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4-Ethylbenzoic Acid

    • Product Name 4-Ethylbenzoic Acid
    • Alias p-Ethylbenzoic acid
    • Einecs 212-677-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    116102

    Chemical Name 4-Ethylbenzoic Acid
    Cas Number 619-64-7
    Molecular Formula C9H10O2
    Molecular Weight 150.17 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 173-176 °C
    Boiling Point 292 °C (estimated)
    Density 1.14 g/cm3 (at 25°C, estimated)
    Solubility In Water Slightly soluble
    Pka 4.29
    Smiles CCc1ccc(cc1)C(=O)O
    Inchi InChI=1S/C9H10O2/c1-2-7-3-5-8(6-4-7)9(10)11/h3-6H,2H2,1H3,(H,10,11)

    As an accredited 4-Ethylbenzoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 4-Ethylbenzoic Acid, packaged in a sealed amber glass bottle with printed label detailing chemical name, formula, and safety information.
    Shipping 4-Ethylbenzoic Acid is securely packaged in sealed, chemically-resistant containers to prevent contamination and ensure safe transport. It is shipped according to standard chemical shipping regulations, typically via ground or air freight, with clear hazard labeling. Appropriate documentation and safety data sheets accompany each shipment for regulatory compliance and safe handling.
    Storage 4-Ethylbenzoic acid should be stored in a tightly sealed container in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizing agents. Protect from moisture and direct sunlight. Ensure proper labeling and keep away from sources of ignition. Store at room temperature, and keep out of reach of unauthorized personnel or children.
    Application of 4-Ethylbenzoic Acid

    Applications of 4-Ethylbenzoic Acid in Industrial Manufacturing

    4-Ethylbenzoic Acid serves as a functional intermediate in multiple chemical manufacturing sectors, with distinct downstream uses driven by precise compliance standards and process requirements. Our factory ensures traceable quality and consistency tailored for each application stream detailed below.

    1. Polymer Synthesis: Specialty Polyesters and Polyamides

    Producers in the advanced polymer sector incorporate this acid as a tailored monomer for niche polyesters and polyamides, where aromatic character and ethyl substitution modify thermal and mechanical properties for targeted engineering plastics. Customers value its utility in copolymerization with terephthalic acid or other aromatic acids to influence polymer crystallinity, chemical resistance, and melt flow parameters.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • REACH Regulation (EC) No 1907/2006 compliance for subcomponents
    • RoHS Directive 2011/65/EU for electrical polymer grades
    • ASTM D7641 for aromatic polyester raw material purity

    Typical usage ratio

    • 1–5 mol% of total diacid content in copolymer formulations
    • Exact percentage tunes glass transition and melting points; final ratio determined by downstream mechanical and thermal targets

    Downstream process integration

    • Charged during esterification or amidation alongside bulk monomers
    • Pre-dried and introduced to reactor under nitrogen to prevent oxidation
    • Fully integrated prior to high-temperature polycondensation

    Final product types

    • High-heat automotive parts (specialty polycarbonate blends)
    • Polyester films and fibers with enhanced chemical stability
    • Injection-molded electrical housings
    • Engineering nylon copolymers

    2. Performance Coatings: Alkyd and Polyester Resin Modification

    Specialists in high-performance coatings and industrial paints use this acid to modify alkyd and saturated polyester resins, providing improved solvent resistance and hardness in cured films. Selection of this acid helps formulators adjust crosslink density and film flexibility, enabling compliance with demanding automotive and general industrial coating standards.

    Industry compliance standards

    • EN ISO 12944-6 Paints and varnishes—Corrosion protection
    • GHS Hazard Communication and Safety Data Sheet (SDS) requirements
    • TSCA Inventory listing in the United States
    • Directive 2004/42/EC for VOC reduction in paints

    Typical usage ratio

    • 3–10 wt% of dicarboxylic acid fraction in alkyd resin batch
    • Adjusted according to targeted flexibility, hardness, and weathering characteristics

    Downstream process integration

    • Incorporated during acidolysis step with polyols and other aromatic acids
    • Continuous monitoring of acid value and molecular weight throughout polycondensation
    • Blended to final resin specification before let-down with solvents and driers

    Final product types

    • Industrial metal coatings for rail, bridge, and heavy equipment
    • Protective automotive primers
    • Decorative architectural paints
    • High-durability enamels

    3. Pharmaceutical Intermediate: Synthesis of Active Pharmaceutical Ingredients (APIs)

    API manufacturers use 4-Ethylbenzoic Acid as a reagent for specific benzoic acid derivatives in custom syntheses. The unique ethyl substitution enables selective functionalization on the aromatic ring, forming structural motifs essential for small-molecule drugs and intermediate compounds. Batch documentation and impurity control are crucial for pharmaceutical regulatory submission.

    Industry compliance standards

    • Good Manufacturing Practice (EU GMP, ICH Q7)
    • United States Pharmacopeia (USP) for defined intermediates
    • 21 CFR Part 211 for finished pharmaceuticals
    • ICH Q3A/B guidelines for impurity profiling

    Typical usage ratio

    • Stoichiometric amounts based on reaction yields (typically 1.0–1.3 equivalents)
    • Adjustments made depending on synthesis efficiency and target purity

    Downstream process integration

    • Dosed by weight as starting material or intermediate in multi-step syntheses
    • Subjected to controlled reaction conditions, including temperature, pH, and solvent optimization
    • Residual acid content and trace impurities monitored to meet specification

    Final product types

    • Non-steroidal anti-inflammatory drug (NSAID) intermediates
    • Anti-hypertensive agent intermediates
    • Specialty contrast agents (raw material for aromatic ring functionalization)
    • API building blocks for custom syntheses

    4. Organic Synthesis: Manufacture of Custom Aromatic Derivatives

    Producers of aromatic intermediates use this acid as a vital building block for syntheses requiring an ethyl-substituted aromatic core. Established reactions include Friedel-Crafts acylation, esterifications, amidations, and functional group conversions for agrochemical, fragrance, and dye markets. Reliable supply and consistent purity support downstream process validation and scale-up under regulated manufacturing conditions.

    Industry compliance standards

    • REACH SVHC screening for all custom synthesis inputs
    • ISO 14001:2015 for environmental management
    • Responsible Care program alignment for process safety
    • Custom specification documentation (COA traceability, batch testing)

    Typical usage ratio

    • Variable, typically 1 equivalent in condensation or substitution reactions
    • Adjusted per process scale and yield optimization studies

    Downstream process integration

    • Added at initial charge with Lewis acid catalysts in acylation or amidation
    • Pre-dissolved for continuous feeding in flow chemistry arrangements
    • Processed through crystallization and filtration prior to downstream reactions

    Final product types

    • Custom fragrance and flavor intermediates
    • Semi-finished dye coupling agents
    • Agrochemical pre-cursors
    • Photoinitiator raw materials

    5. Corrosion Inhibitor Additives: Oilfield and Industrial Water Treatment

    Formulators in oilfield chemistry and industrial water treatment adopt this aromatic acid as a co-component or precursor in corrosion inhibitor blends, where its aromatic structure aids in protective film formation on steel and alloy surfaces. Inhibitor packages require reliable purity to minimize side reactions or deposition in recirculating water and oil systems.

    Industry compliance standards

    • API RP 682/752 for chemical additives in hydrocarbon processing plants
    • ASTM D2757 for corrosion inhibitor chemical specification
    • ISO 14001:2015 for environmental impact control during blending
    • Material Safety Data Sheets (MSDS) disclosure as per GHS

    Typical usage ratio

    • 2–15% w/w of total inhibitor concentrate
    • Ratio set by required corrosion protection performance, metallurgy, and water chemistry

    Downstream process integration

    • Dosed in concentrate manufacturing by direct mixing in solvent blend
    • Subjected to compatibility and stabilization tests before drum filling
    • Monitored with analytical methods (HPLC/GC) to control batch uniformity

    Final product types

    • Oil drilling fluid corrosion inhibitors
    • Industrial closed loop water treatment additives
    • Steam system protective agent packages
    • Pipeline preservation chemicals
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    Certification & Compliance
    More Introduction

    4-Ethylbenzoic Acid: Practical Experience from a Dedicated Manufacturer

    Introduction to 4-Ethylbenzoic Acid and Its Model

    Our teams work with aromatic carboxylic acids every day, so 4-Ethylbenzoic Acid stands out as a straightforward and reliable intermediate in many chemical processes. The product we manufacture carries the model 4EBA-99, derived from our own numbering convention, reflecting its minimum assay of 99%. Over the years, consistent performance has proven more valuable to our customers than any flashy branding or packaging. Manufacturing 4-Ethylbenzoic Acid at scale demands strict control over reaction conditions, which brings real stability batch after batch for downstream applications.

    Technical Specifications Gained Through Direct Production

    On a typical production run, we use para-ethyl toluene as the main raw material and employ liquid-phase oxidation to form the acid group. Finished 4-Ethylbenzoic Acid leaves our reactors as a white crystalline solid. We monitor melting point, appearance, purity, moisture content, and trace impurity profile. In our experience, a melting point of 111-114°C, combined with GC-determined purity not less than 99%, gives end-users confidence for direct use in synthesis or formulation.

    Moisture remains a concern, especially during humid seasons. We routinely achieve less than 0.2% water content by Karl Fischer titration. Aromatic impurities, particularly related isomers and polynuclear compounds, are controlled through careful solvent selection and post-reaction purification. We have invested in closed-system drying and packaging—real-world lessons from years of rejected material due to moisture pickup or yellowing.

    Major Uses Observed by Manufacturers

    On the floor, most of our material goes into specialty chemical and pharmaceutical intermediates. Chemists value 4-Ethylbenzoic Acid because the ethyl group at the para position tunes reactivity while leaving the benzoic acid moiety accessible for functionalization. In esterification steps or amidation, this compound serves as a reliable coupling partner due to its predictable acid strength and relative purity attainable by recrystallization.

    We see steady demand from polymer additive producers, dye intermediates, and a few niche flavors and fragrance formulators. Direct feedback from these segments points to our product’s lower color index and stable composition even after several months. During scale-up, process chemists often remark on the compound’s high melting point, which makes solvent-system design simpler and reduces product loss.

    Key Differences from Other Substituted Benzoic Acids

    Manufacturers with experience in benzoic acids know not all substituted derivatives behave the same. 4-Ethylbenzoic Acid, due to its para-ethyl group, resists decomposition pathways that attack ortho- or meta-substituted analogs. This increases shelf life both in storage and in solution. Our product stows safely in opaque fiber drums or double polyethylene bags. From our own testing, the para orientation also minimizes contamination from difficult-to-remove isomers, reducing extra purification steps for customers.

    Comparing production lines, ortho- and meta-ethylbenzoic acids require additional steps after oxidation due to increased side-product, but with para isomer we run a more streamlined, single-tower crystallization that gives tight control over particle size and purity. These practical advantages matter most to downstream processors who want to cut costs on solvent, energy, and man-hours per kilo delivered.

    From the user side, 4-Ethylbenzoic Acid hydrolyzes cleanly and gives sharper melting and boiling points than similarly substituted acids such as 4-methyl- or 4-propylbenzoic acid. We observed that esters prepared from our 4-ethyl variant show greater stability and less odor compared to longer-chain analogs, which can oxidize or polymerize in storage.

    Lessons Learned About Handling and Quality

    In the early years, repeated shipments taught us how sensitive 4-Ethylbenzoic Acid can be to packaging and logistics. A batch that left the factory bright white could reach a customer yellowed by improper handling. Now, we use nitrogen-blanketed drums and recommend storage below 25°C. Close work with logistics partners has reduced claim rates dramatically and improved the reliability of supply. Laboratory analysis of retained samples from each lot allows us to trace and address every anomaly.

    Our quality team deploys HPLC, GC-MS, and Karl Fischer titration in each QC cycle. Before adopting these controls, complaints reached us regarding off-odors or sluggish reactivity in certain synthesis steps. Process improvement came from real failures and honest communication with formulators who were willing to share back detailed chromatographic data. Regular side-by-side comparisons with imported and domestic lots have shown us where not to cut corners, especially in post-synthesis drying and bulk packaging.

    Supply Chain and Sustainability Factors Direct from Operations

    As a plant-based chemical producer, we see every day how input purity affects 4-Ethylbenzoic Acid’s usability. Our raw materials come mostly from regional refineries and chemical plants. Over the years we have built up a supplier audit system, walking their floors, checking for mixed-tank storage or lapses in labeling. These hands-on inspections keep our own batches consistent and reduce the risk of contamination by heavier aromatics.

    We also face customer questions about the long-term safety and origin of our chemicals. At the manufacturer scale, it’s not feasible to overhaul every process overnight for environmental reasons, but we do track metrics for solvent recycling, waste reduction, and emission containment. For instance, our facility runs closed-loop cooling and recycles spent solvent into lower-grade products rather than incinerating. Responsibility grows from the ground up, so each lab tech, operator, and packager knows why tight process control matters not just for product quality but for surrounding communities.

    Downstream Chemistry Based on Plant Reality

    Lab chemists can read IR spectra all day, but application-level feedback guides much of our process control. Many small-molecule transformations rely on a regular flow of 4-Ethylbenzoic Acid for alkylation, condensation, or Friedel–Crafts reactions. In real-world runs, customers expect the product to dissolve smoothly in standard organic solvents like acetone or toluene, so we refine drying methods to ensure granules resist caking.

    By monitoring solubility data after every production lot, we reduce out-of-spec returns that plagued earlier years. Some users prefer a fluffier crystalline consistency for rapid dissolution, while others need tight particle size for automated feeders. Continuous communication with formulation chemists helps us fine-tune milling and post-drying conditions to match equipment downstream, limiting manual reprocessing at the customer end.

    Use in high-value pharmaceutical intermediates brings stricter impurity limits, so we’ve developed additional purification for those segments, even though it means lower throughput and higher costs per kilo. This focus improves reproducibility for sensitive synthesis such as API building blocks, where one trace impurity can slow or ruin a critical reaction step.

    Knowledge Gained Handling Bulk Orders and Custom Applications

    Bulk orders for 4-Ethylbenzoic Acid come with unique needs compared to kilo-lab work. Handling five-ton lots, we deal with static, bridging in hoppers, and the risk of airborne dust. Our team’s experience led us to fit all major transfer points with dust extractors. We train operators how to break up caked product safely and recognize changes in color or odor that signal process drift.

    Some buyers have custom requirements not found in chemical catalogues or databases. They may request finer or coarser grades, tailored moisture levels, or particular packaging types. Our plant adapts by introducing flexible drying cycles and installing extra sifting equipment for lot-to-lot adjustment. Direct feedback—both positive and negative—has steered us to phase out older packaging types that suffered from offgassing or cross-contamination.

    Transport brings its own challenges. In extreme climates, product can clump or color even during sealed shipment. We routinely add temperature loggers to outbound freight, and have developed a practice of pre-shipping retention samples to address any point-of-arrival issues. Years of listening—rather than forcing one specification on all buyers—helped build these routines.

    Real Challenges: Purity, Reproducibility, and Traceability

    No matter how reliable a production process, fluctuation can creep in at multiple steps. We found trace metal catalysts in raw material suppliers’ stocks a decade ago, which led to stubborn yellow byproducts in a handful of lots. Surveillance, both on-premise and with supplier partners, dramatically reduced recurrence of these defects.

    On occasion, supply chain disruptions drive up waiting times and complicate logistics—especially with global unrest or regulatory changes. The company maintains a small inventory buffer, which sometimes comes at a carrying cost, but repeated customer surveys show that buyers value continuity of supply above small shifts in price.

    From our quality management perspective, traceability means not just batch numbers, but having micro-samples archived and shipping documents kept digital and on hand for years. In sectors like pharmaceuticals or regulated polymers, this backtrace enables both us and customers to comply swiftly with audits and regulatory queries.

    Customer Collaboration and Continuous Improvement

    Direct working relationships with buyers drive real improvement far more than any sales brochure. In face-to-face visits or remote troubleshooting, end-users often spot trends earlier than a manufacturer’s own teams. Regular exchange of analysis data, as well as production feedback, guided us to adjust crystallization rates and add further controls on particle sizing.

    Our willingness to adapt comes from seeing how the tiniest process shift can matter down the chain—a new batch of catalyst, a minor humidity change, or a variation in storage can mean the difference between a repeat order and a costly recall. We foster a culture where plant staff feel empowered to halt production to maintain quality, rather than pushing through for quota.

    The customer success stories that reach us—faster synthesis, fewer filtration issues, more robust product finishes—demonstrate that attention to the small things matters most in real-world operations. These outcomes build trust and cut down on frustrating troubleshooting for both sides.

    Differences in Regulatory and Compliance Approaches

    Countries increasingly require detailed documentation and compliance for both human and environmental health. Our manufacturing facility keeps up with shifts in rules for restricted substances, maximum impurity levels, and safe handling guidelines. The documentation our plant generates—process logs, Certificates of Analysis, shipping manifests—flows from daily operations, not just for show.

    Audits, both announced and surprise, keep us vigilant for any slip in safety or environmental controls. We have shifted cleaning solvents, enclosed more process steps, and reduced open handling of finished acid based on real feedback from outside inspectors and regulatory updates. The underlying aim stays the same—stable, compliant chemical manufacturing without performance surprises for downstream users.

    Solving Ongoing Issues with Sourcing and Application

    In the field, we see how small changes in raw material quality can throw off whole runs. A shipment of less pure para-ethyl toluene causes incomplete oxidation and needs more aggressive purification, driving up both waste and labor. We now conduct incoming inspection on all major starting materials, even from trusted partners, to flag deviations early.

    Sometimes, open dialogue with users uncovers entirely new application concerns, such as compatibility with innovative resins or specific reactions for new pharmaceuticals. In these cases, we commonly support trial batches or further product characterization, even if it means reallocating plant time or offering small-scale samples. Supporting R&D efforts upstream and downstream benefits both sides, creating more loyal long-term customers.

    Process Economics, Efficiency, and Market Position

    Economics play an everyday role in manufacturing 4-Ethylbenzoic Acid. Our plant runs energy balances to benchmark against peer facilities, seeking ways to cut steam, electricity, or cooling water use without sacrificing product consistency. Through equipment upgrades and lean operations, we have trimmed costs per metric ton over time. This careful balancing enables us to offer steady pricing in the face of volatile raw material and fuel markets.

    The realities of market competition mean our product sits in a group with both large-scale multinationals and smaller specialty makers. The differences become clearest at the level of everyday reliability and the willingness to tackle unexpected technical requests or claims. We distinguish our product through transparency and tight feedback cycles—traits built up more from accumulated learning than from any marketing initiative.

    Summary of What Sets Manufacturer-Produced 4-Ethylbenzoic Acid Apart

    Manufacturing 4-Ethylbenzoic Acid as a primary producer brings daily exposure to the realities of cost, quality, traceability, and downstream utility. Technical consistency starts at the reactor and continues through drying, quality inspection, and hands-on packaging. Each batch reflects the lessons of years of collaboration, failed experiments, downgraded lots, and shared successes. The differences in performance, purity, and process efficiency compared to other benzoic acid derivatives prove crucial for customers aiming to streamline their own syntheses or formulations.

    In the end, more reliable lots, trusted documentation, and candid responsiveness to customer needs build ongoing relationships. Every shipment, lab report, and customer call gives our teams the information needed to fine-tune both product and process—ensuring that 4-Ethylbenzoic Acid produced in our facility remains not just a chemical, but a trusted tool for innovators across a range of industries.