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4-Methyl-5-Vinylthiazole

    • Product Name 4-Methyl-5-Vinylthiazole
    • Alias 4-methyl-5-ethenyl-1,3-thiazole
    • Einecs 222-449-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    914808

    Name 4-Methyl-5-Vinylthiazole
    Cas Number 63500-19-2
    Molecular Formula C6H7NS
    Molecular Weight 125.19 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 182-184°C
    Density 1.10 g/cm3
    Refractive Index 1.564
    Flash Point 70°C
    Purity ≥98%
    Solubility Slightly soluble in water, soluble in organic solvents
    Smell Roasted, nutty, meaty aroma
    Storage Temperature 2-8°C
    Ec Number 405-060-9
    Pubchem Cid 94154

    As an accredited 4-Methyl-5-Vinylthiazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams of 4-Methyl-5-Vinylthiazole; labeled with hazard information and lot number, securely sealed.
    Shipping 4-Methyl-5-Vinylthiazole should be shipped in tightly sealed containers, clearly labeled as a chemical substance. It must be protected from moisture, heat, and direct sunlight. Ensure compliance with relevant transport regulations, using appropriate packaging and cushioning to prevent leakage or breakage during transit. Handle and store in accordance with safety guidelines.
    Storage 4-Methyl-5-vinylthiazole should be stored in a cool, dry, and well-ventilated area away from sources of ignition and incompatible materials, such as strong oxidizers. Keep the container tightly closed, protected from light, heat, and moisture. Store under inert atmosphere if possible to prevent degradation. Ensure proper labeling and secondary containment to prevent accidental leaks or spills.
    Application of 4-Methyl-5-Vinylthiazole

    Applications of 4-Methyl-5-Vinylthiazole in Industrial Manufacturing

    4-Methyl-5-Vinylthiazole has established its role in specialized industrial applications due to its distinct aromatic and sulfur-containing structure. Our direct manufacturing involvement ensures consistent supply and technical guidance for integration into controlled downstream production processes. Below we detail dedicated end use scenarios supported by validated operational protocols and industry regulations.

    1. Food Flavors Manufacturing

    Food ingredient producers incorporate this molecule as a high-impact flavoring agent for processed meat, savory seasonings, and snack flavor bases. Its thiazole backbone delivers specific roasted-nut and meaty sensory nuances, with precise dosing and traceability enforced throughout liquid compounding, oil-based blending, or spray-dried flavor encapsulation lines. Users must ensure all batch declarations and residue monitoring comply with stringent food safety management systems in global markets.

    Industry compliance standards

    • FAO/WHO JECFA food additive evaluations
    • EU Regulation (EC) No 1334/2008 on flavorings
    • 21 CFR 172.515 (FDA, artificial flavorings regulation)
    • FSSC 22000-certified food safety programs

    Typical usage ratio

    • 0.1–5 ppm in final food application, with higher inclusion (up to 50 ppm) in flavoring concentrate depending on intended flavor strength and regulatory limits per country; processing method, matrix fat content, and thermal load affect dosage optimization.

    Downstream process integration

    • Added at blending or mixing stages for compound flavors; can be dissolved in carrier solvents before dry or wet granulation; inclusion timing varies between liquid emulsion or post-drying flavor system assembly.

    Final product types

    • Savory seasonings (gravy, bouillon, instant noodles powders)
    • Flavor cubes and pastes
    • Processed meat flavor blends for snacks
    • Ready-made meal and canned food aromas

    2. Tobacco Product Flavoring

    Manufacturers of reconstituted tobacco sheets, roll-your-own blends, or cigarette casing topnotes utilize this compound for its ability to impart cured, toasted, and nutty flavor notes. Industrial scaling requires careful atomization and infusion during casing formulation to avoid over-dosage and off-notes, and to comply with legally defined maximum inclusion levels and product labeling obligations.

    Industry compliance standards

    • European Tobacco Products Directive (2014/40/EU)
    • US FDA Tobacco Control Act (ingredient reporting, GRAS substances)
    • ISO 13276:2012 – Requirements for flavoring ingredients
    • Canadian Tobacco Reporting Regulations (SOR/2000-273)

    Typical usage ratio

    • 1–30 ppm in finished tobacco blend, with actual dosages set by technical trials and end-market flavor profile requirements; concentration may further adjust for blended or sheet reconstituted tobacco manufacture.

    Downstream process integration

    • Incorporated at liquid casing or sauce preparation stage, then applied by spraying onto cut or shredded leaf using controlled atomizing equipment before subsequent drying and mixing.

    Final product types

    • Flavored cigarette tobaccos
    • Pipe and rolling tobacco blends
    • Reconstituted tobacco sheets
    • Cigar and cigarillo filler material

    3. Pet Food Palatant Formulation

    Pet nutrition manufacturers add this component to palatant systems targeting enhanced aroma and acceptance for dry kibbles or wet feeds. The sulfur ring contributes critical top-notes in animal and poultry characterizations, with implementation strictly supervised by both veterinary safety boards and major global pet brand quality systems. R&D teams work closely with sensory evaluation panels to fine-tune flavor delivery while fulfilling analytical verification protocols.

    Industry compliance standards

    • AAFCO Official Publication (US pet food flavor ingredient approval)
    • Regulation (EC) No 1831/2003 (EU feed additive authorization, flavoring compounds)
    • FEDIAF Code of Good Labeling Practice
    • ISO 22000 Food Safety Management for pet food plants

    Typical usage ratio

    • 0.3–10 ppm in finished pet food; allows upward adjustment to 50 ppm in liquid seasoning bases or palatant slurry, dependent on species target and base formulation (protein or grain base).

    Downstream process integration

    • Mixed into oil-based palatant blends prior to extrusion coating or spray application onto feed kibble; optionally incorporated in digest pre-ripening tanks for canned or fresh pet food aromatization.

    Final product types

    • Coated dry kibbles for dogs and cats
    • Wet pet food pouches and tins
    • Treats and snack sticks
    • Vitamin and functional supplement chews

    4. Aroma Chemicals for Fragrance Blending

    Manufacturers compounding functional fragrances for household air fresheners, fine perfume bases and consumer sprays value this molecule as an effective impact note in roasted, nutty, and animalic compositions. It demands controlled storage and handling in accordance with fragrance industry output requirements while maintaining necessary documentation for regulatory audits and raw material traceability in finished blends.

    Industry compliance standards

    • IFRA Standards (International Fragrance Association Quantitative Restrictions)
    • EU Cosmetics Regulation 1223/2009 (fragrance component reporting)
    • ISO 9235:2013 (Aromatic raw materials)
    • Global Product Safety and Toxicology Assessments for consumer fragrances

    Typical usage ratio

    • 0.01–2% in fragrance oil concentrate; the actual ratio aligns with IFRA limits and desired intensity in end use (air care, detergents, personal care), and is adjusted through pilot batches to optimize sensory impact without exceeding established thresholds.

    Downstream process integration

    • Added to perfume compound blend during oil phase creation, before solubilization in solvents or encapsulation for spray-dried or gel-based fragrance systems; subsequent QC ensures batch consistency and conformance with declared levels.

    Final product types

    • Room sprays and air fresheners
    • Liquid and gel odor counteractants
    • Scent boosters in laundry care
    • Home and professional fragrance diffusers
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    Certification & Compliance
    More Introduction

    4-Methyl-5-Vinylthiazole: Straight from Our Manufacturing Floor

    What Makes Our 4-Methyl-5-Vinylthiazole Stand Out

    Every batch of 4-Methyl-5-Vinylthiazole coming out of our production lines carries our signature approach—tight process control, real experience behind the equipment, and a clear commitment to real-world applications, not just lab-based perfection. Over the years, we've listened closely to flavorists, specialty chemical users, and technical development teams who asked for reliability over vague promises. That is why production here doesn't just focus on analytical purity, but on repeatable consistency and transparent results, batch after batch.

    Why 4-Methyl-5-Vinylthiazole Matters to Industry

    4-Methyl-5-Vinylthiazole grabs attention from food and beverage developers, perfumers, and chemical researchers for good reason. This compound brings a roasted, nutty aroma to food formulations, especially in applications where traditional high-temperature processing would hurt functional properties of other flavor ingredients. We aren't just talking about textbook flavor; we see how actual projects in roasted nut, bakery, and snack foods perform better when developers have access to a dependable, high-purity vinlythiazole. Our engineers have adjusted our process to avoid lingering off-notes and residual solvents that could drag down sensory scores or cause regulatory challenges. This focus on the user experience, not just the molecule itself, sets the tone in every drum and flask we fill.

    Specifications as Built in Our Facility

    What comes out of our reactors matches tight specifications: colorless to light yellow liquid, robust stability under recommended storage, and a GC area purity above 98%. Water content stays low due to advanced drying steps, and our team moves quickly from synthesis to purification to reduce the window for air or light exposure—two factors that play havoc with thiazole derivatives. We've eliminated points in the process where chlorinated byproducts tend to sneak in, after noticing minor peaks in early GC-MS testing when we scaled up from pilot to production. That kind of detail work stems from walking the shop floor and getting input from the technicians handling downstream columns and distillation units, not from following a cookbook approach.

    Model and Packaging Details: Practical Solutions for Real Use

    Our main model, MVThz-4M5V, is packed to fit labs scaling up deliveries as well as food processors ordering by the pallet. We use glass containers for small-run testing and high-integrity aluminum bottles or HDPE drums for industrial users. We personally check for compatibility with automated dosing systems—labels dissolve in water-based cleaning stations, caps use tamper-evident designs to help with traceability, and drums stack well on standard shipping pallets without risk of puncturing. Experience tells us that a great molecule is no help if it evaporates or absorbs moisture on the shelf, so air-tight seals and genuine barrier materials matter as much as anything inside the flask.

    How 4-Methyl-5-Vinylthiazole Compares to Standard Compounds

    You might run into thiazole derivatives with similar backbone structures in the chemical catalog or flavor standards list. What typically gets lost in translation is the difference a vinyl group in the five position makes compared to plain 4-methylthiazole or unsubstituted thiazole. On the manufacturing floor, this adjustment means slightly tighter temperature and pressure control during synthesis, and a tendency for isomer formation if you slack off during workup. Some suppliers will blend lower-cost side products and stamp it as "food-grade." We've tested samples from around the world—these offcuts may slip by on paperwork but stand out on the GC trace and come through as haze or bitter spike in finished food systems. We hold the material fraction to a narrow isomer ratio, which means flavor results show minimal variation from lot to lot.

    Real Ingredient Impact for Developers

    Users in our customer network repeatedly mention the complex profile this molecule gives when blended at low concentrations. It rounds out mocha, coffee, and roasted meat flavors, sometimes serving as the subtle background layer that never jumps out in a taste panel but makes the finished product richer and longer-lasting. Processing experience tells us that 4-Methyl-5-Vinylthiazole survives short-term baking or roasting with little breakdown, unlike fragile lactones or pyridines that burn off quickly. That means food scientists can formulate robust profiles without switching out ingredients for each heating step. We encourage pilot batches, and our technical support always wants to see side-by-side results in finished food formats—the best work comes from active feedback, which we treat as more valuable than a printed spec sheet.

    Typical Applications: Reality-Driven Choices

    Our clients work in bakeries, snack food systems, sauces, savory seasonings, pet food, and beyond. We see the compound pop up in coffee, roasted nuts, and even meaty flavors for vegetarian and vegan recipes. Perfumers also use small amounts to lift nutty or roasted facets in fine fragrance, but most of our volume heads into food use. One takeaway from years of feedback: product managers often want more shelf life and resistance to high-temperature manufacturing. Our process keeps oxidative instabilities and acid-base degradants in check, which cuts down on off-flavors developing over time. We've taken those lessons and worked out ways to prevent the common "cardboard" or beany notes that show up when residual impurities sneak through.

    Quality Assurance Built on the Ground

    Quality for us is more than hitting a purity percentage on a printout. Each step in our workflow installs redundant checks: we run GC-MS not just at release but at every main hand-off point, and our staff looks for trace solvent signals long before the product reaches bottling. Teams sample each reactor output—actual people, not just remote-controlled samplers—and feed back early signals of any drift in reaction kinetics. We invested in closed-loop ventilation and air filtration above each reactor row after noting elevated sulfur counts in our air samples, a sign of micro-leakage that can affect thiazole stability. Field complaints from early years shaped our system into its current form; new trainees learn those backstories so that hard-won lessons don’t get lost.

    Handling, Storing, and Shipping: Experience in Motion

    Folks working with thiazoles often worry about odor transfer, volatility, and exposure. After years of freight headaches, we doubled down on packaging integrity by sourcing multilayer containers and making sure seals hold up both in tropical and cold chain conditions. Drums are lot-coded with ink resistant to most oils and detergents—needed after trouble with unreadable labels in a past sea shipment. Shipments head out under strict loading times, especially for export, to avoid daylong holds that can raise container temps and risk the tight sulfur profile we've worked so hard to protect. On-arrival testing at key customers’ facilities keeps us honest, and we invite users to conduct blind fingerprinting against competitor materials.

    Worker Safety and Exposure Concerns

    We've set up closed transfer systems in manufacturing not just because of regulations but because we've dealt with enough accidental skin or vapor exposure events to know real risk exists. We run live air monitors during bulk transfers, and our building-wide ventilation deals with trace odors that can easily build up to irritating levels. Training matters too: new employees learn the process hazards in context, right on the line, not just from PowerPoint slides. Over time we cut process incidents by investing in better gaskets, automatic cap-tightening, and an internal incentive program for finding small leaks and reporting near-misses before they become problems. These practical safety steps stem from direct experiences—not just regulatory compliance.

    Documented Traceability and Regulatory Confidence

    Traceability remains built into every production record. End-users need more than just a batch number and a certificate of analysis to satisfy auditors. On each shipment, we deliver digital documentation showing time-stamped process data, chain-of-custody signatures, and detailed impurity tracking. Our food users benefit from full allergen and GMO review workflows; those in fine chemicals get material origin reports plus impurity mapping. As national and international rules shift, we stay tuned in to both flavor and chemical safety authorities, partnering with compliance organizations to keep clear of gray areas. In the rare event of a recall or a customer question, retrieval speed makes all the difference—we’ve streamlined our data retrieval so recall lookups take minutes, not days.

    R&D Support and Application Guidance Based on Real Cases

    Users face actual hurdles, like scaling up kitchen prototypes to plant-size runs or blending with complex ingredient lists where interactions aren’t obvious on paper. Our technical team works shoulder-to-shoulder with clients on real trials—setting up controlled bake-offs, providing heat stress data, and troubleshooting flavor masking or blooming. Over the years, this hands-on work led us to tweak both the synthetic route and the post-purification steps to address specific pain points reported by end-users, such as haze formation or reaction with certain storage plastics. We’ve even rebuilt our sample program to allow for quick-turn testing batches sized for specific pilot lines, rather than forcing standardized drums on developers just starting out.

    Reducing Environmental and Operational Waste

    Running a thiazole plant invites questions about environmental performance. We've listened to local regulators and in-house engineers to cut water and solvent usage, dialing in closed-loop recovery and treating exhaust more aggressively after identifying residual sulfur signals outside original factory limits. Our waste stream management uses real-time sensors to catch off-spec discharges and route them to safe treatment or reprocessing. Years ago, we faced complaints about strong odors reaching nearby businesses—so we invested heavily in upgraded scrubbing towers and real-time leak alarms on all high-volume lines. Any manufacturer worth their salt knows environmental shortcuts end up as uncomfortable visits from inspectors or even angry neighbors, so we keep performance high not just for compliance but because we work in these communities too.

    Supporting Long-Term Customer Partnerships

    More than a few of our repeat customers started with small projects, where a novel roasted note or nutty edge was the missing ingredient in a new product launch. These partners came back for larger volumes, and over time, our teams worked through critical scale-up issues together—sometimes at odd hours across time zones or in person on customer lines, troubleshooting in real time. We’ve learned that strong partnerships grow from attentive batch tracking, honest answers to tough technical questions, and a willingness to adjust specs to match a new regulatory environment or production limit. Requests for long-term supply stability taught us to over-invest in reserve capacity and raw material auditing, so our partners never find themselves stuck without a supply chain solution.

    Distinguishing True Manufacturing Expertise from Repackaging

    Industry veterans can spot the difference between a genuine producer’s material and something disguised by a middleman. We show process documentation during audits and allow site visits with minimal notice. We regularly see traders advertising material that only loosely matches flavor profiles or contains unlisted impurities caught by diligent flavorists or regulatory specialists. Over time, labs and product developers learn to separate routine catalog offerings from direct-from-plant materials that hold up to repeated use. References from seasoned formulators and technical reviewers reinforce our model—it’s about shared experience, not just compliance certificates.

    Continuous Improvement as a Real-World Practice

    Change for us doesn't just come from near-miss events, but also from deliberate collaboration with frontline process staff, customer feedback loops, and updates from field users experimenting with new flavor systems. Early process lines suffered from fouling at filter stages; through iterative adjustments and staff workshops, we retooled our purification strategy and nearly eliminated this recurring downtime. Maintenance crew advice led us to choose more robust pump seals that cut downtime, and regular cross-functional team meetings ensure that manufacturing tweaks align with both R&D goals and quality assurance. From ingredient performance in end uses to upstream material handling, every improvement run reflects on actual user outcomes, not just technical process diagrams.

    Future Focus: Scaling Responsibly

    Demand for traceable and high-quality 4-Methyl-5-Vinylthiazole keeps growing, especially as more markets shift toward authentic roasted and nutty flavor profiles without hidden chemical baggage. We're working to build out additional process lines for greater capacity and redundancy, balancing investment in automation with the skilled craft needed for these sulfur-nitrogen specialties. Plans to expand include co-developing application-specific variants, responding to direct customer requests for tighter flavor or performance bands. Sustainable sourcing, tighter emission controls, and regular upgrades in line with evolving safety and food laws are all on the horizon. Our goal remains to supply materials that give real results in the world’s food and fragrance launches—not just to tick boxes in a catalog.

    The Manufacturer’s Perspective—What Sets Us Apart

    Anyone relying on 4-Methyl-5-Vinylthiazole deserves more than just a label and a spec sheet. From raw material stewardship through final drum dispatch, we own the process and stand behind every shipment. Years of direct feedback, practical improvements, and collaborative troubleshooting built an approach focused not just on today’s needs but also tomorrow’s regulatory and market realities. This material thrives in real-world systems because it’s been engineered by those who see—and solve—the process and application challenges every day. That’s our pledge as a manufacturer, and the reason our partners continue to trust us batch after batch, project after project.