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4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone

    • Product Name 4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone
    • Alias N,N-Diethyl-p-(phenylhydrazono)benzaldehyde
    • Einecs 218-734-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    341880

    Chemical Name 4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone
    Molecular Formula C23H25N3
    Molecular Weight 343.47 g/mol
    Appearance Yellow to orange crystalline solid
    Cas Number 2207-91-4
    Melting Point 181-183°C
    Solubility Soluble in organic solvents such as ethanol and chloroform; insoluble in water
    Storage Conditions Store at room temperature, protected from light and moisture
    Synonyms N,N-Diethyl-4-formylbenzenamine 1,1-diphenylhydrazone
    Purity Typically ≥98%
    Application Used as an analytical reagent and intermediate in organic synthesis

    As an accredited 4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 10 grams of 4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone, with hazard labeling and tamper-evident seal.
    Shipping The chemical 4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone is shipped in tightly sealed containers, protected from light and moisture. It is packed following standard safety protocols for stable organic compounds, labeled correctly with hazard information, and shipped via approved chemical transport carriers in compliance with local and international regulations.
    Storage **4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone** should be stored in a tightly sealed container, protected from light and moisture, and kept at room temperature in a well-ventilated, dry area. Avoid sources of ignition and strong oxidizing agents. Ensure proper labeling and segregation from incompatible substances. Storage conditions should minimize exposure to air and heat to maintain stability and purity.
    Application of 4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone

    Applications of 4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone in Industrial Manufacturing

    4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone serves as a functional chemical intermediate in several advanced manufacturing sectors. This material delivers specific performance criteria for select downstream formulations in colorimetric analysis, specialty pigment synthesis, and diagnostic reagent preparation, where regulatory compliance, process consistency, and technical specifications remain tightly managed. We control synthesis and QC parameters to match client integration needs, ensuring traceability and consistency across all production batches.

    1. Analytical Reagent Formulation for Spectrophotometry

    This hydrazone compound acts as a chromogenic reagent for transition metal and rare earth quantitation in both environmental and pharmaceutical analysis laboratories. Laboratories directly incorporate it into analytical kits, using its selective chelation and colored complex formation for endpoint detection in spectrophotometric workflows. It supports analysts in developing highly sensitive detection protocols where regulatory agencies require trace impurity quantification.

    Industry compliance standards

    • ISO/IEC 17025 for laboratory quality systems
    • OECD Guidelines for the Testing of Chemicals
    • European Pharmacopoeia (Ph. Eur.) 10.0 Section 2.2.25 for absorbance measurement

    Typical usage ratio

    • Formulation level typically between 0.2–2.0 mg per sample cuvette (10 mL), adjusted based on target analyte and detection limits

    Downstream process integration

    • Added at the dye-reagent compounding phase; diluted to working strength immediately before use; incorporated into single-use test kit assembly lines

    Final product types

    • Colorimetric metal analysis kits
    • Pre-measured laboratory test vials
    • Analytical standards

    2. Intermediate for Specialty Organic Pigment Synthesis

    Downstream pigment manufacturers employ this compound as a coupling agent during the preparation of diazo-based dyes for plastics, high-performance inks, and specialty coatings. Its defined reactivity and electronic properties allow for precise shade modification in multi-stage pigment synthesis, directly impacting color strength and fastness attributes critical for industrial paint and coated product applications.

    Industry compliance standards

    • EN 71-3:2019 for heavy-metal migration in colorants
    • REACH Annex II (EC) No. 1907/2006 for chemical registration
    • ASTM D476 for titanium dioxide pigment quality (used in formulation blends)

    Typical usage ratio

    • Commonly dosed at 1–5% by mass relative to primary pigment precursor, ratio optimized according to desired hue and pigment performance

    Downstream process integration

    • Introduced at the diazotization or azo-coupling stage in closed reactor systems; post-coupling purification step followed by blending with pigment dispersants

    Final product types

    • Organic pigment concentrates for coatings
    • Plastic masterbatches
    • Inks for industrial printers and packaging

    3. Diagnostic Test Reagent Manufacturing

    Producers of in vitro diagnostic devices and clinical test strips use this hydrazone derivative as an indicator for colorimetric detection of biomolecules, including specific proteins and metal ions. It plays a critical role in the final reagent mix, supporting reliable color development and results interpretation for point-of-care testing. Accurate dosing is essential to maintain diagnostic accuracy under ISO-conformant manufacturing.

    Industry compliance standards

    • ISO 13485 for medical device QMS
    • 21 CFR 820 FDA QSR for diagnostic device manufacturers
    • IVD Directive 98/79/EC for European market

    Typical usage ratio

    • Typically formulated at 0.01–0.1% w/w in diagnostic strip indicators or solution phase tests; content adjusted according to target analyte and test strip design

    Downstream process integration

    • Incorporated into final indicator mix during reagent compounding; applied to substrate or stored in reagent wells during test strip assembly and lamination stages

    Final product types

    • Blood test strips for clinical chemistry analyzers
    • Urinalysis POC strips
    • Metal ion screening cassettes

    4. Chemical Research Reference Material Production

    Reference standard producers utilize the compound in the synthesis and certification of analytical standards for complex matrix calibrations. It is dissolved, characterized, and aliquoted in controlled environments, supporting reference labs and contract testing organizations in validating chromatographic or spectrophotometric methods per international guidance. Batch traceability, purity verification, and documentation conform fully to reference material quality frameworks.

    Industry compliance standards

    • ISO 17034 for reference material producers
    • ISO Guide 35 for reference material characterization
    • USP General Chapter <30> for reference standards

    Typical usage ratio

    • Prepared as 1–100 mg/L in solvent/certified solution format; aliquots determined per analytical method validation requirements

    Downstream process integration

    • Enters at the reference solution compounding phase; precise weighing, dissolving, and sub-packaging carried out; final product filled under inert conditions in pre-cleaned vials

    Final product types

    • Certified calibration standards for UV/Vis spectrophotometry
    • Traceable organic reference mixtures
    • Stability test controls for laboratory QA/QC

    5. Additive for Photographic Chemical Processing

    Manufacturers of specialty photographic chemicals add this hydrazone as a key component in color developer solutions used for high-resolution imaging film and paper. It acts as a color-forming agent through selective interaction with developed silver halide crystals, enhancing dye layer sharpness and image density while maintaining compatibility with automated wet process systems. Production requires consistent batch reactivity and solution purity.

    Industry compliance standards

    • ISO 1891 for photography processing solutions
    • RoHS 2011/65/EU for restriction of hazardous substances in imaging products
    • ANSI IT9.2 for stability of photographic processing chemicals

    Typical usage ratio

    • Formulated at 0.05–0.5% by weight in color developer baths, dependent on film or paper type and targeted color intensity

    Downstream process integration

    • Added during developer concentrate compounding; quality tested for color yield and stability before bottling; used by imaging labs in automatic film processors

    Final product types

    • Color developer concentrates
    • Single-use color developing chemicals
    • Professional photographic print kits
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    Certification & Compliance
    More Introduction

    4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone: A Closer Look at Our In-House Synthesis and Its Practical Value

    Understanding What We Make and Why It Matters

    Having spent decades hands-on in chemical synthesis, we've seen the landscape shift and mature—accuracy and control have moved from luxuries to expectations. 4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone represents a fine-tuned product from our core facility, embodying the habits of precision and reliability we have locked into every step of our production process. Our team approaches each batch as both an exercise of skill and a point of pride, not only because it demonstrates our technical expertise, but because researchers and manufacturers depend on a steady, reliable supply of quality hydrazones.

    We don't see this as just another specialty chemical; it’s a material that brings together purity requirements and process scalability in a way that few other hydrazones offer. Our on-site chemists handle every stage: sourcing the right grade benzaldehyde, managing the diethylamino substitution, and running continuous quality checks to keep impurities down to the strictest thresholds needed for research and high-value synthesis. Every production run means another deep-dive into solvent choices, temperature holds, and reaction yields to make sure the identity and quality remain consistent from batch to batch—a demand that gets put to the test with every research order and every manufacturing scale-up.

    Model and Specifications Born From In-House Experience

    Every model we ship ties back to a foundation poured with practical lessons from failed reaction trials and successful scale-ups. Our technical documentation doesn’t come from a reseller’s shelf but from work at the reactor, balancing the right molar ratios and adjusting purification steps for the best yield. Typical physical characterization shows a pale-yellow solid, confirming our process routes and cleanup steps hold up well under varying ambient temperatures.

    We don’t ever compromise on water content or residual starting material, and that isn’t just about checking a QC box—it is about repeatable, credible results in every downstream process our partners run. Each lot receives a certificate of analysis that reflects actual batch data from our QA lab. Practically, this means you’ll see batch-to-batch stability in colorimetric applications, predictable solubility, and zero drift in the hydrazone’s reactivity under standard organic reactions. Labs working with us have pointed out how our lots allow them to skip extra purification steps and move straight to their main targets, saving hours of prep per cycle.

    Value in Synthesis, Analysis, and Application

    Since the core structure features a diethylamino group at the para-position, the electron-donating effect sets its reactivity profile apart from other benzaldehyde hydrazones. Chemists in organic synthesis recognize how this pushes certain nucleophilic additions and coupling steps forward that otherwise stall or give weak conversions with unsubstituted variants. The versatility finds a home in analytical chemistry too, especially in photometric methods for detecting aldehydes and ketones, with the diethylamino substituent helping sharpen response signals in colorimetric analysis.

    Repeated feedback from development chemists points to real advantages: more predictable coupling yields, sharper endpoint identification in titration work, and less background noise across UV-Vis scans. Our product has also found its way into research around azo dye intermediates and specialty pigment work, fields where stability during synthesis and post-reaction purity both make measurable impacts on commercialization results. End-users avoid product variability, sidestep unnecessary downstream filtration, and gain the reliability needed for regulatory compliance in larger-scale applications.

    Real Differences from Similar Products

    Comparisons with standard benzaldehyde hydrazones reveal clear contrasts. The diethylamino group’s presence on the aromatic ring isn’t there to check a box; chemists using more basic hydrazones have often reported sluggish reaction rates or inconsistent color development in analytical procedures. Our product’s stability against light and atmospheric moisture also limits the need for special handling or ultra-tight packing. Analysts often tell us they waste fewer vials, and process operators pull fewer rejects when switching to our hydrazone product.

    Another difference is shown in the way our synthesis avoids side reactions. Many commercial samples bring traces of over-reacted or decomposed by-products, which creep into analytical baselines and manufacturing outcomes. We’ve worked through decades of batch notes and failure analyses to focus our work-up so that our lots contain minimal background signal in analytical procedures. The enhancement in shelf-life and signal clarity stems directly from these efforts. In pigment synthesis and analytic workflows, losses tied to off-color product or batch rejection shrink considerably.

    Direct competitors may supply generic hydrazones on a stocking model, but they often lean on intermediaries rather than hands-on production. We don’t work with faceless subcontractors trading off data sheets; every kilo stamped with our label left our own reactor. When working up a new synthesis path, our chemists run side-by-side comparisons with industry benchmarks, recording not only yield and purity but real-world usability in established customer protocols.

    Our Production Approach: Putting Theory Into Everyday Practice

    Manufacturing real-world chemicals at scale means much more than just running a reaction from a textbook. Raw material quality shifts with seasons and supply themes—our QA team runs identity and purity checks on every input lot to stop process drift before it starts. Our on-floor operators check reaction exothermicity and maintain control of solvent additions meticulously, recording each parameter for traceability. What leaves our facility has crossed a checkpoint for moisture, appearance, melting point, and GC purity, with nothing sent out without human review.

    Our internal process knowledge builds from previous years, so we don’t treat each batch as a one-off. Small trial runs, feedback sessions with formulation labs, and full-scale manufacturing all tie back to the same operating principle: consistency drives trust. We shut down lines to troubleshoot even minor deviations, knowing real customer processes hang in the balance. Each product lot blends the best practices in temperature control, pressure monitoring, and reagent handling, reflecting technical standards and practical production sense learned through real incidents.

    Feedback-Driven Adjustments and Continuous Improvement

    One area where our approach stands out involves how we incorporate field feedback into process adjustment. Organic chemists working on scale-up have credited our hydrazone with speeding up their own purification steps, cutting grit in their chromatography columns and letting them reclaim product otherwise lost in earlier bottlenecks. Every season brings a new round of dialogue between our QA chemists and real customers—what worked, what created a challenge, what needs a new look.

    Several years ago, we switched to a new solvent system after field engineers found that residues from the legacy process led to signal disturbances in their high-resolution analysis instruments. Rather than holding onto sameness out of habit, we rebuilt our solvent addition and recovery stages, dropping contaminant levels below sensitive detection limits. Process logs from our facility detail those changes in batch documentation, providing direct proof for labs that require full traceability when certifying their own production processes.

    Usage Insights and Application Scenarios

    4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone works best where stable, obvious endpoint detection and robust color formation matter. Synthesis teams in pharmaceutical research rely on its electron-rich structure during complicated multistep reactions, finding that our tightly controlled process leads to fewer purification headaches down the line. Analytical chemistry teams value the strong absorbance response in UV-Vis methods—unlike less substituted analogues, which sometimes require extra derivatization.

    This hydrazone’s well-defined structure and low impurity profile have drawn attention in efforts to develop new organic ligands and in development work on functional dyes. Each unique customer requirement generates a conversation: Should the product be shipped under strict light protection, or does standard amber glass suffice? Does the researcher need particle-size data for thin-layer diffusion studies, or will bulk purity play the larger role? Our process group responds directly with targeted release parameters, not off-the-shelf checklists.

    We’ve seen demand driven not only by established industrial users but also emerging technology firms experimenting with new detection devices, colorimetric diagnostic tools, and even educational laboratories eager for stable, easy-to-handle demonstration materials. Some institutions highlight that our product bridges a stubborn gap between research-scale curiosity and manufacturing-scale reliability—making it possible for process innovation teams to move from milligram to kilogram scale without retooling downstream checks.

    Committed to Real Transparency and Rigorous Traceability

    Trust in a chemical supplier doesn’t come from fancy packaging or just-in-time delivery. Our customers rely on transparent documentation, open doors for technical support, and raw lab data to back every batch. Whether a small startup or a global manufacturer, researchers and operators alike can walk through our facility audits—scrutinizing process records down to batch signatures and frequency of in-process controls.

    During global supply stresses, we kept production rooted at our site, avoiding dilution of accountability to shadow factories or anonymous fill-and-finish vendors. Every lot that leaves us can be traced back stepwise to its raw material origins, a clear asset for customers seeking robust regulatory compliance or those subject to internal audit. In an industry brimming with relabelers and speculators, we stick to what we know: hands-on chemistry and direct accountability.

    Breaking Down Typical Issues and Solutions That Matter

    A recurring issue with hydrazones sourced from third-party aggregators involves shadow impurities that slip through basic functional tests but emerge under higher-order analytical scrutiny. We’ve addressed this not only with better purification, but also with long-haul stability stress testing, improving ironclad storage protocols and revising container guidelines for end-users to avoid contamination. Avoidance of trace acid or oxidizer residuals has led to stronger customer outcomes, especially in high-sensitivity analytical workflows.

    Another problem many laboratories face comes from uncertain batch identity—from suboptimal labeling to cut corners on integrity checks. Our batches move with exhaustive paperwork—COA, batch ID, and retention samples, maintained in cold storage for customer reference whenever post-delivery questions arise. This degree of diligence allows production teams downstream to audit their own outcomes, trace back triggers for process drift, and tune their own quality checkpoints based on real-world batch behavior.

    Even small differences in by-product residuals or water content can shipwreck high-value synthesis. We recognized this years ago and subsequently invested in moisture meters, Karl Fischer titration systems, and expanded analytical chromatography. Our technical team works directly with customers to troubleshoot the odd outlier—adjusting storage advice, rush-ordering replacement product, and, where merited, running parallel production just to match customer-specific requirements in a matter of days.

    Supporting Innovation with Consistent Chemistry

    Each year, we see our hydrazone play a role in emerging research areas—new sensors, inventive dye chemistry, even material science education kits. Our research partners count on the reliability of our product’s spectral features and purity to validate their own innovations without surprises from the starting materials. Startups and academic groups gravitate toward our compound because it matches their message of process safety and method repeatability, which are critical in winning external validation on new inventions.

    We encourage collaborations, opening up our methods for academic peer review and direct sourcing discussions. Technical questions face answers from qualified chemists, not scripted service agents. This culture—a blend of blue-collar manufacturing know-how and transparent scientific rigor—has earned us a spot as collaborators rather than just vendors, connecting us with the next wave of research and process design.

    Building on Lessons Learned for a More Reliable Tomorrow

    Innovation, at its heart, springs from a foundation of reliability. We place 4-(Diethylamino)Benzaldehyde-1,1-Diphenylhydrazone at the center of a feedback-rich production loop. Our successes trace back not just to market demand but to painstaking attention to every process parameter, every impurity profile, and every user’s challenge. As process chemistry sharpens and analytical methods evolve, we stay agile, applying each lesson learned in the field to future batches and, in turn, to the confidence of our end-users.

    Summary of What Sets Us Apart

    With roots deep in hands-on chemical production and a track record of measurable consistency, we provide more than just a shelf product. Our customers find fewer analysis headaches, better process yields, and direct access to technical feedback and support. In a crowded market where chain-of-custody can blur and accountability wears thin, we commit to transparent, responsible, forward-looking manufacturing.