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HS Code |
401627 |
| Name | 4-Hydroxydiphenylamine |
| Cas Number | 92-37-5 |
| Molecular Formula | C12H11NO |
| Molar Mass | 185.22 g/mol |
| Appearance | Gray to brown crystalline powder |
| Melting Point | 159-163°C |
| Solubility In Water | Slightly soluble |
| Density | 1.19 g/cm3 |
| Flash Point | 242.8°C |
| Pka | 9.38 |
| Synonyms | N-Phenyl-4-aminophenol |
| Ec Number | 202-151-9 |
| Pubchem Cid | 7148 |
As an accredited 4-Hydroxydiphenylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 4-Hydroxydiphenylamine is packaged in a 100-gram amber glass bottle, sealed with a screw cap and clear hazard labeling. |
| Shipping | 4-Hydroxydiphenylamine is shipped in tightly sealed containers to prevent moisture and contamination, complying with relevant transport regulations. It should be kept away from incompatible substances, direct sunlight, and sources of ignition. Proper labeling and documentation are required, and protective packaging ensures safety during transit. Handle with care during loading and unloading. |
| Storage | 4-Hydroxydiphenylamine should be stored in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizers. Keep the container tightly closed and protected from light and moisture. Use proper chemical storage protocols, including labeling and secondary containment, to prevent leaks and spills. Store away from food and drink. |
Applications of 4-Hydroxydiphenylamine in Industrial Manufacturing4-Hydroxydiphenylamine is a specialty aromatic amine essential in high-performance antioxidant systems, polymer stabilization, rubber additives, lubricant formulations, and advanced pigment synthesis for industrial markets. As a manufacturer, we supply this raw material with full technical traceability for critical downstream sectors requiring controlled reactivity and specific end-use durability. 1. Antioxidant Systems for Rubber ProcessingRubber manufacturers include this raw material in rubber compounding for both natural and synthetic elastomers to inhibit oxidative and thermal degradation during polymerization, extrusion, and vulcanization. Its role preserves mechanical properties and aging resistance, particularly in high-stress applications such as automotive and industrial heavy-duty tires, conveyor belts, and sealants. The compound’s solubility and secondary amine structure enable its integration without affecting curing kinetics. Industry compliance standards
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2. Stabilizer in Lubricant Additive ManufactureLube oil additive blenders leverage the chemical’s antioxidative capacity for crankcase and hydraulic oils, especially where extended drain intervals and high operational temperatures create free radical formation risks. It acts as a sacrificial scavenger, maintaining viscosity and TBN levels, and is introduced during batch blending prior to quality control testing. The chemical remains effective without impacting base oil solubility or metallic detergent reactions, ensuring system compatibility in advanced engine protection fluids. Industry compliance standards
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3. Intermediate for High-Performance Pigment SynthesisFine chemical producers apply 4-hydroxydiphenylamine as a key intermediate during the synthesis of specialty azo and anthraquinone pigments. Its aromatic structure enables reactivity with diazonium salts, supporting chromophore extension and providing thermal stability for high-temperature plastic and paint applications. Synthetically, it enters controlled coupling reactions in aqueous or organic media, ensuring purity and tinctorial strength in coloring agents used in advanced plastics and coatings. Industry compliance standards
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4. Polymer Stabilizer in Engineering PlasticsProducers of engineering polymers introduce this compound during melt processing of polyamides, polyesters, and polycarbonate blends to improve long-term oxidative and thermal stability. Particularly in fiber and molded part production, the additive delays yellowing and embrittlement under environmental stress, extending product life in automotive interiors, construction, and electronic component housings. The stabilizer does not interfere with photo-stabilizer or flame retardant packages. Industry compliance standards
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Some chemicals seem small or simple until you put them to work inside rubber factories or research labs where demands are real. 4-Hydroxydiphenylamine is one of those unsung materials that pulls more of its weight than its mouthful of a name would clue you in on. Manufacturing it, we spend the better part of two decades listening to end-users and monitoring process quirks so we can offer a product that helps others solve daily challenges. The model we ship today comes from tuning each batch with a close eye on purity, color, and stability—those are the qualities real customers argue and sweat over, not just lines on a spec sheet. Our regular product features a purity typically >99%, which skips hours on cleanup and lets you trust each lot from the first shipment to the last drum in the stack.
If you’ve worked with antioxidants for rubbers or specialty intermediates in dyes, you know not every molecule with a similar skeleton acts the same under stress or processing conditions. 4-Hydroxydiphenylamine packs a punch as both an antioxidant for rubbers and as an intermediate for color-forming reactions where stability under heat or mixing matters. The hydroxyl group gives it a reactive edge, improving its interaction with oxidizing agents. That boosts the lifespan of your finished products—rubber sheets love it, and so do folks compounding technical-grade elastomers where failure is expensive. Safety margins depend on that toughness, and users come to the manufacturer after losing too much money to failing performance additives.
Unlike simple diphenylamines or even 4-nitrodiphenylamine, this material tolerates tough process steps. Its molecular structure reduces side reactions during compounding, which cuts headaches with odor, color contamination, or unwanted softening. We’ve run plenty of side-by-side tests with basic diphenylamines in tire and shoe rubber; longevity on simulated road testing shows up to 20% extended oxidation resistance, and that’s something you notice after months, not just in the lab. Customers tell us melting points above 150°C and consistent, almost off-white color help when blending into sensitive polymer systems. That stability also lets the downstream user delay adding stabilizer until later in their process, cutting losses of expensive actives at high blend temperatures.
You get to know the limits of your material by watching reactors, not just reading about them. 4-Hydroxydiphenylamine’s manufacture demands strict control of reaction conditions and purification, or you’ll pick up color bodies and trace byproducts that make users angry. We adjust parameters in real time based on analytical feedback—gas chromatography, melting point, ash, and spectral analysis. The batches we produce undergo post-synthetic purification for low iron and minimal organic contamination. Over many years, only practice taught us how minor tweaks in solvent systems and reaction agitation prevent localized overheating and decomposition. These subtleties rarely appear in textbooks because they grow out of everyday troubleshooting and missed targets. You keep batch-to-batch consistency by never relaxing these standards, even when raw materials vary by source or season. As a result, our specifications on heavy metal content and overall organics meet demands for both general compounding and specialty coloring.
For us, it’s also about minimizing risk for the end users. Purity and color stability are discussed as if they’re maintenance issues for plant managers. Chemical companies need a supplier whose raw material properties stay tight, or downstream processes stall—EPA audits, lost production hours, unsaleable lots hanging out in the warehouse. Stories about color drift or batch failures often circle back not to end-process mistakes, but to small lapses during intermediate purification or drying. We run additional drying and stabilization cycles under vacuum and inert gas, and every lot gets archived for traceability as a reference in case future complaints come up months or years down the line.
The straightforward application is antioxidant use in synthetic and natural rubbers—particularly in tires, technical goods, belts, and seals where ozone and heat start gnawing away at mechanical strength. A few grams mixed at the right moment greatly slows surface hardening and embrittlement. Real-life product recalls in automotive or heavy-equipment sectors have proved that a small improvement in antioxidant quality pays for itself many times over. Customers who switch to high-purity 4-Hydroxydiphenylamine often cut sample failures by half during QC checks. This underpins why risk-averse clients—think aerospace seals or bridge bearings—tend to specify the product by brand or documented batch records, not just the chemistry textbook name.
A less-known but growing market is specialty pigment and dye synthesis. The presence of the hydroxy group at the para position changes the way the material behaves during diazotization and coupling reactions, so end colors are brighter and more light-fast than with unsubstituted analogs. Textile colorists or ink manufacturers see improved yield and chroma stability in certain formulations. We work with labs pushing boundaries on color matching, and tighter raw material specification on 4-Hydroxydiphenylamine makes their process repeatable—less overshoot on target shades, fewer off-tints that land in the reject bin. Investing time in controlled crystallization and careful filtration, we reduce the fine particulate load that could otherwise alter shade or reduce shelf life. Repeat customers send feedback and failed trial samples that, in turn, refine our purification methods and drying cycles.
Comparisons often come up between 4-Hydroxydiphenylamine and other phenylamines like p-aminodiphenylamine or even straight diphenylamine. Each looks similar on a chart, but plant performance weeds out the differences. 4-Hydroxydiphenylamine’s combination of an amine and a para-hydroxyl group increases reactivity, which helps antioxidant function and intermediate synthesis. In practice, this means better outcomes in materials subjected to high-heat vulcanization or repeated sterilization. Unlike some para-substituted aminodiphenyls, this molecule resists deep oxidation, yielding softer changes in color and less unwanted interaction with fillers. Processors working near the limits of their formulations rely on this predictability and lower odor profile. Our rigorous approach to purity (with total impurities below 0.3%) means users rarely need to buffer blends against competitive side reactions, something less well-defined analogs might force by default.
Even suppliers for laboratory research benefit. Many high-performance labs require a sharper melting range (above 155°C, typically tightly defined to under 2°C width) and nearly invisible color, since even faint yellowing can throw off a precise kinetic study or colorimetric assay. By focusing on these aspects, we’ve carved out a spot as a high-end supplier, rather than mass-market vendor only chasing volumes. For companies building new composite materials or high-value specialty elastomers, it often comes down to whatever helps reduce variables in scale-up—from benchtop to large kettle. Our lot-release documentation provides transparency on residual solvent content, water, and iron—all potential fatal flaws in sensitive downstream chemistry or polymerization.
Over the years, our team has seen industry shift from volume-at-all-costs to cleaner, safer, and less wasteful operation. With 4-Hydroxydiphenylamine, we took early steps to close reaction loops, recover solvents, and reduce total organic emissions. Plant engineers invested in better distillation columns, and maintenance protocol now catches cross-contamination before it reaches the drying drum. Instead of sending every off-spec kilogram for burning, we unwind each failure and recover usable fractions, feeding them back into the process or converting to value-added materials. Analyst teams now run quarterly reviews on yield-to-waste ratios and environmental loading, not just production throughput.
We also invested hard in operator training around powder transfer and solvent handling. Simple habits—sealed weighing rooms, more efficient vacuum transfer—now cut dust and improve recovery rates, limiting where dust escapes onto plant floors or into scrap bins. Open communication accounts for most improvements. Workers notice small upsets sooner than any computer could. Over time, those little process tweaks add up. We advocate for more engagement between floor staff, maintenance, and chemists, as problems fixed at the source rarely escalate to recalls or audits. This tight operational loop helps downstream users sleep at night, confident their supplier is practicing attention to detail and environmental care, not just printing certificates for the file cabinet.
There’s a constant pressure to shave pennies by switching to “equivalent” suppliers or relaxing specs for materials like 4-Hydroxydiphenylamine. Over the last ten years, companies burned by off-spec antioxidants or untraceable batches call us after experiencing higher product failures, color mismatch, odd odors, or performance slippage in service parts. Those failures rarely balance out with the cost savings on paper. We’ve been pulled in on consulting after batch-failed seals, faded athletic outsoles, and even large-run tire recalls. Each time, root cause investigations link back to an overloaded impurity profile, inconsistent melting, or missed QC signals—the kind of issues you prevent with tighter controls but pay for up front. In a world of increasingly complex supply chains, keeping direct lines of communication with chemical engineers, plant managers, and formulation chemists builds trust. If something seems off—even a subtle difference in batch color—customers reach out and get a real answer or a replacement at short notice.
Global competition over the last decade makes holding prices stable a major headache. Raw material volatility and shipping uncertainty emphasize how knowledge of your own process saves time and cost. We have built redundancy into some precursor production and built partnerships with neighboring plants to ensure continuity. Customers downstream see little of this—their only concern is whether the latest drum or sack performs the same as the last. That’s the only correct standard. Problems with unstable grades or missed delivery timelines create headaches all the way from production to after-sales. Shipping quality-tested and moisture-stabilized materials in tamper-evident packaging might seem like a small effort, but stories abound of material stored too long or repacked in moist air, showing up clumpy or with shifted melting points. Simple investment in proper bag liners and reactive-gas purging solves dozens of those headaches before a single complaint form ever appears.
Some of the best insights come not from your own R&D lab, but from listening to end-users fighting live plant problems. We maintain direct partnerships with rubber product testing centers and pigment developers who stress-test antioxidants across product lines, compounding conditions, and extreme service. Field feedback informs our improvements in both upstream chemistry and post-synthesis treatment—cleaner, less dust-prone grades for automation, or tighter grind for easier dispersion into latex. Our technical team tests new batches in simulated wear studies, following real exposure to light, ozone, and repeated thermal cycling, to watch for changes that don’t appear in jars on the shelf.
Committing to regular audit of equipment cleanliness and environmental impact sharpens every employee’s awareness. Annual investments in inline monitoring—spectroscopy, chromatography, moisture balance—cut dispersity and help us catch trends before a customer does. Collaboration with customers acts as a force multiplier; side-by-side plant visits with QC managers and feedback sessions yield incremental, ongoing improvements. If a user wants special particle size, we work out logistical controls: dedicated mill time, extra sieving, and humidity tracking all the way through shipping. The point is to make production operate with fewer surprises, not just to tick off compliance boxes. Flexible lot sizing, adjusted to customer needs, helps minimize warehouse time and wasted material, especially in volatile or just-in-time manufacturing cycles.
4-Hydroxydiphenylamine serves not just rubber plant managers but also technical teams in coatings, adhesives, agricultural compounds, and specialized dye areas where performance depends on small details. As new polymers and advanced materials come to market, formulators continue to push for tighter ingredient specs, improved dispersibility, and cleaner color for high-appearance and technical applications. Our long experience in adapting material to end-user constraints—whether pigment crystal growth, rubber blend compatibility, or downstream chemical stability—lets our chemists provide more informed process guidance. We regularly supply samples for pilot trials at diverse scales, supporting customers as they ramp from benchtop to intermediate production. For demanding R&D teams, the conversation rarely ends after the first delivery; feedback on interactions, shelf life, and storage behavior gets fed back into ongoing process optimization.
Our reach with 4-Hydroxydiphenylamine isn’t limited to domestic use. Export partners dealing with challenging shipping climates or customs requirements appreciate having documented quality and transparency. Shipments are made only after third-party labs confirm alignment with local or international standards, and after technical staff engage directly if a concern pops up in overseas labs. This accountability, built over years of repeated performance and honest problem-solving, distinguishes the manufacturer who shapes their product with pride from a commodity shipper chasing the next convenience market.
Every batch of 4-Hydroxydiphenylamine carries the lessons of hundreds of small failures, quick saves, and gradual improvements over the years. Unlike traders or repackagers, we live with the real-world feedback from each shipment and each end-use complaint or compliment. The customer relationship lives in every adjustment of our process and each line of quality documentation. Antioxidants, dye precursors, and specialty intermediates may look common from a distance, but day-to-day realities in manufacturing, raw materials, and end-user safety can draw a big line between “good enough” and trusted source. In our experience, iterating with feedback and building production discipline produces not only steadier performance and reliability, but also better outcomes for everyone from compounders and colorists to procurement, logistics, and long-run maintenance teams. Our persistent attention to each step from raw precursor through to post-purchase support defines what it means to actually manufacture a reliable chemical and support the industries that rely on it every day.