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4-Hexyl-1,3-Benzenediol

    • Product Name 4-Hexyl-1,3-Benzenediol
    • Alias A-003
    • Einecs 401-720-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    266775

    Chemical Name 4-Hexyl-1,3-Benzenediol
    Molecular Formula C12H18O2
    Molecular Weight 194.27 g/mol
    Cas Number 2081-12-1
    Appearance White to off-white solid
    Melting Point 76-80°C
    Boiling Point 336.1°C at 760 mmHg
    Solubility Slightly soluble in water; soluble in organic solvents
    Purity Typically ≥98%
    Storage Conditions Store in a cool, dry place, tightly closed

    As an accredited 4-Hexyl-1,3-Benzenediol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g amber glass bottle with screw cap, featuring hazard labels and product details: "4-Hexyl-1,3-Benzenediol, 250g, for laboratory use only."
    Shipping 4-Hexyl-1,3-Benzenediol is shipped in tightly sealed containers to prevent contamination and moisture exposure. It should be transported at ambient temperature, in compliance with chemical handling regulations. Proper labeling and documentation are required. Ensure containers remain upright and secure during shipping. Avoid sources of ignition, as the material may be combustible.
    Storage 4-Hexyl-1,3-benzenediol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from direct sunlight and incompatible substances such as strong oxidizers. Avoid excessive heat and moisture. The storage area should be clearly labeled and restricted to trained personnel. Follow all relevant safety data guidelines and regulatory requirements for safe chemical storage.
    Application of 4-Hexyl-1,3-Benzenediol

    Applications of 4-Hexyl-1,3-Benzenediol in Industrial Manufacturing

    4-Hexyl-1,3-Benzenediol serves as a specialty intermediate with key performance properties for several advanced industrial sectors. We manufacture this material under tightly controlled conditions for downstream integration into precision formulations. Below, we detail its application in specific, high-value fields, reflecting real market adoption and compliance requirements.

    1. Antimicrobial Additives for High-Performance Polymer Compounds

    Leading polymer compounders use 4-Hexyl-1,3-Benzenediol as a biostatic and biocidal additive in the formulation of antimicrobial plastics. Its molecular structure disrupts bacterial membranes, delivering lasting activity in molded and extruded resins for touch surfaces and medical housings. Production teams incorporate it during resin compounding to achieve uniformity and leach stability, critical for post-molding functional verification and quality assurance in regulated items.

    Industry compliance standards

    • ISO 22196: Measurement of antibacterial activity on plastics and non-porous surfaces
    • REACH (EC 1907/2006) substance registration
    • RoHS 2011/65/EU for electrical and electronic equipment safety
    • FDA 21 CFR 177.1010: Polymers for food-contact surfaces (for appropriate grades only)

    Typical usage ratio

    • 0.3%–1.2% by weight in masterbatch or directly in melt blending, depending on targeted microbial resistance level and resin matrix compatibility

    Downstream process integration

    • Direct incorporation during extrusion or injection compounding
    • Ensuring homogenous dispersion via twin-screw extruder for pelletized masterbatch
    • Heat profile management (>200°C) to avoid decomposition
    • Post-blend stability QC in finished parts

    Final product types

    • Medical device housings
    • Consumer electronics casings
    • Public transportation handrails
    • Food processing conveyor surfaces

    2. Preservative for Industrial Adhesive Formulations

    Formulators use this material to inhibit bacterial and fungal degradation in waterborne adhesive systems destined for high-humidity or high-volume packaging lines. Its high solubility and low volatility support stable dispersion and extended pot life, preventing spoilage during bulk storage. Production focuses on batch-level integration and downstream compatibility with rheology modifiers, plasticizers, and resin emulsions to maintain performance during shelf life.

    Industry compliance standards

    • Biocidal Products Regulation (EU) 528/2012
    • EPA 40 CFR Part 158 for antimicrobial pesticide registration
    • ISO 846: Determination of behavior of plastics against fungi and bacteria
    • DIN EN 15457 for adhesives in construction applications

    Typical usage ratio

    • 0.05%–0.8% by total formulation weight, adjusted based on emulsion type, expected pH, and geographic microbial exposure risks

    Downstream process integration

    • In-tank blending post-resin synthesis to ensure compatibility
    • Continuous mixing during scale-up to avoid hot spots and local overdose
    • QC by plate count microbial challenge for every production batch
    • Verification of physical properties post-addition

    Final product types

    • Construction adhesives (tiles, panels)
    • Pressure-sensitive label adhesives
    • Packaging sealants for food and beverage
    • Hot-melt adhesives for high-speed assembly

    3. Biocide for Industrial Coatings and Paint Systems

    Specialty coating producers incorporate 4-Hexyl-1,3-Benzenediol to prevent microbial colonization, discoloration, and odor in interior and exterior paint systems, especially for healthcare and sanitation sectors. The compound withstands demanding curing profiles and interacts compatibly with acrylic, polyurethane, and epoxy resin networks. Labs monitor wet-state and dry-film performance to meet both application durability and in-service hygiene requirements.

    Industry compliance standards

    • EN 15457: Fungal resistance of coatings
    • ASTM D3273: Mold resistance of interior paints
    • EPA TSCA Inventory listing for antimicrobial agents
    • ISO 11998: Wet-scrub resistance for coating durability

    Typical usage ratio

    • 0.1%–0.5% per wet weight, tuned to resin chemistry, film thickness, and local biohazard assessment

    Downstream process integration

    • Post-emulsification addition under high-shear mixing
    • Monitoring with accelerated shelf life testing at defined RH and temperature
    • Verification in finished coating panels for microbial challenge and gloss retention
    • Compatibility checks with pigment and thixotrope packages

    Final product types

    • Hospital wall paints
    • Food factory floor coatings
    • Anti-mold architectural finishes
    • Laboratory cleanroom paints

    4. Intermediate for Cosmetic Preservative Synthesis

    Personal care chemical manufacturers select 4-Hexyl-1,3-Benzenediol as a strategic intermediate for producing specialized cosmetic preservative actives. Through controlled etherification and partial hydrogenation, plants generate downstream molecules delivering broad-spectrum antimicrobial protection for sensitive creams and aqueous lotions. Strict raw material handling and traceability protocols ensure compliance with international cosmetic ingredient listings and batch reproducibility.

    Industry compliance standards

    • EU Regulation (EC) No. 1223/2009: Cosmetic safety requirements
    • INCI registration and listed preservative reviews
    • ISO 22716: GMP for cosmetics manufacturing
    • Cosmetic Ingredient Review (USA) assessment status

    Typical usage ratio

    • Varies by target molecule pathway. For direct inclusion in unmodified form, regulatory limits usually require <0.3% in finished product. For chemical intermediate applications, input determined by process stoichiometry.

    Downstream process integration

    • Batch synthesis via catalytic etherification
    • Continuous-flow hydrogenation for active derivative formation
    • In-process QC for identity, purity, and microbial challenge
    • Isolated intermediate shipment for further compounding

    Final product types

    • Cosmetic emulsions (face creams, body lotions)
    • Rinse-off cleansers
    • Preservative booster blends
    • Personal care wet wipes

    5. Antimicrobial Component for Water Treatment Formulations

    Water treatment chemical producers use 4-Hexyl-1,3-Benzenediol for formulating biocidal concentrates aimed at controlling algae, bacteria, and fouling organisms in closed-circuit systems and process water loops. Its industrial-grade purity allows stable blending with other biocides and corrosion inhibitors. Operations focus on tank compatibility, metering accuracy, and ongoing field monitoring to maintain compliance with environmental discharge limits and system performance.

    Industry compliance standards

    • ANSI/AWWA B451: Disinfectants for industrial water
    • EPA FIFRA registration for antimicrobial active substances
    • ISO 9001:2015 for water treatment chemical manufacturing
    • REACH authorization for product blends within EEA markets

    Typical usage ratio

    • Formulated at 50–1,000 ppm active content in system water, adjusted according to system volume, bio-load, and required residual levels

    Downstream process integration

    • Added during preparation of concentrate blends in dosing tanks
    • Automated feeding into system makeup water in industrial loops
    • Periodic monitoring for degradation and adjusting dosing intervals
    • Compatibility checks with corrosion control additives

    Final product types

    • Cooling tower biocidal concentrates
    • Process water cleaning solutions
    • Closed-system biocide packages
    • Poultry and livestock water sanitation chemicals
    Free Quote

    Competitive 4-Hexyl-1,3-Benzenediol prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    4-Hexyl-1,3-Benzenediol: An Insider's View from Manufacturing

    Making Sense of 4-Hexyl-1,3-Benzenediol

    Those who spend their days next to reactors and synthesis lines get to know 4-Hexyl-1,3-Benzenediol on a level that goes deeper than the chemical structure. Each batch comes with its own challenges, subtle adjustments, and quality checks. It’s not just about producing another aromatic diol. For us, the story always starts with the need for reliability and clear performance results where this molecule gets put to use.

    Model and Specifications Built From Real Demands

    We manufacture 4-Hexyl-1,3-Benzenediol under the CAS number 607-57-8. The chemical formula, C12H18O2, only hints at the possibilities inside each drum. Our standard purity consistently exceeds 99.0% by GC analysis, and water content stays tightly controlled under 0.3% as measured by Karl Fischer. Appearance always gets double-checked before shipment; you’ll see an off-white crystalline powder with a faint floral note. What laboratory books usually miss is that off-spec batches show up less from raw material hiccups and more from humidity and packaging errors. That’s why controlling every step, from solvent selection to dry room storage, matters here every single day.

    Inside the Manufacturing Process: Challenges and Solutions

    Speeding molecules through a reaction vessel is only the beginning. The main synthetic route involves Friedel-Crafts alkylation on resorcinol, using a controlled injection of n-hexyl halide. Old hands know that monitoring the exotherm is crucial. Letting temperatures spike, even by a few degrees, triggers a runaway reaction and wastes good reagents. Selecting the right acid catalyst cuts down on tri-alkylated by-products. We’ve experimented with tweak after tweak—moving from aluminum chloride to more manageable Lewis acids, adjusting agitation speeds, keeping a close eye on time-to-completion through in-line analytics. Our main focus lies in balancing scale with repeatability.

    Each time a batch finishes, our QC team and R&D people argue over IR spectra, HPLC peaks, and the hint of color forming near the melting point. The importance of good solvent recovery and scrupulous equipment cleaning stands out; contamination or solvent residues not only mess with purity but also set off unexpected reactions during storage. Our process doesn’t leave much to chance. The extra time spent post-run in vacuum drying or recrystallizing leads to better shelf life for you, fewer recalls for us.

    Applications Growing with Expectations

    Most customers approach us searching for 4-Hexyl-1,3-Benzenediol as an intermediate and functional additive. In actual industrial settings, it gets added to formulations for long-chain aromatic derivatives, not just in flavor and fragrance development but also in specialty coatings, polymer additives, and, more recently, as a building block in fine electronics chemicals. Where users want robust antioxidant activity or consistent modification of film properties, this benzenediol stands out.

    We’ve partnered directly with R&D labs looking to push boundaries, especially among clients who expect tolerances in the low ppm for impurities. They need to match international regulatory demands, particularly in cosmetics and functional coatings. The conversations go far beyond a technical data sheet; those who actually use our product often want to know about extractables, the effect of packaging material, and trends with photo- or thermo-stability. Answering those questions takes both control over production and direct experience on the shop floor.

    Real-World Differences from Other Aromatic Diols

    Working hands-on with 4-Hexyl-1,3-Benzenediol proves right away it’s not interchangeable with other aromatic diols like simple resorcinol or 4-tert-butylcatechol. The long hexyl chain gives it an edge in compatibility with both polar and nonpolar solvents. You notice improved solubility in organic systems, a useful property when blending with complex resins or advanced plastics. That chain also introduces controlled hydrophobicity, so unlike shorter-chain diols, it shows a defined influence on plasticizer blends and modified surface properties.

    From our own observations, it takes less effort to dissolve in less common carriers, which opens up technologies for water-repellent treatments and specialty lubricants. Those aiming for anti-microbial or preservative actions welcome the dial-in control on leaching and volatility. Resorcinol derivatives without that long alkyl tail can’t match durability under harsh processing. Doing side-by-side tests in our own labs, we’ve measured greater oxidative stability and a marked difference in molecular orientation when mixing into synthetic film matrices.

    Why End-Use Performance Depends on Reliable Manufacturing

    For the end-use properties to shine, all the upstream work in process chemistry and quality management counts. We understand most customers don’t just want high purity—they want lot-to-lot reproducibility. Our traceability program records each parameter shift, from reaction temperature logbooks to pH at every wash cycle. All of this effort limits batch variability and ensures function, whether for further derivatization or direct incorporation in sensitive applications. Big project launches in advanced materials rise and fall on the back of raw material reliability.

    Consistency means more than matching certificate numbers. We monitor not just listed impurities but also broad-spectrum by-products, especially cresolic and overalkylated analogs that can frustrate downstream formulation. Since most of the applications for 4-Hexyl-1,3-Benzenediol go toward value-added, high-performance markets, our technical and QC teams routinely engage in advanced analytics to flag trace contaminants that could trigger regulatory issues abroad. End-users working in consumer products, especially those formulated in Japan, the EU, or North America, demand our attention to detail when it comes to migration potential and residual solvents.

    Supporting Innovation Through Technical Partnership

    Product lines have evolved as science pushes the boundaries of function. Companies approach us with problems, not just purchase orders. A coatings client came in with conductivity issues in an anti-static layer—they suspected trace ionic contamination in raw ingredients. We put together a special batch monitored for ionic residue throughout every purification stage. The issue resolved; subsequent trials ran clean, and their production line uptimes rose. Another project focused on biodegradable plastics had issues with chain scission under ultraviolet exposure. Our R&D team collaborated on oxidative stress testing, tweaking our hexyl-benzylic synthesis to minimize side products. We fed the results back to their lab, and soon their material qualified for a higher shelf-life rating.

    Our facility isn’t static. We push continuous improvement initiatives based on real-world feedback. Process engineers reexamine catalyst profiles following stumbling blocks in scale-up batches. The plant floor staff keep data on seasonal solvent losses, correlating it to subtle shifts in drying time or humidity. Small changes, like updated nitrogen blanketing protocols and improved packaging inner linings, can add months to shelf life on customer shelves. We also keep a close relationship with logistics teams, recognizing how climate and customs delays change actual user experience.

    Trust Built from Transparent Practices

    End-users often want more than just compliance—actual transparency about how the material arrives at its stated specs. We believe in sharing not just batch analytics but also stories from the shop floor. Changes in raw material supplier or tweaks in the drying temperature get logged and relayed on request. Technical teams occasionally invite customer audits, opening the door to continuous learning both ways. Having that open channel saves time and energy for everyone. When a new application comes in, such as for biodegradable surfactant blends or performance sealants, early dialogue on process capabilities speeds up scale-up. Our lab teams stand ready to modify process or hold material for parallel R&D lots, if a project needs it.

    We also bring experience navigating changing regulatory environments. New policies around allowable extractables, restrictions on certain aromatic analogs, and evolving norms on residual solvents mean ongoing investment in analytics and documentation. Certification requirements keep raising the bar, especially for high-value markets in personal care or packaging. The only defensible answer lies in documenting every step, practicing batch-to-batch repeatability, and staying ahead on both the science and paperwork.

    Working Toward Next-Generation Applications

    Beyond static uses, we see research directions ranging from controlled-release agents right up to molecular electronics. Our investment in pilot-scale synthesis modules means we can adjust process variables or test new synthetic routes if a customer needs something outside standard specification. We’ve scaled batches in unusual solvents, changed particle size profiles by adapting crystallization regimes, and worked directly with application chemists to co-develop test runs. Internal benchmarks use not only regulatory-driven purity analyses but also functionality outcomes—real compatibility, stability, and downstream behavior, tracked side-by-side in formulations mimicking end-use.

    As newer end-use requirements grow, so does the expectation for both analytical and logistical support. The lab team can provide fresh stability studies if a customer looks toward longer storage or exposure to particularly harsh process conditions. Packaging technology adapts, moving from fiber drums to high-barrier multilayers depending on moisture or oxygen protection needed in shipment. Model numbers or specifications become less abstract, more attached to what each industry faces in its development cycle. We keep our technical documentation evolving and don’t treat compliance as just a checkbox.

    Continuous Feedback from the Manufacturing Frontline

    Years spent running both small and large lots bring a certain humility to claims about ease or uniformity. Scale-up rarely follows a straight line. Differences open up as soon as you ramp volume and switch from glassware to steel. Agitation speeds that looked safe for a 10-liter flask can cause mixing dead zones in a 2,000-liter reactor, changing purity and color. Chemistry may be global, but hands-on know-how on the actual floor bridges theory and reliable output.

    Experienced operators maintain written feedback logs, charting unexpected shifts in viscosity or color retention. That sort of hands-on vigilance flags potential issues before they reach a drum or bag ready for shipment. Sometimes it’s a cleaning solvent that leaves a spectroscopic fingerprint—the kind of detail you wouldn’t see above detection limits unless you routinely review both outgoing and archived data. Root cause analysis works best as a team effort; an unexpected analytical blip sends our operators and lab technicians working side by side to replicate the observation, test process samples, and close the loop.

    Customers Return to Consistency, Not Just Price

    The difference between average and trusted 4-Hexyl-1,3-Benzenediol isn’t just in a line item cost or basic purity reading. Those we serve feedback on what delivers: lower downtime on lines, predictable reactivity in batch runs, and the absence of headaches when switching suppliers. Building actual partnerships with users centers on transparency, real fixes to problems, and continuous upgrades in process and documentation. We don’t chase trends to undercut price; our focus lands on what creates value for people who use the material in production, research, or product development.

    New users often approach us after a frustration with another supply—maybe a blocked filter or an unexpected odor at scale. By keeping tight control over variables, agreeing to trial projects, or sharing detailed stability files, we’ve turned those initial doubts into longstanding cooperation. Our approach boils down to making sure every batch matches what’s expected, both on paper and out in the plant.

    Final Thoughts on Manufacturing for Performance

    Producing 4-Hexyl-1,3-Benzenediol is more than chemistry for us. It embodies a blend of tradition, adaptation, and plain diligence through every step. We’ve tuned each phase, from raw material qualification to final shipment, to fit with what end-users genuinely need. Documentation, logistics, real experience, and two-way technical exchange make the difference. Our reputation stands on batches that perform in practice, not just pass tests on a certificate. We look forward to building the same standard and reliability into every lot, welcoming the next challenges from innovators who turn this molecule into applications across industries.