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4-Chloro-1,3-Benzenedithiol

    • Product Name 4-Chloro-1,3-Benzenedithiol
    • Alias 4-Chloro-1,3-benzenedithiol
    • Einecs 696-019-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    177845

    Chemical Name 4-Chloro-1,3-Benzenedithiol
    Molecular Formula C6H5ClS2
    Molecular Weight 176.69 g/mol
    Cas Number 16752-77-1
    Appearance Yellow to brown solid
    Melting Point 71-75°C
    Density 1.53 g/cm³ (approximate, at 20°C)
    Solubility Slightly soluble in water; soluble in organic solvents
    Smiles C1=C(C=C(C=C1S)Cl)S
    Pubchem Cid 23408772

    As an accredited 4-Chloro-1,3-Benzenedithiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, tightly sealed, labeled "4-Chloro-1,3-Benzenedithiol, 25g," with hazard symbols and safety, storage instructions.
    Shipping 4-Chloro-1,3-Benzenedithiol is shipped in tightly sealed containers, protected from light and moisture. It should be packaged according to all applicable regulations for hazardous chemicals, ensuring proper labeling and documentation. Shipping generally occurs under ambient temperature, with precautions to avoid leaks or spills during transit. Handle with appropriate safety measures.
    Storage 4-Chloro-1,3-Benzenedithiol should be stored in a tightly sealed container, away from light, moisture, and incompatible substances such as oxidizing agents. Store it in a cool, well-ventilated area, ideally in a flammable chemicals storage cabinet. Ensure the container is clearly labeled and kept away from sources of ignition and direct sunlight. Use appropriate personal protective equipment when handling.
    Application of 4-Chloro-1,3-Benzenedithiol

    Applications of 4-Chloro-1,3-Benzenedithiol in Industrial Manufacturing

    As the manufacturer of 4-chloro-1,3-benzenedithiol, we supply this specialty intermediate in strict alignment with downstream industry requirements. Our material features high purity and controlled reaction profiles to meet advanced technical standards for specialized chemical manufacturing. Below are the principal downstream application scenarios using our product, with detailed compliance, process, formulation, and end product information for B2B industry professionals.

    1. Advanced Polymer Crosslinking Agents in High-Performance Materials

    Manufacturers of specialty polymers and engineering plastics apply 4-chloro-1,3-benzenedithiol as a functional crosslinker for improving chemical and thermal resistance. Its two thiol groups and reactive chlorine allow for covalent integration into polymer backbones, commonly in halogen-resistant elastomers or polyimide systems used in harsh environments. The material fits within the chemical modification step prior to polymer extrusion or molding. Processing requires careful handling to achieve uniform crosslink density and maintain mechanical properties of the final plastic part.

    Industry compliance standards

    • ISO 9001:2015 Quality Management System for Specialty Chemicals
    • REACH Regulation (EC) No 1907/2006 (applicable to importers and users in the EU)
    • RoHS Directive (2011/65/EU) for electronic plastics (as applicable to final uses)

    Typical usage ratio

    • Crosslinker loading ranges from 0.1% to 1.5% by weight of total monomer mass, depending on target crosslink density and desired final performance.

    Downstream process integration

    • Added during the polymerization or compounding stage, often under inert atmosphere, prior to extrusion, molding, or vulcanization steps.

    Final product types

    • High-thermal-resistance elastomers for electrical insulation
    • Halogenated engineering plastics for aerospace and automotive underhood applications
    • Crosslinked polyimide components for semiconductor substrates

    2. Synthesis of Ligands for Metal Catalysts in Pharmaceutical Intermediates

    The compound serves as a precursor for chelating ligands used to stabilize transition metal catalysts. In pharmaceutical synthesis, these catalyst systems facilitate key C–C and C–S bond-forming reactions at scale. The dithiol functional groups anchor to metal ions for use in homogeneous catalysis, with rigorous QC on purity and trace metal content. Downstream users customize ligand structure by nucleophilic substitution at the 4-chloro site, optimizing catalyst performance for target reactions such as Suzuki or Heck coupling.

    Industry compliance standards

    • GMP ICH Q7 guidelines for starting materials (as adopted for API synthesis)
    • USP-NF for catalyst impurity limits (as relevant for APIs)
    • 21 CFR Part 211 (US cGMP for finished pharmaceuticals)

    Typical usage ratio

    • Ligand precursor loading typically ranges from 0.8 to 3.0 mol% relative to the metal center in catalyst synthesis, adjustable based on catalytic turnover and substrate type.

    Downstream process integration

    • Functionalized at the 4-chloro moiety via nucleophilic substitution, then complexed with transition metal salts as catalyst preparation step for integration into pharmaceutical batch reactors.

    Final product types

    • Palladium or platinum catalyst complexes for pharmaceutical fine chemical manufacturing
    • Active pharmaceutical ingredients (APIs) manufactured by cross-coupling or thiolation reactions
    • Intermediates for small molecule drug synthesis

    3. Corrosion-Resistant Coatings for Electronics and Engineering Components

    Producers of specialty coatings use the dithiol compound as a building block for thiol-based surface treatment agents and anti-corrosive resin formulations. Its structure promotes strong adhesion to metal surfaces and dense crosslinked networks, resisting degradation in aggressive chemical or marine environments. It enters the downstream process as part of coatings formulation or as a reactive additive in thiol-ene chemistry for UV-curing applications.

    Industry compliance standards

    • ISO 12944 (Corrosion Protection of Steel Structures by Protective Paint Systems)
    • IEC 61086 for coating materials in electronics
    • ASTM D1654 (Standard Test Method for Evaluation of Painted or Coated Specimens Subjected to Corrosive Environments)

    Typical usage ratio

    • Usage typically falls between 0.5% and 2.5% by total resin mass, with higher loads for marine coatings or high-salinity conditions.

    Downstream process integration

    • Integrated at the resin pre-polymerization stage, or post-added as a curing accelerator in UV/epoxy systems for electrodeposition or brush application of coatings.

    Final product types

    • Anti-corrosive coatings for PCBs and industrial electronics
    • Protective paints for marine and offshore steel infrastructure
    • Surface primers for valve bodies, pump housings, and chemical reactors

    4. Sulfur-Modified Vulcanization in High-Durability Rubber Goods

    Tire and sealing component manufacturers utilize the dithiol compound as a reactive modifier in sulfur cure systems. Its thiol structure enables shorter vulcanization times and enhanced crosslink stability. The additive supports stabilization of physical properties under thermal cycling and oxidative stress, particularly in high-performance rubber compounds for automotive and industrial use. Its role is critical within the compounding and mixing stage before press curing or extrusion.

    Industry compliance standards

    • ASTM D2000 (Rubber Products in Automotive Applications)
    • ISO 14001 for environmental compliance in rubber manufacturing
    • REACH Annex XVII (Restrictions on hazardous substances in rubber components)

    Typical usage ratio

    • Incorporated at 0.05% to 0.8% by total rubber compound weight, adjusted for rubber type and required cure characteristics.

    Downstream process integration

    • Added during the masterbatch phase of rubber formulation, prior to the crosslinking cure at elevated temperature and pressure.

    Final product types

    • Radial automotive tires for commercial vehicles
    • Resilient sealing gaskets and O-rings for machinery
    • Performance rubber hoses for chemical transfer

    5. Molecular Linkers in Organic Electronic Materials

    Manufacturers of organic semiconductors and photonic materials use the dithiol as a molecular linker to build conjugated systems for electronic and optoelectronic devices. Its two functional thiol groups enable construction of self-assembled monolayers and interface anchoring on gold or silver electrodes. The compound integrates into solution-phase organic synthesis steps, followed by purification tailored for high-purity device applications, emphasizing control over residual contaminants and electrical performance.

    Industry compliance standards

    • IPC-6012 (Qualification and Performance Specification for Rigid Printed Boards)
    • ISO/IEC 17025 for laboratory QC of electronic materials
    • REACH compliance for restricted impurities in electronics

    Typical usage ratio

    • Dose in surface modification typically 1–10 nmol/cm², or as 0.1–1% in bulk organic layers by weight, with adjustment for device dimensions and target film conductivity.

    Downstream process integration

    • Functionalization of electrode surfaces via immersion coating; copolymerization or blending in photoresist resins or conductive inks during device fabrication workflows.

    Final product types

    • Organic field-effect transistors (OFETs)
    • Photovoltaic cells using organic thin films
    • Flexible and transparent electronic displays
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    Certification & Compliance
    More Introduction

    4-Chloro-1,3-Benzenedithiol: Practical Insights From The Manufacturing Floor

    Direct Experience With 4-Chloro-1,3-Benzenedithiol Production

    Walking into the synthesis block, the sharp, recognizably sulfurous hint immediately marks a batch of 4-Chloro-1,3-benzenedithiol coming through the reactors. This molecule, produced with care in our facility, not only marks a critical link in specialty chemical supply chains but also demonstrates the intricacies that differentiate true chemical manufacturing from packaging or trading operations. Here, we track batches from raw input to finished product, understanding every nuance—each step validated by our own hands and eyes.

    Form, Purity, and What Real Manufacturing Means for Quality

    Unlike resellers, we start from primary materials and set our standards through hands-on synthesis, not just test certificates. For 4-Chloro-1,3-benzenedithiol, detailed purity measurement isn’t a footnote. We consistently achieve purity levels above 98%, with most lots reaching or surpassing 99%. Our analytical chemists verify this result using gas chromatography and NMR, comparing each lot against tight internal benchmarks we have established through years of production. The pale yellow to off-white crystalline solid is the direct result of a tightly controlled process, not mere repackaging. Small bits of color or trace solvent can tell us a lot during production, so every batch runs through a careful visual and instrumental inspection before being cleared for drumming or custom packaging.

    Traceability You Can Track Back to the Starting Flask

    People often ask what makes a direct manufacturer’s product different from what appears, at first glance, to be the same chemical from a distributor. It’s about the chain of control. For us, every kilogram of 4-Chloro-1,3-benzenedithiol is linked to a raw batch, a dedicated vessel, a specific processing timeline. We log environmental conditions and use a proprietary purification filtration designed to minimize moisture retention and impurity carryover. This is not just for compliance checks—it’s because experience has shown us that stray moisture not only degrades stability but can wreck the reactivity in downstream coupling reactions where this compound often finds a role.

    Model and Batch Consistency: What Sets Manufactured Material Apart

    Manufacturers hear from end users when something changes: a shift in melting point, a slight dulling in color, or any residue that interferes with the next step in synthesis. Over time, we have honed a consistent batch profile, using a robust process model developed in our own lab. Unlike generic, off-the-shelf lots that change hands across continents, our 4-Chloro-1,3-benzenedithiol bears a signature—batch-to-batch repeatability. Chemists rely on this product for sensitive cross-coupling reactions, macrocycle construction, or as a pivotal ligand in coordination chemistry. Problems can set in when the compound drifts out of spec. Distributors sometimes struggle to explain such changes, but as direct manufacturers, we recognize these signals fast, right at the synthesis step, and correct them before product leaves the plant.

    Why Application Demands Matter, and Where This Product Excels

    In the world of fine chemical synthesis, details determine success or failure. Our customers, often research and advanced development labs, need their 4-Chloro-1,3-benzenedithiol not just to “meet spec” but to succeed in applications as diverse as organic electronics, sulfur-containing macrocycles, or high-performance polymer additives. One customer told us one off-note in purity caused unexpected yellowing in their polymer. Another ran into trouble with poorly washed batches clogging processing lines. These are not abstract risks. Many don’t realize that minor variations in impurity profiles—a trace bit of excess 1,3-benzenedithiol or a hint of residual solvent—can derail an entire campaign of experiments.

    Having open lines of communication with our users, we prioritize not just standard purity but profiles suited to downstream reactivity. We document each batch’s impurity fingerprint from HPLC and NMR. That gives researchers and process chemists real confidence—not just a piece of paper, but clear data they can review and correlate with their results. Our technical support stems from the chemists who actually ran the synthesis, not an abstract helpdesk or resold literature page.

    Comparing to Other Dithiols: The Influence of the Chloro Substituent

    Some ask whether they can substitute another benzenedithiol for 4-chloro-1,3-benzenedithiol, perhaps to shave costs or source from generic catalogs. Our experience points to why that’s rarely a straightforward swap. The 4-chloro substituent is not just cosmetic. In radical polymerizations, coupling reactions, and controlled molecular assemblies, this modification tunes electron density and reactivity across the aromatic core. End users have reported significant differences in reactivity and yield when switching from the standard benzenedithiol to our chlorinated variant. Our in-house research found improved selectivity for some metal-coordination complexes, with less background reactivity. Certain electronic materials use this product precisely because the chloro-substituted form blocks unwanted side reactions, a small but important difference that can introduce greater performance consistency in advanced devices.

    Safety, Stability, and Practical Handling Considerations

    At the plant, we never take shortcuts with hazardous materials. 4-Chloro-1,3-benzenedithiol brings its own challenges, including a distinct odor and potential to form volatile sulfur compounds under heat or light. We’ve seen what happens if packaging seals are compromised—free-flowing odor, product degradation, and, at worst, regulatory questions. Tight secondary containment, sealed drums, and humidity-controlled storage keep these risks in check. Direct manufacturing gives us the insight to suggest best practice handling protocols, since we’ve solved these issues ourselves (not just copied from upstream). We built our packaging protocols through internal trials, learning firsthand where risks emerge during both storage and worldwide shipping.

    Regulatory and Supply Chain Realities

    As global regulatory expectations rise, our firsthand knowledge meets the moment. Most compliance-focused customers know the challenge: They face tighter import rules, scrutiny on chemical identity and batch integrity, and increasing demands for full supply chain traceability. With manufactured batches, we document each stage, from raw entry and synthesis to impurity tracking and full lot release. This documentation answers real questions on request—how was the product made, what was the environmental compliance record, what checks were in place against cross-contamination? These are not fill-in-the-blank forms but production records made for ourselves and our customers in mind.

    Supply chain headaches rarely stop at purchasing. One customer needed guaranteed continuity for three years. We used our archived batch records and in-house reference stocks to demonstrate true continuity across hundreds of kilograms—a promise resellers simply can’t make when product moves through long, indirect channels. As volatility grows in chemical feedstocks, direct manufacturers offer more reliable forecasting. We control and buffer our inputs, not just relay orders.

    Supporting Emerging Applications and Custom Integrations

    Field experience shows that innovation doesn’t stand still. A surge of interest in sulfur-based ligands for coordination polymers led to new inquiries just last year. We worked alongside two major research teams to adjust our drying protocols, reducing a trace impurity that interfered with certain catalytic cycles. Because we run the synthesis, we can—within process safety margins—tweak and improve, feeding those improvements right back into the product before it ever reaches another lab.

    This kind of responsiveness doesn’t happen through anonymous global supply chains or third-party “spec matching.” It takes real-time feedback: a phone call from a user, an internal QC review, a shift in how batches are washed or dried. Feedback from real users guides us more than marketing ideas. Innovation in this space comes from practical problem-solving, not fancy packaging or brochure promises.

    Experience in Environmental Responsibility and Waste Minimization

    Running a full-scale plant, waste streams aren’t a theoretical concern. Every synthesis batch yields both product and byproducts—spent reagents, mother liquors, wash solvents. Regulations now demand answers on waste minimization and safe handling, but our practices grew out of years of cleanup, not just compliance. We pushed towards solvent recycling, in-line monitoring, and minimal exposure handling to reduce not just costs, but risk to both staff and the local environment. Switching filtration media last year, for instance, cut our aqueous effluent sulfur content by a measurable margin, responding directly to new internal goals for sustainability. These details rarely appear on reseller MSDS sheets but represent real changes with meaningful results.

    Facing Supply Crisis and Raw Material Volatility, With Adaptability

    Chemicals like 4-Chloro-1,3-benzenedithiol don’t exist in a vacuum. Feedstock prices, especially chlorinated aromatics and sulfur donors, fluctuate. Traders and resellers feel these as price shocks or limited allocations, but as the site that runs the reactors, we manage the impact directly. Keeping alternative supply routes open, dual-sourcing critical intermediates, and holding buffer stock built from direct production all make a difference in being able to deliver reliably even during market disruptions. Over the past decade, spot shortages in key feedstocks put traders on the back foot. In our experience, end users—academic labs, electronics developers, polymer chemists—have come to us for stable, forecastable timelines, especially during periods of high raw material volatility.

    What ‘Direct From Manufacturer’ Delivers for You

    From this side of the process, the gap between direct manufacturing and indirect resale shows up in every container that leaves our site. Each batch’s journey traces through our alarms, logs, and people, not just transit slips. When a technical issue crops up—a color change, an unexpected result, a special request for pre-dried or smaller packs—responses and solutions come from firsthand knowledge. Our chemists and process engineers have seen what causes those surprises because they’ve made and tested the product themselves.

    For research and high-end production, the difference in starting material quality changes more than just the input cost. Using truly controlled 4-Chloro-1,3-benzenedithiol cuts batch failures, improves yields, and lets users trust what happens in their reactors matches what’s listed on the label. Our decision-making comes from practical, in-plant troubleshooting—whether it’s optimizing our purification process to minimize dithiol impurities for a photochemical process or blocking out any possible contamination by switching to dedicated glassware and glovebox handling for sensitive batches.

    Feedback, Continuous Improvement, and Partnership—From Our Perspective

    Daily work in chemical manufacturing revolves around constant improvement: a cycle driven by both internal observations and customer calls. 4-Chloro-1,3-benzenedithiol isn’t just a catalog entry here—it’s a product we live with, aware of where things can go sideways and how to preempt those issues. When a researcher calls about a process irregularity, we check our own synthesis logs, not just stock numbers. That real connection to the chemistry guarantees more meaningful troubleshooting, with solutions grounded in realistic batch experience.

    Instead of relying solely on QC testing at the end of production, our chemists pair in-process data with material-driven improvements, taking feedback from users and translating that insight into improved batches. This loop of feedback, adjustment, and enhanced synthesis marks a real difference with what users see from simple repackagers, where product is already out of their hands.

    Outlook: Supporting Advances With Reliable Materials

    Specialty chemicals like 4-Chloro-1,3-benzenedithiol find their way into the heart of new research, electronics, and advanced materials. Their reliability, reactivity, and quality start at the manufacturing floor. As new applications develop and regulatory, environmental, and supply chain challenges rise, our pledge to direct, controlled manufacturing gives users a foundation for confident experimentation and production. From firsthand observation, material performance begins with the details of process knowledge, tight analytical control, and an organizational habit of rooting improvements in actual batch experience.

    By focusing on these principles, we support both our local chemical community and a growing network of researchers and technologists worldwide. Trust in 4-Chloro-1,3-benzenedithiol’s quality reflects trust in the care and commitment behind each batch—a responsibility we meet daily.