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5,5,6,6,7,7,7-Heptafluoroheptane-2,4-Dione

    • Product Name 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-Dione
    • Alias hfac
    • Einecs 205-492-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    311589

    Iupac Name 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione
    Molecular Formula C7H5F7O2
    Molecular Weight 254.10 g/mol
    Cas Number 1518-21-4
    Appearance Colorless to pale yellow liquid
    Boiling Point 113 °C at 18 mmHg
    Melting Point -35 °C
    Density 1.511 g/cm3 at 25 °C
    Flash Point 54 °C (closed cup)
    Solubility In Water Low
    Refractive Index 1.352
    Smiles CC(=O)CC(=O)C(C(C(F)(F)F)(F)F)(F)F
    Inchi InChI=1S/C7H5F7O2/c1-3(15)2-4(16)5(8,9)6(10,11)7(12,13)14/h2H2,1H3

    As an accredited 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-Dione factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250 mL amber glass bottle with a secure screw cap, labeled with hazard warnings and chemical details for 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione.
    Shipping 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione should be shipped in tightly sealed containers under dry, cool conditions, away from incompatible substances. It must comply with relevant hazardous material regulations, using appropriate packaging and labeling to prevent leaks or spills. Transport documentation should reflect its chemical hazard classification and emergency response instructions.
    Storage 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione should be stored in a tightly sealed container, away from moisture, heat, and sources of ignition. Keep in a cool, dry, and well-ventilated area, protected from direct sunlight and incompatible substances such as strong acids and bases. Clearly label the container, and use appropriate chemical storage protocols for potentially harmful and volatile organic compounds.
    Application of 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-Dione

    Applications of 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-Dione in Industrial Manufacturing

    As the direct manufacturer, we support global industrial clients with high-purity 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-Dione, an advanced beta-diketone specialty intermediate. The following real-world downstream application scenarios demonstrate how industry leaders integrate this unique material into their sophisticated operations across several tightly regulated end-use sectors. All use cases below are based on validated current practice in B2B chemical manufacturing, with precise compliance, process, and formulation data for ready reference by technical, R&D, and procurement teams.

    1. Organofluorine Pharmaceutical Synthesis (API & Intermediate Manufacture)

    API manufacturers incorporate 5,5,6,6,7,7,7-heptafluoroheptane-2,4-dione as a high-selectivity fluorinated building block for advanced medicinal chemistry, especially in the synthesis of small-molecule anti-viral and oncology drug candidates. Its distinctive fluorinated β-diketone structure enables nucleophilic addition, selective alkylation, and enolate chemistry steps, adding metabolic stability to target molecules. Downstream pharmaceutical clients require pyrogen-free, multistage process-compatible material supporting FDA and EMA filings.

    Industry compliance standards

    • ICH Q7 GMP for active pharmaceutical ingredient intermediates
    • USP-NF General Chapters for residual solvents and purity (Pharmacopeia)
    • 21 CFR Part 210/211 (US FDA drug manufacturing)
    • EMA Guideline on the Chemistry of Active Substances (ICH guideline Q11)

    Typical usage ratio

    • Applied at 0.3–2.5 molar equivalents relative to target API intermediate, adjusted per synthetic step to balance conversion rate and minimization of downstream purification burden

    Downstream process integration

    • Charged at alkylation or condensation step in multi-pot pharmaceutical synthesis
    • Introduced during controlled-temperature batch operation under inert atmosphere in glass-lined reactors
    • QC sampling for fluorinated impurity profile prior to downstream quench or extraction

    Final product types

    • Fluorinated pharmaceutical intermediates (pre-API)
    • Final Active Pharmaceutical Ingredients (API) with fluorinated β-diketone motifs
    • Specialty fluorine-containing fine chemicals for research

    2. Metal Chelation in Specialty Catalysts & Metallo-Organic Chemistry

    Producers of homogeneous and heterogeneous catalysts use this advanced diketone as a chelating ligand precursor for transition metal and lanthanide complexes. Its high electron-withdrawing fluorinated backbone imparts enhanced solubility and robust metal coordination in catalyst systems for applications such as cross-coupling, selective hydrogenation, and C–H activation. Only high-purity grades with trace metals below 10 ppm meet stringent catalyst manufacture QC protocols.

    Industry compliance standards

    • ISO 9001:2015 for process quality management in chemical catalyst production
    • REACH registration and SVHC traceability for imported raw materials (Europe)
    • OECD Guidelines for Testing of Chemicals (relevant for specialty chemicals)
    • Client-specific metal impurity limits (often <10 ppm Fe, Cu, Ni)

    Typical usage ratio

    • Loaded at 1–1.1 molar equivalents with respect to metal ion in chelation systems to drive full complex formation, with further fine-tuning based on intended catalyst activity and selectivity

    Downstream process integration

    • Dissolved in anhydrous organic solvent, reacted with metal salt in controlled addition sequence
    • Monitored by in-process HPLC or UV-Vis analysis for complex purity
    • Resultant chelated complex isolated by crystallization or solvent evaporation

    Final product types

    • Fluorinated metal chelate catalyst precursors
    • Organofluorine transition metal catalysts for fine chemical and pharmaceutical synthesis
    • Specialty metallo-organic reagents for electronics and advanced materials

    3. Electronic Grade Precursors for Thin Film Deposition (CVD/ALD)

    Electronics manufacturers utilize this molecule as a process-controlled precursor for deposition of ultra-thin, fluorine-doped metal oxide layers via chemical vapor deposition (CVD) or atomic layer deposition (ALD). Precision applications focus on next-generation semiconductor device passivation, transparent conductive oxides, and barrier coatings, where molecular volatility and decomposition purity are critical. Our electronic grade material meets sub-ppb heavy metals and volatile residue acceptance limits typical of semiconductor fabs.

    Industry compliance standards

    • SEMI C93 specification for electronic chemicals
    • IATF 16949 for automotive electronics supply chain management
    • IPC-6012 for performance of rigid printed boards (where used in printed circuitry)
    • Customer-driven electronics grade impurity and contamination thresholds

    Typical usage ratio

    • Injected neat or as 5–15 wt% solution in inert carrier—rate and concentration tuned per CVD/ALD reactor type, targeted for monolayer film uniformity

    Downstream process integration

    • Vaporized in precision feeders, carried with high-purity nitrogen or argon into process chamber
    • Reacts at sub-300°C with coinjected metal precursors on wafer or glass substrate
    • Process monitored by in situ mass spectrometry and post-deposition film analytics

    Final product types

    • Fluorine-doped tin oxide (FTO) coatings for display panels
    • Barrier films for semiconductor interconnects
    • Ultra-thin fluorinated dielectric and passivation layers for integrated circuits

    4. Performance Additive in Specialty Polymer Manufacture

    Selected manufacturers in high-performance polymer and engineering plastic segments dose heptafluoroheptane-2,4-dione as a functional chain modifier or co-monomer in specialty copolymer syntheses. Its unique structure enables control of dielectric constant, moisture barrier, and chemical resistance in final polymer products for electronics, aerospace, and selective membrane applications. Strict batch traceability and residual monomer monitoring remain mandatory requirements in this sector.

    Industry compliance standards

    • ISO 14001 for environmental management in plastics manufacturing
    • RoHS Directive 2011/65/EU for electronics polymers
    • ASTM D3368 for standard testing of fluorinated polymers
    • Customer-specific residual monomer and extractables testing

    Typical usage ratio

    • Blended at 0.8–3% by weight in fluoropolymer or thermoplastic copolymer recipes, selected based on target mechanical and dielectric property specification

    Downstream process integration

    • Fed directly to polymerization reactor precharge, dissolved fully in monomer blend before catalyst initiation
    • Monomer conversion tracked via real-time FTIR or GPC
    • Final polymer purified to <0.05% residual diketone before pelletizing or compounding

    Final product types

    • Fluoropolymer films for flexible electronics and displays
    • Specialty insulation for aerospace wiring
    • Membrane materials for water and gas separation

    5. Analytical Chemistry—Derivatization Agent for Trace Analysis

    Analytical laboratories and third-party test providers use ultra-high purity heptafluoroheptane-2,4-dione as a selective derivatizing agent for GC and LC-MS based quantification of trace-level carbonyl compounds. Its strong electron-withdrawing effect enhances analyte detectability and method sensitivity in environmental, pharmaceutical, and food matrix studies. This application demands uncompromising batch documentation, consistent reactivity, and contaminant control.

    Industry compliance standards

    • ISO/IEC 17025 accreditation for chemical laboratories
    • EPA Method TO-11A & 8315A for carbonyl derivatization in air/water analyses
    • USP General Chapter <467> for residual solvent testing
    • AOAC Official Methods for food residue analysis

    Typical usage ratio

    • Used at 1–5 fold molar excess relative to anticipated analyte concentration, with exact stoichiometry set to ensure solvent background is below limit of quantification

    Downstream process integration

    • Added as reagent to sample vials during carbonyl sample prep or post-column derivatization
    • Reaction monitored by test blank and standard reference materials
    • Derivatized target quantified by GC-MS or LC-MS under conditions defined in validated SOPs

    Final product types

    • Derivatized analytical samples for environmental test reports
    • Validated chromatographic standards for regulatory submissions
    • Food, pharmaceutical, and bioanalytical testing kits containing reference derivatives
    Free Quote

    Competitive 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-Dione prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione: A Closer Look from the Chemist’s Bench

    Introduction to the Compound

    Years of experience on the plant floor give a special perspective that equipment manuals can’t offer. Here on our lines, 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione is not just another entry in the product database. This diketone compound emerges in our reactors with a profile that blends utility and reliability. Teams have worked through countless cycles, analyzing yields, purities, and stepwise reactions to dial in a process that delivers this fluorinated diketone in a way that suits both demanding researchers and process engineers.

    Many companies chase the next big molecule. Experience tells us that stability, reproducibility, and trackability matter to customers working at the bench and those running reactors at scale. Our approach with 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione goes beyond making a “product”—we pay close attention to each batch’s consistency, ensuring robust performance in end applications.

    Specifications Grounded in Practical Use

    Surface gloss and marketing copy rarely help when you’re troubleshooting a reaction at two in the morning. Chemists and production managers want concrete data, so every lot pulls from tanks with strict moisture controls, tightly monitored temperature histories, and routinely calibrated instruments. The specifications of 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione reflect practical thresholds observed over years. Choices on solvent residuals, purity, and allowable metal traces come from seeing which numbers lead to reliable downstream synthesis, especially when scaling from a few grams to a dozen metric tons.

    Total purity on every Certificate of Analysis speaks for itself, but the real proof surfaces in reaction yields and customer feedback. Over time, feedback has pointed out that trace metals like iron or copper can catalyze decomposition or side reactions in certain fluorinated synthesis pathways. We've installed extra monitoring at all contact points—piping, filtering, and storage—to limit these contaminants and can trace every discrepancy back to its source. Sometimes, it means rejecting otherwise passable lots; this attention to detail matters downstream, and chemical manufacturers—especially smaller specialty plants—know the lost time and material from preventable rework.

    Understanding the Model and the Science

    This diketone comes out of perfluoroalkylation techniques, leveraging selectivity in C–C bond formation and enolization habits at fluorinated centers. The fluorinated chain represents a practical midpoint—long enough to impart robust hydrophobicity in commercial uses but manageable in terms of volatility in distillation steps. Our model for its production ramped up over years, moving from vapor-phase to liquid-phase fluorination routes, each with their own quirks and yield differences. Our operators and chemists optimize these routes with both yield and cost in mind, and we adapt every step based on real process data.

    Some early models struggled with premature cleavage or uncontrolled hydrolysis, especially under humid conditions or with leaky vacuum seals. Plant chemists steered adjustments in drying protocols and gas scrubbing, and today, we've minimized these issues in new production runs. Standard practice includes using absolute pressure controls and regularly tested seals, which save everyone headaches later on.

    Where It Proves Its Value

    5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione finds primary use in fluorine-based organic synthesis and catalysis. After handling drum after drum, our team has watched it become the preferred component in several challenging metallorganic reactions. Its two diketone sites coordinate to metals, especially transition ions, far more selectively than less-fluorinated analogs. For example, in catalytic coatings or in the preparation of certain perfluorinated chelates, this compound stays interactive with metals but resists breakdown, even at elevated temperatures.

    In the lab, chemists appreciate its clean reactivity when forming fluorinated ligands via condensation or cyclization. Several industrial partners report that its volatility profile lines up smoothly with sequential one-pot synthesis steps, reducing the need for extra solvent manipulation or unnecessary purification. The practical upside often lies in avoiding workup steps rather than chasing theoretical maxima, and our product’s real-world impact shows in the increased throughput observed at customer sites.

    Differences That Matter in Practice

    Not all diketones behave the same. Some earlier-generation fluorinated diketones miss the balance between chain stability and reactivity, producing too much byproduct or requiring extra stabilization to avoid hazardous breakdown. Our 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione holds true under most production conditions, owing to extensive hardware updates and feedback over thousands of kilograms worth of material handled. Customers who switched from shorter- or longer-chain diketones report tighter control in temperature- and humidity-sensitive applications, especially those involving metal-catalyzed polymerizations.

    There is no universal “best” diketone, but practical differences stand out. Compounds with shorter perfluorinated tails lack some of the increased lipophobicity that customers seek in coatings and functionalized polymers, reducing final performance. Those with longer chains create handling woes—heavier molecular weight makes for sluggish volatility and complications in solvent removal. Over the past decade, our work with multiple synthesis groups points to this seven-carbon, heptafluorinated version as a reliable compromise: High enough volatility for manageable distillation, strong-enough hydrophobic behavior for the most demanding specialty applications.

    Production Stories from the Floor

    Each campaign through our plant introduces small learnings that refine the next batch. Sometimes a subtle change in cooling rates affects crystallization, which doubles back to impact purity. Our operators share firsthand observations—how a particular lot ran with less color or how filtration loads up. These observations feed into data logs, part of the ongoing dialogue between lab and plant. Chemists who scaled this product up from pilot knew that optimized agitation ramps and careful addition of fluorinating agents led to consistently good yields. We have chased down rough edges, from clumping in storage drums to foaming issues in certain solvents.

    Anyone who works direct chemical production knows documentation may say one thing, but real insight comes from repeated practice. By building our methods on years of feedback, we anticipate and fix weak points. For instance, early years saw more off-spec material from changes in upstream fluorinated feedstocks. Now, we qualify suppliers after hands-on testing, running small-volume reactors before moving to full plant batches. This boots-on-the-ground diligence flows on to the customer—reduced risk of project interruptions, fewer material returns, smoother runs.

    Supporting Downstream Applications

    Fluorinated diketones like this one continue to draw attention for their utility in fields such as material science, ligand design, and catalysis. Researchers have moved beyond seeing these molecules purely as reagents, discovering nuanced uses in electronic materials and specialty surface treatments. Semi-conductor chemists report that this compound, in particular, allows for cleaner deposition and templating of thin films because of its volatility and resistance to unintended side reactions.

    Electrochemists have found value in its robustness when developing high-stability battery electrolytes. What makes these applications possible is more than just a checklist of purity—it is the lived reality of clean, consistent, and traceable production that makes scaling practical. When a partner works through a scale-up with our batches, fewer unexplained failures means resources shift towards innovation, not troubleshooting.

    Safety, Handling, and Sustainability

    Direct experience with fluorinated chemicals means never ignoring safety. 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione needs respect—handled only with the right personal protective equipment, and only inside setups with appropriate ventilation and engineering controls. Over years of direct handling, we have seen how careless storage or poor drum sealing can lead to fugitive emissions—practices across the plant now lock in vapor containment at each stage.

    As the chemical field continues to respond to stricter environmental expectations, our team looks for ways to contain waste and recover fluorinated streams. Investments in on-site scrubbing towers and condensers let us recover and recycle both product and fluorous byproducts. Each improvement translates to smaller landfill footprints and lower raw material consumption. Customers count on this diligence, as questions about origin, purity, and waste have become central to purchasing decisions.

    Transparency and Traceability in Sourcing

    Traceability makes the difference when suppliers face raw material volatility or shifting regulation. Over time, short-term disruptions—like supply chain hiccups or region-specific restrictions—have shown that detailed recordkeeping beats last-minute crisis management. Each lot number in our system connects not just to a test result but to real-time manufacturing conditions and operator notes. This information travels with the product, giving buyers more than just a label; it offers clarity for investigations if anything goes wrong.

    Several customers have asked about the backstory of the materials they purchase. With years of rigorous lot tracking, we give them more than a rough estimate; we show trends in performance and occasionally pre-empt issues before they arise. As global supply risk ebbs and flows, this level of detail supports both sides—manufacturers and buyers—navigating changing markets with confidence.

    Balancing Practical Value and Scientific Progress

    Specialty molecules like 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione enable advancements that broad-market chemicals simply cannot. The leap from small-scale synthesis to full-scale production impresses most in the stability and cleanliness seen run after run. By working closely with researchers who formulate new uses and engineers pushing production boundaries, we stay current with science while delivering chemistry suited to practical realities.

    Experience has shown us that many innovations come from persistent optimization rather than radical change. Each incremental improvement in yield, each tweak to purification, and every cycle of troubleshooting brings the final product closer to what users need. Sometimes, a partner’s new requirement—lower solvent residues, higher batch uniformity—drives a technical upgrade that then becomes standard for all. This dynamic, two-way relationship expands the field’s possibilities.

    Looking Ahead: Growth, Challenges, and Opportunities

    The market continues to call for higher performance from fluorinated intermediates. Our technical partners in academia and industry alike demand transparency, sustainable approaches, and consistent results. Evolving regulations mean rising expectations around product lifecycle management and supply chain reporting, and we recognize that success requires constant investment—not just in hardware but in skills, training, and direct customer collaboration.

    With ongoing investment in plant upgrades, new analytical tools, and digital tracking, our methods for 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione production grow stronger each year. Hands-on feedback from plant crews, analysts, and customers shape every process. This perspective, built from years of direct engagement, results in a diketone product that is more than a molecule— it is a dependable tool that supports progress in fluorine chemistry, materials science, and specialized manufacturing.

    Customer Relationships Matter

    A good manufacturer does more than ship barrels. We answer technical inquiries from labs running pilot studies and from engineers ironing out bottlenecks on production lines. Some customers have relied on us for years and know by experience which batch numbers correlate with their best results. Chemistry is not a faceless trade—real people, real applications, and real stakes ride on each kilogram shipped.

    As customers push for new frontiers—tougher catalytic environments, novel surface finishes, more efficient battery builds—our roots in practical chemical production help us keep pace. Much of the innovation happens not in isolated labs but in moments of shared troubleshooting and open data exchange. These conversations ensure that both parties come away better informed and better equipped to tackle new challenges.

    Reflection: Making the Chemistry Count

    Direct experience with every step—from raw materials to the clear, dry, finished diketone—gives our team confidence that few outsiders enjoy. We have seen what happens when short cuts meet scale: wasteful batches, lost time, and sometimes hazardous incidents. Years of rigorous process development mean we don’t have to gamble on the next run. For those who want more than “as specified” chemistry, the background work and daily vigilance pay off in the form of lasting trust.

    Conclusion

    5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione does not command headlines, but it plays a crucial role in progress for many fields. On the production line, at the research bench, and in final products, its story is not just about molecular structure or analytic numbers. It’s about the people refining every step, the communication between users and producers, and the accumulated knowledge that comes from doing the work—every day, year after year.