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4-Hydroxyheptanophenone

    • Product Name 4-Hydroxyheptanophenone
    • Einecs 242-039-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    571748

    Chemicalname 4-Hydroxyheptanophenone
    Casnumber 19715-19-6
    Molecularformula C13H18O2
    Molecularweight 206.28 g/mol
    Appearance White to off-white solid
    Solubility Soluble in organic solvents such as ethanol, methanol, DMSO
    Structuralformula C6H5CO(CH2)3CH(OH)CH2CH3
    Iupacname 1-(4-hydroxyheptan-1-yl)phenone
    Purity Typically ≥97%
    Storagetemperature Store at 2-8°C
    Synonyms 4-Hydroxy-1-phenylheptan-1-one

    As an accredited 4-Hydroxyheptanophenone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for 4-Hydroxyheptanophenone (100g) is a sealed amber glass bottle with a tamper-evident cap and chemical hazard labeling.
    Shipping 4-Hydroxyheptanophenone is shipped in tightly sealed, chemical-resistant containers to prevent contamination and leakage. It is handled as a hazardous material, requiring appropriate labeling and documentation in accordance with international regulations. The product is protected from light, moisture, and extreme temperatures during transit to maintain stability and safety.
    Storage 4-Hydroxyheptanophenone should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances. Protect it from direct sunlight, moisture, and strong oxidizers. Ensure that the storage area is equipped with proper spill containment and labeled appropriately to prevent accidental exposure or contamination.
    Application of 4-Hydroxyheptanophenone

    Applications of 4-Hydroxyheptanophenone in Industrial Manufacturing

    As the original manufacturer of 4-Hydroxyheptanophenone, we supply this specialty intermediate directly to industrial partners for integration into advanced synthesis processes. The following application scenarios reflect established markets and validated supply chains, selected on the basis of consistent demand and proven technical feasibility within each field. Each scenario below details integration methods, formulation ratios, relevant regulatory frameworks, and the end products manufactured downstream.

    1. Synthesis of Pharmaceutical Intermediates for Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

    Pharmaceutical synthesis applications utilize 4-Hydroxyheptanophenone as a controlled ketone intermediate in the multistep synthesis pathway of select arylalkanoic acid derivatives. This compound enters the route following aromatic functionalization and precedes further oxidation, serving as a pivotal structure for drug candidates in the anti-inflammatory and analgesic medication segment. Manufacturers adjust the quantity based on molar conversion and solvent volume during the batch reaction—parameters mandated by GMP and international pharmacopoeial standards.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients
    • 21 CFR Part 211 (US cGMP for Finished Pharmaceuticals)
    • European Pharmacopoeia Monograph 2.6.16
    • WHO Good Manufacturing Practices (Global)

    Typical usage ratio

    • 0.5% – 2.5% by total batch weight, calculated depending on target yield and specific synthetic route limitations, as well as the reactivity index of the downstream conversion.

    Downstream process integration

    • Charged into the primary condensation or Friedel–Crafts acylation step in the API intermediate sequence, typically dissolved in aprotic solvents under controlled temperature and agitation prior to oxidation and purification stages.

    Final product types

    • Ibuprofen intermediates
    • Naproxen intermediates
    • Ketoprofen precursors
    • Custom arylpropionic acid drug intermediates

    2. Fragrance and Flavor Synthesis (Fine Chemicals)

    Producers in the aroma chemical sector harness the reactive hydroxyketone group for constructing elongated aromatic compounds vital in crafting musk and woody base notes. The material’s unique carbon backbone and functionalization points support selective alkylation and controlled reduction, which define the sensory profiles of specialty perfumes and flavors. Process engineers adjust the added proportion to balance product intensity and olfactory thresholds, strictly following safety and purity requirements enforced globally for consumer fragrances and food additives.

    Industry compliance standards

    • IFRA (International Fragrance Association) Standards
    • EU Regulation (EC) No 1223/2009 for Cosmetic Products
    • US FDA 21 CFR 172.515 (Flavoring Agents for Food)
    • ISO 9235:2021 (Aromatic raw materials)

    Typical usage ratio

    • 0.1% – 1.0% by formulation, with precise ratios determined by scent diffusion requirements and blending protocols, commonly optimized via pilot batch sensory panels.

    Downstream process integration

    • Incorporated during initial aroma compound synthesis—usually entering the alkylation or reduction step after initial aromatic assembly, monitored for purity, and then followed by distillation or fractional crystallization.

    Final product types

    • Fine fragrance bases for eau de parfum
    • Flavor concentrates for beverages and confections
    • Complex musk and woody note aroma chemicals
    • Household fragrance formulations (detergents, fabric softeners)

    3. Advanced Organic Pigment Intermediates

    Specialty pigment manufacturers utilize this hydroxyketone structure in the design of high-performance colorants for plastics and coatings. By leveraging its reactivity in condensation and coupling reactions, producers generate advanced diaryl compounds suitable for pigment molecules requiring thermal and light stability. Material dosing aligns closely with chromatic strength targets and dispersion requirements set by downstream resin or polymer system compatibility and environmental compliance norms.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 – SVHC assessment
    • EN 71-3:2019 (Safety of toys — migration of certain elements)
    • ISO 1248:1974 (Pigments — specifications and test methods)
    • ASTM D5630-13 (Ash Content in Plastics)

    Typical usage ratio

    • 0.3% – 1.5% by weight in pigment synthesis batches, ratio fine-tuned for molecular compatibility, tinting strength, and specific performance requirements in high-durability pigment classes.

    Downstream process integration

    • Added into the initial condensation reaction for pigment intermediate formation, typically under controlled temperature and pressure, followed by isolation and surface modification prior to pigment finishing and grinding.

    Final product types

    • High-strength organic pigments for engineering plastics
    • Weather-resistant architectural coatings
    • High-fastness printing inks
    • Color masterbatches for compounders

    4. Photoinitiator Precursor for UV-Curing Systems

    Manufacturers of photoinitiators employ this building block to produce advanced diaryl ketones for UV-cured coatings and inks. Strategic introduction of the hydroxyheptanophenone enables modifications at the ketone function, directly influencing absorption wavelength and crosslinking efficiency for downstream acrylate or methacrylate systems. Typical factory-scale processes involve close QC monitoring on addition rates and impurity handling, ensuring output aligns with industrial photopolymer norms and occupational health requirements.

    Industry compliance standards

    • ISO 9001:2015 (Quality Management Systems)
    • Restriction of Hazardous Substances (RoHS, EU Directive 2011/65/EU)
    • GHS (Globally Harmonized System of Classification and Labelling of Chemicals)
    • IEC 62471 (Photo-biological safety of UV sources)

    Typical usage ratio

    • 0.2% – 0.8% by overall photoinitiator batch weight; precise adjustments depend on targeted photoinitiator reactivity and solvent proportion adopted downstream in coating or ink production.

    Downstream process integration

    • Reacted during the initial ketone derivatization step for photoinitiator synthesis, followed by purification and concentration before delivery as a photoinitiator concentrate or blend for direct addition into UV-curable resin or ink systems.

    Final product types

    • UV-cured offset and flexo inks
    • Clear and pigmented UV coatings
    • Adhesive formulations for electronics
    • Optical fiber curing resins
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    Certification & Compliance
    More Introduction

    4-Hydroxyheptanophenone: A Practical Manufacturer’s Perspective

    Introduction to 4-Hydroxyheptanophenone—Experience from the Lab Floor

    Putting 4-Hydroxyheptanophenone into the hands of chemists, researchers, and product developers has taught us a lot about its real working value over the years. New molecules come through the pipeline all the time, but not every compound offers the clean, repeatable performance we see with this compound. Our synthesis team pays attention to its quirks—how it comes together, its reactivity, and where its structure fits into existing and emerging applications. Through hands-on production runs, QC evaluations, and routine conversations with process engineers, we reach conclusions that help users extract the most from its unique properties.

    How Our Production Approach Builds Reliable Product

    Manufacturing 4-Hydroxyheptanophenone brings together experience with acetophenones, skill in handling demanding temperature schedules, and a practical sense of batch consistency. Our reactors handle multi-step synthetic paths without introducing side impurities that can throw off downstream use. Years of troubleshooting reactions and interpreting chromatography data have shown us what works and what leads to stubborn contamination. It takes careful solvent management, crisp temperature control, and a sense for when a reaction is actually ready to work up, not just complying with a clock. Every kilogram comes from this continuous feedback loop between chemists and the process bay—a cycle grounded in repeated hands-on work rather than theoretical best-practices.

    Identifying Real-World Performance Markers

    In practical development environments, product lot performance matters more than lab-scale numbers. The real differentiator with our 4-Hydroxyheptanophenone springs from consistent melting profiles, truly low residual metal traces, and lot-to-lot color matched to strict in-house benchmarks. One can see the difference immediately: a clear, defined crystalline structure, minimal batch-to-batch variation, and a controlled proportion of the para versus ortho isomer. That structure ensures reactivity and allows our customers’ subsequent steps—be it acylation, alkylation, or further oxidation—to proceed without fiddling with purification.

    Molecular Characteristics Influencing User Outcomes

    4-Hydroxyheptanophenone features a hydroxy substitution on a heptanophenone backbone, combining a flexible aliphatic tail with a phenolic head. This makes it more polar than straight-chain heptanophenones, and that extra polarity translates into solubility in polar solvents, or enhanced hydrogen bonding in coupling reactions. Structure-performance links emerge most clearly in production settings: the hydroxy group transfers more easily in esterifications and serves as an anchor point in polymer precursor syntheses. Most commercial batches we produce stick closely to the expected melting point and a tightly controlled purity as verified by NMR and HPLC, which means less reprocessing down the line.

    Usage Patterns—From Pilot Scale to the Plant

    Much of our regular demand for 4-Hydroxyheptanophenone comes from specialty intermediates manufacturers, textile auxiliary suppliers, and ag-chem R&D teams. These customers value the compound’s role as a keystone intermediate—one that unlocks a particular pathway to pharma-adjacent molecules or advanced monomers for resins. Our plant often fills orders ranging from kilogram trials in new molecule libraries to multi-ton lots for full-scale syntheses. Custom orders with targeted impurity profiles or solvent systems get frequent attention. End users often perform carbonyl protection or hydroxy group derivatization steps directly on our material, confident that unexpected reactivity from trace byproducts won’t set back yield, purity, or compliance.

    Contrast with Similar Ketones: Why Choose Our 4-Hydroxyheptanophenone?

    Many researchers come to us after encountering setbacks with regular heptanophenone derivatives or off-the-shelf phenolic ketones. Straight heptanophenone may offer stability but lacks the versatile hydroxy group, which limits further modification. Substituted acetophenones, popular for their aromatic core, fall short in certain solubility and polarity-dependent reactions. 4-Hydroxyheptanophenone sits at a sweet spot: the right balance of reactivity and stability, enough lipophilicity to dissolve in organic systems, but enough hydrogen-bonding punch to play nicely in mixed media.

    Our experience in scaling production has shown that trace impurity patterns decide not just outcome quality, but also user safety and environmental performance. By comparison, poorly executed production methods—whether from uncontrolled batch size scale-up or over-reliance on automated pathways—bring along heavy-metal residues, solvent trails, or unexpected aldehyde side chains. Experienced eyes catch these issues early, in line sample tracking, and frequent calibration of analytical equipment. It’s slow, hands-on work, but it brings our product closer to the technical standards demanded by leading innovators.

    Supply Chain Transparency—Lessons Learned Over Time

    Being the manufacturer means more than running syntheses. Our technical staff tracks every raw material, with documentation covering provenance, batch number, and authentication tests for each starting component. From solvent recovery to byproduct management, small improvements in equipment and workflow have led to a significant reduction in cross-batch contamination—a lesson taught by a complex trace residue challenge in our own experience. Close relationships with local suppliers and logistics teams provide the feedback loop needed to stop issues before they scale. Down-to-earth interaction with downstream users closes each production cycle with actionable feedback—leading to a product that reflects not just customers’ paperwork, but their hands-on, day-to-day needs.

    Regulatory Perspective—What End Users Should Know

    Compliance drives every batch—from REACH registration to local workplace safety records. Regulatory requirements regularly change, and as the producer, our teams attend relevant seminars and stay current on global trends. Any raw material flagged as a CMR (carcinogenic, mutagenic, or toxic for reproduction) receives extra scrutiny. Our 4-Hydroxyheptanophenone undergoes regular analytical requalification, with test records accessible to clients on request. Rather than treating compliance as an afterthought or a paperwork hurdle, it adds insight to process adjustments—from solvent substitution to changes in purification column media.

    Customers developing consumer products with stringent end-use criteria often ask about secondary impurity evaluation, trace solvent studies, and batch certificates. We answer with original test data, open process descriptions, and—if needed—fresh in-house runs tailored for specialized specs. This comes from familiar territory: audits, internal spot checks, and close communication with local regulatory bodies. In response to new European Union and North American chemical reporting requirements, we’ve tuned our QC and data retention protocols ahead of the regulatory curve.

    Trouble-Shooting and Support—Learning from Process Realities

    Through years of production, we’ve seen where things can go off-script. Sometimes a seemingly minor tweak in agitation speed or solvent composition shifts product color. Temperature probe drift will change the crystallization endpoint by degrees that matter downstream. To address such challenges, our technical staff tracks data, pinpoints recurring hiccups, and works side by side with maintenance technicians. These lessons color our approach and drive upgrades—whether that means switching out vessel linings, revalidating a dryer, or retraining a crew based on last quarter’s incident log.

    End users often bring us unusual purity standards or ask for variant formulations for pilot programs. Rather than hold them at arm’s length, we invite clients to walk through our process flow and watch our technicians in action. That openness has helped dial in color grades, reduce odorous residues, and keep product off the quality reject line. Support doesn’t stop at delivery. Ongoing tech support—phone, online, or onsite—addresses functional issues as they emerge. Patterns and feedback from these collaborations guide production tweaks for future lots.

    Packing, Handling, and the Simple Details that Matter

    Packing is more than just a step at the end of the line. Through practice, we’ve learned that packaging style and material affect how 4-Hydroxyheptanophenone arrives and performs. Orders for long-distance shipment receive extra-walled high-density containers, paired with moisture-control liners to minimize hydrolysis risks. This extends shelf life and eliminates post-transport clumping, a frustration for many clients working in less-than-ideal warehouse conditions. For on-demand project runs, we keep smaller packs and coordinated batch labeling on hand to ease tracking and minimize errors for later reference.

    Every order receives thorough record-keeping, from batch number documentation to photographic documentation before and after sealing. In our facilities, batch segregation by color grade and origin time prevents cross-mixing. Inventory rotates on a strict FIFO protocol, so customers receive the freshest possible product. New approaches to real-time inventory monitoring and automatic restock alerts cut down on delays, supporting labs running on tight R&D schedules.

    Environmental Responsibility Based on Factory Reality

    Reduction of waste and emissions ties directly to experience on the production floor. We recycle byproducts whenever possible to reduce overall waste. Continuous improvement is not an abstract slogan—it is an answer to specific spills, odor management issues, and fugitive dust events. Worker feedback leads to real changes, from improved gasket material selection to scrubber upgrades that actually match our emission profiles. Byproduct usage closes the loop, supplying non-pharma markets as feedstock, which reduces ultimate landfill loads. When it comes to wastewater, multiple rounds of filtration and pH adjustment cut off-site waste costs and help meet regulator targets.

    End users increasingly ask about environmental footprint. We don’t offer generic platitudes—instead, we point to real investment in solvent reclamation, reduced VOC release rates, and third-party environmental audits. Practical experience tells us which approaches yield real reductions and which only bump numbers on internal reports. We pursue change rooted in measurable impact and report progress with original data, not back-of-the-envelope estimates.

    Tackling Future Demand for 4-Hydroxyheptanophenone

    Future planning rises from patterns we see in demand spikes, regulatory shifts, and process innovation inside our walls. Conversations with customers in advanced materials, specialty pharmaceuticals, and performance coatings show a steady push for higher purity, increased lot sizes, and custom packaging setups. Our process engineers meet regularly to debate incremental technology upgrades, new reactor installations, or process automation steps based on what directly benefits consistent output and reduces downtime.

    Unexpected surges in demand for 4-Hydroxyheptanophenone follow industry launches, research breakthroughs, or regional regulatory changes. We maintain buffer stocks and flexible production scheduling drawn from experience managing previous upswings in acetophenone class intermediates. Close-knit supplier networks built through long-term relationships support emergency ramps, which has trimmed response time through several seasons of volatility.

    Linking Product Development to Manufacturer Experience

    As a producer, we balance quality, safety, and continual improvement every single day. 4-Hydroxyheptanophenone serves not only as a core building block for our clients’ syntheses but as a case study in the benefits of practical, skilled manufacturing. Real-world processes, tailored response to customer feedback, contamination control, and supply chain transparency all combine to build a compound worth choosing over commodity options. Our hands-on team brings deep knowledge to every batch, letting our work speak through the consistency clients rely on. The difference comes from knowing the compound not just by its code or CAS number, but by actually making it, using it, and talking with the people who depend on it most.