursor for hydantoin-based biocides employed in surface disinfection and biofilm control. The production process demands well-defined DMH purity to optimize derivative yield and prevent off-target reactions during halogenation or alkylation steps. Manufactures of hospital and food processing sanitizers rely on validated DMH supply for reproducible antimicrobial spectrum and regulatory validation.

    Industry compliance standards

    • BPR (EU Biocidal Products Regulation 528/2012)
    • US EPA Pesticide Registration (FIFRA)
    • REACH (EC 1907/2006) for hazardous substances
    • ISO 22716:2007 (GMP for industrial cleaners)

    Typical usage ratio

    • Hydantoin core: 20-40% by mass of formulated biocidal concentrate
    • Loading level determined by downstream required kill spectrum and regulatory limits

    Downstream process integration

    • Introduced at halogenation stage for controlled substitution
    • Blending with carriers and stabilizers under low-moisture conditions
    • Post-reactor filtration to remove residuals and byproducts

    Final product types

    • Surface disinfectant fluids and wipes
    • Biofilm control agents for pipework and food preparation areas
    • Antimicrobial sprays and foams
    • Industrial hard surface cleaners

    3. Photographic and Imaging Chemical Intermediates

    DMH is an essential building block for stabilizers and nucleating agents in specialty photographic materials production. The material enters imaging chemical synthesis, where its controlled reactivity is crucial for forming developers and stabilizers used in film processing. Manufacturers use high-purity DMH to ensure that process residues and breakdown products do not impair photosensitivity or image fidelity.

    Industry compliance standards

    • ISO 18902:2013 (Imaging materials – Processed films and plates – Storage practices)
    • RoHS Directive (2011/65/EU) for hazardous impurities
    • REACH Annex XVII (Restrictions on manufacture and use of certain substances)
    • Internal photochemical QC and traceability audits

    Typical usage ratio

    • 5-12% DMH of total photochemical batch mass for developer and stabilizer intermediates
    • Customized by image contrast and grain retention requirements

    Downstream process integration

    • Direct charge to reaction vessel during developer or stabilizer synthesis
    • Purification by solvent extraction and crystallization
    • Addition to final emulsion blend prior to coating

    Final product types

    • Film and paper developer concentrates
    • Photographic stabilizer additives
    • Imaging chemical kits for x-ray and traditional film
    • Archival processing chemicals

    4. Resin and Polymer Stabilizers

    DMH is employed as a UV stabilizer and antioxidant precursor in the formulation of high-performance plastics and resins. Polyolefin and polyurethane manufacturers use DMH-derived additives to extend material lifespan and color retention by limiting free-radical-mediated degradation. Careful dose control is needed to avoid adverse reactions during resin polymerization and extrusion processes.

    Industry compliance standards

    • FDA 21 CFR 177.1520 (polyolefin resins in food contact)
    • ISO 4892-2:2013 (Plastics – Methods of exposure to laboratory light sources)
    • EC No. 1907/2006 (REACH safety and use restrictions)
    • UL 94 (Plastic flame retardancy, for stabilizer compatibility)

    Typical usage ratio

    • 0.05-0.4% DMH equivalent by polymer mass
    • Selection and dose defined by required UV resistance and thermal stability of the end product

    Downstream process integration

    • Direct blending with resin pellets during extrusion or compounding
    • Melt processing under inert gas to prevent unwanted oxidation
    • Post-process QC for leaching and stabilization efficiency

    Final product types

    • Outdoor polyolefin films
    • Automotive interior polymers
    • PU-based construction and insulation materials
    • UV-stabilized consumer plastics

    5. Veterinary and Animal Health Disinfectant Manufacture

    DMH derivatives form the active base of broad-spectrum disinfectants formulated for livestock premises, hatcheries, and animal transport vehicles. Regulatory regimes enforce strict thresholds on residue persistence and animal safety. Veterinary biocide producers require consistent DMH supply to meet disinfection efficacy while passing acute toxicity and residue risk assessments in finished formulations.

    Industry compliance standards

    • OIE Terrestrial Code (disinfectant use for animal health)
    • European Medicines Agency (EMA) MRLs (Maximum Residue Limits) for livestock areas
    • Veterinary Medicines Directorate (UK) standards
    • ISO 9001:2015 certified manufacturing protocols

    Typical usage ratio

    • 15-30% DMH-based active ingredient in biocidal concentrate
    • Adjusted by species, area size, and disease risk management plan

    Downstream process integration

    • Halogenation of DMH for controlled-release active formulation
    • Microbiological challenge testing on formulation batches
    • Bottling and dilution calibration for end-user safety

    Final product types

    • Livestock barn and poultry house surface disinfectants
    • Veterinary transport vehicle sanitizers
    • Farm biosecurity cleaning agents
    • Equipment disinfectant sprays

    6. Pharmaceutical Intermediate for Antiseptics

    In pharmaceutical manufacturing, DMH is used as the starting structure in synthesizing antiseptic and antimicrobial agents for topical medicinal products. GMP-certified plants demand narrow batch-to-batch purity and documentation for upstream DMH to support regulatory submission and pharmacopoeial listing. Process engineers use DMH for precise heterocycle scaffolding in synthesis routes targeting cutaneous and wound care formulations.

    Industry compliance standards

    • USP/NF Monographs (United States Pharmacopeia/National Formulary)
    • 21 CFR Part 211 (CGMP for Finished Pharmaceuticals – US FDA)
    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • EDQM CEP certification for intermediate supply chain

    Typical usage ratio

    • 8-18% DMH of synthesis batch (intermediate step), varying by antiseptic type and impurity controls
    • Ratio adjusted based on synthesis yield and target antimicrobial loading

    Downstream process integration

    • Introduced as core scaffold in multi-step synthesis pathway
    • Refined by repeated crystallization and filtration
    • Conversion and purification to final active pharmaceutical substance

    Final product types

    • Topical skin antiseptics
    • Cutaneous antimicrobial ointments
    • Hospital wound cleansing gels
    • Specialty biocidal creams
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    Certification & Compliance
    More Introduction

    5,5-Dimethylhydantoin: Reliability Built from the Reactor Up

    Product Introduction & Manufacturer Commitment

    For decades, we have run reactors and filtered crystals for chemistries that others considered too delicate or niche for consistent commercial manufacturing. Experience in each batch’s quirks – from feedstock quality to drying conditions – has shaped our approach to every specialty molecule, yet few compounds are as central to our daily output as 5,5-Dimethylhydantoin. We produce this organic intermediate at industrial scale, carefully controlling each reaction variable to yield a consistent, high-purity product stream. Our staff, many of whom have worked the same lines for years, know how to recognize the right hue, the proper granulation, and the behavior of the mother liquor to troubleshoot on the fly long before the analysts confirm a batch result.

    In practical terms, 5,5-Dimethylhydantoin comes off the line as a white crystalline powder with a distinct mild odor and low hygroscopicity. Our standard model meets a minimum purity of 99%, measured directly by gas chromatography rather than relying only on melting point or visual checks. We pack the material in double-layered sacks within steel drums on request, targeting customers for whom integrity through shipping is not negotiable. No shrinkage, no clumping, minimal static - each of these issues has been dissected in our production meetings ever since old hands noticed minor shipment complaints that we resolved years ago with new linings and better off-loading.

    Consistency is more than just raw assay numbers. Standard particle size range sets apart our chemical from mass-market or hobbyist blends. We dry and mill batches to balance fluidity for industrial processes against dust formation – a matter of worker safety and clean endpoints. If shipment distances require different moisture levels, we adjust on the fly, exchanging notes with logistics teams so end-users face no surprises.

    Behind the Formula: Molecular Stability and Process Predictability

    Molecular structure carries the real value in the plant. 5,5-Dimethylhydantoin, with two methyl groups at the fifth position, demonstrates resilience through high-temperature synthesis and downstream applications. The compound's robustness comes out during chlorination, bromination, and other halogenations that customers demand of their intermediates. Dissolution rates, boiling points, and thermal stability all underpin the reliability that formulators and blenders expect on an industrial scale. Each drum we send out, whether destined for a pool additive factory or a specialty textile finishing house, traces origins to a process refined through real-world production feedback, not just bench chemistry.

    Our focus on controlling impurities isn't an academic affair. Unreacted urea, trace ammonia, and sub-percent levels of off-spec isomers show up quickly in downstream chlorine engines and water purification devices, where even minor contaminants can catalyze unwanted side reactions or lower yields. We built closed-loop process controls, reengineered mother liquor recycling, and extended residence time in critical reactors. It took months of experimentation—not hands-off bench assumptions—to consistently drop impurity levels below industry benchmarks. Every improvement we made came with a learning curve, often at overtime and expense, but these lessons now mark the backbone of our reliability promise.

    Application Knowledge Earned in Practice

    Synthetic routes in our plant have been optimized through feedback from electroplaters, resin manufacturers, and water treatment engineers who care more about reaction efficiency and byproduct avoidance than about fancy buzzwords. For example, in resins and plastics, 5,5-Dimethylhydantoin often acts as a precursor for N-halamine chemistries, where its unique substitution pattern supports stable halogen bonding. Some producers tried lower-cost, less pure alternatives, but wound up with unstable batches, regulatory headaches, or frequent line stoppages. Over time, the market circled back toward manufacturers who could guarantee traceability and minimal batch-to-batch variation.

    In the realm of water disinfection, the core value comes from certainty. Big pools, closed-loop cooling systems, and municipal water test the product’s solubility, storage profile, and compatibility with physical system components. With competitors, floating fines or undissolved chunks can gum up feeders or settle out in critical piping. These “minor” annoyances cause outages, wasted time, and recurring maintenance calls. Our tailored drying and sieving infrastructure prevents these headaches. Recurring conversations with on-site plant technicians shape every equipment upgrade we deploy.

    As for agricultural use, our 5,5-Dimethylhydantoin supports formulations for slow-release biocides and crop treatment films. Our team has seen firsthand how varying the crystalline structure changes blending efficiency in extrusion and coating lines. Several years back, we responded to a midsized agchem client’s request to reformulate for improved processability — collaborating over weeks via video calls and site samples, we iterated the crystal habit to keep the process dust-free and the product uniform across small and large-scale equipment. Nothing beats visits to customer lines to see the true effects of each chemistries’ quirks.

    Comparing 5,5-Dimethylhydantoin to Related Intermediates

    Because every process engineer or formulator juggles both cost and performance, we often field questions about why one would choose 5,5-Dimethylhydantoin over its close molecular cousins. Much of the industry still leans on the parent hydantoin — an older staple — for simple reactions. But those with demanding applications notice the advantage provided by the dimethyl substitutions. Compared to unsubstituted hydantoin, the dimethylated variant handles more aggressive process conditions. It avoids caking in storage, offers greater chemical specificity in chlorination, and remains less sensitive to humidity swings in most climates. The methyl groups shield reactive sites, making the molecule less susceptible to undesired side reactions in applications that run strong oxidizers or acids. Years of scaled production have shown us that customers get up to 30% longer product shelf life and see an improvement in product retention during tough shipments, especially through tropical regions.

    Other intermediates like 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) derive directly from 5,5-Dimethylhydantoin through halogenation. While DCDMH offers rapid release in certain disinfection settings, its upstream stability and process cost hinge heavily on the quality of the base 5,5-Dimethylhydantoin. We learned early on that supplying these downstream derivatives means mastering the core hydantoin's synthesis first. Several competitors struggled to control reaction exotherms or ended with inconsistent, off-colored lots when rushing their cycle times. We built heat exchange and control systems for slow, steady throughput—an investment that paid off in reorders and lower customer complaint rates.

    For those choosing between 5,5-Dimethylhydantoin and similar cyclic ureas or imides, workflow compatibility guides most purchasing decisions. Most alternate compounds either lack the specific reactivity needed for N-halamine formation, exhibit solubility issues with commercial salts, or degrade too quickly under UV irradiation. Having investigated dozens of comparative side-by-side batch runs across industry lines, our technical teams saw that the dimethyl substitution strikes the best balance between reactivity and environmental endurance.

    Switching Suppliers or Upgrading Process Inputs

    For buyers weighing a switch from a competing supplier or planning an upgrade from older material, the main worry always lands on transition headaches. Our transition teams have worked with every major process line configuration in our key markets, and we document not just the product characteristics but real-world outcomes on each line. Case after case, we see that friction points pop up not because of gross purity differences, but because minor variances in drying, blend uniformity, and side product levels interact with the quirks of specific customers’ feed systems. We offer pilot batch samplings, on-site troubleshooting visits, and joint analysis sessions precisely because a bag with the same name can cause radically different outcomes depending on milling protocol, moisture adjustment, and packaging. This tight feedback loop has helped systematize our root-cause analysis so transitions are smooth and long-term reliability is achieved.

    Volume scaling presents a different set of challenges. New users with ambitions to move from kilo to ton lots often underestimate the scale effects on product handling and storage. Our bulk buyers solve these issues with shipping support, real-time monitoring of transport conditions, and warehouse guidance so integrity of the chemical is preserved from tank to dosing system. Larger volumes require more than just price breaks; they demand reliable documentation, predictable cycle times, and technical service that addresses everyday operating realities rather than just laboratory targets. Our records show that customers scaling with us see lower annual waste and avoid most headaches associated with dust control or spoilage during humid spells.

    Technical Challenges and Solutions on the Manufacturing Floor

    From the first drum off a new reactor to the thousandth ton over a fiscal year, manufacturing 5,5-Dimethylhydantoin challenges both equipment design and operator skill. Each batch starts as a simple solution, but subtle shifts change the entire outcome: feedstock purity, reagent ratio, even room temperature at mixing. Small deviations create large differences down the line—slightly high residual urea, for example, gums up drying belt screens and slows throughput. We address these at the source, opting for in-line spectrometers and ramping up controls after analyzing historic root-cause data. Every time a minor plug or slow dry slows a shipment, it triggers a post-mortem so we fine-tune setpoints or swap out media.

    Dust management requires hands-on innovation. Hydantoins, left untreated, tend to create powdery fines that provoke inhalation complaints or cause caking in feeders. We invested in modular filtering and dust containment at every stage, not simply to comply with occupational safety requirements but to cut raw loss and boost worker comfort. Over the last 10 years, we built a record of meeting local and international benchmarks by pursuing granular improvements batch by batch: real dry room airflow data, new vacuum lines, and batch-specific sieve mesh sizes.

    Solvent recovery, water management, and waste abatement represent major environmental and cost constraints. Through collaboration with green chemistry consultants and our on-site engineers, we designed solvent loops that cut hazardous effluent loads and lowered the energy footprint of main reactors. Recaptured mother liquor gets reprocessed, not dumped; solid effluent is stabilized for shipment to certified handlers. These efforts lowered our waste factor by over 20% last year alone. Sustainable production isn't just a press release for us—it's audited and documented at every campaign start and end.

    Testing, Traceability, and Client Partnership

    Every lot of 5,5-Dimethylhydantoin runs through our analytics lab before shipping. Beyond purity, we capture spectrometry fingerprints, particle size distributions, and microbiological assessment when shipment requirements warrant. We learned early that traceability assures not only regulatory compliance but continuous quality for client manufacturing lines. If a client picks up even the subtlest change—say a new supplier for ammonia or a plant water pH fluctuation—we can trace product back to raw input lots and shipping batches, often before the issue impacts finished products in the field.

    This commitment has earned long-term supply contracts. It's not just about hitting numbers on a spreadsheet but about ensuring that a sealed drum from our site behaves as anticipated, every time, wherever it lands. Every few months, client engineers and regulatory auditors tour our facility to check data, walk the actual line, and witness our batch tracking firsthand. Our open-door approach means they see the same trends and challenges we do. Recent audits have aligned our batch documentation with global requirements, easing cross-border documentation for customers expanding internationally.

    Our technical team offers ongoing field support, joining virtual troubleshooting meetings or traveling to customer sites to address line-specific challenges. Cooperation does more than buffer problems; it steers next-generation process improvements on both sides of the supply chain. Joint trial projects, from resin modification runs to field deployment in new water treatment configurations, have improved outcomes for clients and driven small but measurable shifts in our production priorities.

    Navigating Regulatory, Storage, and Transport Realities

    5,5-Dimethylhydantoin generally retains temperature resistance and chemical stability through most transport networks, but storage best practices still matter. Manufacturers in tropical or humid zones saw an uptick in moisture-related clumping until we collaborated with them on packaging tweaks and warehouse ventilation advice. Before rolling out improved liners and container sealing, we saw up to a third of overseas complaints stem from preventable condition issues—a statistic we have since driven nearly to zero. Where regulation demands specific paperwork or trace contaminants data, our documentation exceeds both local authorities’ checklists and major global standards.

    Handling safety isn’t left to chance. With every shipment, we supply detailed instructions based on locally sourced hazard data, constantly updating them to track new guidance from regulators and industry groups. Our in-house logistics team stays in close contact with carriers and distributors to minimize risk from transit damage or delay. Every aspect of storage and shipping dovetails with real experience: from warehouse fork operations to end-user hand transfer, we've seen virtually every way things can go wrong, and we've mitigated or solved each scenario through a mix of design and on-the-ground training.

    Looking Forward: Reliability, Real-World Application, and Product Development

    We see the global push toward greener chemicals and traceability moving steadily through water, textile, and plastics production. Our leadership team reviews supply chain resilience not once a year, but every quarter, benchmarking our 5,5-Dimethylhydantoin output against emerging requirements in environmental and consumer safety codes. The lessons we learn from lab-scale innovation get pressure-tested in mass-scale production, and the best outcomes become process standards for the future.

    Sourcing for specialty chemicals faces scrutiny from end-users and regulatory watchdogs alike. We continue to dedicate resources to certifications and voluntary audits not simply for compliance, but because we know that every verified drum protects the field reputation we have built batch by batch. As new applications emerge—antimicrobial clothing, slow-release farm treatments, next-gen water additive packs—we collaborate with customers to shape our chemistries and packaging to real application needs, understanding that batch traceability and concrete technical support turn a commodity product into a long-term industry solution.

    Conclusion: Decades of Direct Experience in Every Drum

    Our work with 5,5-Dimethylhydantoin combines bench-level chemical scrutiny and floor-level operator knowledge. From controlled batch technology to customer-driven upgrades, the result is a chemical intermediate that stands out for reliability, traceability, and genuine manufacturing support. Looking ahead, we will carry forward this approach as markets shift and applications evolve—continuing to support customers with practical, hands-on expertise and a product tailored for real-world process demands.