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4-Pyrazol-1-Yl-Benzaldehyde

    • Product Name 4-Pyrazol-1-Yl-Benzaldehyde
    • Alias 4-(1H-Pyrazol-1-yl)benzaldehyde
    • Einecs 422-280-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    873417

    Product Name 4-Pyrazol-1-Yl-Benzaldehyde
    Cas Number 3931-43-1
    Molecular Formula C10H8N2O
    Molecular Weight 172.19
    Appearance Off-white to light yellow solid
    Melting Point 93-97°C
    Boiling Point No data available
    Purity Typically ≥98%
    Solubility Soluble in DMSO, DMF; slightly soluble in water
    Smiles C1=CN(N=C1)C2=CC=C(C=C2)C=O
    Inchi InChI=1S/C10H8N2O/c13-8-9-2-4-10(5-3-9)12-7-1-6-11-12/h1-8H
    Storage Conditions Store at 2-8°C, protected from light and moisture

    As an accredited 4-Pyrazol-1-Yl-Benzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Packaged in a 25g amber glass bottle, tightly sealed, labeled with chemical name, formula, hazard symbols, and handling instructions.
    Shipping 4-Pyrazol-1-Yl-Benzaldehyde should be shipped in airtight, chemical-resistant containers, protected from moisture and direct sunlight. Packages must comply with local and international regulations for hazardous materials. Appropriate labeling, documentation (SDS), and robust packaging are essential to prevent leaks or contamination during transit. Ensure transport via reliable, approved carriers specializing in chemicals.
    Storage 4-Pyrazol-1-yl-benzaldehyde should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated chemical storage area, away from incompatible substances such as strong oxidizers. Clearly label the container and avoid prolonged exposure to air. Always follow institutional safety protocols when handling and storing this compound.
    Application of 4-Pyrazol-1-Yl-Benzaldehyde

    Applications of 4-Pyrazol-1-Yl-Benzaldehyde in Industrial Manufacturing

    As a manufacturer specializing in chemical raw materials for advanced industrial applications, we supply 4-Pyrazol-1-Yl-Benzaldehyde with consistent purity and traceability to accelerate process development in specialized downstream sectors. Below, we outline established commercial uses, including formulation parameters, regulatory guidance, integration points, and the end products adopted by industry leaders.

    1. Pharmaceutical Intermediates for Pyrazole-Based APIs

    Leading pharmaceutical companies integrate this raw material as a structural precursor in the synthesis of select pyrazole-containing active pharmaceutical ingredients, notably in non-steroidal anti-inflammatory drugs (NSAIDs) and targeted antitumor agents. The compound enters multistep synthetic schemes by providing a modifiable scaffold, facilitating further reactions like condensation or cyclization under GMP conditions.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia monographs for relevant APIs
    • US FDA 21 CFR Part 211 (cGMP)
    • Chinese Pharmacopoeia General Rules

    Typical usage ratio

    • 0.8–1.2 molar equivalents per key API moiety, adjusted by route yield and downstream impurity profile

    Downstream process integration

    • Serves as a core aldehyde input at the initial synthesis stage, followed by condensation reactions or cyclization in reactor vessels before purification and formulation into APIs

    Final product types

    • NSAID APIs such as Pyrazolone derivatives
    • Oncology small molecule drug intermediates
    • Specialty pharmaceutical compounds incorporating pyrazole rings

    2. Agrochemical Active Ingredient Synthesis

    Major agrochemical producers employ 4-Pyrazol-1-Yl-Benzaldehyde as a synthetic building block to create customized fungicides and herbicides with pyrazole-based pharmacophores. The compound undergoes controlled reactions with various halogenated aromatics and amines under strict HSE management in pilot plants, responding to seasonal product portfolios.

    Industry compliance standards

    • FAO/WHO Technical Guidelines for Pesticide Specification
    • REACH Registration and CLP Regulation (EC 1272/2008)
    • China National Standard GB 4839 for Agrochemicals
    • ISO 9001-certified quality management systems

    Typical usage ratio

    • 0.6–1.5% by weight in batch synthesis, tailored to the molecular structure of the target active ingredient

    Downstream process integration

    • Fed as a nucleophilic aldehyde during the intermediate combination stage under inert atmosphere before final formulation into technical concentrates

    Final product types

    • Selective pyrazole-derived herbicide formulations
    • Broad-spectrum fungicide technical products
    • Intermediate bulk ingredients for post-patent crop protection solutions

    3. Fluorescent Probe and Sensor Material Manufacturing

    Specialty companies in analytical sciences and sensor technology use this compound for constructing advanced fluorescent probes. The aromatic aldehyde acts as a conjugation anchor, enabling derivatization with diverse chromophores through Schiff-base formation, and is processed under tightly controlled lab-to-pilot scale protocols.

    Industry compliance standards

    • ISO 13485 for Analytical Device Components
    • RoHS 2011/65/EU Restricted Substances Directive
    • SMEGL (Standard Method for the Examination of Water and Wastewater) for lab-scale validation
    • Internal Quality Agreements with instrumentation suppliers

    Typical usage ratio

    • 0.1–0.5 mmol per probe batch, selected based on final dye payload and quenching properties

    Downstream process integration

    • Introduced at the conjugation step for covalent attachment to fluorescent moieties, typically via manual or automated reagent addition in microreactors

    Final product types

    • Ratiometric fluorescent sensor kits
    • Real-time environmental analyte probes
    • Biochemical assay reagents for research and diagnostics

    4. Fine Chemicals for Dye and Pigment Synthesis

    Manufacturers in the high-performance colorant sector incorporate 4-Pyrazol-1-Yl-Benzaldehyde into dye synthesis lines for creating novel heterocyclic pigments. The pyrazole ring system, introduced via stepwise arylation, provides improved thermal and photostability, which is valued in coatings and textile printing applications.

    Industry compliance standards

    • EU Regulation (EC) No 1907/2006 REACH Annex XVII for colorant chemicals
    • SQAS (Safety & Quality Assessment for Sustainability)
    • ZDHC (Zero Discharge of Hazardous Chemicals) Manufacturing Restricted Substances List
    • ECO PASSPORT by OEKO-TEX® (for select textile uses)

    Typical usage ratio

    • 3–8% in dye formulation solids, proportioned based on shade intensity requirement and pigment load

    Downstream process integration

    • Reacted as a principal aromatic intermediate during the colorant coupling phase preceding final purification, milling, and dispersion for application-specific concentrates

    Final product types

    • Heat-resistant specialty pigments for plastics and coatings
    • Reactive printing dyes for textiles
    • UV-stable dispersive colorants for industrial inks

    5. Electronic and Photonic Materials Synthesis

    Producers of niche electronic materials utilize this aldehyde as part of molecular design for organic semiconductors and charge-transport compounds. The introduction occurs under strictly inert, anhydrous conditions with high-purity reagents, facilitating customizable electronic properties through targeted pyrazole functionalization.

    Industry compliance standards

    • IEC 60747-1 for semiconductor device materials
    • ISO 14644 Cleanroom Class for electronic chemicals processing
    • RoHS and REACH substance conformity (EC 1907/2006 and 2011/65/EU)
    • TSCA Inventory (for U.S. electronic materials)

    Typical usage ratio

    • 0.2–2 mol% relative to total monomer load, optimized for the desired carrier mobility and polymer architecture

    Downstream process integration

    • Charged as an aldehyde building block during the monomer synthesis stage, followed by polymerization or deposition onto substrates in cleanroom reactors

    Final product types

    • Organic thin-film transistors
    • Photovoltaic charge-transport layers
    • OLED display material precursors

    6. Chemical R&D and Custom Synthesis Services

    Custom synthesis service providers and academic research laboratories source this compound as a targeted aldehyde for piecemeal assembly of proprietary molecules, particularly in the medicinal chemistry and advanced material science fields. It fits into design-driven processes demanding high-purity and reproducibility for complex target validation.

    Industry compliance standards

    • ISO/IEC 17025 Laboratory Accreditation
    • GLP (Good Laboratory Practice, OECD Principles)
    • Institutional Material Safety Data Sheet (MSDS) handling
    • Internal procurement and inventory control policies

    Typical usage ratio

    • Adjusted case-by-case: typically 0.05–0.3 grams per research batch, or scaled for pilot synthesis up to 1% w/w of total reaction mass

    Downstream process integration

    • Added as a defined reactant in stepwise laboratory synthesis or milligram-to-gram custom pilot runs, frequently followed by immediate analytic confirmation and scale-up evaluation

    Final product types

    • Reference standards for pharmaceutical R&D
    • Prototype materials for specialty chemical startups
    • Academic publication substrates in organic synthesis studies
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    Certification & Compliance
    More Introduction

    4-Pyrazol-1-Yl-Benzaldehyde: From Our Facilities to Industrial Innovation

    What Sets 4-Pyrazol-1-Yl-Benzaldehyde Apart

    We have spent decades perfecting the art and science behind 4-Pyrazol-1-Yl-Benzaldehyde, delivering a compound that offers reliability and chemical consistency for every batch. Our process begins with a careful selection of input materials. We run our synthesis under tightly managed parameters, so every molecule lines up correctly, reducing unwanted byproducts and keeping the purity above industry norms. 4-Pyrazol-1-Yl-Benzaldehyde is not just another building block—it’s a precision tool in chemical development, distinguished by a benzaldehyde core fused with a pyrazole motif at the 1-position. This arrangement grants a unique blend of reactivity and selectivity, qualities that cannot be matched by generic benzaldehydes or pyrazole derivatives.

    Model and Specifications Developed in Real Production

    The model we offer for industrial and research application reflects lessons learned from thousands of hours in control rooms and lab benches. We monitor batch consistency by regularly sampling during the reaction and running in-house HPLC and NMR confirmation. The specification profile typically shows purity levels exceeding 98 percent, limiting water and other aldehydes to trace amounts. Our confidence in every shipment comes not from meeting a generic certificate, but from a commitment to batch-level scrutiny and feedback.

    Those who have worked with lower grade or off-brand versions often report unpredictable reactions and trace contaminants that interfere downstream. By sticking to rigorous internal benchmarks, our customers experience fewer hurdles in scale-up and less troubleshooting when blending into larger syntheses.

    On the Utility and Value in Chemistry Workflows

    Experienced chemists know that the aldehyde functional group serves as a cornerstone in organic transformations. By anchoring the pyrazolyl fragment on the benzaldehyde, our product steps far beyond conventional aldehydes. Its structure invites nuanced chemistry: forming novel heterocycles, evolving new ligands, modifying pharmaceutical intermediates, and supporting several academic projects. Researchers needing access to 4-pyrazole frameworks consider this product essential. The benzaldehyde carbon lends itself to a variety of formylation and condensation reactions, while the pyrazole side supports additional substitution, metal coordination, and cycloaddition.

    We manufacture for projects where reliability is non-negotiable. This might be library synthesis in pharmaceutical discovery, where missteps in the first step cascade to failed scaffolds further down the line. In agricultural chemical research, users modify the product to challenge plant pests or boost growth regulators. Materials scientists modify the core to create ligands for metal-organic frameworks or catalysts. We have observed repeated orders from fields as diverse as dye intermediates, analytical chemistry, and academia. Performance in real reactions and feedback from industry R&D groups shape every improvement.

    The Difference Grows in Downstream Reactions

    Clearing the hurdles of batch-to-batch variation, our product shows predictable response in condensation or Mannich-type extension. Chemists frequently come back with stories about troublesome aldehydes that carry extra forms or arrive partially oxidized. The stringent controls during our production and packaging give them confidence—subtle bottlenecks clear up, yields stabilize, repeatability increases. In high-throughput applications, whether on a 5-liter or 500-liter scale, consistent composition avoids unplanned downtime or costly reruns.

    Formulation groups tell us that structurally similar aldehydes sometimes demonstrate interference with key downstream reactants or offer poor shelf stability. Our batches remain stable under normal storage for extended periods, thanks to routine impurity checks and packaging inside inert atmospheres. Chemists with other sources often relay concerns over traces of acids or moisture sabotaging delicate syntheses; our incoming quality checks and closed-system drying nips the issue before it reaches you.

    Listening to Real-World Challenges

    Much of the development behind this compound grew from practical requests: a customer needed a reliable pyrazole aldehyde for scale-up, another structured an SAR study on antifungal agents, someone else needed uniformity for chromatographic method development. With every new request, we tuned our process, reduced residual solvents, and refined protocols based on firsthand discussions. We adapted packaging sizes from research bottles to drums for process chemists, each run certified before shipment. These continuous upgrades don’t just come from regulatory push or industry trend—they arise because our customers face real challenges and the cost of a failed synthesis runs high.

    Beyond the Standard Benzaldehydes

    We set out to make a difference from day one by refusing shortcuts common to third-party resellers. While traders aggregate from various labs with little oversight, we keep every step in-house—handling, purification, storage. Other suppliers often struggle to report minor impurities; our labs have invested in analytics capable of detecting byproducts at levels as low as parts per million.

    Other aldehydes in the benzene family struggle to support such diverse chemistry, since they lack the nitrogen-rich ring that encourages new reactivity patterns. That pyrazolyl moiety fuses reliability and flexibility, opening avenues in ligand synthesis, protein-protein interaction studies, and elsewhere. Unlike plain benzaldehyde, this offering stays chemically versatile across a wider suite of conditions, resisting auto-oxidation and maintaining shelf life in various climates thanks to our post-processing and packing methods. We spent a long time tuning the workup, finding techniques that held the best color and purity, so you don’t have to worry about issues cascading down the process line.

    Relentless Focus on Purity and Process Feedback

    Nothing comes off our lines without accountability. Each ferment or synthesis batch starts with documented chain-of-custody, backed by real people tracing input materials and production steps. Batch records include observations by shift chemists, updates from control operators, and periodic spot checks. A profile of each lot’s properties lives in our archives for years, available to users on request. Customers testing a new reaction or running a pilot campaign speak directly to in-house chemists, so advice never gets lost in translation.

    Product integrity does not hinge on certificates alone. Real, verified testing beats unchecked assumptions. One missed impurity can sabotage a thousand experiments. Every drum or bottle carries not only an identifying batch code, but also a story—the feedback loops from last year’s campaigns, the lessons learned from a failed pilot, adaptations that kept safety margins wide open. Between these technical routines and the knowledge gained from every plant trial, the gap between ours and a generic becomes a chasm.

    Supporting Chemistry Beyond Paper Specifications

    Specifications aren’t placeholders for reality—they are living commitments, written in the successes and lessons of daily manufacturing. Our team doesn’t disappear once the shipment hits your dock. We answer questions from chemists troubleshooting new syntheses, relay best storage practices, and receive feedback on practical issues as they emerge. Stories arrive from university labs who hit yield slumps with imported compounds, only to recover productivity by switching to a stable supply. Contract manufacturing groups rely on batch-lot data, not marketing promises.

    By fostering this two-way dialogue and sharing insights into reaction troubleshooting, we help shorten project timelines and cut project waste. As new application fields emerge—hybrid materials, catalysts with unprecedented selectivity, agricultural agents in changing climate zones—the adaptability of 4-Pyrazol-1-Yl-Benzaldehyde grows. Technical teams, production managers, and R&D chemists all depend on confidence in every unit they receive. Our product’s history and proven track record offer that certainty.

    Less Waste, More Process Safety

    Every gram of byproduct matters. Working within production, we know inefficient reactions quickly turn into costly disposal problems or reduced yields. Our continuous process improvements include optimizing temperature ramps, solvent choices, and purification cycles. The current protocol streamlines workup steps, resulting in a cleaner product that supports greener downstream chemistry—less reprocessing, fewer side-products, and tighter process control.

    Our quality and safety teams grew from early lessons in risk management. Minimizing trace unwanted substances from early stages limits not just product recalls, but also operator exposure and hazard potential. These routines foster a safer site and produce a product that won’t bring surprises into your process lines or storage rooms.

    Direct Manufacturing: Transparency in Every Order

    As manufacturers, we value the transparency that begins inside our gates and carries through to clients. This approach sets us apart from third-party sellers, who may not fully grasp the challenges or innovations in the synthesis of 4-Pyrazol-1-Yl-Benzaldehyde. Whenever we send product, we have the testing records, scale-up notes, stable handling advice, and clear storage instructions ready. In those rare cases where a problem arises, support comes from someone who touched the product in real life—not from scripts or faceless support channels.

    Our doors also stay open to audits and visitor tours for key customers and technical partners. The ability to “show the work” behind the product becomes invaluable, building trust that extends from bench to plant.

    Feedback-Driven Evolution

    Every tweak and upgrade in our process arises from practice, not prediction. The routes and purification methods in place today evolved as customers pursued new transformations, ran multi-kilo campaigns, or required documentation to satisfy regulatory reviews. Handling feedback from real users, not just downstream distributors, means every lesson gets applied without delay.

    Sometimes we receive surprising feedback: a material that worked beautifully in discovery chemistry gets finicky at larger scale, or a new impurity appears with a change in solvent system. By maintaining a culture of responsiveness and two-way exchange, our teams turn minor problems into longer-term advantages—changing process parameters, revising drying steps, or tuning packaging to better handle seasonal fluctuations. This openness strengthens the final product and, by extension, the user’s results.

    Comparisons and the Road Ahead

    Placing our 4-Pyrazol-1-Yl-Benzaldehyde next to mass-distributed alternatives, obvious distinctions show up under any real-world scrutiny. The glassy, consistent appearance under visual inspection, tight melting range, and robust stability lend confidence that translates directly to chemical operations. With less lot-to-lot drift and more documentation per batch, unplanned downtime and spoilage become less likely.

    What also stands out is responsive technical support and access to the team that manufactured each lot. The human factor—hard-won experience, real troubleshooting stories, and process memory—comes bundled with every delivery. Chemists working on deadline or under new regulatory scrutiny value these advantages even more.

    Commitment Over the Long Haul

    Producing something as specific as 4-Pyrazol-1-Yl-Benzaldehyde requires more than textbook chemistry. Building and maintaining the line means managing supply chain interruptions, staying ahead of new compliance requirements, and investing each year in better analytical capability. This long-haul view brings stability to our customers in times when raw material costs spike or new regulatory frameworks appear.

    We know projects using our compounds aren’t just lines on a ledger—they are months or years of collective effort, sometimes determining the difference between a new launch and a missed market window. Our product, when matched to user projects, brings a measure of certainty to an often unpredictable field.

    A Conversation that Keeps Us Learning

    Our story with 4-Pyrazol-1-Yl-Benzaldehyde keeps evolving. Like every product that leaves our floor, its journey continues in cutting-edge labs, scale-up suites, and plant campaigns across the globe. Each bottle is more than the sum of its molecules; it represents the persistence, dialogue, and trust that comes from years of customer engagement and process control. We look forward to the next feedback call or success story, knowing every improvement sharpens not just our product, but also the tools of discovery our customers use.

    For those exploring new transformations, seeking answers to technical challenges, or demanding the kind of reliability that only comes from firsthand manufacturing, 4-Pyrazol-1-Yl-Benzaldehyde offers proven value. Our commitment stands—not just in certificates or product sheets, but in every conversation, every test, and every ton delivered.