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HS Code |
740082 |
| Name | 4-Cyanobenzaldehyde |
| Cas Number | 874-90-8 |
| Molecular Formula | C8H5NO |
| Molecular Weight | 131.13 g/mol |
| Appearance | White to off-white solid |
| Melting Point | 94-97°C |
| Boiling Point | 279°C |
| Density | 1.19 g/cm³ |
| Smiles | C1=CC(=CC=C1C#N)C=O |
| Synonyms | p-Cyanobenzaldehyde, para-Cyanobenzaldehyde, 4-Formylbenzonitrile |
| Pubchem Cid | 14447 |
| Solubility | Slightly soluble in water, soluble in organic solvents |
As an accredited 4-Cyanobenzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 4-Cyanobenzaldehyde is packaged in a 100g amber glass bottle, sealed, labeled with hazard warnings, and batch identification details. |
| Shipping | 4-Cyanobenzaldehyde is shipped in tightly sealed containers, protected from moisture and light. Packaging complies with regulatory guidelines for handling hazardous chemicals. Transport is typically via ground or air freight, with proper labeling and documentation. Appropriate safety measures are followed to prevent exposure, spills, and environmental contamination during transit. |
| Storage | 4-Cyanobenzaldehyde should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from direct sunlight, heat sources, and incompatible substances such as strong oxidizing agents. Keep the chemical away from moisture and minimize exposure to air to prevent degradation. Label the container clearly and ensure access is limited to trained personnel using appropriate personal protective equipment. |
Applications of 4-Cyanobenzaldehyde in Industrial ManufacturingAs the original producer of high-purity 4-Cyanobenzaldehyde, we ensure consistent material quality for industrial partners engaged in downstream manufacturing. This specialized aromatic aldehyde primarily enters highly regulated sectors as a key intermediate, participating in defined synthesis routes and subject to strict compliance standards. Below, we outline core application scenarios, including industry requirements, proportion recommendations, stage of process entry, and end product types recognized by global buyers. 1. Pharmaceutical Intermediate for Active Pharmaceutical Ingredients (APIs)Pharmaceutical manufacturers rely on 4-Cyanobenzaldehyde as an advanced intermediate during the synthesis of several API molecules, including antipsychotics and anti-hypertensive agents. In these pipelines, manufacturers must select and control reagent specifications to meet official regulatory frameworks in global healthcare markets. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Synthesis of Liquid Crystal Monomers for Display ApplicationsProducers of advanced display materials use 4-Cyanobenzaldehyde as a precursory building block when preparing specific liquid crystal (LC) monomers. Precise control over starting materials ensures the required optical and electrochemical properties in final LC mixtures deployed in TFT-LCD and OLED panels. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Agrochemical Intermediate: Synthesis of Plant Protection AgentsManufacturers of high-activity herbicides and fungicides use 4-Cyanobenzaldehyde as a critical raw material to introduce cyano-functionalized aromatic moieties, which contribute to bioactivity and selectivity in agricultural formulations. Strict adherence to regional agrochemical regulations governs sourcing and traceability in these processes. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Aroma and Fragrance Intermediate for Specialty Chemicals4-Cyanobenzaldehyde serves fragrance compound manufacturers as a specialty aromatic aldehyde for synthesis of unique nitrile-containing molecules, supporting high-purity aromatic solutions required by international cosmetic and household product brands. Regulatory expectations for restricted substances and trace residuals are especially stringent in this sector. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Specialty Dyes and Pigments IntermediateProducers of high-performance dyes and pigments introduce 4-Cyanobenzaldehyde as a tailored precursor in the manufacture of specific cyanine and azo dye classes. The presence of the cyano and formyl functional groups in the aromatic system enables vibrant, stable colorants used in demanding industrial coloration applications, where purity and consistency drive downstream QC protocols. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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Standing inside a plant where every batch of 4-cyanobenzaldehyde takes shape, you feel the pulse of decades’ worth of chemical process refinement. Over countless production runs, we focused on creating a material our clients rely on—the clear, pale yellow crystalline powder that chemists look for when their reactions demand purity and predictability. Our team’s insight grows with each batch. Before packing, you’ll see us test for trace impurities and moisture because real work in chemical synthesis—and in scale-up—never leaves room for guesswork.
We produce 4-cyanobenzaldehyde with the intention that each lot measures up to stringent standards. You will notice a melting point consistently spanning 48–51°C, easily checked in our labs. Its molecular formula, C8H5NO, stays non-negotiable. Our purity, measured by gas chromatography, averages above 99%. We settle for nothing less because we know impurities disrupt downstream reactions. Our approach means every drum, every kilogram, matches these specifications. Stable storage is part of our obsession—protection from light, sealed to avoid moisture, always with airtight liners that resist leaching or contamination.
Chemists buy 4-cyanobenzaldehyde for its tight melting point, fine granulometry, and distinct aromatic odor. These properties support fast, clean dosing into reaction vessels or automated feeders. I remind new staff that a single extra percent of water or a few ppm of iron throws off reductive aminations or Grignard additions. We routinely check for these pitfalls. Typical limits run below 0.2% moisture and undetectable metals. Every pack, from 100 grams to 25-kilogram drums, ships with a full certificate, not just because customers ask, but because we constantly monitor our lines for cross-contamination—learning from small mistakes before they become big ones.
Our regular customers in pharmaceutical R&D ask for 4-cyanobenzaldehyde when building active intermediates. You find it pivotal for synthetic routes in targeted molecules like sartans, and in custom ligand construction. It’s the aldehyde’s unique reactivity with nucleophiles and its stability across a range of pH values that unlock versatility in large and small-molecule discovery alike. Years ago, customers would bring us challenges—batches that clumped or discolored. It taught us not to shortcut quality in particle size control or packaging. Today, the same standards let our product run smoothly from glass vials to production reactors, saving hours on filter clogging and flask washing.
If you’ve tried swapping other benzaldehyde derivatives, you quickly learn what sets 4-cyanobenzaldehyde apart. The para-cyano group dramatically alters electron density at the formyl position. Reaction rates in condensation and addition chemistry come faster and cleaner compared to ortho or meta isomers. This isn’t just theoretical: in our own trials, 4-cyanobenzaldehyde regularly completes reactions several minutes ahead of similarly substituted aldehydes. As a bonus, the cyano group keeps the compound relatively immune to over-oxidation—a welcome advantage when scaling multistep syntheses. Side-by-side, our customers notice fewer byproducts, higher isolated yields, and simpler downstream purification than using unsubstituted or methoxy-substituted analogs.
Having worked with this material across seasons, we recognize where trouble can start. 4-cyanobenzaldehyde requires attention to proper ventilation, gloves, and goggles since fine dusts irritate airways and skin. Overheated conditions provoke slow decomposition, so our drum rooms stay climate-controlled, our suction lines checked weekly. More than a warning on a sheet, we train every operator to spot off-odors or visible yellowing at intake, since real safety starts with eyes and experience. Transportation relies on containers that hold up against rough handling—steel drums or HDPE kegs that don’t warp even in humid conditions.
Decades of running small pilot batches and commercial-scale lines have taught us that subtle quality differences ripple downstream. One contaminant brings headaches in crystallization. Variable particle sizes cause uneven flow in automated feeders. To avoid these pitfalls, we draw on feedback from production chemists: improving consistency batch after batch. Our 4-cyanobenzaldehyde has earned a place in mid-stage production precisely because reliability brings fewer stoppages, less rejected product, and faster process validation. We see it in customer retention, in the way purchasing managers re-order when quick turnarounds and traceable specs support their delivery schedules.
Each year, more of our buyers want to hear about waste reduction and greener processing. We respond by tightening solvent recycling and energy monitoring, tweaking reaction steps to minimize byproduct formation. In earlier days, inefficient workups and excess washing brought headaches in wastewater disposal. In recent years, we re-engineered steps to regenerate and reuse process solutions—not only lowering cost but meeting evolving environmental standards at every step. Customers often tell us these sustainability efforts have become key in qualifying suppliers, and we are glad to share real traceable improvements.
One common challenge comes during bulk handling. Aromatic aldehydes sometimes develop unwanted side products if exposed to air during long transfers. We invested in closed-transfer systems with nitrogen blankets to stabilize product freshness. This means you won’t see off-spec color or aroma changes at point-of-use, even months after manufacture. Another issue pops up during winter shipment: crystalline bridging can hinder dispensing. Our solution uses flow-enhancing liners and temperature-regulated storage, which cuts downtime and labor in customers’ operations. These small adjustments—none available off a generic spec sheet—come from direct dialogue with process engineers, not just standard “product improvement plans.”
Years ago, we fielded requests for finer particle sizes to speed up dissolving in pharmaceutical buildouts. We responded by retrofitting milling systems in our plant, testing batch-to-batch consistency until average size and flow properties matched what process techs needed. Later, another group pressed for stricter heavy metal controls as regulatory scrutiny increased. We added additional resin filtration and in-line analytics. Each adjustment made our 4-cyanobenzaldehyde one step better—direct answers to real-world production headaches. Product evolution happens because plant chemists, not just sales teams, listen directly to the folks making things out of every kilogram we ship.
Trust doesn’t come from certifications alone. It builds through day-by-day attention to detail: logging every heating ramp, charting impurity trends, and running hands-on training for new operators who handle toxicology samples and pilot campaigns alike. When partners tell us about sensitive pharmacophores or complex chiral intermediates, we recognize the confidence placed in our product. You might see a familiar name on a delivery drum, but what really supports each reaction is the invisible labor behind process validation and quality assurance that every operator on our line signs off on. We built our track record delivering what’s promised, every time.
Global standards for aromatic intermediates ratcheted up in recent years, with attention shifting from simple purity to things like residual solvent profiles, trace nitrosamines, and lifecycle documentation for each drum shipped. New scrutiny means that our analysts stay current on REACH, FDA, and ICH expectations. From batch labels to retained samples, we document every production variable—not because regulators demand it, but because unplanned events (shipments delayed at port, lab validation reruns) only get resolved when detailed lot histories are close at hand. We see our role as not just making a chemical, but safeguarding every pathway it supports, from research benches to API production lines.
We sit down with customers, not just exchange emails. We ask about unexpected color shifts, tricky handling environments, odd crystal growth during product recovery. It’s not lip service—customers’ process chemists, sometimes the shift crews who use our product day and night, spot problems we would never see from a distance. Those conversations prompted everything from tweaks in drying cycles to batch-specific re-screening. Getting granular with feedback means our product reflects your changing needs instead of lagging behind.
Disruptions hit every chemical producer, from strikes at shipping ports to spikes in demand for related aromatic intermediates. We build up raw material inventory buffers during quieter periods, keeping ample supplies of feedstock benzonitrile and reagents, so committed orders never face last-minute substitution. This way, we sidestep the scramble that comes with volatile market swings. Our internal teams run scenario drills for expedited shipping, alternate suppliers, or sudden changes in transport regulation. Consistent delivery matters, whether you run a kilo-scale pilot or supply a blockbuster’s production ramp-up. Each customer learns they can count on our schedule, season after season.
In the chemical manufacturing field, the real payoff doesn’t come from one-off deals but from repeated collaboration. Customers routinely involve us early in new project ramp-ups, sharing their timelines, purity targets, and batch-size ramp plans. We become partners, not just suppliers. Both sides save effort and cut error rates by sharing context, whether adjusting pack sizes or tightening specs. Our long-term clients often admit that what pulled them back wasn’t just chemical quality, but the ability to communicate openly, get quick fixes, and rely on answers that go beyond the obvious.
No process stands still. The push for better selectivity, solvent efficiency, and safer working environments influenced how we approach our core products. For 4-cyanobenzaldehyde, this means ongoing investment in greener chemistries, from reactive distillation steps that recover feedstocks to progress on finding lower-toxicity process aids. Our pilot teams evaluate catalyst options and synthetic routes every year. Small gains in energy efficiency or yield, multiplied by thousands of kilograms, leave a real mark on cost and environmental footprint alike.
We see the future of 4-cyanobenzaldehyde production as one tied to transparent quality practices, faster logistics, and responsiveness to evolving chemistry challenges. From new regulatory realities to the creativity of custom synthesis teams, the need for trustworthy, consistent materials only grows. Having stood in the shoes of those who make, use, and troubleshoot with these aromatic aldehydes, we shape each shipment to address genuine, not hypothetical, needs. Our ongoing investments, both in people and process, anchor our commitment to delivering 4-cyanobenzaldehyde that surpasses basic specification sheets—real-world quality for real-world chemistry.