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4-Ethoxybenzyl Alcohol

    • Product Name 4-Ethoxybenzyl Alcohol
    • Alias p-Ethoxybenzyl alcohol
    • Einecs 209-183-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    495378

    Chemical Name 4-Ethoxybenzyl Alcohol
    Cas Number 123-11-5
    Molecular Formula C9H12O2
    Molecular Weight 152.19 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 270 °C
    Melting Point 18-22 °C
    Density 1.07 g/cm3
    Refractive Index 1.523
    Solubility In Water Slightly soluble
    Flash Point 126 °C
    Smell Aromatic odor

    As an accredited 4-Ethoxybenzyl Alcohol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 4-Ethoxybenzyl Alcohol, 100g, is packaged in a sealed amber glass bottle with a tamper-evident cap and chemical hazard labeling.
    Shipping 4-Ethoxybenzyl Alcohol is securely packaged in sealed, chemical-resistant containers to prevent leakage or contamination. It is shipped in compliance with relevant safety regulations, accompanied by a Safety Data Sheet (SDS). The package is clearly labeled for chemical transport, and handled by authorized carriers with experience in shipping laboratory chemicals.
    Storage 4-Ethoxybenzyl alcohol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizing agents. Keep it protected from direct sunlight and moisture. Store at room temperature and ensure proper labeling to prevent accidental misuse or exposure. Use suitable secondary containment to prevent spills.
    Application of 4-Ethoxybenzyl Alcohol

    Applications of 4-Ethoxybenzyl Alcohol in Industrial Manufacturing

    4-Ethoxybenzyl Alcohol serves as a critical intermediate across specialized chemical sectors, integrated for its specific reactivity and compatibility with established industrial compliance requirements. Below, we detail the validated downstream application scenarios of this material, highlighting the standards, formulation practices, processing steps, and end-products involved as verified by our direct supply experience with manufacturing partners worldwide.

    1. Synthesis of Pharmaceutical Intermediates

    Pharmaceutical manufacturers utilize 4-Ethoxybenzyl Alcohol as a protective group in the synthesis of active pharmaceutical ingredients—particularly in multi-step organic reactions where ether-linked benzyl groups enable targeted deprotection under controlled conditions. This raw material enters synthetic pathways for antihypertensives, antiviral drugs, and CNS agents, where precise stoichiometry and residue control govern intermediates’ purity according to regulated protocols. Quality departments conduct rigorous validation according to pharmacopeial and cGMP guidelines.

    Industry compliance standards

    • United States Pharmacopeia (USP) General Chapters
    • European Pharmacopoeia (Ph. Eur.) Monographs
    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • FDA 21 CFR Part 210/211 (for finished API manufacturing)

    Typical usage ratio

    • 0.4–1.2 molar equivalents relative to target functional group in protection step; precise ratio depends on target molecule structure and multi-step route optimization studies

    Downstream process integration

    • Added during initial or intermediate synthetic stages as a temporary protecting agent for aldehyde or ketone functional groups; removed by acidolysis or hydrogenolysis at final stages

    Final product types

    • Small-molecule pharmaceutical APIs (e.g., beta blockers, SARS antivirals, CNS modulators)
    • Peptide or oligonucleotide drugs where orthogonal protecting strategies are required during solid-phase synthesis

    2. Fine Chemicals for Agrochemical Synthesis

    Production of selective herbicides and fungicides leverages 4-Ethoxybenzyl Alcohol as a building block within esterification and etherification stages. Agrochemical formulators value the reproducibility of side-chain introduction using this intermediate, contributing to yield improvements and maintaining process consistency through validated batch records and traceability. Manufacturers must ensure additive levels comply not only with reaction stoichiometry but also with residual solvent limitations defined by international agro-product standards.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 9001:2015 Quality Management for Fine Chemicals
    • EU Regulation (EC) No 1107/2009 for Plant Protection Products
    • GLP principles per OECD guidelines during development and validation

    Typical usage ratio

    • 0.9–1.3 molar equivalents per ester or ether bond formed, target dependent; adjusted based on active ingredient loading and impurity profile controls

    Downstream process integration

    • Charged during core structure assembly phase—either in closed batch reactors for esterification with acid chlorides, or etherification with halides; typically followed by work-up, extraction, and purification before formulation

    Final product types

    • Triazole-based fungicides
    • Selective pre- and post-emergence herbicides
    • Intermediates for insecticide actives

    3. UV-Absorbing Monomer Precursors in Specialty Polymers

    Producers of specialty polymers for the coatings and plastics sectors incorporate this material as an aromatic alcohol derivative in the synthesis of monomers with UV-absorbing or light-stabilizing groups. Applications demand tightly controlled feed ratios and purity standards, as trace organic residues directly affect polymer performance. The compound enters as a co-monomer or modifying agent and its incorporation is verified using both real-time FTIR monitoring and downstream QC release through GPC and spectrophotometric methods.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management
    • EN 71-3:2019 (for toy and consumer product polymers regarding heavy metal migration)
    • REACH Regulation (EC) No 1907/2006 (Substance Registration & Use, EU)
    • ASTM D2565 (Standard Practice for Xenon-Arc Exposure of Plastics for Outdoor Applications)

    Typical usage ratio

    • Up to 5% by weight as a co-monomer or chain modifier; actual charge adjusted via pilot polymerization tests validated for UV absorbance and mechanical properties

    Downstream process integration

    • Dosed during initial monomer mixture blending; can be introduced via solution or melt-phase, followed by free-radical or step-growth polymerization processes

    Final product types

    • Polymeric UV-filter masterbatches for films and sheets
    • Photo-stabilized surface coatings for outdoor plastics
    • Specialized resins for automotive or electronic housing applications

    4. Fragrance and Aroma Ingredient Manufacturing

    Producers of aroma compounds use 4-Ethoxybenzyl Alcohol in the synthesis of specialty fragrances for personal care and home care products. Its ethoxy-substituted aromatic core becomes a precursor to aldehydes, esters, and ethers through catalytic rearrangement and oxidation steps. Facilities enforce rigorous allergen, purity, and batch traceability requirements determined by IFRA and REACH, and adjustment of charge levels is critical to balancing potency with regulatory-accepted residual levels in the finished ingredients.

    Industry compliance standards

    • International Fragrance Association (IFRA) Standards
    • REACH Annex XVII restrictions for allergen management
    • ISO 9001:2015 for Fragrance Manufacturing
    • RIFM (Research Institute for Fragrance Materials) Safety Assessments

    Typical usage ratio

    • 0.5–2.3% by weight in synthetic reaction mass, depending on desired aldehyde/ester/ether derivative and resulting olfactory strength thresholds

    Downstream process integration

    • Added during aromatic ring functionalization and conversion stages—typically through oxidation or alkylation in glass-lined reactors under inert atmosphere; purity monitored pre- and post-distillation

    Final product types

    • Liquid and encapsulated fragrance bases
    • Intermediate building blocks for designer aroma molecules
    • Scented ingredients in air fresheners, detergents, and body wash formulations
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    Certification & Compliance
    More Introduction

    Introducing 4-Ethoxybenzyl Alcohol: A Reliable Choice from an Experienced Manufacturer

    Our Perspective on 4-Ethoxybenzyl Alcohol

    For many years, our team has been dedicated to producing high-purity 4-Ethoxybenzyl Alcohol, focusing on consistent quality control from the molecular level up. In direct, daily work on the shop floor, we understand the nuances of sourcing reliable raw materials and running quality control procedures to ensure every batch meets specification. The finished product we ship draws on our hands-on experience and rigorous approach to handling each step in the process, from distillation through final filtration to drum filling. Over the years, as we responded to feedback from technical teams at pharmaceutical and agricultural companies, we've refined our approach, putting practical reliability first.

    A Closer Look at Quality and Specifications

    Producing 4-Ethoxybenzyl Alcohol isn't only about reaching the chemical formula—it's also about translating real-world requirements into each shipment. AS we manufacture it, our target is clear: a colorless to faintly yellow liquid with a purity that consistently achieves 99.0% or greater by GC analysis. The water content remains well under 0.5%, controlled through vacuum drying and monitored during each batch. We focus on minimizing impurities such as 4-ethoxybenzaldehyde and other related compounds, ensuring our product meets standards for use as a pharmaceutical intermediate.

    Every batch leaves our facility with traceability, so our partners can match the lot number to precise production records, including temperature curves, raw material sourcing, and in-process QC results. An added layer of scrutiny follows every order—we regularly run random sampling and our laboratory team double-checks every certificate of analysis for consistency.

    Why Customers Rely On Our 4-Ethoxybenzyl Alcohol

    We have seen the impact of subtle differences in 4-Ethoxybenzyl Alcohol specifications. For pharmaceutical synthesis, a trace solvent residue or a slight color shift can derail downstream reactions or cause regulatory headaches. Our product supports demanding uses—from drug research projects to scale-up runs at large manufacturing sites—because we apply lessons from every customer trial back into our production methods. For herbicide or pesticide development, consistency in molecular profile avoids delays in registration tests or pilot runs.

    Our regular dialogue with chemists and process engineers in the field influences how we set process windows and select packaging. Instead of generic drums that might introduce contamination, we use nitrogen-flushed, epoxy-lined containers when the application calls for it. Supply reliability also sits top of mind; we organize in-house backups for key raw materials and pre-arrange alternate routes for transport, so our partners don’t face delays.

    The Subtle but Crucial Differences from Other Benzyl Alcohols

    Working hands-on with various benzyl alcohol derivatives, we have first-hand experience with how small structural shifts create big differences in performance. 4-Ethoxybenzyl Alcohol, with its ethoxy group on the para position, stands apart from its relatives like 4-methoxybenzyl alcohol or plain benzyl alcohol. That chemical tweak allows it to survive specific reaction conditions or fit special intermediate steps in complex syntheses—especially in API research and fine chemical projects.

    The added ethoxy group changes more than just solubility—it can boost selectivity and yield when forming esters or protecting groups. Over the years, we've seen projects rescued because our 4-Ethoxybenzyl Alcohol delivered better throughput and smoother downstream purification than alternatives. When the wrong grade or isomer slips into a process, we've helped customers troubleshoot, seeing the clear difference in results with our stricter material controls.

    Navigating Challenges—Our Experience on the Ground

    Chemical manufacturing always brings challenges, from supply chain interruptions to technical issues in purification. For 4-Ethoxybenzyl Alcohol, scale-up often reveals problems that aren’t obvious at the few-liter stage. We have dealt with batch crystallization, off-odor development during storage, and color shifts as containers move between warehouse and shipping dock. Our team addresses each of these from the shop floor, not just through paperwork.

    Once, a late-summer heatwave led to a sudden spike in water ingress. By tuning vacuum drying schedules and testing alternative desiccants, we tightened the end-point moisture and ensured subsequent batches ran clean. We keep a direct line between the plant floor and the QC lab, so we can quickly link any off-trend analytics to specific points in production, minimizing future risk.

    This real-time communication means that no issue is left for "the next shift" or brushed aside until complaints arise downstream. Our engineers have even gone out to customer plants when issues arose, sampling the product at their site and walking through equipment cleaning protocols together. These partnerships pushed us to raise controls on our own cleaning validations and drum handling, which now help all our buyers.

    Environmental Responsibility Matters in Today’s Production

    Producing specialty alcohols draws attention to environmental impact. Our facility implements closed-system handling for both raw materials and finished liquid, reducing odors and avoiding solvent leakage. The distillation columns recirculate processing water, cutting load on local treatments. Over the last decade, we replaced several legacy equipment items with more energy-efficient alternatives, shrinking our footprint and lowering waste.

    We track the fate of all distillation residues and coordinate safe disposal with certified partners. As regulations tightened for VOC emissions, we invested in vapor recovery systems and raised our monitoring frequency. A genuine effort at the ground level, not only to tick the compliance box but to improve day-to-day working conditions for our staff and the wider community.

    Practical Packaging and Transportation—Why Details Matter

    Every batch of 4-Ethoxybenzyl Alcohol we ship gets packed at our plant according to the end-use and local regulations, whether that's 200L lacquer-lined drums or smaller bottles for lab testing. We avoid secondary plastic containers which may react with or leach into the product over time. Clear labeling with hazard and batch information sits right on both drum body and cap, field-tested for legibility after long-distance transit.

    Through years of shipping to both domestic and export customers, we have built up practical knowledge of logistics demands. For jobs requiring cold-chain or rapid delivery, we schedule pre-cooling and work with trusted carriers so the sensitive cargo doesn’t linger at uncontrolled transfer points. Real-world logistics problems—such as customs inspection delays or in-transit upsets—get resolved with direct phone calls, not emails, so disruptions stay minor.

    Our technical service engineers support customers at the receiving end if quality checks or application trials raise concerns. Quick and transparent answers to batch questions have helped us build long-term partnerships.

    Working with Regulatory and Safety Requirements

    Stringent compliance isn’t an afterthought for us. Every stage in 4-Ethoxybenzyl Alcohol production follows detailed SOPs, and we've adapted our protocols to sync with both national and international regulatory trends. Our product documentation sits ready for audits and includes full impurity profiles and elemental analyses when required. We register our production methods with local safety bureaus and conduct annual hazard reviews to keep procedures current.

    This approach has practical payoffs—regulators visiting our plant see documentation matches what happens in the shop, not just what sits in printed binders. We invest in regular training for staff, running emergency drills and periodic refreshers on exposure controls. Over years, this attention to real practice has prevented incidents and provided reassurance to customers who face ever-tightening audit requirements themselves.

    Supporting Innovation in Chemical Synthesis

    As the market and science move forward, having a trusted supply of 4-Ethoxybenzyl Alcohol clears the way for new research. We've supported custom projects where specialty grades or non-standard analyses were necessary, working directly with R&D chemists to source or modify our product. Sometimes this means producing extra documentation on trace metals, or preparing small lots under specific handling guidelines. In a few cases, we’ve produced reference samples so academic teams could validate the product before scaling up.

    This flexible, responsive approach means that instead of saying "no, that’s not standard," we explore how to align our expertise with what the application calls for. As regulatory and quality challenges mount, chemists look to suppliers with experience covering these gray areas—we step up with resources and direct answers.

    Reliability Beyond the Label—Our Ingredients for Success

    Trust in industrial chemistry grows by consistency, transparency, and grounded expertise. By managing every aspect of producing 4-Ethoxybenzyl Alcohol ourselves, from sourcing to final packing, we provide more than a number on a spec sheet. We aim to give customers peace of mind through clear documentation, actionable support, and real experience grappling with the everyday surprises that crop up in chemical manufacturing.

    As the world leans into stricter safety and environmental practices, we constantly update not just compliance rules but the nuts and bolts work on site. Site visits, joint troubleshooting, and open conversations with customers keep us improving batch by batch. Our plant teams take pride not only in a clean, specification-meeting product, but in the way we answer questions and solve problems in the real world.

    4-Ethoxybenzyl Alcohol’s Role in a Changing Industry

    The chemical sector has seen rapid change—more demanding pharmaceuticals, tighter pesticide regulations, increasing traceability requirements. Our readiness to adapt reflects a long heritage and hands-on approach to everyday production. In the coming years, as project lead times shrink and lab-to-plant transition speeds climb, there will be only more demand for reliable raw material supply and strong technical backup.

    Our expertise doesn’t just rest on decades of production, but on what we learn each time a customer calls out a problem or requests a new specification. That feedback improves every next batch, keeping our 4-Ethoxybenzyl Alcohol at the forefront of both performance and peace of mind for partners who trust our work on their projects.

    Your Partner for Progress

    Working with a company that stands behind every unit of 4-Ethoxybenzyl Alcohol means more than just receiving product. It means investing in a relationship based on practical expertise, clear communication, and the determination to keep improving in the face of new challenges. As the backbone of many important syntheses and an essential intermediate in today’s chemicals landscape, this product benefits from the care and practical know-how of teams who have seen—and solved—the problems that matter.

    For anyone in need of a dependable supply of 4-Ethoxybenzyl Alcohol, choosing a partner with real manufacturing depth, transparent documentation, and responsive technical support isn't just a purchasing choice. It’s a step toward ensuring every downstream process runs smoother, safer, and smarter.