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HS Code |
319035 |
| Product Name | 4-(Hydroxymethyl)Benzoic Acid |
| Cas Number | 874-90-8 |
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Appearance | White to off-white solid |
| Melting Point | 200-202 °C |
| Solubility In Water | Slightly soluble |
| Boiling Point | 443.3 °C at 760 mmHg |
| Density | 1.39 g/cm3 |
| Purity | Typically ≥98% |
| Pubchem Cid | 14638 |
| Synonyms | p-Carboxybenzyl alcohol |
| Smiles | C1=CC(=CC=C1CO)C(=O)O |
| Storage Temperature | Store at 2-8 °C |
| Ec Number | 212-869-5 |
As an accredited 4-(Hydroxymethyl)Benzoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 g of 4-(Hydroxymethyl)Benzoic Acid is supplied in a sealed, amber glass bottle with a secure tamper-evident cap. |
| Shipping | 4-(Hydroxymethyl)Benzoic Acid is shipped in tightly sealed, chemical-resistant containers to prevent contamination and moisture absorption. It is packaged according to regulatory guidelines for safe transport of chemicals. Appropriate labeling, including hazard information, ensures safe handling during shipping. The product ships via ground or air, depending on destination and regulations. |
| Storage | 4-(Hydroxymethyl)benzoic acid should be stored in a tightly sealed container, protected from light and moisture, and kept in a cool, dry, well-ventilated area. Avoid direct sunlight, heat, and sources of ignition. Store separately from incompatible substances such as strong oxidizers and bases. Proper labeling and adherence to local chemical safety regulations are essential for safe storage. |
Applications of 4-(Hydroxymethyl)Benzoic Acid in Industrial ManufacturingAs an established manufacturer of 4-(Hydroxymethyl)Benzoic Acid, we supply this intermediate to multiple downstream industries where it supports production efficiency, process stability, and product function. Below are distinct industrial applications, highlighting the integration of our material in real-world manufacturing environments. 1. Pharmaceutical Intermediates for Active Pharmaceutical Ingredients (APIs)Our material enters the pharmaceutical synthesis workflow as a key intermediate for building selective COX-2 inhibitors, antihypertensive agents, and antimicrobial drugs. Downstream partners integrate this compound in controlled batch reactions due to its stable carboxyl and hydroxymethyl functionality. During multi-step synthesis, the product supports precision modifications and enables robust API yields. Validation is critical; thus, compliance with rigorous international pharmacopoeias and trace impurity control holds priority throughout all process stages. Industry compliance standards
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2. Polyester and Polyamide Polymerization AdditivePolymer producers use this compound as a chain terminator and structural modulator in specialty polyesters and copolyamides. The hydroxymethyl group improves branching and modulates crystallinity, influencing polymer thermal/mechanical behavior. Dosing relies on targeted molecular weight distribution and desired end-use performance. This additive benefits bottle-grade PET and film production, facilitating improved impact resistance and process stability. Production lines with continuous polymerization units benefit from tight QC and material flow monitoring to ensure product uniformity. Industry compliance standards
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3. Synthesis of UV-Absorber and Stabilizer AdditivesAdditive producers rely on this compound as a functional building block in the manufacture of UV-absorbing chemicals for coatings, plastics, and elastomers. The benzoic acid core provides a stable aromatic scaffold, while the hydroxymethyl group permits selective etherification or esterification, maximizing compatibility in polymer matrices. By selecting appropriate conversion steps, formulators tune UV absorption peaks and weathering resistance, critical for outdoor use materials where prolonged exposure to sunlight occurs. Industry compliance standards
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4. Liquid Crystal Intermediate for Display MaterialsManufacturers of display and electronic films employ this material in the fine chemical synthesis of advanced liquid crystal monomers. Its distinct aromatic-hydroxymethyl structure fits strict purity requirements for electronic applications, with careful attention to trace ionic and metal content. Downstream teams use it in Friedel–Crafts or esterification reactions to build rod-like mesogens, vital for stability and contrast in LCD and OLED applications. This application demands best-in-class trace analysis and batch traceability from upstream suppliers. Industry compliance standards
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5. Active Ingredient in Specialty Corrosion InhibitorsProducers of corrosion inhibitor formulations utilize this compound in waterborne system blends for industrial cooling water, boiler, and metal surface treatments. Formulators leverage its functional group reactivity to bind metal ions and form passivation layers, especially in systems handling high temperature and variable pH. Consistent feedstock quality, low volatility, and traceability for environmental compliance mark critical requirements in this market segment. Material dosing and blend ratios adjust according to metal type and fluid conditions on site. Industry compliance standards
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In the realm of specialty chemicals, 4-(Hydroxymethyl)Benzoic Acid stands out for its clear role in advancing fine chemical applications. We have honed our approach toward producing this compound, identified by its chemical formula C8H8O3, with a sense of practical responsibility. Known for its consistent purity and white crystalline nature, our material reflects our compliance with industry standards and thorough, transparent quality control.
Each batch of our 4-(Hydroxymethyl)Benzoic Acid reflects years of continuous improvement. The product shows a melting point typically around 143-146°C, and its structure contains both a carboxyl group and a benzylic alcohol. Through this combination, it provides a flexible synthetic handle for chemical transformations, serving both established and emerging needs in pharmaceutical intermediates, photographic chemicals, and polymer modifiers.
Tight control over production means fewer worries about batch-to-batch variability. The facility maintains closed-systems during synthesis and handles the substance in ways that safeguard both the environment and downstream users. Our technicians rely on validated methods, such as HPLC and NMR, to check for byproducts and confirm purity. Each kilo provides a reliable starting material for downstream chemical syntheses, because we control every stage, from raw benzoic acid checking to thorough purification of the final solid.
Years of working with 4-(Hydroxymethyl)Benzoic Acid have taught us it can demand patience. Synthesis requires precise conditions during the hydroxymethylation step—temperature, pressure, and reagent quality all leave their mark. The end product rewards this patience. When used as a building block for pharmaceuticals, protective groups attach easily at the hydroxymethyl position. When entering polymer science, the benzylic alcohol gives useful cross-linking potential. Researchers have found it especially helpful for preparing benzyl ethers and esters that need stability and selective cleavage.
Nothing replaces the value of direct knowledge gained during every production run. Every customer order carries reminders of the practical challenges in laboratories and production plants: needs for reproducible purity, clear origin traceability, and dependable response to technical questions. Distributors and resellers sometimes obscure these details—or even introduce delays as simple questions pass through too many hands. Manufacturers have to offer more: secure material that supports customers’ ability to meet regulatory milestones, pass audits, and formulate with confidence.
Large energy and process investments go into reliably producing specialty benzoic acid derivatives. That’s why our direct communication with chemists and formulators sharpens our attention to potential process issues. If a customer suspects a contamination risk, samples from our retained lots come under scrutiny to answer these questions directly, not through intermediaries. This approach minimizes downtime and gives researchers and manufacturers direct insight when scaling up or troubleshooting.
Every shipment of 4-(Hydroxymethyl)Benzoic Acid leaves our facility with a set of intended roles in mind. The primary use appears in pharmaceutical R&D, as teams design active ingredients, prodrugs, or stable intermediates based on its structure. Our product often enters into condensation reactions or selective oxidations, supporting the synthesis of more elaborate molecules. Academics and industrial chemists both demand material that reacts predictably and withstands storage.
Polymer applications reflect a different side of the product. Here, the introduction of a hydroxymethyl group not only adjusts molecular weight and crystallinity but also enables specific compatibility for performance plastics. The carboxylic acid group, alongside the benzylic alcohol, means resin formulators can tune crosslink density to a degree not found in other benzoic acid variants.
Another set of end-users turns toward our 4-(Hydroxymethyl)Benzoic Acid for its role in producing high-performance esters and photosensitive intermediates. These applications demand trusted analytical support: consistent melting range, transparent impurity data, and responsive answers to all technical questions. As a firm producing at the source, we are able to align our analytical release criteria with customer-specific application needs.
4-(Hydroxymethyl)Benzoic Acid enters the landscape among a family of para-substituted benzoic acids. Compared to simple benzoic acid, the hydroxymethyl group contributes reactivity, allowing for further substitution or modification by standard organic synthetic steps. Alternate derivatives, such as 4-methylbenzoic acid (p-toluic acid), lack the accessible alcohol function, limiting their value as building blocks in many target molecules. Others, such as phthalic acids or more complex aromatic alcohols, introduce challenges with steric hindrance, solubility, or unmanageable side reactions.
Our experience working with these related compounds has highlighted the nuanced differences in downstream chemistry. With 4-(Hydroxymethyl)Benzoic Acid, the polarity and mild nucleophilicity of the alcoholic group allow selective protections or functionalizations. The molecular weight of 152.15 g/mol fits well for both small-scale and industrial protocols, and its crystalline solid form simplifies handling compared to viscous or hygroscopic analogs. This matters not just for bench chemists but for plant operators tasked with weighing out and dissolving the substance day after day.
Quality control routines go further with this compound than with more basic benzoic acids. Water content or trace metal impurities, which might be negligible in bulk chemicals, become essential data points. As a manufacturer, we provide these details up front, saving time for partner labs by eliminating downstream surprises. This readiness stands in contrast to material from resellers, where supporting data may not align with the requirements of regulated processes or custom synthesis work.
Chemicals like 4-(Hydroxymethyl)Benzoic Acid reward careful process engineering. We have encountered bottlenecks from hydroxyalkylation steps and learned to favor a more gradual approach—slower addition, tight thermal management, finer filtration. Direct observations in our plant have shown that even slight changes in temperature ramp rates or catalyst selection can produce different impurity patterns, leading us to adapt monitoring protocols.
Handling and packaging require special consideration. Crystalline integrity affects dissolution rates during customer’s formulations. Agglomerates or fines can trouble both laboratory balances and industrial feeders. Our technicians manage this by controlling humidity and static during the filling process, using lined drums or sealed bags as needed. Shipment histories indicate that attention to bulk density and tamper evidence reduce risks of storage-related quality drift.
A chemical’s value involves more than its synthetic versatility—compliance demands increase each year. Researchers and manufacturers in all regions expect supporting documentation: REACH registrations, clear GHS labeling, up-to-date SDS, and lot-level traceability. Every batch leaving our gates comes with these supports, prepared not by template, but by people directly involved in production. This instills confidence across technical, commercial, and regulatory teams at our customers’ sites.
Our site teams manage waste and emissions streams with the same thoroughness applied to product quality, capturing every step and minimizing risks to health and safety. Staff receive continuous training on handling benzoic acid derivatives, so daily plant routines and emergency response drills reflect current best practices. We carry decades of embedded knowledge, so customers know the human stories and technical vigilance that stand behind every pallet or drum.
In recent years, inquiries about product carbon footprint and lifecycle data have placed new expectations on manufacturers. We recognize these priorities. Where possible, we have substituted greener reagents or energy sources, publishing updates as improvements become validated. Open sharing of environmental metrics reflects genuine partnership with researchers focused on sustainable chemistry.
We have noticed that research on 4-(Hydroxymethyl)Benzoic Acid grows year after year. Innovative medicinal chemists use it for smart drug linkers; material scientists exploit the balance of reactivity and stability in new coatings or sealants. Sometimes requests arrive that challenge what we thought possible—tailored particle size, customized drying, special packaging, or extended stability trials. Direct involvement in the process helps us work alongside customers, not just as suppliers, but as stakeholders in their development projects.
Extensive technical records let us quickly support novel applications or qualification runs for medical and high-performance sectors. Teams here maintain open channels with customers, reviewing feedback and supporting trouble-shooting. Many customizations originate from such exchanges: a tightened specification, a more robust container for overseas shipment, an adjusted delivery frequency based on a new project’s needs. None of this would emerge from a pure trading operation, only from manufacturer’s continuous investment in capability and relationship.
In global markets, volatility and uncertainty test the discipline of supply chain management. Our decades of experience in specialty chemical production mean deeper reserves of raw materials, agile scheduling of plant shifts, and plans ready to secure consistent material during interruptions. Direct manufacturer supply insulates end-users from sudden shortages or extended lead times. These supply reliability considerations gain value in regulated industries, where changes in input chemicals can set back projects and increase complexity.
Years watching shipments move from plant to lab bench to industrial reactor underscore the importance of product stewardship. Our technical support team offers on-the-ground advice for avoiding cross-contamination, clumping, or unplanned exposure. While 4-(Hydroxymethyl)Benzoic Acid stores stably in cool, dry conditions, subtle factors—ambient humidity, container permeability, or even variation in warehouse temperature—alter shelf life and ease of use. Since every gram we ship flows from line operators and analysts who see the product daily, practical storage and handling tips arrive rooted in direct experience, not theory.
Plant visits and customer audits provide further learning. Engaged end-users often present unique questions about compatibility with solvents, blends, or dosing systems. Our technical team supports studies on solubility, reactivity with specific process intermediates, or compatibility with commonly used stabilizers, drawing on historical plant data and literature tracking.
The field of benzoic acid chemistry continues to change. New reaction pathways and green technology norms drive a steady evolution of expectations from customers and regulators. While today much discussion centers on medicinal and polymer chemistry, tomorrow’s uses might emerge from electronics, bio-derived plastics, or enhanced adhesives. Our facility adapts as requirements evolve. Years of building in-house expertise and cross-training chemists and operators provide a workforce prepared to fine-tune the product whenever novel synthesis or analysis methods demand different purity or analytical controls.
Suppliers without direct manufacturing face built-in gaps—longer timelines to adapt, less certainty about the nuances that separate acceptable from exceptional product quality, less flexibility when customers need adjustments. Chemical manufacturing, especially for specialty compounds like 4-(Hydroxymethyl)Benzoic Acid, asks for adaptability and thorough understanding as much as technical skill.
Every day our manufacturing team reviews new literature, process patents, and application reports. Chemistry never stays still. Direct engagement with product gives us an edge in bringing sustainable, safe, and high-quality 4-(Hydroxymethyl)Benzoic Acid to innovative end-users, whether in pharmaceuticals, advanced materials, or academic research.
Manufacturing 4-(Hydroxymethyl)Benzoic Acid reliably is about more than having the right reactors and analytics. It demands responsive and skilled people, experienced in handling the special needs of customers working on demanding projects. Many collaboration and innovation stories begin with a simple request for a certificate or a technical explanation and grow into enduring partnerships built on direct manufacturer access.
As we look forward, the mindset guiding our work will remain constant—the readiness to answer direct questions, to take feedback into our laboratory and plant, to share lessons learned, and to bring value through more than just a bottle of chemical. From our factory floor to your lab bench, 4-(Hydroxymethyl)Benzoic Acid continues to support the advancement of science and technology, driven by the dedication of experienced hands and the enduring quest for better solutions.