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4-Chloro-3,5-Dinitrotoluene

    • Product Name 4-Chloro-3,5-Dinitrotoluene
    • Alias CDNT
    • Einecs 221-974-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    795671

    Iupac Name 1-chloro-2-methyl-4,6-dinitrobenzene
    Cas Number 121-25-1
    Molecular Formula C7H5ClN2O4
    Molecular Weight 216.58 g/mol
    Appearance Yellow crystalline solid
    Melting Point 95-97 °C
    Density 1.58 g/cm³
    Solubility In Water Insoluble
    Smiles Cc1c([N+](=O)[O-])cc(Cl)c([N+](=O)[O-])c1

    As an accredited 4-Chloro-3,5-Dinitrotoluene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 4-Chloro-3,5-Dinitrotoluene, 500g, supplied in a tightly sealed amber glass bottle with hazard labeling and tamper-evident cap.
    Shipping 4-Chloro-3,5-Dinitrotoluene is shipped as a hazardous material under strict regulations. It must be securely packaged in approved containers, clearly labeled, and accompanied by appropriate documentation. Transport is restricted to authorized carriers, with precautions to avoid heat, ignition sources, and physical damage. Emergency procedures must be established in case of spillage or exposure.
    Storage 4-Chloro-3,5-dinitrotoluene should be stored in a tightly sealed container, away from heat, sparks, and open flames. Keep it in a cool, dry, well-ventilated area, protected from direct sunlight and incompatible substances such as strong acids, bases, and oxidizing agents. Clearly label the container and ensure access is restricted to trained personnel following appropriate safety protocols.
    Application of 4-Chloro-3,5-Dinitrotoluene

    Applications of 4-Chloro-3,5-Dinitrotoluene in Industrial Manufacturing

    As an experienced producer of 4-Chloro-3,5-Dinitrotoluene, we supply this intermediate to key sectors requiring stringent quality, high purity, and consistent supply chain support. Below we outline its core industrial applications, precise integration into manufacturing, and compliance requirements in actual downstream markets.

    1. Synthesis of Explosives Intermediates

    Major nitroaromatic explosives manufacturers use 4-Chloro-3,5-Dinitrotoluene as a controlled precursor for advanced detonators and booster compositions. The material enters proprietary nitration and chlorination steps, where its high purity ensures consistent product yield and functional reliability under MIL-SPEC or similar precision demands. The tight control of impurities, isomer ratios, and residual chlorinated species is critical for security-regulated production streams. Product traceability, batch authentication, and transportation follow national and international regulations at each handling step.

    Industry compliance standards

    • U.S. ATF Explosives Regulations (27 CFR Part 555)
    • United Nations Recommendations on the Transport of Dangerous Goods (UN Model Regulations)
    • European Union REACH (EC No 1907/2006)
    • Defense Federal Acquisition Regulation Supplement (DFARS) Quality Clauses

    Typical usage ratio

    • Utilized at 15-30% w/w as part of charge fill, with ratio determined by desired performance sensitivity and environmental stability

    Downstream process integration

    • Introduced during initial charge blending; further processed through multistep nitration, reduction, and granulation under closed-system safety protocols

    Final product types

    • Primary and secondary explosive boosters
    • Detonator fuses
    • Military and civil blasting agents
    • Special formulations for oil and gas exploration charges

    2. Intermediate for Agrochemical Synthesis

    Agrochemical companies deploy this compound as a step in multi-stage synthesis of selective herbicides and fungicides. Careful management of isomeric purity, moisture, and trace metal content proves essential for downstream coupling and functionalization steps. Specific formulation ratios support active ingredient catalytic formation and purification efficiencies, while adhering to regulatory residue and emission limits in high-throughput manufacturing.

    Industry compliance standards

    • U.S. EPA Pesticide Registration (FIFRA)
    • FAO/WHO Specifications for Agricultural Pesticides
    • ISO 9001:2015 Quality Management (Production and Batch Release)
    • EU Regulation (EC) No 1107/2009 concerning Plant Protection Products

    Typical usage ratio

    • Feeds between 10-22% of process material in condensation and coupling stages, adjusted for molecular yield and end-product regulatory thresholds

    Downstream process integration

    • Charged at the diazotization or chlorination branch before subsequent heterocyclic formation; strict in-line QC on chlorinated dinitrotoluene carryover

    Final product types

    • Chloro-nitro aromatic herbicide actives
    • Broad spectrum cereal fungicide intermediates
    • Preparatory scaffolds for plant growth regulators
    • Bulk synthesis for pre-formulation crude

    3. Dye and Pigment Manufacturing

    Colorant manufacturers rely on this intermediate for azo dye and nitro pigment generation, where controlled substitution and subsequent coupling yield high-performance textile, leather, or ink pigments. Specific downstream steps demand minimal byproduct formation and controlled particle morphology. Feedstock uniformity enables batch reproducibility in both small-lot specialties and large-lot production, reducing filtration and purification burdens throughout the dye manufacture cycle.

    Industry compliance standards

    • OEKO-TEX Standard 100 (Textile Chemicals Restrictions)
    • EU REACH Restriction on Allergens and Hazardous Impurities
    • ISO 14001 (Environmental Controls for Dye Synthesis)
    • ASTM D4287 (Standard Practice for Testing Colorants)

    Typical usage ratio

    • Typically incorporated at 18-35% by mass within the core arylation or diazo coupling reactor, depending on final chromophore intensity and substrate compatibility

    Downstream process integration

    • Charged as the initial aromatic substrate in nitrate dye reactors; purified before acid or alkali saltification and spray drying

    Final product types

    • Nitro-based azo textile dyes
    • High-stability yellow and orange pigments for plastics and inks
    • Solvent dyes for leather finishing
    • Color base intermediates for digital inkjet applications

    4. Pharmaceutical API Synthesis (Non-Final Drug, Precursors Only)

    Pharmaceutical API producers utilize this chemical as a building block for niche active pharmaceutical ingredients, especially in the synthesis of intermediates for antimicrobial and antineoplastic research. Purity grade, identification of 2,4- and 3,5-isomers, and trace impurity quantification require validation by compendial standards. The compound is never presented in end-use formulations, but supports controlled reduction, halogen exchange, and derivatization processes prior to finished API salting and crystallization.

    Industry compliance standards

    • Current Good Manufacturing Practices (ICH Q7, US FDA 21 CFR Part 210/211)
    • European Pharmacopoeia Monographs (where applicable for intermediate validation)
    • Health Canada API Import/Export Controls
    • USP General Chapter <797> (Contamination Control for Intermediates)

    Typical usage ratio

    • Ranges from 8-16% by batch mass as a single-position halogen donor or nitro block in the stepwise API precursor build; ratio tailored according to final impurity profile and regulatory expectation

    Downstream process integration

    • Directly charged in early-stage aromatic substitution; processed through multi-step reduction/hydrolysis and subsequent ring closure under GMP systems

    Final product types

    • Non-clinical antibiotic intermediate batches
    • Antitumor candidate API scaffolds
    • R&D scale specialty chemical libraries
    • Intermediates for veterinary compound research
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    Certification & Compliance
    More Introduction

    Introducing 4-Chloro-3,5-Dinitrotoluene: A Practical Perspective from the Manufacturer

    Real-World Uses of 4-Chloro-3,5-Dinitrotoluene

    4-Chloro-3,5-Dinitrotoluene has earned its place in the manufacturing sector for a simple reason—it works where high-performance intermediates are needed for more demanding chemical syntheses. Years of direct involvement in the synthesis, handling, and delivery of this compound taught us just how much experience and discipline matter. This isn’t just another base material you throw in a mix for marginal gains. It brings stability and reliability in processes where you often only get one shot to get things right, especially in the production of high-value dyes, pigments, and certain pharmaceuticals.

    Laboratories and production floors come to rely on it as a building block for specific chlorinated nitroaromatic derivatives. Our colleagues in the field have told us time and again that half-hearted alternatives can lead to side reactions and wasted effort. 4-Chloro-3,5-Dinitrotoluene doesn’t just participate in chemistry; it shapes it, steering reactions toward the products customers actually want at a scale that makes sense for industry.

    Our Consistency and Approach

    Every ton that leaves our plant looks the same for a reason—consistency in synthesis and strict traceability of each batch. Over years, we noticed the effects of variability: inconsistent melting points, off-colors, or residual moisture will upend batch processes further down the chain. We don’t push unchecked material out the door—no producer with integrity does. At a practical level, this means granular attention to feedstock purity and constant monitoring of crystallization conditions, backed by established procedures and people who know that running through the motions leads nowhere fast.

    Not every operator follows the same formula, so we engineered our output to suit what actually happens in plants, not on paper. Slightly refining particle size distribution has cut down on dust during transfer, reducing hazards for everyone involved. Tightening upper-bounds on moisture content ensures the powder flows and dissolves as expected, so our downstream partners don’t wrestle with clumping or inconsistent reactivity. Regular customers appreciate these details more than polished brochures.

    Practical Specifications That Matter

    Chemicals are more than formulas and CAS numbers—they’re judged on how they behave during handling, storage, and use. For 4-Chloro-3,5-Dinitrotoluene, melting point and purity drive almost every quality discussion. Realistic expectations, not theoretical targets, set the tone: customers demand a product that won’t cause headaches on their lines, so we routinely supply purity at ≥99% by HPLC, which all but eliminates uncertainty in subsequent syntheses. Crystallization is controlled to avoid contamination and avoid the risk of unexpected reactivity.

    Moisture is monitored by Karl Fischer titration, and we keep it low—well below levels where agglomeration becomes a problem. Bulk density doesn’t vary wildly from drum to drum, so dosing systems perform as models predict. We see this as basic respect for the challenges other manufacturers face; real problems aren’t solved with abstract promises, but with data and reliability.

    What Sets 4-Chloro-3,5-Dinitrotoluene Apart

    Manufacturers often ask, “What makes this grade different from others like 2,4-dinitrotoluene or plain dinitrotoluene?” It’s a fair question. From our experience, the unique arrangement of nitro and chloro groups in this molecule changes everything about how it reacts. Many classic dinitrotoluene derivatives lack the chlorinated structure, limiting their use in syntheses targeting chlorinated intermediates. That difference shows up in reaction yields, selectivity, and even color stability in finished products. Downline partners in dye and pigment manufacturing value that difference because it translates to fewer purification headaches and higher-value outputs.

    Unchlorinated analogs sometimes seem easier to source, but anyone who’s run high-throughput nitration lines sees the limits quickly: more sulfur contaminants, higher sensitivity to trace metals, and a broader side product profile. 4-Chloro-3,5-Dinitrotoluene narrows the variable field, delivering repeatable, focused reactivity—not always flashy, but consistently valuable in the right hands.

    Lessons Learned from On-the-Ground Operations

    Our plant runs have seen everything: blocked filters, sticky product flows, even the odd cloud of dust that sets off alarms. We didn’t get it right by chance; it came from fixing what went wrong. Tuning the final drying step and temperature controls meant fewer product losses and less environmental discharge. Installing additional dust collection equipment gave operators safer working conditions and cleaner drum fills. These adjustments didn’t come from textbooks; they came from conversations with the teams running the show.

    Customers have approached us with technical issues of their own—tan coloring in final products, unexpected byproducts, or stubborn clumping in feeders. These problems circled back to raw material consistency or packaging issues. We worked together to develop solutions, including antistatic liners and sealed pack-offs for high-humidity environments. Sharing data with downstream labs led us to adjust impurity profiles, so our partners spent less time in purification and more time making valuable intermediates.

    Long-Term Product Reliability

    It’s one thing to sell a compound that passes today’s checks, another to deliver it with predictable performance for years. Our team tracks batch data and product returns because this process surfaces the quiet trends that matter—a subtle uptick in off-spec, a gradual change in odor, things that spreadsheets alone won’t explain. Addressing them early on, before a complaint hits, saves time and builds genuine trust.

    Reliable sourcing allows partners to plan quarterly and annual production, allocate budgets, and commit to their clients. Gaps in supply don’t just hurt the relationship; they can halt entire synthesis chains and sideline teams. We respect how much depends on our ability to ship on time and in grade. Our logistics approach blends straightforward packaging—leveraging UN-rated drums and standardized labeling—with flexible shipment planning, so our material arrives when production is ready, not before or after. Our regulars know to expect what they ordered, every time.

    The Human Element: Health, Safety, and the Environment

    Each run in a chemical plant exposes teams to potential risks, and nothing matters more than sending people home safe each night. The nitroaromatic class isn’t known for gentle handling. Early on, we learned that protecting skin and airways from dusts and vapors means installing better ventilation, providing tested PPE, and training every operator until the response to a spill or exposure is second nature.

    Environmentally, our focus shifted as we saw the impact of even small process changes. We invested in process water treatment and emissions controls, drastically reducing nitroaromatic discharge into air and drains. Waste streams are tracked and minimized; it isn’t just for the permits or standards, but because experience teaches how easily shortcuts can cause bigger problems down the line. Recycling process solvents and capturing heat cuts costs, but more importantly, it trims our footprint without extra paperwork or claims. The health of local communities and surrounding ecosystems depends on vigilance—and on being straightforward about mistakes, not hiding them.

    Partnership, Not Just Supplier Relationships

    Customers don’t come to us looking for the lowest headline price or grand marketing. They come with technical questions: “Will this new batch affect our reaction route? Can your team help us trace batch consistency if a process goes off-spec? Can we get shipment quantities that fit with our plant’s storage?” Real partnerships start with listening. When teams on both ends of the supply chain talk openly, frustrating problems get worked out faster—sometimes even before they become critical.

    We often field requests for modifications: smaller packaging for lab-scale evaluations, lot-specific certificates of analysis, or adjusted impurity controls for customers pursuing critical pharmaceutical intermediates. Fulfilling these requests means understanding the reasoning behind them, not just checking a box. We’ve assembled a technical support group, staffed by people with years on the shop floor and in the lab, who spend more time on video calls with our partners than in meetings about future targets. They solve real-world issues, not hypothetical ones.

    These close connections fuel our improvements too. More than once, feedback from someone handling the product halfway around the world led to a process tweak here—reducing caking, improving solution rates, or adjusting packaging for easier handling in a different climate. As much as specifications define a chemical, the relationships we build define the business.

    Regulatory and Market Pressures

    Regulatory frameworks in the specialty chemicals arena grow tighter each year—for good reason. We stay alert to major changes in REACH, TSCA, and local registration rules because compliance keeps everyone in business. Strict attention to SDS documentation, batch-specific record keeping, and routine audits from authorities doesn’t get in the way of production; instead, it reassures both us and the customer that the supply chain is robust and traceable.

    Market demand can shift with little notice, especially when new pharmaceutical or pigment applications emerge. We’ve ridden the wave of increased demand due to a single patent approval and weathered the slowdowns that come from overcapacity in related industries. Adaptability is essential. Investing in scalable reactors and intermediate storage lets us meet surges without overextending. Open discussions with customers about lead times and forecasts help tamp down unhelpful speculation or panic-buying. Communicating with clarity—before problems surface—wins more respect than keeping quiet and hoping for the best.

    Quality Built by Experience

    Every kilogram of 4-Chloro-3,5-Dinitrotoluene carries the history of trials, adaptations, and small victories. Years in the trenches teach you to spot issues before they take root: a subtle shift in crystal color, unexpected clumping in a fresh batch, or an off-odor that hints at moisture. No process is set-and-forget. Every technician, operator, and lab analyst adds their insight, making feedback a regular part of production.

    The product’s role as a mature intermediate in pigment and pharmaceutical lines forces us to maintain strict quality standards, not only to avoid rework, but to keep customers’ processes humming along without interruption. Trust, in this industry, is built batch by batch and broken even faster by inconsistency or secrecy.

    Collaboration and Looking Ahead

    The specialty chemical world grows more interdependent each year. Staying competitive doesn’t just mean scaling up reactors or improving yields, but learning from every complaint, question, and unexpected result. Our technical team spends time in customer plants, not just at the lab bench, watching actual operators handle drums and charge reactors. Their insights feed right back into our manufacturing workflow.

    We continue to invest in people, not just equipment, trusting that solving today’s practical problems will open up new applications and specialty markets. Whether helping a partner refine their dye synthesis or customizing packaging for a customer in a damp coastal region, our real goal remains the same—making 4-Chloro-3,5-Dinitrotoluene safer, more reliable, and better suited to the realities of the industry. Experience, open communication, and a willingness to address issues head-on drive lasting success.

    Summary

    For anyone in the market for 4-Chloro-3,5-Dinitrotoluene, the number printed on a certificate only tells part of the story. What matters most, year after year, is that each drum and every ton represents a commitment to quality, consistency, and honesty. Customers demand more than chemistry—they expect support, technical insight, clear communication, and the willingness to get things right the first time, and every time after that. From our side, those are the standards we live by, forged by daily experience and a history of challenges overcome together.