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4-N-Propoxybenzaldehyde

    • Product Name 4-N-Propoxybenzaldehyde
    • Alias p-Propoxybenzaldehyde
    • Einecs 220-954-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    567974

    Name 4-N-Propoxybenzaldehyde
    Cas Number 34897-99-3
    Molecular Formula C10H12O2
    Molecular Weight 164.20
    Appearance Colorless to pale yellow liquid
    Boiling Point 259-261°C
    Density 1.046 g/cm3
    Refractive Index 1.531
    Purity Typically ≥98%
    Solubility Insoluble in water; soluble in organic solvents
    Storage Temperature Store at room temperature

    As an accredited 4-N-Propoxybenzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for 4-N-Propoxybenzaldehyde (25 grams) is a sealed amber glass bottle with a secure screw cap, labeled clearly.
    Shipping 4-N-Propoxybenzaldehyde is shipped in tightly sealed containers to prevent leakage and exposure. The packaging complies with chemical safety regulations and is clearly labeled with hazard warnings. During transport, it is protected from moisture, heat, and incompatible substances. Appropriate documentation accompanies each shipment to ensure safe handling and regulatory compliance.
    Storage 4-N-Propoxybenzaldehyde should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from sources of ignition, heat, and incompatible materials such as strong oxidizing agents. Protect from direct sunlight and moisture. Label the container clearly, and handle with appropriate personal protective equipment. Store according to local regulations for flammable and potentially harmful chemicals.
    Application of 4-N-Propoxybenzaldehyde

    Applications of 4-N-Propoxybenzaldehyde in Industrial Manufacturing

    As a direct manufacturer, we specialize in supplying 4-N-Propoxybenzaldehyde for clearly defined industrial applications. This compound plays a vital role in downstream chemical processes for pharmaceutical intermediates, fine fragrance synthesis, specialty dyes, agrochemical actives, and advanced material research. Below we detail its specific use cases, compliance requirements, dosage ranges, processing stages, and typical end product categories across several specialized sectors.

    1. Pharmaceutical Intermediate – Sartan Antihypertensive Synthesis

    In the pharmaceutical sector, 4-N-Propoxybenzaldehyde functions as a key intermediate in the synthesis of certain angiotensin II receptor blocker (sartan) APIs. It reacts in controlled condensation steps to build the core structures necessary for cardiovascular drug molecules, with stringent documentation for traceability and residual solvent monitoring as per regulatory guidance.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • EU GMP Part II / US FDA 21 CFR Part 210 and 211
    • Relevant DMF (Drug Master File) submission guidelines (e.g., US, EU, China)
    • Residue limits and purity testing under USP and EP monographs for intermediates

    Typical usage ratio

    • Integrated in multi-step synthesis at 1.0 to 1.2 molar equivalents per API batch; adjusted based on specific patented pathways and downstream yield targets.

    Downstream process integration

    • Enters as a pre-condensation reagent, utilized in initial or second synthetic steps, followed by reductive amination or cyclization; processed under inert atmospheres with full batch QC for both identity and purity of intermediates.

    Final product types

    • Losartan potassium API
    • Valsartan API
    • Other related sartan antihypertensive bulk drug substances

    2. Fragrance Compound Manufacture – Aldehydic Perfume Ingredient

    Perfume and fine fragrance formulators include this aldehyde derivative to impart clean, slightly woody and floral notes, serving both as a characterising ingredient and as a reactive intermediate for proprietary aroma chemicals. Strict attention to purity profiles, low odor impurities, and trace safety component benchmarks is standard protocol for major global fragrance houses.

    Industry compliance standards

    • IFRA (International Fragrance Association) Purity & Safe Use Guidelines
    • EU REACH Registration for Fragrance Chemicals
    • ISO 9235 (Aromatic Raw Materials Definitions and Criteria)
    • Allergen profiles per EU Cosmetics Regulation (EC) No 1223/2009

    Typical usage ratio

    • Used in blends at 0.02–0.3% w/w of total perfume concentrate; varies based on finished perfume composition and regulatory threshold for aldehydic notes.

    Downstream process integration

    • Added during the exothermic mixing phase for high-value accords, typically after core base oils are established; monitored by gas chromatography for batch-to-batch reproducibility and low ppm impurity tracking.

    Final product types

    • Luxury eau de parfum bases
    • Premium personal care fragrances
    • Functional perfumery for soaps and detergents

    3. Dye & Pigment Intermediate – Aromatic Aldehyde Condensation

    Dye manufacturers use 4-N-Propoxybenzaldehyde as an electrophilic aromatic building block in Schiff base dye synthesis, where its propoxy group modulates chromophore properties and solubility. Each batch undergoes verification under color strength and purity assays, and production is aligned with international chemical management protocols for colorants.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (Textile Dye Safety)
    • ETAD Code of Practice for Safe Handling of Colorants
    • ECHA REACH Regulation for Dye Substances
    • ISO 9001:2015 Certified Production Management

    Typical usage ratio

    • Introduced at 0.8–1.5 molar equivalents in condensation reactions; the ratio varies based on the depth of shade and target solubility for the dye series.

    Downstream process integration

    • Charged into batch reactors during the nucleophilic addition phase for azo or anthraquinone dye formation, followed by pH adjustment and filtration; finished pigment undergoes HPLC and spectrophotometric quality checks.

    Final product types

    • Organic pigments for specialty inks
    • Textile dye intermediates
    • Colorants for plastics and coatings industries

    4. Agrochemical Intermediate – Herbicide & Fungicide Synthesis

    Chemical crop protection formulators use this material to construct selective herbicide and fungicide actives. It supports the molecular architecture in synthetic pathways for modern agrochemical agents, rigorously managed with full traceability, eco-toxicology review, and impurity mapping as per production site compliance.

    Industry compliance standards

    • FAO/WHO Specifications for Pesticide Active Ingredients
    • OECD Guidelines for Testing of Chemicals
    • EU Regulation (EC) No 1107/2009 (Plant Protection Product Approval)
    • ISO 17025 Laboratory Accreditation for Quality Control

    Typical usage ratio

    • Integrated at 0.9–1.2 molar equivalents per synthesis batch, adjusted according to desired yield and purity of the downstream active ingredient.

    Downstream process integration

    • Reacted in controlled alkylation or acylation steps, often forming part of a side-chain assembly prior to cyclization or esterification; final crude is worked up by multi-stage crystallization and analytical confirmation.

    Final product types

    • Triazole-based systemic fungicide actives
    • Pre-emergence herbicide agents
    • Custom intermediates for proprietary agrochemical pipelines

    5. Specialty Chemicals – Custom Ligand Synthesis for Materials R&D

    Emerging applications in advanced materials research rely on unique aromatic aldehydes such as this substrate. Research labs and pilot-scale producers use it for synthesizing custom ligands or organic building blocks utilized in OLED, catalysis, or coordination polymer studies, with documentation aligned with project-specific QC and analytical requirements.

    Industry compliance standards

    • GLP (Good Laboratory Practice) for Synthesis R&D
    • ISO/IEC 17025 for Analytical Method Validation
    • Institutional Chemical Hygiene and Material Safety Protocols
    • Contract-specific Specified Analytical Parameters (e.g., NMR/GC-MS confirmation)

    Typical usage ratio

    • Dosed precisely based on stoichiometric requirements; typical integration at 1.00 ±0.05 molar equivalent in ligand or prepolymer formation with strict adherence to pilot batch specifications.

    Downstream process integration

    • Employed during condensation or Schiff base formation, under strictly controlled environments; downstream workup includes repetitive purification and structural clarification.

    Final product types

    • Functionalized organic ligands for OLED development
    • Coordination polymers for catalyst screening
    • Novel sensor substrates for analytical instruments
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    Competitive 4-N-Propoxybenzaldehyde prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 4-N-Propoxybenzaldehyde: Experience, Purity, and Practical Value from a Chemical Manufacturer

    Direct from Our Reactors, Not Through Intermediaries

    Over the years, we have seen niche chemicals quietly shape entire industries behind the scenes. Not every molecule grabs headlines. Some simply keep processes running and formulations reliable. In our line of work, 4-N-Propoxybenzaldehyde often plays that behind-the-scenes role. Because we run the reactors and quality control lines ourselves, we know the material’s strengths, its quirks during handling, and the difference that real process consistency delivers for customers.

    Model, Purity, and Specifications: Honesty from the Source

    4-N-Propoxybenzaldehyde, also known as p-Propoxybenzaldehyde, appears as a pale yellow liquid at room temperature. Typical batches come from our facilities at purities of at least 99%. Our focus is strict control from raw material selection through to careful distillation, with each drum or small package holding exactly the batch we're proud to represent as our own. Impurity profiles stay consistent, clocking in near undetectable limits by GC analysis. Our customers routinely run their own checks and establish trust through numbers, but we trust every lot because we watch every step.

    We work with clients in pharma intermediates, fragrance oils, and specialty coatings. Each sector carries its own demands. Over time, we've learned how a stray impurity or a slight off-odor can wreck a batch downstream. Some manufacturers cut corners by relabeling, reselling, or blending subpar lots. As a manufacturer with skin in the game, we supply from our direct lines only. Nothing enters our inventory without complete traceability and up-to-date documentation. Manufacturing on our own lines, we control runtimes, temperature profiles, solvent recovery, and packaging integrity. That real-time oversight gets built into every product certificate that ships out.

    Understanding Where 4-N-Propoxybenzaldehyde Succeeds

    Many buyers hear about 4-N-Propoxybenzaldehyde as a customizable building block in aromatic aldehydes. Its propoxy group opens up chemistry where more standard benzaldehydes fall short. We see formulators who need finely tuned hydrophobicity or who want to push a delicate aromatic note in fragrance design. Medicinal chemistry uses emerge when a certain steric bulk or electronic effect is needed at the para position.

    End users in the coating industry appreciate the aldehyde’s ability to crosslink or modify polymers and resins, giving products with just the right balance of flexibility and hardness. Those working in flavor chemistry have cited its unique aromatic profile, though applications in flavors should stay aware of regulatory boundaries. Our own experience has taught us that 4-N-Propoxybenzaldehyde remains reliable for further derivatization—amide, oxime, and hydrazone formation all proceed cleanly with right process control. The compound's consistent reactivity simplifies downstream processing, keeping labor costs and error rates low.

    Some see 4-N-Propoxybenzaldehyde as a specialty luxury, reserved for boutique syntheses only. We know, from the dozens of metric tons shipped each year, the molecule is no lab curiosity. For process chemists who need a repeatable, tunable aromatic aldehyde, it often outpaces simpler options—especially when isolation, purity, and ease of handling matter. Our drums show up clear and with a mild scent, not with the lingering off-notes sometimes found in earlier generation materials.

    Comparing 4-N-Propoxybenzaldehyde to Other Aromatic Aldehydes

    Seasoned chemists will remember the familiar “vanillin problem”—using vanilla-emulating benzaldehydes where purity lags or performance drifts, especially at scale. With our processes, 4-N-Propoxybenzaldehyde avoids those common headaches. Its propoxy side chain modifies both physical and chemical behavior. Compared to plain benzaldehyde, our propoxy derivative resists volatility, lending more control in reactions that demand slow, precise additions. Handling is noticeably easier. Less loss to evaporation, tighter headspace requirements, and less odor in storage areas.

    Even when evaluated alongside other para-substituted benzaldehydes—like p-methoxy or p-ethoxy variants—our propoxy compound fills a distinct niche. With slightly higher molecular weight and more hydrophobic character, it survives harsher conditions and resists water-based separation losses during workup. End-use applications in UV-cured coatings, for example, benefit from these subtle differences. Analytical labs have confirmed for us that our propoxybenzaldehyde leaves less residue, distills more cleanly, and gives better yields in ether-soluble systems.

    Some see price as the prime difference. As direct manufacturers, our price stability stands on lower overheads and direct supply, not cutthroat shortcuts. That cost advantage trickles into each quote but never at the expense of analytical quality. If purity drifts outside spec, the batch gets rerun, not resold. We have stood by this policy longer than most brokers have kept their own stockrooms.

    Our Real-World Experience: Handling and Delivering Consistency

    Much gets written about chemical purity, but fewer talk about the day-to-day practicalities of moving, storing, and dosing real materials. In our warehouses, 4-N-Propoxybenzaldehyde stores cleanly in high-density polyethylene drums. Over decades, we have moved away from metal due to the aldehyde’s sensitivity and tendency to pick up metal-catalyzed discolorations. Little details add up: UV-resistant drums prevent color shifts, and turned inventory reduces degradation. It remains stable under regular warehouse conditions—out of direct sunlight, at ambient temperature—without risk of spike decomposition or leaching. Slight cloudiness sometimes alarms new buyers, but we've documented this as a temperature effect only, clearing again at normal process temperatures.

    As a manufacturer, we carry out technical consultation on request. Clients sometimes request guidance on solubility or compatibility with solvents. Ethanol, ether, and most aromatic solvents dissolve our material readily. Water exclusion remains important; even trace hydrolysis can alter both odor and effectiveness for certain fine chemical applications. For instrument calibration or analytical work, our lots feature batch-specific certificates, always tied to our internal QC results. We do not source from third parties and relabel as our own—a real assurance in markets prone to shadow blending.

    Shipping demands reliability. Our logistics teams have mastered multi-barrier sealing for international transport, with tamper-evidence, full paperwork, and MSDS direct from our in-house technical writers. Over the past five years, our shipping reject rate for visible defects has stayed below one in five thousand units, tracked openly with clients. We respond to inquiries personally. Often, buyers appreciate an open line to the chemists and operations people who make the actual batches.

    How Our Clients Use Our 4-N-Propoxybenzaldehyde

    A story from one coatings manufacturer illustrates typical experience. They needed a consistent aromatic modifier that wouldn't introduce tint drift or cloudiness. Trials with benzaldehyde and p-methoxybenzaldehyde—a competitor suggested their “equivalent” compound—produced uneven results. On switching to our propoxy-grade, they found a stable end product, no batch-to-batch color drift, and longer shelf life. No need for expensive reformulations or new stabilizers.

    Perfume houses often reach for p-alkoxybenzaldehydes as building blocks in complex accords. Feedback to us focuses on batch-to-batch aromatic clarity—one small difference between our material and the generic stock exchanged by traders. Fragrance chemists experience frustration with musty undertones or conflicting scent notes caused by impure material. We track every odor complaint to the supply chain, time of year, and batch—correcting process points at the reactor if needed. Our transparency earns loyalty, not price games.

    Pharmaceutical intermediates count on high-purity aldehydes for clinical lot synthesis. Here, the slight differences in impurity profile mean more work for the analytical lab—or sometimes a failed regulatory submission. Synthesis teams relay to us whether downstream reactions yield higher or lower than expected, and our chemists adjust process accordingly. One major client cut cycle time by three days per batch after switching to our material, simply by dropping the need for an additional purification step.

    Addressing Potential Issues and Solutions from a Manufacturer’s View

    Even the best process meets obstacles. Hydrolytic breakdown looms in humid or poorly stored conditions, creating byproducts such as acids and alcohols. Many clients have experienced headaches from aldehyde self-condensation in hot climates or slow shipments. We mitigate this by reducing time from reactor to drum, choosing antioxidants where permitted, and providing ongoing storage guidance. Regular rotation ensures material never lingers past prime usability—a simple practice too often ignored by non-manufacturers.

    Health and safety considerations demand respect. We’ve logged hours on safe handling practices, spill mitigation, and odor management. Strong, concentrated aromatic aldehydes can cause skin and eye irritation. We recommend—based on our working conditions—industrial nitrile gloves, fume extraction, and careful packaging break-down. Unlike some off-the-shelf or poorly repackaged materials, ours does not exhibit sudden surges in vapor pressure or unpleasant surprises on opening. We supply accurate SDS with every shipment and make technical staff available for unusual questions or custom storage needs.

    Shelf-life can stretch reliably past a year with correct handling, and every batch receives a production date and certificate tied to a precise analytical fingerprint from our own labs. If even tiny anomalies appear in repeat analyses, we share this with downstream partners and investigate source materials and equipment logs. This transparency means customers set up fewer repeat inquiries, and we get clearer feedback to improve process or packaging steps.

    Why Direct Manufacturing Delivers More Than Just a Molecule

    The conversation with bulk users and specialty formulators always circles back to trust: who made the lot, how was it run, and what might have changed since last order. Our clients tell us their time matters most—no one wants delays tracing a contaminant or explaining a color drift to end customers. We prevent those headaches by refusing third-party material, issuing true batch certificates, and keeping a technical team on-call for every load.

    Many in the market forget where risk creeps in. Aggressive traders “find” cheaper material by skipping testing or masking quality drift with excipients. In contrast, we own the process, from sourcing base aromatic compounds through to final filling. This gives us leverage to push for quality improvements each year. We’ve reduced energy usage per batch by 18% since 2020, invested in vapor recovery, and replaced legacy filtration to further cut down on off-odors. These advantages trickle to the product—not just in analytically cleaner results, but in lower overall cost and sustainability for large-scale buyers.

    Since we are the ones blending solvents, monitoring temperatures, and walking the packing floor, our accountability goes beyond a standard quality certificate. Most of our staff has clocked years on these lines, and our top process engineers grew up inside the facility—knowing the difference between theory and daily execution.

    Technical Improvements and Future Directions

    Demands change. Five years ago, no one anticipated the shift in regulatory compliance or the current appetite for green chemistry certification. We log every modification in our materials, tracking not just purity but also carbon footprint metrics and solvent recycling rates. Where customers request new blend ratios or integration with automation, our R&D works on flexible small-batch trials. On client request, we adapt drying and packing schedules for seasonal shifts or new formulation trends. The push to reduce solvent emissions and tighten batch records came first from in-house staff, not outside auditors.

    For technical teams, process repeatability and waste reduction mean more than certificates. Our staff meet regularly with key users to gather feedback, logging not just problems but small wins: faster blending, easier dosing, or lower odor complaints on the production floor. As a manufacturer, we welcome customer requests for pilot lots, custom volumes, and package sizes right up to jumbo totes or mini-samples for research groups. It’s common for process engineers to contact us directly about possible wrinkles in exotic syntheses—scaling up a novel step or retrofitting a process line with new aldehyde feeding. Our specialists love engaging in these problem-solving efforts, engineering incremental improvements that rarely make it onto broker datasheets.

    Over time, we have fielded questions about possible bio-based routes or greener starting materials. The shift to more sustainable feedstocks is a work in progress. Direct dialouge with clients alerts us to upcoming changes, keeping our facility flexible enough to adjust as regulations shift or as new catalyst systems go commercial. We see this as the foundation not just for one product, but for the full aromatic aldehyde range.

    Trust Earned by Making, Not Just Marketing

    Any sales pitch for 4-N-Propoxybenzaldehyde must reckon with reality: chemistry works in messy, unpredictable ways, especially without tight manufacturing control. We manufacture every drop that leaves our site, and we back every certificate with real in-house data. Trading houses or resellers cannot make those claims with the same level of reassurance. Real value grows from partnership, not just product sales.

    Over decades, we have learned that honesty, process reliability, and technical openness carry further than specs sheets or template copy can convey. Our batches show the fingerprints of makers, not just marketers. Every improvement in storage, handling, or purification builds confidence for our partners—from the smallest startup formulation shop to multinationals running full-scale synthesis reactors. The direct experience we gather every day turns into practical advice and performance feedback, which guides both our production team and our clients' R&D. Our approach means fewer supply interruptions, more reliable pricing, and cleaner, safer working conditions for everyone involved.

    To sum up, 4-N-Propoxybenzaldehyde in our hands isn’t merely another aromatic aldehyde on a generic price list. It is a specialty material shaped by years of process expertise, clear technical communication, and a refusal to compromise on origin, tracking, or handling. We have stood by our clients through troubleshooting, scaling up, and regulatory challenges alike. Owning the process from start to finish lets us deliver performance—not just promise it.