|
HS Code |
184526 |
| Chemical Name | 4-Chlorobutyl Acetate |
| Synonyms | 1-Acetoxy-4-chlorobutane |
| Molecular Formula | C6H11ClO2 |
| Molecular Weight | 150.60 |
| Cas Number | 6933-97-1 |
| Appearance | Colorless liquid |
| Boiling Point | 204-206 °C |
| Density | 1.061 g/mL at 25 °C |
| Refractive Index | 1.417-1.419 |
| Flash Point | 86 °C |
| Solubility | Insoluble in water, soluble in most organic solvents |
As an accredited 4-Chlorobutyl Acetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | **Description:** 4-Chlorobutyl Acetate, 500 mL amber glass bottle, sealed with a PTFE-lined cap, labeled with hazard and handling information. |
| Shipping | 4-Chlorobutyl Acetate is typically shipped in sealed, labeled containers made of compatible materials, protected from light, heat, and moisture. It must be handled as a hazardous chemical, with shipping regulated according to local, national, and international transport regulations. Ensure compliance with all safety and documentation requirements for hazardous goods. |
| Storage | 4-Chlorobutyl Acetate should be stored in a tightly closed, clearly labeled container in a cool, dry, and well-ventilated area, away from heat, ignition sources, and incompatible materials such as strong oxidizers and acids. Store away from direct sunlight. Use appropriate secondary containment. Access should be restricted to trained personnel, and spill containment measures should be in place. |
Applications of 4-Chlorobutyl Acetate in Industrial ManufacturingAs the original manufacturer, we see 4-Chlorobutyl Acetate adopted in specialized sectors where its unique molecular structure and reactivity provide targeted process advantages. Below, we detail its proven integration across key downstream application areas, highlighting regulatory frameworks, formulation ranges, production steps, and the finished goods realized by industry clients. 1. Pharmaceutical Intermediate SynthesisIn pharmaceutical chemical manufacturing, 4-Chlorobutyl Acetate serves as a reliable intermediate for the synthesis of active pharmaceutical ingredients (APIs), notably those involving butyl side-chain modifications. Its balanced reactivity and acetyl protection facilitate controlled alkylation and esterification steps, essential for the preparation of certain antibacterial, antihypertensive, and central nervous system compounds. Process engineers incorporate this molecule during multi-stage API synthesis, benefiting from its stability under anhydrous conditions, enabling precision in constructing drug precursors with strict impurity profiles. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Agrochemical Synthesis (Herbicide & Fungicide Intermediates)4-Chlorobutyl Acetate is widely employed in agrochemical synthesis pathways as a critical intermediate, especially during the manufacture of functionalized butyl-side-chain herbicides and fungicides. Its acetoxy group offers effective temporary blocking for downstream nucleophilic substitution or cyclization steps. Formulators favor its use for producing intermediates with controlled reactivity, which ultimately ensures compliance with international crop protection standards for purity and environmental persistence. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Polymer Additives and Specialty PlasticsIn the specialty polymer sector, 4-Chlorobutyl Acetate functions as a chain-modifying agent, often utilized to introduce chlorinated side chains or acetate-protected functionalities during custom polymer backbone synthesis. By dosing into polymerization feed tanks, formulators gain precise control over chain branching, enhancing physical characteristics such as flexibility, chemical resistance, and surface reactivity. Production engineers routinely employ this material in tailor-making wire insulation, high-flex hose, and chemical-resistant films. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Industrial Solvent Blends and Cleaning Agents4-Chlorobutyl Acetate is valued among industrial formulators for blending into advanced solvent systems and heavy-duty cleaning agents, particularly those targeting removal of halogenated polymer residues or complex organic contaminants. Its moderate evaporation rate and solvency profile give process engineers flexibility to adjust overall cleaning power and residue control in automated spray, immersion, or ultrasonic cleaning lines, especially in electronics, metal finishing, and automotive assembly contexts. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
|
Competitive 4-Chlorobutyl Acetate prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: admin@sinochem-nanjing.com
Flexible payment, competitive price, premium service - Inquire now!
With decades rooted in chemical synthesis, we bring a practical perspective to the science and application of 4-chlorobutyl acetate. Factories demand consistency, and over the years, keeping batch-to-batch purity high has shaped how we run our reactors. The route we use for 4-chlorobutyl acetate, which most in the industry simply call 4-CBA, centers on precision and raw material transparency. Each step reflects hands-on problem-solving—from raw chlorination through acetylation, filtration, and then careful distillation.
We don't take shortcuts during production. Each run draws from what’s worked, and mistakes that didn’t, in past chemical campaigns. By designing our systems around process safety and tracing impurities at every stage, we avoid surprise downtime and minimize wasted time correcting off-spec output. We operate with a view that technical expertise and honest attention to plant-floor realities deliver better products in every drum shipped from our gates.
4-chlorobutyl acetate isn’t another bulk solvent. Our process yields a clear, pale liquid—free from the trace byproducts common in less disciplined plants. Controlling moisture and side reactions brings the residual acid content low and eliminates streaks of color that downstream users always fight to remove. The chemical’s moderate boiling point and good volatility distinguish it from heavier chlorinated ethers or higher-molecular acetate esters.
What stands out is how well 4-chlorobutyl acetate balances solvency and chemical stability. Its structure gives it enough polarity to dissolve specialty polymers, resins, or tough-to-handle organic intermediates, while the chlorine atom resists unwanted side reactions in multi-step synthesis. For formulators working with complex blends, this single property simplifies technical headaches and makes it easier to meet production schedules—especially in coatings and pharma intermediates, where batch timing runs tight and interruptions ripple down the line.
In our shop, we measure success by the numbers that matter: purity above 99 percent, water below 0.1 percent, acid value beneath 0.01 percent. Each of these is tracked as a process variable, not an afterthought. Staff running the columns and lines have seen how trace acids gum up packaging equipment or trigger rework batches. Our attention to heads and tails cuts down on these problems before they can affect customer manufacturing.
The finished product comes out as a clear liquid, nearly odorless, with a boiling range between 191 and 195 degrees Celsius. Compared with more volatile shorter-chain acetates, 4-CBA evaporates at a gradual pace, so solvent loss stays controlled during open mixing or blending. Viscosity is predictable, and flash point sits well above common safety thresholds, making warehouse and plant storage safer for handling crews.
There’s a saying among manufacturing engineers—don’t complicate things if you don’t have to. In the years we’ve been producing 4-chlorobutyl acetate, our customers return for a few simple reasons: reliability, fewer surprises in formulation, and support adapting to regulatory shifts. They run the compound through processes in synthetic resins, certain paint formulations, and as a working solvent in active pharmaceutical ingredient (API) synthesis.
Each setting brings its own quirks. Paints turn out brighter and smoother without haze when low-acid 4-CBA goes in. In resin lamination, master batch operators get fine control over viscosity and cure time. It outperforms typical ethyl or butyl acetate in formulations needing a slower evaporation rate or a solvent with higher resistance to hydrolytic breakdown. That consistency enables them to meet demanding technical specs without constant batch tweaking.
Looking at pharma applications, one trend stands out: process managers lean on 4-CBA as an auxiliary solvent where unwanted byproducts from lower-purity esters muck up yields. In these settings, product purity matters not just to a lab head, but to the bottom line of the company using it. Eliminating unplanned downtime or waste disposal issues adds up to a concrete dollar benefit few marketers outside a chemical plant truly appreciate.
Any chemical introduced into regulated industries faces a shifting landscape. As regulatory checkpoints tighten—REACH, TSCA, and equivalents—documentation and traceability rise in importance. Our in-house teams track not only what happens in our reactors, but also in the supply chains feeding our raw materials. In the last ten years, we’ve pushed hard for digital trace systems. Each batch number links back to logs—not just a piece of paper, but chromatograms and field audit data that inspectors want to see.
Efforts to stay ahead of regulatory changes aren’t always thanked, but a recall or shipment delay lands hard on a manufacturer’s doorstep. This drill has taught us the value of thorough record-keeping and real technical support—whether that means helping a customer revise a safety data sheet or adapt their process for a new purity threshold. That difference in hands-on involvement sets producers apart from traders who can’t answer where each lot truly comes from.
We work alongside customers testing every new project—comparing 4-CBA with alternative solvents. Where ethyl acetate or n-butyl acetate run too volatile for high-solids paint work, 4-chlorobutyl acetate fits as a more controlled evaporator. Its chlorine backbone resists breaking down as fast in the alkaline media found in engineered resin processing. This small detail impacts storage, shelf life, and product integrity further downstream.
In cleaning or extraction, 4-chlorobutyl acetate shows greater selectivity. Instead of flooding a system with solvent cocktails, chemists can fine-tune process parameters. Drop-in use doesn’t always work between solvents, but with 4-CBA’s nominal polarity, changes in retention, separation, or reaction rate allow more direct migration with minimal re-validation. That reduces downtime on legacy equipment—reducing cost of ownership, too.
Some competing solvents, like isopropyl acetate or heavier chlorinated hydrocarbons, either bring greater volatility and worker exposure or increase labeling complexity under hazardous substance guidelines. Our product avoids these headaches, which means less rework on transport documents and fewer training hours for new plant staff.
People sitting in research centers often miss what it takes to keep large chemical campaigns running smoothly. In our plant, we’ve had to resolve common challenges around phase separation, fouling, and feedstock quality. Our chemists work alongside operators to test and revise procedures. Years of hands-on troubleshooting—sometimes in night shifts when equipment or sensors go haywire—taught us what doesn’t get written in textbooks.
For example, our teams learned that real improvement in purity didn’t come from hardware upgrades alone. Better staff training on moisture control in glass-lined vessels gave us more progress than new distillation columns. Changing cleaning protocols between campaigns made a more repeatable product than software tweaks.
Many newer plants automate aggressively, but humans still spot the subtle signs—unusual foaming, shift in color, faint odors—that flag early trouble in 4-chlorobutyl acetate production. We build in scheduled manual checks for a reason. This tradition serves our customers because an operator who knows their line prevents more recalls than any instrument.
Shipping solvents involves risks, and over the years, we’ve faced most of them—drumming to destination, international regulatory hurdles, driver training, spill containment. Our on-site teams customize shipment types based on end-use, not generic packaging options. For 4-chlorobutyl acetate, safe drum or IBC loads can’t carry hidden water or headspace contaminants. We invest in inert gas blanketing and maintain a clean, temperature-controlled drum storage bay.
If a customer’s operation needs tank truck delivery rather than drums, we can set up dedicated routes, bypassing third-party operators who don’t know the technical side of the product. Critical shipment details—batch trace, fill levels, and compliance paperwork—are all handled by a crew that knows the impact of an error. These small details make a difference, especially under pressure from lean manufacturing schedules where delays can compound fast.
Continuous improvement sheds the buzzwords when lived on the plant floor. Over the years, customers have flagged outlying data in shipments, or caught subtle taste issues in food-safe resin systems. Instead of dismissing this feedback, we keep the doors open. Joint troubleshooting with customer engineers has caught upstream supplier drift, drum liner incompatibility, and new sources of runaway acidity before plant shutdowns happened.
We see our job as owning every liter from molecular synthesis to final end use. Direct technical service—not call centers or anonymous sales reps—means the chemists and operators who make 4-chlorobutyl acetate pick up the phone. Shared notes and laboratory support let our partners dial in their process, often raising total yield or cutting turnaround time far beyond the cost difference of premium raw material.
Responsible chemical production goes deeper than regulatory slogans. Our solvent plant operates with closed-loop recovery, water reuse, and solvent vapor containment right on the reactor line. We respond to new demands from the market—moving towards lower footprint chlorinating agents and minimizing total waste streams.
Solvent manufacturing draws attention for environmental impact, so our controls go beyond what auditors check. Scrubbers, effluent monitoring, and on-site waste management exist for a concrete reason: every kilogram of product that leaves the plant must have a measurable, trackable impact. We accept customer site audits, because credibility in environmental safety gets earned, not advertised.
Looking forward, 4-chlorobutyl acetate’s adaptability supports customer initiatives. Lower vapor emissions and reduced solvent losses put it in a better place than older, high-volatility alternatives. Customers who choose it gain in both compliance and process reliability.
We’ve crossed paths with plenty of third-party traders over the years, but they never bring the same commitment to production detail. As direct manufacturers, our involvement in 4-chlorobutyl acetate starts with raw material negotiation and ends with drums loaded on the dock. This hands-on span gives end-users a technical resource—beyond just a price sheet. If an issue arises, the answer never gets lost in translation.
Direct relationships also mean faster adaptation to customer-driven change. If an application needs a narrow impurity profile or an experimental blend in short order, we adjust our production schedule to run exclusive lots or tweak purification specs. Customers can see process records, talk to chemists, and gain confidence that new projects won’t derail because a broker’s supplier changed.
Chemistry always evolves. Over time, requirements for 4-chlorobutyl acetate may shift—towards more sustainable feedstocks, tighter purity, or integration into greener processes. Our team approaches these shifts as long-term partners to every customer. When we invest in research, it’s with a direct line to real-world bottlenecks. Our R&D group pilots changes weeks ahead of commercial batches, so end-users gain from advances the moment they reach production scale.
Value comes from sharing experience, not just from a finished commodity. The best upgrades to our process have come from working directly with technical teams across coatings, resin, pharma, and specialty chemical markets. Each improvement, whether in emissions controls or trace impurity monitoring, comes from dialogue on both sides of the table.
We know firsthand that manufacturing isn't just about numbers or technical stats—it comes down to reliability, service, and a willingness to stand behind each batch. 4-chlorobutyl acetate, made by people with real plant experience, reflects our approach: solve problems before they start, innovate only with reason, and treat every shipment as if our own operations depended on it. That commitment, rooted in practical manufacturing, defines the way we serve every customer.