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4-Benzoylbiphenyl

    • Product Name 4-Benzoylbiphenyl
    • Alias 4-Benzoyl-1,1'-biphenyl
    • Einecs 208-047-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    890913

    Chemical Name 4-Benzoylbiphenyl
    Cas Number 2128-93-0
    Molecular Formula C19H14O
    Molar Mass 258.32 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 125-129 °C
    Boiling Point 464.2 °C at 760 mmHg
    Density 1.14 g/cm3
    Solubility In Water Insoluble
    Synonyms p-Benzoylbiphenyl, 4-Phenylbenzophenone
    Smiles C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)C3=CC=CC=C3
    Inchi InChI=1S/C19H14O/c20-19(15-9-5-2-10-16-15)18-14-8-7-13-17(18)12-6-1-3-11-13/h1-14H
    Refractive Index 1.663
    Storage Conditions Store at room temperature, keep container tightly closed

    As an accredited 4-Benzoylbiphenyl factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 25g 4-Benzoylbiphenyl comes in an amber glass bottle with a secure cap and detailed hazard and product labeling.
    Shipping 4-Benzoylbiphenyl is shipped in compliance with relevant regulations, securely packaged in airtight, chemical-resistant containers to prevent leaks or contamination. Proper labeling, including hazard identification, is ensured. The shipment is protected from direct sunlight, heat, and moisture, and accompanied by a Safety Data Sheet (SDS) for safe transport and handling.
    Storage 4-Benzoylbiphenyl should be stored in a tightly sealed container, protected from light and moisture, and kept in a cool, dry, and well-ventilated area. Avoid exposure to heat, open flames, and incompatible materials such as strong oxidizing agents. Store it in a designated chemical storage area, away from food and incompatible substances, and ensure appropriate labeling and handling procedures are followed.
    Application of 4-Benzoylbiphenyl

    Applications of 4-Benzoylbiphenyl in Industrial Manufacturing

    As a direct manufacturer of 4-Benzoylbiphenyl, we support multiple advanced industrial sectors through consistent supply and technical collaboration. Our focus remains on proven application tracks, ensuring compliance, reproducibility, and integration efficiency in every batch.

    1. Liquid Crystal Intermediate for Display Technology

    4-Benzoylbiphenyl serves as a high-purity intermediate for synthesizing advanced liquid crystal materials. Its rigid molecular structure enhances mesogenic properties, directly impacting phase transition temperatures and alignment in liquid crystal mixtures. Leading panel manufacturers rely on its consistent quality to achieve precise electro-optical performance in TFT-LCDs and OLEDs for industrial and consumer displays.

    Industry compliance standards

    • IEC 61747 series for liquid crystal display devices
    • RoHS Directive (2011/65/EU) for restricted substances
    • REACH Regulation (EC) No 1907/2006
    • ISO 9001:2015 for quality management

    Typical usage ratio

    • 5–20% by weight in the final mesogen mixture
    • Ratio adjusted based on desired birefringence and dielectric properties
    • Purity must exceed 99.5% to avoid display defects
    • Batch homogenization strictly controlled during large-scale blending

    Downstream process integration

    • Enters as a key reactant during liquid crystal mixture formulation
    • Dissolved and homogenized with other mesogens under inert atmosphere
    • Final mixture filtered and vacuum-distilled to remove contaminants
    • Directly filled into panel production lines under cleanroom standards

    Final product types

    • TFT-LCD modules for industrial automation displays
    • OLED screens for high-resolution monitors
    • Medical-grade diagnostic display panels
    • Ruggedized screens for automotive dashboards

    2. Photoinitiator Synthesis for UV-Curing Coatings

    Manufacturers use 4-Benzoylbiphenyl as a precursor in the synthesis of photoinitiators for UV-curable resins. Its conjugated aromatic structure optimizes UV absorption at specific wavelengths, increasing curing speed and depth control in industrial and packaging coatings. The raw material’s consistency ensures batch reproducibility in photoinitiator performance.

    Industry compliance standards

    • ISO 9001:2015 for process control
    • FDA 21 CFR 175.300 for coatings with food contact
    • EU Regulation (EC) No 10/2011 for plastics in food packaging
    • ANSI/ASTM D7767 for UV-curable formulations

    Typical usage ratio

    • Used at 10–30% of total photoinitiator precursor load
    • Downstream initiator added at 1–5% in final resin mix
    • Ratio depends on film thickness and substrate type
    • Particle size distribution and dispersibility optimized for curing uniformity

    Downstream process integration

    • Used during photoinitiator synthesis in controlled batch reactors
    • Reacted with acylating or alkylating agents to form functionalized initiators
    • Finished initiator incorporated directly in UV-curable resin blending
    • Quality tested for absorbance profile using UV-VIS spectrometry

    Final product types

    • UV-cured wood coatings for industrial flooring
    • Radiation-cured inks for food packaging and labeling
    • Adhesives for electronics assembly
    • Clear and pigmented automotive refinish coatings

    3. High-Performance Polymer Additive

    Producers of specialty engineering plastics add 4-Benzoylbiphenyl as a chain modifier to increase rigidity and thermal stability in polymers such as polyesters and polycarbonates. Its molecular characteristics enable fine-tuning of glass transition temperatures and mechanical properties, supporting demanding application environments in electronics and automotive parts.

    Industry compliance standards

    • UL 94 standard for flammability of plastic materials
    • ISO 527 for tensile properties of plastics
    • EU Directive 2002/72/EC for food contact plastics
    • RoHS compliance for electronics components

    Typical usage ratio

    • 0.5–3% by weight relative to primary resin
    • Precise dosage based on target thermal and mechanical properties
    • Dispersed in masterbatch prior to polymer extrusion
    • Adapted according to end-use safety and performance criteria

    Downstream process integration

    • Fed into twin-screw extruders during polymer compounding
    • Homogeneous dispersion with resin matrix required to avoid local stiffening
    • Melt-blending conducted under controlled shear and temperature conditions
    • QC performed via differential scanning calorimetry (DSC) and tensile testing

    Final product types

    • Electronics housings with enhanced heat resistance
    • Lightweight automotive under-the-hood parts
    • Durable appliance casings
    • High-performance film materials

    4. Organic Synthesis Intermediate in Pharmaceutical Development

    Pharmaceutical R&D facilities utilize 4-Benzoylbiphenyl as an advanced intermediate in the synthesis of anti-inflammatory and other bioactive compounds. Its reactivity allows specific substitution and coupling reactions, critical in producing target molecules for clinical research or pilot-scale active pharmaceutical ingredient (API) development. Reliable traceability and impurity control are strictly required throughout the supply chain.

    Industry compliance standards

    • ICH Q7 for GMP in active pharmaceutical ingredients
    • Ph. Eur. (European Pharmacopoeia) relevant API monographs
    • USP General Chapter <1043> for APIs
    • ISO 13485 for medical devices using intermediates

    Typical usage ratio

    • Step-specific usage calculated per synthesis route
    • Often used in molar excess as coupling agent, typically 1–2 equivalents
    • Adjusted to minimize side-product formation
    • Purity must match route requirements (>99.0%)

    Downstream process integration

    • Introduced during key coupling or acylation steps under inert conditions
    • Cross-coupling with arylating or alkylating agents depending on API structure
    • Residual impurities removed through flash chromatography or crystallization
    • Batch records maintained for traceability from pilot to cGMP production

    Final product types

    • Key intermediates for anti-inflammatory agents
    • Pharmaceutical research compounds
    • APIs under clinical evaluation
    • Organic reference standards for analytical labs

    5. Specialty Dye and Pigment Synthesis

    Chemical processors employ 4-Benzoylbiphenyl as an intermediate to introduce specific aromatic substituents in high-purity dyes and performance pigments. Its function in the condensation or acylation stage directly influences hue, fastness, and compatibility in downstream applications such as fiber coloring and high-grade printing inks. Consistent impurity profile is essential to avoid coloration defects and maintain reproducibility.

    Industry compliance standards

    • OEKO-TEX® Standard 100 for textile chemicals
    • ISO 787-24 for pigment purity testing
    • EN 71-3 for pigment safety in toys
    • REACH authorization for specialty colorants

    Typical usage ratio

    • 5–15% depending on pigment backbone synthesis route
    • Fine-tuned to achieve targeted chromatic intensity
    • Batch size and scale impact optimal addition levels
    • Monitored to control secondary by-product formation

    Downstream process integration

    • Added during aromatic condensation or acylation stages
    • Reaction under temperature-controlled, closed reactors
    • Follow-up purification via phase separation and chromatography
    • QC with HPLC ensures trace impurities remain below detection limits

    Final product types

    • Saturated dyes for synthetic fiber coloration
    • Industrial-grade printing inks
    • Performance pigments for plastics and coatings
    • Color concentrates for film and fiber extrusion

    6. Optical Material Monomer for Advanced Polymers

    Producers of specialty optical polymers use 4-Benzoylbiphenyl as a functional monomer for improving refractive index and heat distortion resistance. Its integration supports high-clarity, durable polymeric materials in lenses, fiber optics, and imaging systems, where material traceability and batch-to-batch consistency directly impact downstream optical quality performance standards.

    Industry compliance standards

    • ISO 1183 for polymer density
    • ASTM D1003 for haze and clarity
    • IEC 60825 for optical safety
    • RoHS compliance for electronics grade materials

    Typical usage ratio

    • 0.2–1.5% of total monomer blend depending on target index
    • Optimized to balance refractive index versus processing stability
    • Varied slightly with end-use thickness and optical requirements
    • QC at each step ensures consistent molecular weight distribution

    Downstream process integration

    • Fed into melt or solution polymerization reactors
    • Reacts during chain extension or copolymerization stages
    • Processed under nitrogen to maintain optical clarity
    • Post-polymerization annealing helps achieve high-end clarity

    Final product types

    • Optical-grade polymer lenses
    • Precision fiber optic sheathing
    • Imaging equipment light guides
    • Ophthalmic device housings
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    Certification & Compliance
    More Introduction

    4-Benzoylbiphenyl: Reliable Performance for Industrial Success

    A Practical Look at 4-Benzoylbiphenyl

    Over the years in chemical manufacturing, we have seen raw material quality and reliability drive real downstream results. 4-Benzoylbiphenyl (CAS: 2128-93-0, C19H14O) is a compound our team has been producing for years, drawing on genuine production expertise and scrutiny of batch repeatability. With a melting point around 119-123°C and a molecular weight of 242.32 g/mol, its physical and chemical properties support consistent outcomes batch after batch.

    Within the factory, the adoption of 4-Benzoylbiphenyl emerged from decades of working with aromatic ketones. Its structure—a biphenyl backbone joined to a benzoyl group at the para position—offers more than just a nuanced molecular formula. We regularly validate purity using HPLC and NMR, achieving results above 99% for demanding industrial requirements. The detailed control we exercise over its crystallization and drying processes has been shaped by years of close feedback from partner companies relying on stable performance.

    Why 4-Benzoylbiphenyl Matters in Real-World Application

    We have supplied 4-Benzoylbiphenyl to clients ranging from specialty intermediate producers to research and development laboratories. Its principal value shows up wherever photoinitiating efficiency or structural consistency are required. 4-Benzoylbiphenyl serves as a core ingredient in the formulation of photoinitiators, especially for UV-curable coatings, adhesives, and inks. These sectors prioritize precision and stability—not only over the short term, but through the life cycle of the process line or end product.

    In practice, formulation scientists look for consistent melting and dissolution behavior. Through regular collaboration with scale-up teams, our technical staff has learned that poorly defined melting profiles or unpredictable solubility cause headaches downstream—delayed production, loss of material, unpredictable polymerization rates. We have established strict controls in our reactors and drying ovens to guarantee that these problems stay out of the end user’s path.

    Manufacturing Perspective: Specifics Set This Product Apart

    In our experience, the value of 4-Benzoylbiphenyl does not come down to chemistry alone. Handling characteristics, color stability, surface cleanliness, and trace impurity levels all affect customer satisfaction. Users in optoelectronics and advanced polymer synthesis routinely point to lot-to-lot reproducibility as a source of trust. We have traced common contaminants: triphenylmethane byproducts, oxidized biphenyls, and unreacted starting material all threaten to degrade bulk outcomes, so each batch leaves the plant only after passing GC and MS panel checks.

    Surface yellowing during storage has in the past prompted changes to our packaging process. Real-world feedback prompted us to introduce light-proof, airtight containers and employ faster transfer from crystallizer to storage. Every chemist in our operation understands that visible quality and specification conformity must coexist. The work does not end with certificates—it is about hands-on inspection, repeated running of IR spectra, and cross-checking against previous lots. We expect and deliver colorless to faintly yellow crystals, always free from dust and polymerized contaminants.

    The Role of 4-Benzoylbiphenyl in Photochemistry

    A distinguishing strength of 4-Benzoylbiphenyl is its photoreactivity—derived from conjugation between the biphenyl and benzoyl units. Our teams keep a close eye on this property, because even a small deviation from standard UV absorptivity changes real-world curing speeds. In the context of photoinitiators, customers building printing resins or coatings often rely on this compound as a crucial performance component.

    A practical proof of its importance comes from one major customer in UV-cured adhesives: a replacement trial involving structurally similar aryl ketones immediately led to poor surface cure and adhesion faults. We worked directly with their development chemists to compare rates of radical generation and kinetic profiles. Only 4-Benzoylbiphenyl at the required purity allowed them to maintain uniform polymerization under their target lamp energies. Feedback like this underscores that not all aromatic ketones perform equivalently—a theme echoed throughout our manufacturing story.

    Making the Product Work for the End-User

    End users appreciate more than just purity statistics. Flow properties during feeding, minimal fines, and minimized dust are crucial in automated dosing lines, especially in large-scale ink production. Early batches, years ago, generated excess fines, jamming valves and causing operator headaches on the line. Addressing this brought us back to fundamental crystallization control and particle sizing. Today, our product line achieves tight granulometry with minimal attrition. That comes directly from practical investments in screening, vibration, and controlled milling setups—an evolution tied to long-term relationships with process engineers, not simply optimization on paper.

    One recurring concern for those introducing new batches of 4-Benzoylbiphenyl is material consistency over time. Unlike many trade-sourced lots, material from our reactors follows a documented, repeatable production pathway. Operators pull regular in-process samples, test for correct melting range, and visually inspect each shipment. The resulting track record for process reliability is as important as any marketing claim, and it underpins why many users gradually consolidate supply from those who actually produce, not redistribute, the chemistry.

    Comparing with Related Products from a Manufacturer’s View

    Customer requests for substitutes sometimes lead to suggestions like benzoin, benzil, 4-acetylbiphenyl, or alpha-phenylacetophenone. Each of these offers related core structures, but with nuanced behavioral differences in polymer chemistry, photoreactivity, or material handling. For example, benzil (1,2-diphenylethane-1,2-dione) departs from 4-Benzoylbiphenyl in its dione functionality, which means different radical generation and curing pathways. In side-by-side trials, operators often note slower curing kinetics or altered yellowing patterns.

    There are distinct challenges with some alternatives. 4-Acetylbiphenyl may look convenient due to lower cost, but its electron distribution prevents the same efficient photoinitiation under comparable lamp outputs. 4-Benzoylbiphenyl excels in deeper and more uniform curing, which our customers observing crosslinking performance have proven in multiple series of applications tests. Moreover, our years processing biphenyl derivatives have shown that certain side products prominent in other syntheses—like catalytically induced phenolic residues—rarely trouble our end product, largely due to both source control of reagents and trained process handling.

    Safety, Handling Experience, and Environmental Commitments

    In chemical production, practicality extends far beyond meeting material specifications. Plant workers need clear documentation and direct experience to handle even moderately hazardous substances safely. 4-Benzoylbiphenyl, while not the most aggressive compound, still deserves proper respect—closed systems, point-source ventilation at loading stations, protective clothing, and prompt cleanup routines. We train all staff members, not simply to check boxes, but because experience has shown the risks posed by accumulated fines or solvent residues can escalate during multi-shift production.

    Over the past few years, customer interest in minimizing process waste and solvent residues has overlapped with regulatory changes. Our facility invested in improved solvent recovery and closed-loop filtration to cut down off-air volatile emissions. Downstream users increasingly ask us to document our routine waste reduction, not only as a matter of compliance, but because their own audits often require traceability back to original practices. We see ourselves as partners in supply chain transparency, and our staff regularly fields customer audits to support green chemistry commitments.

    Supporting R&D and Custom Needs

    Research customers often approach us looking for scaled trial samples, support in formulation compatibility, or guidance on rationalizing new raw materials in pilot batches. It takes a manufacturer’s insight to rapidly adjust lot sizes or specifications. Customizing crystal size, purity, or package format comes naturally to our team, which stands on a foundation of small-scale process development and scaled production capacity. An R&D scientist knows that timelines in the lab move quickly; supplying a kilogram for screening should not take weeks of negotiation or risky intermediates. Our factory shifts equipment between campaign- and batch-based runs according to needs drawn from day-to-day collaboration, not abstract market plans.

    We have learned the value of follow-up: whether in scheduling new HPLC analyses for compatibility studies or troubleshooting solubility in exotic solvents. In ultraviolet-curable resin development, even minor differences in trace impurities affect downstream results. Through direct feedback loops with R&D partners, we can track performance all the way from bench-top evaluation to plant-scale conversion. This long-term mindset has shaped our own efforts in staff training and instrument maintenance, knowing each analytical decision reverberates through the commercial value chain.

    Long-Term Stability and Reliability in the Marketplace

    The longevity of any chemical in industry depends on predictable behavior and the comfort it gives downstream producers. 4-Benzoylbiphenyl remains a go-to ingredient in photoinitiator synthesis for this reason, holding ground through cycles of new innovation and evolving regulatory pressures. We observe that engineering teams prefer sourcing from established manufacturing partners. A well-documented history of stability testing—ambient temperature storage studies, humidity cycling, long-term purity retention—provides practical evidence. Our incoming QA logs demonstrate lot stability years after packaging, with color and melting data maintained across archive samples.

    Counterfeit or uncontrolled-synthesis material circulates in some markets. We have seen firsthand the damage this can cause: nonconforming batches that jeopardize critical production lines, create unusable end-product, or fail to meet performance specifications. Experience has shown us that transparent origin and detailed process documentation remain non-negotiable, not just for regulatory needs but for user peace of mind. Confidence in source and process assures users that the intermediate functions the same today as it did in previous campaigns. Trust is built on lived results, not hypothetical lab data.

    Looking Ahead: 4-Benzoylbiphenyl in a Changing Regulatory and Technical Landscape

    Chemical production rarely stands still. In recent years, user inquiries have focused more on purity reporting, supply chain traceability, and sustainability documentation. We keep a close watch on evolving standards for REACH, RoHS, and GHS requirements—higher levels of scrutiny flow downstream to manufacturers. This affects 4-Benzoylbiphenyl both in documentation and in real operational routines: tighter in-process controls, robust impurity profiling, and improved stability data packages for each batch.

    Markets drive change too. Formulators of 3D printing resins and high-performance composites now look for advanced specifications—controlling not just melting point, but minute trace levels of colored impurities that could alter product appearance or cure exposure windows. Acting on such requests, we have invested in high-resolution chromatography, upgraded our colorimetry workstations, and added more rapid response teams for deviation tracking. These steps come not abstractly, but as practical responses to evolving customer needs.

    Focusing on Real Requirements: What Matters Most

    After decades in production, what stands out is that consistency, reliability, and openness drive industry preference. Whether supplying a standard kilogram, a container-load, or custom trial material, our operation revolves around these expectations. 4-Benzoylbiphenyl has earned its place through proven batch records, repeatable performance, and tight communication with users who count on exacting inputs for their innovation.

    Our own development and feedback, both from inside our own team and from loyal partners, shapes each new adjustment: from granularity to packaging, from environmental procedures to logistics improvement. Every year brings new challenges—fluctuating market conditions, supply chain turbulence, regulatory headwinds—but at core, a stable product with clear, transparent origin and tested manufacturing practices makes all the difference. Through these standards, we keep 4-Benzoylbiphenyl relevant and valuable in demanding industrial environments.

    Building on Experience: Why the Manufacturer’s Role Matters

    Only the actual manufacturer holds both the granular detail and the operational leverage to shape product quality. Resellers and traders may reshuffle batches or bundle similar-sounding goods, but persistent value comes from the expert at the reactor, the technician at the screening table, and the worker who ships each drum with pride in process. 4-Benzoylbiphenyl is more than a catalog entry. It is the output of years of feedback, technical improvement, and mutual learning between user and maker.

    Chemical manufacturing depends on real familiarity with both product and process. The demands from application chemists evolve, competition stiffens, and compliance questions multiply—but manufacturers who actively listen, adapt, and respond will continue offering the certainty that underpins industrial progress. 4-Benzoylbiphenyl, from our standpoint, represents the best of what careful, evidence-based production can deliver: material that simply works in practice, supported by the knowledge and commitment of those with direct responsibility for every lot.