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4-Methylaminophenol Sulfate

    • Product Name 4-Methylaminophenol Sulfate
    • Alias Metol
    • Einecs 202-084-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    311053

    Chemical Name 4-Methylaminophenol Sulfate
    Synonyms Metol sulfate, N-Methyl-p-aminophenol sulfate
    Molecular Formula C7H11NO3S
    Molecular Weight 205.24 g/mol
    Appearance White to off-white crystalline powder
    Solubility Soluble in water
    Melting Point 170-175°C (decomposes)
    Cas Number 55-55-0
    Ec Number 200-237-1
    Storage Conditions Store in a cool, dry place, away from light and oxidizing agents

    As an accredited 4-Methylaminophenol Sulfate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for 4-Methylaminophenol Sulfate (100g) is a sealed, amber glass bottle with detailed safety and identification labels.
    Shipping 4-Methylaminophenol Sulfate is shipped in tightly sealed containers to prevent moisture exposure and contamination. The chemical is classified as a hazardous material and handled according to applicable regulations, including proper labeling. It is transported in a secure, upright position with supporting documentation, ensuring safety and compliance during transit.
    Storage 4-Methylaminophenol Sulfate should be stored in a cool, dry, well-ventilated area, away from incompatible substances such as strong oxidizers and acids. Keep the container tightly closed and protected from light and moisture. Store at room temperature, ideally between 15–25°C (59–77°F). Use appropriate chemical storage containers, and label them clearly to ensure safe handling and easy identification.
    Application of 4-Methylaminophenol Sulfate

    Applications of 4-Methylaminophenol Sulfate in Industrial Manufacturing

    With decades of expertise in the synthesis and quality control of 4-Methylaminophenol Sulfate, our production supports leading businesses across key industrial sectors. Below we detail how downstream industries integrate this compound into their proprietary processes, covering compliance requirements, processing stages, dosing guidance, and typical end products.

    1. Photographic Developer Chemicals

    Photo imaging manufacturers employ 4-Methylaminophenol Sulfate as a core reducer in black and white photographic developer formulations. Its electron-donating properties ensure consistent negative and print development, even under varying exposure and agitation conditions. Fine-tuning dosage allows processors to manage grain size and image sharpness, addressing different film speeds and emulsions. Quality and purity tightly correlate with processing consistency and shelf life, which is why professional photo chemistry plants demand high analytical standards.

    Industry compliance standards

    • ISO 18919:2018 (Image stability—Photographic films and papers)
    • ANSI/NAPM IT2.19—Stability of photographic chemicals
    • Factory GMP for photographic compounds

    Typical usage ratio

    • 0.6–1.2 g/L in working developer solutions; variation depends on developer type (paper or film), emulsion sensitivity, and process speed requirements

    Downstream process integration

    • Dissolved directly in aqueous concentrates, then diluted and combined with alkali, restrainers, and other reducers during batch formulation; added prior to filtration and sterile filling

    Final product types

    • Photographic paper developers (liquid/powder form)
    • Black and white film developers
    • Monobath rapid-process developer kits

    2. Hair Dye Intermediates Manufacturing

    Professional hair colorant producers utilize 4-Methylaminophenol Sulfate as a key precursor for high-performance oxidative hair dye shades. The compound acts as a coupler in dye formulations that generate durable, intense black and brown hues after activation with hydrogen peroxide. Accurate batching and purity control prevent color drift and ensure regulatory safety for end users. Colorant houses rely on granular compliance tracking during blending, oxidation, and post-processing stages, maintaining batch traceability through strict documentation and QC protocols.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 (Cosmetics Regulation)
    • U.S. FDA 21 CFR 73.2396 (Hair dye ingredients—Color Additives)
    • Japan MHLW Positive List of Cosmetic Ingredients
    • Good Manufacturing Practice ISO 22716

    Typical usage ratio

    • 0.05–0.35% by weight in the finished dye cream, adjusted for target shade intensity, formulation matrix, and regional regulations

    Downstream process integration

    • Added to dye coupler blends during pre-emulsion phase, co-dispersed with other intermediates, then homogenized before tube or bottle filling; tested in model oxidative system for shade calibration

    Final product types

    • Cream hair dyes (professional and consumer formulations)
    • Permanent hair color gels
    • Oxidative hair dye powders for salon use

    3. Analytical Reagents for Laboratory Diagnostics

    Diagnostic kit manufacturers specify 4-Methylaminophenol Sulfate for use in enzymatic and colorimetric test systems, particularly where precision in redox potential is critical. As a chromogenic substrate and redox indicator, it supports accurate quantification in clinical assays and environmental analyses. Traceability and batch reproducibility are paramount, with all materials sourced under validated supply chain protocols and extensive in-house testing prior to reagent kit assembly.

    Industry compliance standards

    • ISO 13485:2016 (Medical device quality management systems)
    • ISO 9001:2015 (Quality management)
    • USP Analytical Reagent Grade (where applicable)
    • REACH Annex XIV (Substance Registration for EU supply)

    Typical usage ratio

    • 2–8 mg in 5–10 mL final test volume (0.02–0.16%), depending on assay sensitivity, kit type, and target reaction endpoint

    Downstream process integration

    • Weighing and dissolving into buffered assay diluents during reagent compounding stages; filtered and filled into stabilized kit vials under nitrogen or inert conditions before final QC

    Final product types

    • Enzyme-linked immunosorbent assay (ELISA) substrate kits
    • Automated clinical chemistry reagents
    • Water pollution colorimetric test kits

    4. Specialty Fine Chemicals Synthesis

    Custom molecule manufacturers and contract synthesis facilities use this compound as a highly selective reducing agent and chemical intermediate in multi-stage syntheses. Its electron transfer characteristics are valued in targeted amine functionalization, where precise stoichiometry and batch monitoring drive product consistency. Handling and waste protocols address its amine sulfate content, ensuring environmental and safety compliance through validated process documentation.

    Industry compliance standards

    • ISO 9001:2015 (Quality management for fine chemicals)
    • Responsible Care® initiative (chemical safety stewardship)
    • National Fire Protection Association (NFPA) chemical hazard regulations

    Typical usage ratio

    • Varies from 1–10 mol% relative to limiting substrate, adjusted based on required degree of reduction or substitution in target molecule pathway

    Downstream process integration

    • Charged during reduction, amination, or condensation reactions in jacketed reactors; addition monitored via in-line analytics and pH/ORP meters to control reaction kinetics and selectivity. Quenching and purification steps follow before product isolation.

    Final product types

    • Custom dye intermediates
    • Pharmaceutical building blocks (non-API)
    • Specialized polymers and oligomers
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    Certification & Compliance
    More Introduction

    4-Methylaminophenol Sulfate: Working Experience from the Production Line

    Understanding the Product from a Manufacturer’s Perspective

    Every batch of 4-Methylaminophenol Sulfate we finish signals hard work, scientific rigor, and constant improvements. Looking at this compound under factory lights, we see more than a technical name—we see a chemical trusted by professionals who depend on its consistency every week. From its crystalline white powder to the characteristic faint amine-like odor, we notice these details—because our process from raw materials to refined product shapes everything downstream.

    On our side, 4-Methylaminophenol Sulfate typically takes the model name ‘MAP Sulfate’ as shorthand. International buyers sometimes know it by its CAS number, or simply as an essential development agent for silver halide photography. We run quality checks on appearance, purity by HPLC, inorganic salts, and moisture—knowing which grades matter most for each client. Most labs ask for a minimum purity of 99%. For specialty film developers, some request tests below the decimal point.

    Honed by Years of Chemical Synthesis

    We learned that getting high purity isn’t a matter of chance. It takes careful control—the right cooling regimes, enough agitation, minimum soluble iron contamination, and a vigilant watch over color development in final crystallization. Our team has fine-tuned these steps because a small slip can change downstream developer performance or cause instability. Early in our manufacturing history, we discovered that even trace copper ions spoiled the color response in photographic emulsions. We began using improved glass-lined reactors and restricted metallic pipework to reduce that risk. A chemical manufacturer grows by listening to customers’ issues and applying tight controls.

    Our finished MAP Sulfate stays stable under proper storage—dry, sealed, and away from acids. Moisture or acid vapors can break it down, so we switched to double-laminated packaging and dedicated storage areas. These steps came out of customer feedback from photo-processing plants that reported degradation under humid coastal climates.

    Experience with Usage—Why Laboratories and Industry Trust MAP Sulfate

    The most familiar use remains in photographic film and paper developers, where MAP Sulfate plays a primary reducing role, converting latent silver halide images to visible metallic silver. It’s an old technology, but demand from black-and-white film users, X-ray consumables, lithographers, and specialty film makers endures. Several large photo labs have told us that switching to lower-purity or off-brand product led to fogged images, poor contrast, or unstable shelf life. Because we supply directly from our synthesis lines, we control trace mineral and organic impurities—so these problems don’t reach our partners.

    Beyond photography, academic and research chemists use MAP Sulfate as a building block in organic syntheses, particularly in the preparation of complex polyphenolics or as an antioxidant. Some research teams order the same lot numbers for over a decade, precisely because switching suppliers disrupted their multi-step reactions. Field technicians in metallographic labs sometimes substitute it as a reducing agent for analytical samples. For these applications, consistency and absence of interfering side products matter as much as price, and we’ve learned which synthetic variants serve these needs best.

    What Sets Our MAP Sulfate Apart?

    Every batch carries our process fingerprint. We don’t lightly modify formulations for quick profit. This chemical can appear “standard,” yet details such as particle size, flow characteristics, and trace metal content distinguish high-functioning product from generic. We adopted sieve fraction monitoring after long-term customers in the photo industry pointed out that lumped or caked product slowed down their automated feed hoppers. Changing drying parameters solved the problem, but we understood it only because their feedback came straight to our technical team.

    With years on the synthesis floor, we’ve learned differences others overlook: fresh product that dissolves clear on first addition, no floating insoluble residues, zero caking during overseas transport, and no off-odors that could indicate decomposition. Each of these can spell the difference between a bottle that sits unused and chemicals that run through kilometers of photographic paper every day. We receive no value from withheld improvement—if a step makes MAP Sulfate more versatile or robust, we add it to our process.

    Comparison with Competitive Compounds

    Labs and industrial users often ask about swapping MAP Sulfate with other developing agents, and only manufacturers understand the real trade-offs. Compared to p-Aminophenol, MAP Sulfate develops images with faster kinetics, truer low fog, and greater shelf stability in solution due to its sulfate counterion. As producers, we see the batch-to-batch subtlety: sulfonated or carbonate-based derivatives can bring similar redox power but introduce solubility problems or higher levels of by-products that alter final results. MAP Sulfate breaks down differently, forming fewer colored impurities under alkaline or neutral conditions, which is why film professionals rely on its clean operation.

    Other suppliers sometimes market cheaper, loosely specified developing agents as “equivalent” in use. We have bench-tested these in our own quality labs. As a manufacturer, we’ve documented their higher trace metal content, erratic flow, and easy air oxidation on aging. These facts drive home why many photo labs, medical X-ray film processors, and technical paper manufacturers remain loyal to true MAP Sulfate. Over decades, feedback from these sectors pushes our continual process upgrades, not just cheapest output.

    Day-to-Day Manufacturing Challenges and Solutions

    Real manufacturing comes with issues. Sometimes, summer humidity spikes raise clumping or caking risks. Instead of blaming users, we increased the silica gel packets in packaging and chose new lot-specific moisture screening. If a customer reports off-color crystals, our team dives into batch logs tracing raw material supply, water purity, and even headspace oxygen during final drying. We hear often from small labs unfamiliar with best storage practice, so we include brief, clear guidance—no jargon or empty warnings. Avoiding confusion builds trust, and trust leads to repeat orders.

    The global supply chain for specialty chemicals proved fragile during supply crunches. To keep orders moving, we set up backup reactors and began requiring in-country environmental documentation for all soda ash and aniline sources. If a key pharmaceutical client flags even a minor specification deviation, we run out-of-band tests and share the full batch record transparently. Our production rhythm ties directly to user trust—one failed batch costs years of reputation.

    Safety Focus and Environmental Responsibility

    Handling 4-Methylaminophenol Sulfate takes knowledge. It can irritate skin and eyes, especially in concentrated solutions, and prolonged exposure presents occupational hazards. On our factory floor, training includes direct, practical scenarios, not just check-the-box paperwork. Our team wears nitrile gloves, goggles, and uses closed transfer pumps. Years of experience showed that low-level dust carries risk—so we use local exhausts at transfer points, not just in the central production hall.

    Waste stream management matters to us and to every downstream buyer. Our process recovers mother liquors where possible, reclaims solvents, and neutralizes spent residues. Inspectors from regional environmental agencies drop in unannounced, and we welcome these checks. Open records demonstrate our commitment, and sometimes help us spot improvements we overlooked. Producing MAP Sulfate for decades has taught us that waste control isn’t just a legal obligation—it reflects pride in chemical stewardship.

    Innovation: Listening to Users, Improving Continuously

    As a manufacturing team, we never claim the chemistry itself is “finished.” We read academic literature, attend technical meetings, and share application reports with the photo and research community. This exchange means we redesign plant reactors, refine analytical protocols, and update the specifications we report. During the rise of digital imaging, demand from film users declined, but high-value archives, hospitals, and artists demanded MAP Sulfate with longer shelf life and tighter controls on trace contaminants. Collaborating with expert users gave us the confidence to invest in new dry-blend lines and recruit staff with hands-on photographic science backgrounds.

    Direct user feedback prompted us to develop low-dust, granulated forms and double-layer anti-moisture pouches. International customers who deal with weeks of container transport on the ocean contributed advice on optimal pack size and warning labels. It takes collaboration to generate the sort of chemical goods that enter global programs in art conservation and medical archiving. Our product development line never stops—because end uses evolve, and so must the base materials.

    Building Trust in the Knowledge Supply Chain

    Being a chemical manufacturer means more than filling orders. Some buyers depend on technical guidance as much as the product itself. We maintain archives of reference test methods: checking dissolved clarity, measuring iron by DCP, confirming sulfate by ion chromatography. With consistent lab testing, users know each drum performs the same as the last shipment. We support audits from government labs, multinational buyers, and public institutions—our records are open for technical review.

    We also work with logistics partners to cut risk in cold or wet climates. Each lot ships with full synthesis traceability, so customers can identify the source and conditions behind every kilogram. Problems sometimes reach us, and we answer frankly. If a delivery fails, we send technical support—not just a form apology. We find that mutual respect, even in error, forges long partnerships.

    MAP Sulfate: Looking at the Future, Driven by Experience

    Chemical production lines change with global shifts. New green chemistry guidelines from regulators ask for better solvent recovery and less energy use. Research institutions now inquire about renewable feedstocks and the sustainability of our waste streams. We see increasing requests for detailed impurity profiles, not just a pass/fail certificate. To serve these requirements, we run continuous process audits and work with trusted vendors who share our technical standards.

    Some customers pursue next-generation developer systems, stretching the capabilities of MAP Sulfate into digital hybrid workflows, historic process restoration, or niche antioxidant blends. As demand shifts, we adjust our schedules, raw material reserves, and documentation protocols to keep up. Internally, we also pilot new reactor designs, test greener surfactants, and survey best practices from the global fine chemicals trade. Experience tells us that staying tuned to user needs matters as much as technical metrics printed on a label.

    Why End-Users Stay with Proven Manufacturers

    Buyers today face a crowded field of agents, with bulk brokers, traders, and web-based resellers offering inconsistent MAP Sulfate at prices that often defy production cost realities. We know the appeal of cut costs, but also see the resulting quality complaints: unexplained precipitation, gray discoloration, and unreliable shelf life that threaten entire production runs. Over decades of practice, we have learned that direct communication, deep process knowledge, and full transparency keep trusted users coming back.

    From local photography clubs to global archiving projects, users share one thing: a need for results that match the last batch, without surprises. Our plant workers, lab chemists, and packaging crews all share this same aim. Our business aim is steady reliability. Clear, open channels for technical support and documentation make that possible, turning anonymous orders into lasting partnerships.

    Final Thoughts from Decades of Manufacturing

    Manufacturing MAP Sulfate has taught us the value of hands-on expertise, rigorous feedback, and honest conversations at every stage. Each kilogram contains the story of every improvement and every customer report over decades. Staying committed to technical excellence, process safety, and sustainable production lets us supply a trusted product that supports essential industries. Direct experience on the plant floor shapes what we do—and the trust placed in our product every day shows us that those details matter.